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Items: 1 to 50 of 53

1.

Histidine 131 in presenilin 1 is the pH-sensitive residue that causes the increase in Aβ42 level in acidic pH.

Cai T, Hatano A, Kanatsu K, Tomita T.

J Biochem. 2019 Dec 9. pii: mvz110. doi: 10.1093/jb/mvz110. [Epub ahead of print]

PMID:
31816046
2.

Retrograde transport of γ-secretase from endosomes to the trans-Golgi network regulates Aβ42 production.

Kanatsu K, Hori Y, Ebinuma I, Chiu YW, Tomita T.

J Neurochem. 2018 Oct;147(1):110-123. doi: 10.1111/jnc.14477. Epub 2018 Aug 16.

3.

Molecular mechanisms of the genetic risk factors in pathogenesis of Alzheimer disease.

Kanatsu K, Tomita T.

Front Biosci (Landmark Ed). 2017 Jan 1;22:180-192. Review.

PMID:
27814610
4.

Partial loss of CALM function reduces Aβ42 production and amyloid deposition in vivo.

Kanatsu K, Hori Y, Takatori S, Watanabe T, Iwatsubo T, Tomita T.

Hum Mol Genet. 2016 Sep 15;25(18):3988-3997. doi: 10.1093/hmg/ddw239. Epub 2016 Jul 27.

PMID:
27466196
5.

Membrane trafficking and proteolytic activity of γ-secretase in Alzheimer's disease.

Kanatsu K, Tomita T.

Biol Chem. 2016 Sep 1;397(9):827-35. doi: 10.1515/hsz-2016-0146. Review.

PMID:
27390881
6.

Decreased CALM expression reduces Aβ42 to total Aβ ratio through clathrin-mediated endocytosis of γ-secretase.

Kanatsu K, Morohashi Y, Suzuki M, Kuroda H, Watanabe T, Tomita T, Iwatsubo T.

Nat Commun. 2014 Feb 28;5:3386. doi: 10.1038/ncomms4386.

PMID:
24577224
7.

IgM-immune complex glomerulonephritis associated with sarcoidosis.

Kanamori H, Ota M, Takeoka H, Osafune K, Yonezu S, Fukatsu A, Kanatsu K.

Clin Exp Nephrol. 2006 Mar;10(1):68-73.

PMID:
16544180
8.

Mucosal irritative and healing impairment action of risedronate in rat stomachs: comparison with alendronate.

Kanatsu K, Aihara E, Okayama M, Kato S, Takeuchi K.

J Gastroenterol Hepatol. 2004 May;19(5):512-20.

PMID:
15086594
9.

Ulcerogenic influence of selective cyclooxygenase-2 inhibitors in the rat stomach with adjuvant-induced arthritis.

Kato S, Ogawa Y, Kanatsu K, Okayama M, Watanabe T, Arakawa T, Takeuchi K.

J Pharmacol Exp Ther. 2002 Nov;303(2):503-9.

PMID:
12388629
10.

Protection against dextran sulfate sodium-induced colitis by microspheres of ellagic acid in rats.

Ogawa Y, Kanatsu K, Iino T, Kato S, Jeong YI, Shibata N, Takada K, Takeuchi K.

Life Sci. 2002 Jul 5;71(7):827-39.

PMID:
12074942
11.

Effect of taurine on ulcerogenic response and impaired ulcer healing induced by monochloramine in rat stomachs.

Kato S, Umeda M, Takeeda M, Kanatsu K, Takeuchi K.

Aliment Pharmacol Ther. 2002 Apr;16 Suppl 2:35-43.

12.

Protective effect of thiaton, an antispasmodic drug, against indomethacin-induced intestinal damage in rats.

Kunikata T, Miyazawa T, Kanatsu K, Kato S, Takeuchi K.

Jpn J Pharmacol. 2002 Jan;88(1):45-54.

13.

Protective effect of rebamipide on indomethacin-induced intestinal damage in rats.

Mizoguchi H, Ogawa Y, Kanatsu K, Tanaka A, Kato S, Takeuchi K.

J Gastroenterol Hepatol. 2001 Oct;16(10):1112-9.

PMID:
11686837
14.

Role of endogenous prostacyclin in gastric ulcerogenic and healing responses--a study using IP-receptor knockout mice.

Takeuchi K, Kato S, Ogawa Y, Kanatsu K, Umeda M.

J Physiol Paris. 2001 Jan-Dec;95(1-6):75-80.

PMID:
11595421
15.

Effect of polaprezinc on impaired healing of chronic gastric ulcers in adjuvant-induced arthritic rats--role of insulin-like growth factors (IGF)-1.

Kato S, Tanaka A, Ogawa Y, Kanatsu K, Seto K, Yoneda T, Takeuchi K.

Med Sci Monit. 2001 Jan-Feb;7(1):20-5.

PMID:
11208487
16.

Renal expression of insulin-like growth factor-l in acute renal failure: a preliminary report.

Nishiki M, Murakami Y, Kawaguchi M, Hashimoto R, Hatta T, Otani H, Kanatsu K, Kajiwara H, Osamura RY, Kato Y.

Clin Nephrol. 1999 Sep;52(3):148-51.

PMID:
10499309
17.

An adult-onset case of argininosuccinate synthetase deficiency presenting with atypical citrullinemia.

Osafune K, Ichikawa K, Yasui T, Sekikawa A, Takeoka H, Kanatsu K, Kohigashi K, Koshiyama H.

Intern Med. 1999 Jul;38(7):590-6.

18.

A novel apolipoprotein E mutation, E2 (Arg25Cys), in lipoprotein glomerulopathy.

Matsunaga A, Sasaki J, Komatsu T, Kanatsu K, Tsuji E, Moriyama K, Koga T, Arakawa K, Oikawa S, Saito T, Kita T, Doi T.

Kidney Int. 1999 Aug;56(2):421-7.

19.

Mesangiolytic glomerulopathy in severe congestive heart failure.

Yoshida H, Yashiro M, Liang P, Muso E, Takeuchi E, Shimada T, Sekita K, Ono T, Kanatsu K, Sugiyama T, Kawai C, Sasayama S.

Kidney Int. 1998 Apr;53(4):880-91.

20.

Demonstration of DNA replication factor C in human glomerular lesions.

Komatsu T, Kanatsu K, Kuze K, Iehara N, Takeoka H, Yamada Y, Kita T, Doi T.

Clin Nephrol. 1998 Feb;49(2):69-73.

PMID:
9524775
21.

[A case of nephrotic syndrome associated with minimal renal amyloidosis--a four-year follow-up].

Makibayashi K, Yanagita M, Kanatsu K.

Nihon Jinzo Gakkai Shi. 1997 Jul;39(5):507-11. Japanese.

PMID:
9283217
22.

Intraglomerular deposition of intact cross-linked fibrin in IgA nephropathy and Henoch-Schönlein purpura nephritis.

Ono T, Muso E, Suyama K, Oyama A, Matsushima H, Yashiro M, Kuwahara T, Yoshida H, Kanatsu K, Sasayama S.

Nephron. 1996;74(3):522-8.

PMID:
8938675
23.

Lipoprotein glomerulopathy with a new apolipoprotein E phenotype.

Komatsu T, Kanatsu K, Ochi H, Kita T, Doi T.

Am J Kidney Dis. 1995 Jun;25(6):952-3. No abstract available.

PMID:
7771495
24.

Detection of the antigenicity of the d-dimer of cross linked fibrin in the glomerulus by plasmin treatment.

Ono T, Kanatsu K, Ueda S, Matsuo T, Kuwahara T, Onoe C, Nagai H, Muso E, Sasayama S.

Kidney Int. 1994 Jul;46(1):260-5. No abstract available.

25.

Effects of an anti-platelet drug (dilazep) in IgA nephropathy: comparison of clinical effects with renal biopsy findings.

Yoshida H, Kanatsu K, Muso E, Kuwahara T, Sekita K, Ono T, Konishi N, Kanda C, Minakata T, Morimoto K, et al.

Nihon Jinzo Gakkai Shi. 1994 Apr;36(4):339-44.

PMID:
8022106
26.

[Polyneuropathy with IgM-antibody to myelin-associated glycoprotein without detectable M-protein by conventional analysis--report of a case].

Kageyama Y, Ichikawa K, Fujioka A, Kanatsu K, Saito T.

Rinsho Shinkeigaku. 1993 Feb;33(2):210-2. Japanese.

PMID:
7686455
27.

Infected abdominal aortic aneurysm due to Salmonella: CT evaluation.

Kario K, Mizuno Y, Kanatsu K, Tankawa H, Ikeda M.

Clin Imaging. 1991 Oct-Dec;15(4):261-4. Review.

PMID:
1742674
28.
29.

Relationship of intraglomerular coagulation and platelet aggregation to glomerular sclerosis.

Ono T, Kanatsu K, Doi T, Sekita K, Onoe C, Nagai H, Muso E, Yoshida H, Tamura T, Kawai C.

Nephron. 1991;58(4):429-36.

PMID:
1922608
30.

[A case of chronic recurrent portal systemic encephalopathy showing marked diurnal fluctuation of blood ammonia level complicated with central pontine myelinolysis].

Kario K, Kanatsu K, Sekita K, Onoe C, Fujioka A, Kageyama K, Ichikawa K, Tankawa H.

Nihon Naika Gakkai Zasshi. 1989 Aug;78(8):1172-80. Japanese. No abstract available.

PMID:
2809388
31.

Ultrastructural distribution of von Willebrand factor in human glomerular diseases.

Ono T, Kanatsu K, Doi T, Sekita K, Onoe C, Nagai H, Muso E, Yoshida H, Tamura T, Kawai C.

Nephron. 1989;53(4):311-6.

PMID:
2689898
32.

Immunoelectron microscopic localization of fibrin-related antigen in human glomerular diseases.

Ono T, Kanatsu K, Doi T, Sekita K, Nagai H, Muso E, Yoshida H, Tamura T, Kawai C.

Nephron. 1989;52(3):238-43.

PMID:
2662049
33.

Immunopathological correlations of circulating immune complexes and anti-DNA antibodies to glomerular lesions in systemic lupus erythematosus.

Muso E, Yoshida H, Sekita K, Konishi N, Tamura T, Kanatsu K, Kawai C, Hamashima Y.

Nihon Jinzo Gakkai Shi. 1987 May;29(5):501-9. No abstract available.

PMID:
3309406
34.

Clinicopathological study of patients with mesangial isolated C3d deposition in various glomerular diseases.

Doi T, Kanatsu K, Suehiro F, Nagai H, Yoshida H, Hamashima Y.

Nephron. 1987;46(2):188-93.

PMID:
3496550
35.

Peculiar round structures in the renal medulla in three patients with Bartter's syndrome.

Kuwahara T, Kanatsu K, Doi T, Sekita K, Kataoka Y, Nagai H, Ohhashi H, Tamura T, Kawai C.

Nihon Jinzo Gakkai Shi. 1986 Mar;28(3):319-26. No abstract available.

PMID:
3723865
36.

Dynamic changes in plasma inactive renin levels in Bartter's syndrome after administration of captopril and angiotensin II.

Nagai H, Matsunaga M, Ogawa K, Pak CH, Kanatsu K, Hara A, Kono T, Kawai C.

Clin Exp Pharmacol Physiol. 1986 Jan;13(1):69-75.

PMID:
3519017
37.

[Relationship between complement components (C3) depositions and glomerular injury in IgA nephropathy].

Ono T, Doi T, Nagai H, Suehiro F, Kanatsu K.

Nihon Jinzo Gakkai Shi. 1985 Jun;27(6):781-8. Japanese. No abstract available.

PMID:
3908756
38.

Distribution of IgG subclasses in membranous nephropathy.

Doi T, Mayumi M, Kanatsu K, Suehiro F, Hamashima Y.

Clin Exp Immunol. 1984 Oct;58(1):57-62.

39.

High level of plasma inactive renin in Bartter's syndrome.

Nagai H, Matsunaga M, Ogawa K, Kuwahara T, Kanatsu K, Pak CH, Hara A, Tamura T, Kono T, Kawai C.

Jpn Circ J. 1984 Jul;48(7):633-7.

PMID:
6381782
40.

Detection of IgA class circulating immune complexes bound to anti-C3d antibody in patients with IgA nephropathy.

Doi T, Kanatsu K, Sekita K, Yoshida H, Nagai H, Hamashima Y.

J Immunol Methods. 1984 Apr 13;69(1):95-104.

PMID:
6371143
41.
42.

2 cases of potassium bromate poisoning requiring long-term hemodialysis therapy for irreversible tubular damage.

Kuwahara T, Ikehara Y, Kanatsu K, Doi T, Nagai H, Nakayashiki H, Tamura T, Kawai C.

Nephron. 1984;37(4):278-80. No abstract available.

PMID:
6462318
43.

Demonstration of C3d deposits in membranous nephropathy.

Doi T, Kanatsu K, Nagai H, Suehiro F, Kuwahara T, Hamashima Y.

Nephron. 1984;37(4):232-5.

PMID:
6379483
44.

Immunoelectron microscopic studies of IgA nephropathy.

Doi T, Kanatsu K, Nagai H, Kohrogi N, Kuwahara T, Hamashima Y.

Nephron. 1984;36(4):246-51.

PMID:
6369162
45.

A comparative immunologic study of IgA nephropathy.

Kanatsu K, Doi T, Sekita K, Yoshida H, Nagai H, Hamashima Y.

Am J Kidney Dis. 1983 May;2(6):618-25.

PMID:
6342374
46.

[Case of potassium bromate poisoning requiring long-term hemodialysis therapy for irreversible tubular necrosis].

Kuwahara T, Kanatsu K, Doi T, Nagai H, Oohashi H, Yoshida H.

Nihon Naika Gakkai Zasshi. 1983 Apr;72(4):452-7. Japanese. No abstract available.

PMID:
6886510
47.

An overlapping syndrome of IgA nephropathy and membranous nephropathy?

Doi T, Kanatsu K, Nagai H, Kohrogi N, Hamashima Y.

Nephron. 1983;35(1):24-30.

PMID:
6350913
48.

Circulating immune complexes of IgG, IgA, and IgM classes in various glomerular diseases.

Doi T, Kanatsu K, Sekita K, Yoshida H, Nagai H, Hamashima Y.

Nephron. 1982;32(4):335-41.

PMID:
6762505
49.

[Immune behaviour and immune supplemental therapy in chronic hemodialyzed patients (author's transl)].

Fujita Y, Inoue S, Sato E, Takase S, Inoue H, Komaba K, Goto T, Miki S, Shimazaki K, Kanatsu K, Hirouchi H, Yamanishi J, Naito H, Horiguchi S, Honjo A, Nishioka M, Sakai R.

Nihon Jinzo Gakkai Shi. 1981 Nov;23(11):1427-41. Japanese. No abstract available.

PMID:
7334723
50.

[A case of lactic acidosis with malignant lymphoma (reticulum cell sarcoma)--problems in treatment and usefulness of hemodialysis (author's transl)].

Kuwahara T, Yoshida A, Kanatsu K, Nagai H, Ito S.

Nihon Naika Gakkai Zasshi. 1980 May;69(5):548-53. Japanese. No abstract available.

PMID:
6997415

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