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Items: 1 to 50 of 518

1.

A circuit from hippocampal CA2 to lateral septum disinhibits social aggression.

Leroy F, Park J, Asok A, Brann DH, Meira T, Boyle LM, Buss EW, Kandel ER, Siegelbaum SA.

Nature. 2018 Dec;564(7735):213-218. doi: 10.1038/s41586-018-0772-0. Epub 2018 Dec 5.

PMID:
30518859
2.

Autocrine signaling by an Aplysia neurotrophin forms a presynaptic positive feedback loop.

Jin I, Udo H, Nicholls R, Zhu H, Kandel ER, Hawkins RD.

Proc Natl Acad Sci U S A. 2018 Nov 20;115(47):E11168-E11177. doi: 10.1073/pnas.1810649115. Epub 2018 Nov 5.

PMID:
30397154
3.

Molecular Mechanisms of the Memory Trace.

Asok A, Leroy F, Rayman JB, Kandel ER.

Trends Neurosci. 2019 Jan;42(1):14-22. doi: 10.1016/j.tins.2018.10.005. Epub 2018 Oct 31. Review.

PMID:
30391015
4.

Anterograde and retrograde signaling by an Aplysia neurotrophin forms a transsynaptic functional unit.

Jin I, Udo H, Kassabov S, Kosmidis S, Zhu H, Kandel ER, Hawkins RD.

Proc Natl Acad Sci U S A. 2018 Nov 13;115(46):E10951-E10960. doi: 10.1073/pnas.1810650115. Epub 2018 Oct 30.

PMID:
30377269
5.

RbAp48 Protein Is a Critical Component of GPR158/OCN Signaling and Ameliorates Age-Related Memory Loss.

Kosmidis S, Polyzos A, Harvey L, Youssef M, Denny CA, Dranovsky A, Kandel ER.

Cell Rep. 2018 Oct 23;25(4):959-973.e6. doi: 10.1016/j.celrep.2018.09.077.

6.

Adolescent cannabinoid exposure induces irritability-like behavior and cocaine cross-sensitization without affecting the escalation of cocaine self-administration in adulthood.

Kononoff J, Melas PA, Kallupi M, de Guglielmo G, Kimbrough A, Scherma M, Fadda P, Kandel DB, Kandel ER, George O.

Sci Rep. 2018 Sep 17;8(1):13893. doi: 10.1038/s41598-018-31921-5.

7.

Designing a norepinephrine optical tracer for imaging individual noradrenergic synapses and their activity in vivo.

Dunn M, Henke A, Clark S, Kovalyova Y, Kempadoo KA, Karpowicz RJ Jr, Kandel ER, Sulzer D, Sames D.

Nat Commun. 2018 Jul 19;9(1):2838. doi: 10.1038/s41467-018-05075-x.

8.

Impaired recruitment of dopamine neurons during working memory in mice with striatal D2 receptor overexpression.

Duvarci S, Simpson EH, Schneider G, Kandel ER, Roeper J, Sigurdsson T.

Nat Commun. 2018 Jul 19;9(1):2822. doi: 10.1038/s41467-018-05214-4.

9.

The Class II Histone Deacetylase Hypothesis of Addiction.

Griffin EA Jr, Melas PA, Kandel DB, Kandel ER.

Biol Psychiatry. 2018 Aug 1;84(3):165-166. doi: 10.1016/j.biopsych.2018.06.006. Epub 2018 Jun 22. No abstract available.

PMID:
29941145
10.

Cannabinoid Modulation of Eukaryotic Initiation Factors (eIF2α and eIF2B1) and Behavioral Cross-Sensitization to Cocaine in Adolescent Rats.

Melas PA, Qvist JS, Deidda M, Upreti C, Wei YB, Sanna F, Fratta W, Scherma M, Fadda P, Kandel DB, Kandel ER.

Cell Rep. 2018 Mar 13;22(11):2909-2923. doi: 10.1016/j.celrep.2018.02.065.

11.

TIA-1 Self-Multimerization, Phase Separation, and Recruitment into Stress Granules Are Dynamically Regulated by Zn2.

Rayman JB, Karl KA, Kandel ER.

Cell Rep. 2018 Jan 2;22(1):59-71. doi: 10.1016/j.celrep.2017.12.036.

12.

Prior alcohol use enhances vulnerability to compulsive cocaine self-administration by promoting degradation of HDAC4 and HDAC5.

Griffin EA Jr, Melas PA, Zhou R, Li Y, Mercado P, Kempadoo KA, Stephenson S, Colnaghi L, Taylor K, Hu MC, Kandel ER, Kandel DB.

Sci Adv. 2017 Nov 1;3(11):e1701682. doi: 10.1126/sciadv.1701682. eCollection 2017 Nov.

13.

Erratum: Functional Prions in the Brain.

Rayman JB, Kandel ER.

Cold Spring Harb Perspect Biol. 2017 Aug 1;9(8). pii: a033597. doi: 10.1101/cshperspect.a033597. No abstract available.

14.

Functional Prions in the Brain.

Rayman JB, Kandel ER.

Cold Spring Harb Perspect Biol. 2017 Jan 3;9(1). pii: a023671. doi: 10.1101/cshperspect.a023671. Review. Erratum in: Cold Spring Harb Perspect Biol. 2017 Aug 1;9(8):.

15.

TIA-1 Is a Functional Prion-Like Protein.

Rayman JB, Kandel ER.

Cold Spring Harb Perspect Biol. 2017 May 1;9(5). pii: a030718. doi: 10.1101/cshperspect.a030718. Review.

PMID:
28003185
16.

Dopamine release from the locus coeruleus to the dorsal hippocampus promotes spatial learning and memory.

Kempadoo KA, Mosharov EV, Choi SJ, Sulzer D, Kandel ER.

Proc Natl Acad Sci U S A. 2016 Dec 20;113(51):14835-14840. doi: 10.1073/pnas.1616515114. Epub 2016 Dec 7.

17.

Roles for small noncoding RNAs in silencing of retrotransposons in the mammalian brain.

Nandi S, Chandramohan D, Fioriti L, Melnick AM, Hébert JM, Mason CE, Rajasethupathy P, Kandel ER.

Proc Natl Acad Sci U S A. 2016 Nov 8;113(45):12697-12702. doi: 10.1073/pnas.1609287113. Epub 2016 Oct 24.

18.

ApCPEB4, a non-prion domain containing homolog of ApCPEB, is involved in the initiation of long-term facilitation.

Lee SH, Shim J, Cheong YH, Choi SL, Jun YW, Lee SH, Chae YS, Han JH, Lee YS, Lee JA, Lim CS, Si K, Kassabov S, Antonov I, Kandel ER, Kaang BK, Jang DJ.

Mol Brain. 2016 Oct 22;9(1):91.

19.

The Role of Functional Prion-Like Proteins in the Persistence of Memory.

Si K, Kandel ER.

Cold Spring Harb Perspect Biol. 2016 Apr 1;8(4):a021774. doi: 10.1101/cshperspect.a021774. Review.

20.

PP2A methylation controls sensitivity and resistance to β-amyloid-induced cognitive and electrophysiological impairments.

Nicholls RE, Sontag JM, Zhang H, Staniszewski A, Yan S, Kim CY, Yim M, Woodruff CM, Arning E, Wasek B, Yin D, Bottiglieri T, Sontag E, Kandel ER, Arancio O.

Proc Natl Acad Sci U S A. 2016 Mar 22;113(12):3347-52. doi: 10.1073/pnas.1521018113. Epub 2016 Mar 7.

21.

Dopamine Regulation of Amygdala Inhibitory Circuits for Expression of Learned Fear.

Kwon OB, Lee JH, Kim HJ, Lee S, Lee S, Jeong MJ, Kim SJ, Jo HJ, Ko B, Chang S, Park SK, Choi YB, Bailey CH, Kandel ER, Kim JH.

Neuron. 2015 Oct 21;88(2):378-89. doi: 10.1016/j.neuron.2015.09.001. Epub 2015 Sep 24.

22.

Improving temporal cognition by enhancing motivation.

Avlar B, Kahn JB, Jensen G, Kandel ER, Simpson EH, Balsam PD.

Behav Neurosci. 2015 Oct;129(5):576-88. doi: 10.1037/bne0000083. Epub 2015 Aug 10.

23.

Correction to Ward et al. (2015).

Ward RD, Winiger V, Higa KK, Kahn JB, Kandel ER, Balsam PD, Simpson EH.

Behav Neurosci. 2015 Aug;129(4):379. doi: 10.1037/bne0000085.

24.

Social behavior in a genetic model of dopamine dysfunction at different neurodevelopmental time points.

Kabitzke PA, Simpson EH, Kandel ER, Balsam PD.

Genes Brain Behav. 2015 Sep;14(7):503-15. doi: 10.1111/gbb.12233. Epub 2015 Aug 25.

25.

Orbitofrontal cortex mediates the differential impact of signaled-reward probability on discrimination accuracy.

Ward RD, Winiger V, Kandel ER, Balsam PD, Simpson EH.

Front Neurosci. 2015 Jun 23;9:230. doi: 10.3389/fnins.2015.00230. eCollection 2015.

26.

Structural Components of Synaptic Plasticity and Memory Consolidation.

Bailey CH, Kandel ER, Harris KM.

Cold Spring Harb Perspect Biol. 2015 Jul 1;7(7):a021758. doi: 10.1101/cshperspect.a021758. Review.

27.

MicroRNA-22 Gates Long-Term Heterosynaptic Plasticity in Aplysia through Presynaptic Regulation of CPEB and Downstream Targets.

Fiumara F, Rajasethupathy P, Antonov I, Kosmidis S, Sossin WS, Kandel ER.

Cell Rep. 2015 Jun 30;11(12):1866-75. doi: 10.1016/j.celrep.2015.05.034. Epub 2015 Jun 18.

28.

The CPEB3 Protein Is a Functional Prion that Interacts with the Actin Cytoskeleton.

Stephan JS, Fioriti L, Lamba N, Colnaghi L, Karl K, Derkatch IL, Kandel ER.

Cell Rep. 2015 Jun 23;11(11):1772-85. doi: 10.1016/j.celrep.2015.04.060. Epub 2015 Jun 11.

29.

SUMOylation Is an Inhibitory Constraint that Regulates the Prion-like Aggregation and Activity of CPEB3.

Drisaldi B, Colnaghi L, Fioriti L, Rao N, Myers C, Snyder AM, Metzger DJ, Tarasoff J, Konstantinov E, Fraser PE, Manley JL, Kandel ER.

Cell Rep. 2015 Jun 23;11(11):1694-702. doi: 10.1016/j.celrep.2015.04.061. Epub 2015 Jun 11.

30.

The Persistence of Hippocampal-Based Memory Requires Protein Synthesis Mediated by the Prion-like Protein CPEB3.

Fioriti L, Myers C, Huang YY, Li X, Stephan JS, Trifilieff P, Colnaghi L, Kosmidis S, Drisaldi B, Pavlopoulos E, Kandel ER.

Neuron. 2015 Jun 17;86(6):1433-48. doi: 10.1016/j.neuron.2015.05.021. Epub 2015 Jun 11.

31.

The impact of motivation on cognitive performance in an animal model of the negative and cognitive symptoms of schizophrenia.

Ward RD, Winiger V, Higa KK, Kahn JB, Kandel ER, Balsam PD, Simpson EH.

Behav Neurosci. 2015 Jun;129(3):292-9. doi: 10.1037/bne0000051. Epub 2015 Apr 27. Erratum in: Behav Neurosci. 2015 Aug;129(4):379.

32.

Increased dopamine D2 receptor activity in the striatum alters the firing pattern of dopamine neurons in the ventral tegmental area.

Krabbe S, Duda J, Schiemann J, Poetschke C, Schneider G, Kandel ER, Liss B, Roeper J, Simpson EH.

Proc Natl Acad Sci U S A. 2015 Mar 24;112(12):E1498-506. doi: 10.1073/pnas.1500450112. Epub 2015 Feb 9.

33.

The regulation of transcription in memory consolidation.

Alberini CM, Kandel ER.

Cold Spring Harb Perspect Biol. 2014 Dec 4;7(1):a021741. doi: 10.1101/cshperspect.a021741. Review.

34.

A molecular basis for nicotine as a gateway drug.

Kandel DB, Kandel ER.

N Engl J Med. 2014 Nov 20;371(21):2038-9. doi: 10.1056/NEJMc1411785. No abstract available.

PMID:
25409384
35.

Differential contribution of TRPM4 and TRPM5 nonselective cation channels to the slow afterdepolarization in mouse prefrontal cortex neurons.

Lei YT, Thuault SJ, Launay P, Margolskee RF, Kandel ER, Siegelbaum SA.

Front Cell Neurosci. 2014 Sep 4;8:267. doi: 10.3389/fncel.2014.00267. eCollection 2014.

36.

Shattuck Lecture. A molecular basis for nicotine as a gateway drug.

Kandel ER, Kandel DB.

N Engl J Med. 2014 Sep 4;371(10):932-43. doi: 10.1056/NEJMsa1405092. No abstract available.

37.

Huntingtin is critical both pre- and postsynaptically for long-term learning-related synaptic plasticity in Aplysia.

Choi YB, Kadakkuzha BM, Liu XA, Akhmedov K, Kandel ER, Puthanveettil SV.

PLoS One. 2014 Jul 23;9(7):e103004. doi: 10.1371/journal.pone.0103004. eCollection 2014.

38.

Learning-induced and stathmin-dependent changes in microtubule stability are critical for memory and disrupted in ageing.

Uchida S, Martel G, Pavlowsky A, Takizawa S, Hevi C, Watanabe Y, Kandel ER, Alarcon JM, Shumyatsky GP.

Nat Commun. 2014 Jul 10;5:4389. doi: 10.1038/ncomms5389.

39.

Functional role of Tia1/Pub1 and Sup35 prion domains: directing protein synthesis machinery to the tubulin cytoskeleton.

Li X, Rayman JB, Kandel ER, Derkatch IL.

Mol Cell. 2014 Jul 17;55(2):305-18. doi: 10.1016/j.molcel.2014.05.027. Epub 2014 Jun 26.

40.

The molecular and systems biology of memory.

Kandel ER, Dudai Y, Mayford MR.

Cell. 2014 Mar 27;157(1):163-86. doi: 10.1016/j.cell.2014.03.001. Review.

41.

Genetic variation in COMT activity impacts learning and dopamine release capacity in the striatum.

Simpson EH, Morud J, Winiger V, Biezonski D, Zhu JP, Bach ME, Malleret G, Polan HJ, Ng-Evans S, Phillips PE, Kellendonk C, Kandel ER.

Learn Mem. 2014 Mar 17;21(4):205-14. doi: 10.1101/lm.032094.113.

42.

D1/D5 receptors and histone deacetylation mediate the Gateway Effect of LTP in hippocampal dentate gyrus.

Huang YY, Levine A, Kandel DB, Yin D, Colnaghi L, Drisaldi B, Kandel ER.

Learn Mem. 2014 Feb 18;21(3):153-60. doi: 10.1101/lm.032292.113.

43.

Selective overexpression of dopamine D3 receptors in the striatum disrupts motivation but not cognition.

Simpson EH, Winiger V, Biezonski DK, Haq I, Kandel ER, Kellendonk C.

Biol Psychiatry. 2014 Nov 15;76(10):823-31. doi: 10.1016/j.biopsych.2013.11.023. Epub 2013 Dec 5.

44.

Republication of The Journal of Physiology (2009) 587, 2733-2741: an introduction to the work of David Hubel and Torsten Wiesel.

Kandel ER.

J Physiol. 2014 Jan 1;592(1):2-10. doi: 10.1113/jphysiol.2013.268060_2. No abstract available.

45.

Molecular mechanism for age-related memory loss: the histone-binding protein RbAp48.

Pavlopoulos E, Jones S, Kosmidis S, Close M, Kim C, Kovalerchik O, Small SA, Kandel ER.

Sci Transl Med. 2013 Aug 28;5(200):200ra115. doi: 10.1126/scitranslmed.3006373.

46.

Prefrontal cortex HCN1 channels enable intrinsic persistent neural firing and executive memory function.

Thuault SJ, Malleret G, Constantinople CM, Nicholls R, Chen I, Zhu J, Panteleyev A, Vronskaya S, Nolan MF, Bruno R, Siegelbaum SA, Kandel ER.

J Neurosci. 2013 Aug 21;33(34):13583-99. doi: 10.1523/JNEUROSCI.2427-12.2013.

47.

Neuroscience thinks big (and collaboratively).

Kandel ER, Markram H, Matthews PM, Yuste R, Koch C.

Nat Rev Neurosci. 2013 Sep;14(9):659-64. doi: 10.1038/nrn3578. Review.

PMID:
23958663
48.

New mechanisms in memory storage: piRNAs and epigenetics.

Landry CD, Kandel ER, Rajasethupathy P.

Trends Neurosci. 2013 Sep;36(9):535-42. doi: 10.1016/j.tins.2013.05.004. Epub 2013 Jul 1. Review.

PMID:
23827695
49.

Ancient origin of somatic and visceral neurons.

Nomaksteinsky M, Kassabov S, Chettouh Z, Stoeklé HC, Bonnaud L, Fortin G, Kandel ER, Brunet JF.

BMC Biol. 2013 Apr 30;11:53. doi: 10.1186/1741-7007-11-53.

50.

Nicotine primes the effect of cocaine on the induction of LTP in the amygdala.

Huang YY, Kandel DB, Kandel ER, Levine A.

Neuropharmacology. 2013 Nov;74:126-34. doi: 10.1016/j.neuropharm.2013.03.031. Epub 2013 Apr 15.

PMID:
23597510

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