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Items: 1 to 50 of 728

1.

Adolescent cannabinoid exposure induces irritability-like behavior and cocaine cross-sensitization without affecting the escalation of cocaine self-administration in adulthood.

Kononoff J, Melas PA, Kallupi M, de Guglielmo G, Kimbrough A, Scherma M, Fadda P, Kandel DB, Kandel ER, George O.

Sci Rep. 2018 Sep 17;8(1):13893. doi: 10.1038/s41598-018-31921-5.

2.

Inhibition of the aryl hydrocarbon receptor/polyamine biosynthesis axis suppresses multiple myeloma.

Bianchi-Smiraglia A, Bagati A, Fink EE, Affronti HC, Lipchick BC, Moparthy S, Long MD, Rosario SR, Lightman SM, Moparthy K, Wolff DW, Yun DH, Han Z, Polechetti A, Roll MV, Gitlin II, Leonova KI, Rowsam AM, Kandel ES, Gudkov AV, Bergsagel PL, Lee KP, Smiraglia DJ, Nikiforov MA.

J Clin Invest. 2018 Sep 10. pii: 70712. doi: 10.1172/JCI70712. [Epub ahead of print]

3.

Designing a norepinephrine optical tracer for imaging individual noradrenergic synapses and their activity in vivo.

Dunn M, Henke A, Clark S, Kovalyova Y, Kempadoo KA, Karpowicz RJ Jr, Kandel ER, Sulzer D, Sames D.

Nat Commun. 2018 Jul 19;9(1):2838. doi: 10.1038/s41467-018-05075-x.

4.

Impaired recruitment of dopamine neurons during working memory in mice with striatal D2 receptor overexpression.

Duvarci S, Simpson EH, Schneider G, Kandel ER, Roeper J, Sigurdsson T.

Nat Commun. 2018 Jul 19;9(1):2822. doi: 10.1038/s41467-018-05214-4.

5.

The Class II Histone Deacetylase Hypothesis of Addiction.

Griffin EA Jr, Melas PA, Kandel DB, Kandel ER.

Biol Psychiatry. 2018 Aug 1;84(3):165-166. doi: 10.1016/j.biopsych.2018.06.006. Epub 2018 Jun 22. No abstract available.

PMID:
29941145
6.

Our Faculty for Arts and Science The Origins of Creativity by Edward O. Wilson W. W. Norton/Liveright, New York, 2017.

Kandel E.

FASEB J. 2018 May;32(5):2322-2323. doi: 10.1096/fj.180503ufm. No abstract available.

PMID:
29698118
7.

Cannabinoid Modulation of Eukaryotic Initiation Factors (eIF2α and eIF2B1) and Behavioral Cross-Sensitization to Cocaine in Adolescent Rats.

Melas PA, Qvist JS, Deidda M, Upreti C, Wei YB, Sanna F, Fratta W, Scherma M, Fadda P, Kandel DB, Kandel ER.

Cell Rep. 2018 Mar 13;22(11):2909-2923. doi: 10.1016/j.celrep.2018.02.065.

8.

FOXQ1 controls the induced differentiation of melanocytic cells.

Bagati A, Bianchi-Smiraglia A, Moparthy S, Kolesnikova K, Fink EE, Kolesnikova M, Roll MV, Jowdy P, Wolff DW, Polechetti A, Yun DH, Lipchick BC, Paul LM, Wrazen B, Moparthy K, Mudambi S, Morozevich GE, Georgieva SG, Wang J, Shafirstein G, Liu S, Kandel ES, Berman AE, Box NF, Paragh G, Nikiforov MA.

Cell Death Differ. 2018 Jun;25(6):1040-1049. doi: 10.1038/s41418-018-0066-y. Epub 2018 Feb 20.

PMID:
29463842
9.

TIA-1 Self-Multimerization, Phase Separation, and Recruitment into Stress Granules Are Dynamically Regulated by Zn2.

Rayman JB, Karl KA, Kandel ER.

Cell Rep. 2018 Jan 2;22(1):59-71. doi: 10.1016/j.celrep.2017.12.036.

10.

Prior alcohol use enhances vulnerability to compulsive cocaine self-administration by promoting degradation of HDAC4 and HDAC5.

Griffin EA Jr, Melas PA, Zhou R, Li Y, Mercado P, Kempadoo KA, Stephenson S, Colnaghi L, Taylor K, Hu MC, Kandel ER, Kandel DB.

Sci Adv. 2017 Nov 1;3(11):e1701682. doi: 10.1126/sciadv.1701682. eCollection 2017 Nov.

11.

Internally ratiometric fluorescent sensors for evaluation of intracellular GTP levels and distribution.

Bianchi-Smiraglia A, Rana MS, Foley CE, Paul LM, Lipchick BC, Moparthy S, Moparthy K, Fink EE, Bagati A, Hurley E, Affronti HC, Bakin AV, Kandel ES, Smiraglia DJ, Feltri ML, Sousa R, Nikiforov MA.

Nat Methods. 2017 Oct;14(10):1003-1009. doi: 10.1038/nmeth.4404. Epub 2017 Sep 4.

12.

Gpr158 mediates osteocalcin's regulation of cognition.

Khrimian L, Obri A, Ramos-Brossier M, Rousseaud A, Moriceau S, Nicot AS, Mera P, Kosmidis S, Karnavas T, Saudou F, Gao XB, Oury F, Kandel E, Karsenty G.

J Exp Med. 2017 Oct 2;214(10):2859-2873. doi: 10.1084/jem.20171320. Epub 2017 Aug 29.

13.

Erratum: Functional Prions in the Brain.

Rayman JB, Kandel ER.

Cold Spring Harb Perspect Biol. 2017 Aug 1;9(8). pii: a033597. doi: 10.1101/cshperspect.a033597. No abstract available.

14.

The evidence for a microRNA product of human DROSHA gene.

Mechtler P, Johnson S, Slabodkin H, Cohanim AB, Brodsky L, Kandel ES.

RNA Biol. 2017 Nov 2;14(11):1508-1513. doi: 10.1080/15476286.2017.1342934. Epub 2017 Sep 5.

15.

P21-activated kinase 1 regulates resistance to BRAF inhibition in human cancer cells.

Babagana M, Johnson S, Slabodkin H, Bshara W, Morrison C, Kandel ES.

Mol Carcinog. 2017 May;56(5):1515-1525. doi: 10.1002/mc.22611. Epub 2017 Feb 23.

16.

Functional Prions in the Brain.

Rayman JB, Kandel ER.

Cold Spring Harb Perspect Biol. 2017 Jan 3;9(1). pii: a023671. doi: 10.1101/cshperspect.a023671. Review. Erratum in: Cold Spring Harb Perspect Biol. 2017 Aug 1;9(8):.

PMID:
28049644
17.

TIA-1 Is a Functional Prion-Like Protein.

Rayman JB, Kandel ER.

Cold Spring Harb Perspect Biol. 2017 May 1;9(5). pii: a030718. doi: 10.1101/cshperspect.a030718. Review.

PMID:
28003185
18.

Dopamine release from the locus coeruleus to the dorsal hippocampus promotes spatial learning and memory.

Kempadoo KA, Mosharov EV, Choi SJ, Sulzer D, Kandel ER.

Proc Natl Acad Sci U S A. 2016 Dec 20;113(51):14835-14840. doi: 10.1073/pnas.1616515114. Epub 2016 Dec 7.

19.

An RNA interference screen identifies new avenues for nephroprotection.

Zynda ER, Schott B, Gruener S, Wernher E, Nguyen GD, Ebeling M, Kandel ES.

Cell Death Differ. 2017 Jul;24(7):1306. doi: 10.1038/cdd.2016.98. Epub 2016 Nov 18.

20.

Roles for small noncoding RNAs in silencing of retrotransposons in the mammalian brain.

Nandi S, Chandramohan D, Fioriti L, Melnick AM, Hébert JM, Mason CE, Rajasethupathy P, Kandel ER.

Proc Natl Acad Sci U S A. 2016 Nov 8;113(45):12697-12702. doi: 10.1073/pnas.1609287113. Epub 2016 Oct 24.

21.

ApCPEB4, a non-prion domain containing homolog of ApCPEB, is involved in the initiation of long-term facilitation.

Lee SH, Shim J, Cheong YH, Choi SL, Jun YW, Lee SH, Chae YS, Han JH, Lee YS, Lee JA, Lim CS, Si K, Kassabov S, Antonov I, Kandel ER, Kaang BK, Jang DJ.

Mol Brain. 2016 Oct 22;9(1):91.

22.

The Role of Functional Prion-Like Proteins in the Persistence of Memory.

Si K, Kandel ER.

Cold Spring Harb Perspect Biol. 2016 Apr 1;8(4):a021774. doi: 10.1101/cshperspect.a021774. Review.

23.

PP2A methylation controls sensitivity and resistance to β-amyloid-induced cognitive and electrophysiological impairments.

Nicholls RE, Sontag JM, Zhang H, Staniszewski A, Yan S, Kim CY, Yim M, Woodruff CM, Arning E, Wasek B, Yin D, Bottiglieri T, Sontag E, Kandel ER, Arancio O.

Proc Natl Acad Sci U S A. 2016 Mar 22;113(12):3347-52. doi: 10.1073/pnas.1521018113. Epub 2016 Mar 7.

24.

An RNA interference screen identifies new avenues for nephroprotection.

Zynda ER, Schott B, Babagana M, Gruener S, Wernher E, Nguyen GD, Ebeling M, Kandel ES.

Cell Death Differ. 2016 Apr;23(4):608-15. doi: 10.1038/cdd.2015.128. Epub 2015 Nov 13. Erratum in: Cell Death Differ. 2017 Jul;24(7):1306.

25.

Dopamine Regulation of Amygdala Inhibitory Circuits for Expression of Learned Fear.

Kwon OB, Lee JH, Kim HJ, Lee S, Lee S, Jeong MJ, Kim SJ, Jo HJ, Ko B, Chang S, Park SK, Choi YB, Bailey CH, Kandel ER, Kim JH.

Neuron. 2015 Oct 21;88(2):378-89. doi: 10.1016/j.neuron.2015.09.001. Epub 2015 Sep 24.

26.

Improving temporal cognition by enhancing motivation.

Avlar B, Kahn JB, Jensen G, Kandel ER, Simpson EH, Balsam PD.

Behav Neurosci. 2015 Oct;129(5):576-88. doi: 10.1037/bne0000083. Epub 2015 Aug 10.

27.

Correction to Ward et al. (2015).

Ward RD, Winiger V, Higa KK, Kahn JB, Kandel ER, Balsam PD, Simpson EH.

Behav Neurosci. 2015 Aug;129(4):379. doi: 10.1037/bne0000085.

28.

Social behavior in a genetic model of dopamine dysfunction at different neurodevelopmental time points.

Kabitzke PA, Simpson EH, Kandel ER, Balsam PD.

Genes Brain Behav. 2015 Sep;14(7):503-15. doi: 10.1111/gbb.12233. Epub 2015 Aug 25.

29.

Orbitofrontal cortex mediates the differential impact of signaled-reward probability on discrimination accuracy.

Ward RD, Winiger V, Kandel ER, Balsam PD, Simpson EH.

Front Neurosci. 2015 Jun 23;9:230. doi: 10.3389/fnins.2015.00230. eCollection 2015.

30.

Structural Components of Synaptic Plasticity and Memory Consolidation.

Bailey CH, Kandel ER, Harris KM.

Cold Spring Harb Perspect Biol. 2015 Jul 1;7(7):a021758. doi: 10.1101/cshperspect.a021758. Review.

31.

MicroRNA-22 Gates Long-Term Heterosynaptic Plasticity in Aplysia through Presynaptic Regulation of CPEB and Downstream Targets.

Fiumara F, Rajasethupathy P, Antonov I, Kosmidis S, Sossin WS, Kandel ER.

Cell Rep. 2015 Jun 30;11(12):1866-75. doi: 10.1016/j.celrep.2015.05.034. Epub 2015 Jun 18.

32.

The CPEB3 Protein Is a Functional Prion that Interacts with the Actin Cytoskeleton.

Stephan JS, Fioriti L, Lamba N, Colnaghi L, Karl K, Derkatch IL, Kandel ER.

Cell Rep. 2015 Jun 23;11(11):1772-85. doi: 10.1016/j.celrep.2015.04.060. Epub 2015 Jun 11.

33.

SUMOylation Is an Inhibitory Constraint that Regulates the Prion-like Aggregation and Activity of CPEB3.

Drisaldi B, Colnaghi L, Fioriti L, Rao N, Myers C, Snyder AM, Metzger DJ, Tarasoff J, Konstantinov E, Fraser PE, Manley JL, Kandel ER.

Cell Rep. 2015 Jun 23;11(11):1694-702. doi: 10.1016/j.celrep.2015.04.061. Epub 2015 Jun 11.

34.

The Persistence of Hippocampal-Based Memory Requires Protein Synthesis Mediated by the Prion-like Protein CPEB3.

Fioriti L, Myers C, Huang YY, Li X, Stephan JS, Trifilieff P, Colnaghi L, Kosmidis S, Drisaldi B, Pavlopoulos E, Kandel ER.

Neuron. 2015 Jun 17;86(6):1433-48. doi: 10.1016/j.neuron.2015.05.021. Epub 2015 Jun 11.

35.

MicroRNA analysis suggests an additional level of feedback regulation in the NF-κB signaling cascade.

Mechtler P, Singhal R, Kichina JV, Bard JE, Buck MJ, Kandel ES.

Oncotarget. 2015 Jul 10;6(19):17097-106.

36.

The impact of motivation on cognitive performance in an animal model of the negative and cognitive symptoms of schizophrenia.

Ward RD, Winiger V, Higa KK, Kahn JB, Kandel ER, Balsam PD, Simpson EH.

Behav Neurosci. 2015 Jun;129(3):292-9. doi: 10.1037/bne0000051. Epub 2015 Apr 27. Erratum in: Behav Neurosci. 2015 Aug;129(4):379.

37.

Increased dopamine D2 receptor activity in the striatum alters the firing pattern of dopamine neurons in the ventral tegmental area.

Krabbe S, Duda J, Schiemann J, Poetschke C, Schneider G, Kandel ER, Liss B, Roeper J, Simpson EH.

Proc Natl Acad Sci U S A. 2015 Mar 24;112(12):E1498-506. doi: 10.1073/pnas.1500450112. Epub 2015 Feb 9.

38.

Protein kinase A type II-α regulatory subunit regulates the response of prostate cancer cells to taxane treatment.

Zynda ER, Matveev V, Makhanov M, Chenchik A, Kandel ES.

Cell Cycle. 2014;13(20):3292-301. doi: 10.4161/15384101.2014.949501.

39.

Characterization of cytoplasmic polyadenylation element binding 2 protein expression and its RNA binding activity.

Turimella SL, Bedner P, Skubal M, Vangoor VR, Kaczmarczyk L, Karl K, Zoidl G, Gieselmann V, Seifert G, Steinhäuser C, Kandel E, Theis M.

Hippocampus. 2015 May;25(5):630-42. doi: 10.1002/hipo.22399. Epub 2014 Dec 23.

PMID:
25483308
40.

A place and a grid in the sun.

Kandel E.

Cell. 2014 Dec 4;159(6):1239-42. doi: 10.1016/j.cell.2014.11.033.

41.

The regulation of transcription in memory consolidation.

Alberini CM, Kandel ER.

Cold Spring Harb Perspect Biol. 2014 Dec 4;7(1):a021741. doi: 10.1101/cshperspect.a021741. Review.

42.

A molecular basis for nicotine as a gateway drug.

Kandel DB, Kandel ER.

N Engl J Med. 2014 Nov 20;371(21):2038-9. doi: 10.1056/NEJMc1411785. No abstract available.

43.

The Gateway Hypothesis of substance abuse: developmental, biological and societal perspectives.

Kandel D, Kandel E.

Acta Paediatr. 2015 Feb;104(2):130-7. doi: 10.1111/apa.12851. Epub 2014 Dec 2. Review.

PMID:
25377988
44.

Differential contribution of TRPM4 and TRPM5 nonselective cation channels to the slow afterdepolarization in mouse prefrontal cortex neurons.

Lei YT, Thuault SJ, Launay P, Margolskee RF, Kandel ER, Siegelbaum SA.

Front Cell Neurosci. 2014 Sep 4;8:267. doi: 10.3389/fncel.2014.00267. eCollection 2014.

45.

Shattuck Lecture. A molecular basis for nicotine as a gateway drug.

Kandel ER, Kandel DB.

N Engl J Med. 2014 Sep 4;371(10):932-43. doi: 10.1056/NEJMsa1405092. No abstract available.

46.

Huntingtin is critical both pre- and postsynaptically for long-term learning-related synaptic plasticity in Aplysia.

Choi YB, Kadakkuzha BM, Liu XA, Akhmedov K, Kandel ER, Puthanveettil SV.

PLoS One. 2014 Jul 23;9(7):e103004. doi: 10.1371/journal.pone.0103004. eCollection 2014.

47.

Learning-induced and stathmin-dependent changes in microtubule stability are critical for memory and disrupted in ageing.

Uchida S, Martel G, Pavlowsky A, Takizawa S, Hevi C, Watanabe Y, Kandel ER, Alarcon JM, Shumyatsky GP.

Nat Commun. 2014 Jul 10;5:4389. doi: 10.1038/ncomms5389.

48.

Functional role of Tia1/Pub1 and Sup35 prion domains: directing protein synthesis machinery to the tubulin cytoskeleton.

Li X, Rayman JB, Kandel ER, Derkatch IL.

Mol Cell. 2014 Jul 17;55(2):305-18. doi: 10.1016/j.molcel.2014.05.027. Epub 2014 Jun 26.

49.

The molecular and systems biology of memory.

Kandel ER, Dudai Y, Mayford MR.

Cell. 2014 Mar 27;157(1):163-86. doi: 10.1016/j.cell.2014.03.001. Review.

50.

Genetic variation in COMT activity impacts learning and dopamine release capacity in the striatum.

Simpson EH, Morud J, Winiger V, Biezonski D, Zhu JP, Bach ME, Malleret G, Polan HJ, Ng-Evans S, Phillips PE, Kellendonk C, Kandel ER.

Learn Mem. 2014 Mar 17;21(4):205-14. doi: 10.1101/lm.032094.113.

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