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Items: 33

1.

Cholesterol-conjugated stapled peptides inhibit Ebola and Marburg viruses in vitro and in vivo.

Pessi A, Bixler SL, Soloveva V, Radoshitzky S, Retterer C, Kenny T, Zamani R, Gomba G, Gharabeih D, Wells J, Wetzel KS, Warren TK, Donnelly G, Van Tongeren SA, Steffens J, Duplantier AJ, Kane CD, Vicat P, Couturier V, Kester KE, Shiver J, Carter K, Bavari S.

Antiviral Res. 2019 Aug 29;171:104592. doi: 10.1016/j.antiviral.2019.104592. [Epub ahead of print]

2.

Countering Zika Virus: The USAMRIID Response.

Lowen RG, Bocan TM, Kane CD, Cazares LH, Kota KP, Ladner JT, Nasar F, Pitt L, Smith DR, Soloveva V, Sun MG, Zeng X, Bavari S.

Adv Exp Med Biol. 2018;1062:303-318. doi: 10.1007/978-981-10-8727-1_21. Review.

PMID:
29845541
3.

African and Asian Zika Virus Isolates Display Phenotypic Differences Both In Vitro and In Vivo.

Smith DR, Sprague TR, Hollidge BS, Valdez SM, Padilla SL, Bellanca SA, Golden JW, Coyne SR, Kulesh DA, Miller LJ, Haddow AD, Koehler JW, Gromowski GD, Jarman RG, Alera MTP, Yoon IK, Buathong R, Lowen RG, Kane CD, Minogue TD, Bavari S, Tesh RB, Weaver SC, Linthicum KJ, Pitt ML, Nasar F.

Am J Trop Med Hyg. 2018 Feb;98(2):432-444. doi: 10.4269/ajtmh.17-0685. Epub 2017 Dec 21.

4.

Clinical Laboratory Values as Early Indicators of Ebola Virus Infection in Nonhuman Primates.

Reisler RB, Yu C, Donofrio MJ, Warren TK, Wells JB, Stuthman KS, Garza NL, Vantongeren SA, Donnelly GC, Kane CD, Kortepeter MG, Bavari S, Cardile AP.

Emerg Infect Dis. 2017 Aug;23(8):1316-1324. doi: 10.3201/eid2308.170029.

5.

Searching for Therapeutics Against Botulinum Neurotoxins: A True Challenge for Drug Discovery.

Duplantier AJ, Kane CD, Bavari S.

Curr Top Med Chem. 2016;16(21):2330-49. Review.

PMID:
27072693
6.

Phosphatase Inhibitors Function as Novel, Broad Spectrum Botulinum Neurotoxin Antagonists in Mouse and Human Embryonic Stem Cell-Derived Motor Neuron-Based Assays.

Kiris E, Nuss JE, Stanford SM, Wanner LM, Cazares L, Maestre MF, Du HT, Gomba GY, Burnett JC, Gussio R, Bottini N, Panchal RG, Kane CD, Tessarollo L, Bavari S.

PLoS One. 2015 Jun 10;10(6):e0129264. doi: 10.1371/journal.pone.0129264. eCollection 2015.

7.

Novel therapeutic uses and formulations of botulinum neurotoxins: a patent review (2012 - 2014).

Kane CD, Nuss JE, Bavari S.

Expert Opin Ther Pat. 2015 Jun;25(6):675-90. doi: 10.1517/13543776.2015.1030337. Epub 2015 Apr 5. Review.

PMID:
25842964
8.

SRC family kinase inhibitors antagonize the toxicity of multiple serotypes of botulinum neurotoxin in human embryonic stem cell-derived motor neurons.

Kiris E, Burnett JC, Nuss JE, Wanner LM, Peyser BD, Du HT, Gomba GY, Kota KP, Panchal RG, Gussio R, Kane CD, Tessarollo L, Bavari S.

Neurotox Res. 2015 May;27(4):384-98. doi: 10.1007/s12640-015-9526-z. Epub 2015 Mar 18.

9.

A high content imaging assay for identification of Botulinum neurotoxin inhibitors.

Kota KP, Soloveva V, Wanner LM, Gomba G, Kiris E, Panchal RG, Kane CD, Bavari S.

J Vis Exp. 2014 Nov 14;(93):e51915. doi: 10.3791/51915.

10.

Recent advances in botulinum neurotoxin inhibitor development.

Kiris E, Burnett JC, Kane CD, Bavari S.

Curr Top Med Chem. 2014;14(18):2044-61. Review.

PMID:
25335887
11.

Recent developments in cell-based assays and stem cell technologies for botulinum neurotoxin research and drug discovery.

Kiris E, Kota KP, Burnett JC, Soloveva V, Kane CD, Bavari S.

Expert Rev Mol Diagn. 2014 Mar;14(2):153-68. doi: 10.1586/14737159.2014.867808. Epub 2014 Jan 23. Review.

12.

Efficacy and safety of mavrilimumab in subjects with rheumatoid arthritis.

Burmester GR, Weinblatt ME, McInnes IB, Porter D, Barbarash O, Vatutin M, Szombati I, Esfandiari E, Sleeman MA, Kane CD, Cavet G, Wang B, Godwood A, Magrini F; EARTH Study Group.

Ann Rheum Dis. 2013 Sep 1;72(9):1445-52. doi: 10.1136/annrheumdis-2012-202450. Epub 2012 Dec 12.

13.

Synthesis and evaluation of novel alpha-heteroaryl-phenylpropanoic acid derivatives as PPARalpha/gamma dual agonists.

Casimiro-Garcia A, Bigge CF, Davis JA, Padalino T, Pulaski J, Ohren JF, McConnell P, Kane CD, Royer LJ, Stevens KA, Auerbach B, Collard W, McGregor C, Song K.

Bioorg Med Chem. 2009 Oct 15;17(20):7113-25. doi: 10.1016/j.bmc.2009.09.001. Epub 2009 Sep 6.

PMID:
19783444
14.

Molecular characterization of novel and selective peroxisome proliferator-activated receptor alpha agonists with robust hypolipidemic activity in vivo.

Kane CD, Stevens KA, Fischer JE, Haghpassand M, Royer LJ, Aldinger C, Landschulz KT, Zagouras P, Bagley SW, Hada W, Dullea R, Hayward CM, Francone OL.

Mol Pharmacol. 2009 Feb;75(2):296-306. doi: 10.1124/mol.108.051656. Epub 2008 Oct 29.

PMID:
18971326
15.

The hydrophobic tunnel present in LOX-1 is essential for oxidized LDL recognition and binding.

Francone OL, Tu M, Royer LJ, Zhu J, Stevens K, Oleynek JJ, Lin Z, Shelley L, Sand T, Luo Y, Kane CD.

J Lipid Res. 2009 Mar;50(3):546-55. doi: 10.1194/jlr.M800474-JLR200. Epub 2008 Oct 9.

16.

Effects of modifications of the linker in a series of phenylpropanoic acid derivatives: Synthesis, evaluation as PPARalpha/gamma dual agonists, and X-ray crystallographic studies.

Casimiro-Garcia A, Bigge CF, Davis JA, Padalino T, Pulaski J, Ohren JF, McConnell P, Kane CD, Royer LJ, Stevens KA, Auerbach BJ, Collard WT, McGregor C, Fakhoury SA, Schaum RP, Zhou H.

Bioorg Med Chem. 2008 May 1;16(9):4883-907. doi: 10.1016/j.bmc.2008.03.043. Epub 2008 Mar 20.

PMID:
18394907
17.

Differential regulation of the cynomolgus, human, and rat acyl-CoA oxidase promoters by PPARalpha.

Kane CD, Francone OL, Stevens KA.

Gene. 2006 Oct 1;380(2):84-94. Epub 2006 May 26.

PMID:
16828988
18.

Proteomic analysis of calcium/calmodulin-dependent protein kinase I and IV in vitro substrates reveals distinct catalytic preferences.

Corcoran EE, Joseph JD, MacDonald JA, Kane CD, Haystead TA, Means AR.

J Biol Chem. 2003 Mar 21;278(12):10516-22. Epub 2003 Jan 21.

19.
20.

The modular nature of histone deacetylase HDAC4 confers phosphorylation-dependent intracellular trafficking.

Zhao X, Ito A, Kane CD, Liao TS, Bolger TA, Lemrow SM, Means AR, Yao TP.

J Biol Chem. 2001 Sep 14;276(37):35042-8. Epub 2001 Jul 24.

21.

Expression and localization of p53 and bcl-2 in healing wounds in diabetic and nondiabetic mice.

Kane CD, Greenhalgh DG.

Wound Repair Regen. 2000 Jan-Feb;8(1):45-58.

PMID:
10760214
22.
23.

Ca2+/calmodulin-dependent protein kinase IV and calcium signaling.

Anderson KA, Kane CD.

Biometals. 1998 Dec;11(4):331-43. Review.

PMID:
10191497
25.

Interleukin-6 production in human intestinal epithelial cells increases in association with the heat shock response.

Parikh AA, Moon MR, Kane CD, Salzman AL, Fischer JE, Hasselgren PO.

J Surg Res. 1998 Jun;77(1):40-4.

PMID:
9698530
27.
28.

Biochemical and crystallographic analyses of a portal mutant of the adipocyte lipid-binding protein.

Ory J, Kane CD, Simpson MA, Banaszak LJ, Bernlohr DA.

J Biol Chem. 1997 Apr 11;272(15):9793-801.

29.
30.

Regulation and properties of the rat Ca2+/calmodulin-dependent protein kinase IV gene and its protein products.

Means AR, Ribar TJ, Kane CD, Hook SS, Anderson KA.

Recent Prog Horm Res. 1997;52:389-406; discussion 406-7. Review.

PMID:
9238860
32.
33.

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