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Items: 1 to 50 of 513

1.

Clonal hematopoiesis by SLIT1-mutated hematopoietic stem cells due to a breakdown of the autocrine loop involving Slit1 in acquired aplastic anemia.

Hosokawa K, Mizumaki H, Elbadry MI, Saito C, Espinoza JL, Thi Thanh Dao A, Katagiri T, Harashima A, Kikuchi A, Kanai A, Matsui H, Inaba T, Taniwaki M, Yamamoto Y, Nakao S.

Leukemia. 2019 Jun 11. doi: 10.1038/s41375-019-0510-0. [Epub ahead of print] No abstract available.

PMID:
31186493
2.

A cell-based high-throughput screening method to directly examine transthyretin amyloid fibril formation at neutral pH.

Ueda M, Okada M, Mizuguchi M, Kluve-Beckerman B, Kanenawa K, Isoguchi A, Misumi Y, Tasaki M, Ueda A, Kanai A, Sasaki R, Masuda T, Inoue Y, Nomura T, Shinriki S, Shuto T, Kai H, Yamashita T, Matsui H, Benson MD, Ando Y.

J Biol Chem. 2019 Jun 5. pii: jbc.RA119.007851. doi: 10.1074/jbc.RA119.007851. [Epub ahead of print]

3.

Acute spinal cord injury is associated with mitochondrial dysfunction in mouse urothelium.

Kullmann AF, Truschel ST, Wolf-Johnston AS, McDonnell BM, Lynn AM, Kanai AJ, Kessler TM, Apodaca G, Birder LA.

Neurourol Urodyn. 2019 May 18. doi: 10.1002/nau.24037. [Epub ahead of print]

PMID:
31102563
4.

Fhod1, an actin-organizing formin family protein, is dispensable for cardiac development and function in mice.

Sanematsu F, Kanai A, Ushijima T, Shiraishi A, Abe T, Kage Y, Sumimoto H, Takeya R.

Cytoskeleton (Hoboken). 2019 Feb;76(2):219-229. doi: 10.1002/cm.21523. Epub 2019 Apr 29.

PMID:
31008549
5.

Lineage-specific RUNX2 super-enhancer activates MYC and promotes the development of blastic plasmacytoid dendritic cell neoplasm.

Kubota S, Tokunaga K, Umezu T, Yokomizo-Nakano T, Sun Y, Oshima M, Tan KT, Yang H, Kanai A, Iwanaga E, Asou N, Maeda T, Nakagata N, Iwama A, Ohyashiki K, Osato M, Sashida G.

Nat Commun. 2019 Apr 10;10(1):1653. doi: 10.1038/s41467-019-09710-z.

6.

Influence of sildenafil on the purinergic components of nerve-mediated and urothelial ATP release from the bladder of normal and spinal cord injured mice.

Chakrabarty B, Ito H, Ximenes M, Nishikawa N, Vahabi B, Kanai AJ, Pickering AE, Drake MJ, Fry CH.

Br J Pharmacol. 2019 Jul;176(13):2227-2237. doi: 10.1111/bph.14669. Epub 2019 May 11.

7.

Relaxin and fibrosis: Emerging targets, challenges, and future directions.

Kanai AJ, Konieczko EM, Bennett RG, Samuel CS, Royce SG.

Mol Cell Endocrinol. 2019 May 1;487:66-74. doi: 10.1016/j.mce.2019.02.005. Epub 2019 Feb 14. Review.

PMID:
30772373
8.

Modulation of Bladder Wall Micromotions Alters Intravesical Pressure Activity in the Isolated Bladder.

Chakrabarty B, Bijos DA, Vahabi B, Clavica F, Kanai AJ, Pickering AE, Fry CH, Drake MJ.

Front Physiol. 2019 Jan 10;9:1937. doi: 10.3389/fphys.2018.01937. eCollection 2018.

9.

Sildenafil, a phosphodiesterase type 5 inhibitor, augments sphincter bursting and bladder afferent activity to enhance storage function and voiding efficiency in mice.

Ito H, Chakrabarty B, Drake MJ, Fry CH, Kanai AJ, Pickering AE.

BJU Int. 2019 Jul;124(1):163-173. doi: 10.1111/bju.14664. Epub 2019 Feb 17.

PMID:
30636087
10.

Stress-induced autonomic dysregulation of mitochondrial function in the rat urothelium.

Kullmann FA, McDonnell BM, Wolf-Johnston AS, Kanai AJ, Shiva S, Chelimsky T, Rodriguez L, Birder LA.

Neurourol Urodyn. 2019 Feb;38(2):572-581. doi: 10.1002/nau.23876. Epub 2018 Dec 21.

PMID:
30575113
11.

Stable factor structure of the Edinburgh Postnatal Depression Scale during the whole peripartum period: Results from a Japanese prospective cohort study.

Kubota C, Inada T, Nakamura Y, Shiino T, Ando M, Aleksic B, Yamauchi A, Morikawa M, Okada T, Ohara M, Sato M, Murase S, Goto S, Kanai A, Ozaki N.

Sci Rep. 2018 Dec 5;8(1):17659. doi: 10.1038/s41598-018-36101-z.

12.

Corrigendum: Inflammation and Tissue Remodeling in the Bladder and Urethra in Feline Interstitial Cystitis.

Kullmann FA, McDonnell BM, Wolf-Johnston AS, Lynn AM, Giglio D, Getchell SE, Ruiz WG, Zabbarova IV, Ikeda Y, Kanai AJ, Roppolo JR, Bastacky SI, Apodaca G, Buffington CAT, Birder LA.

Front Syst Neurosci. 2018 Nov 8;12:58. doi: 10.3389/fnsys.2018.00058. eCollection 2018.

13.

Short-term results of intrathecal injection of low-dose bupivacaine in outpatients with chronic low back and lower extremity pain.

Kanai A, Okamoto T, Hayashi N, Shimao J, Nagahara Y, Fujii K.

Eur Spine J. 2019 Feb;28(2):250-258. doi: 10.1007/s00586-018-5801-z. Epub 2018 Oct 26.

PMID:
30367241
14.

S100P and Ezrin promote trans-endothelial migration of triple negative breast cancer cells.

Kikuchi K, McNamara KM, Miki Y, Iwabuchi E, Kanai A, Miyashita M, Ishida T, Sasano H.

Cell Oncol (Dordr). 2019 Feb;42(1):67-80. doi: 10.1007/s13402-018-0408-2. Epub 2018 Sep 22.

PMID:
30244410
15.

Impact of perceived rearing and social support on bonding failure and depression among mothers: A longitudinal study of pregnant women.

Ohara M, Nakatochi M, Okada T, Aleksic B, Nakamura Y, Shiino T, Yamauchi A, Kubota C, Morikawa M, Murase S, Goto S, Kanai A, Kato R, Ando M, Ozaki N.

J Psychiatr Res. 2018 Oct;105:71-77. doi: 10.1016/j.jpsychires.2018.09.001. Epub 2018 Sep 4.

PMID:
30205250
16.

Fibrosis and the bladder, implications for function ICI-RS 2017.

Fry CH, Kitney DG, Paniker J, Drake MJ, Kanai A, Andersson KE.

Neurourol Urodyn. 2018 Jun;37(S4):S7-S12. doi: 10.1002/nau.23725.

PMID:
30133788
17.

Ezh2 loss propagates hypermethylation at T cell differentiation-regulating genes to promote leukemic transformation.

Wang C, Oshima M, Sato D, Matsui H, Kubota S, Aoyama K, Nakajima-Takagi Y, Koide S, Matsubayashi J, Mochizuki-Kashio M, Nakano-Yokomizo T, Bai J, Nagao T, Kanai A, Iwama A, Sashida G.

J Clin Invest. 2018 Aug 31;128(9):3872-3886. doi: 10.1172/JCI94645. Epub 2018 Aug 6.

18.

Postpartum depression among women in Nagoya indirectly exposed to the Great East Japan Earthquake.

Kubota C, Okada T, Morikawa M, Nakamura Y, Yamauchi A, Ando M, Shiino T, Ohara M, Murase S, Goto S, Kanai A, Masuda T, Aleksic B, Ozaki N.

Sci Rep. 2018 Aug 2;8(1):11624. doi: 10.1038/s41598-018-30065-w.

19.

The interaction between carcinoembryonic antigen-related cell adhesion molecule 6 and human epidermal growth factor receptor 2 is associated with therapeutic efficacy of trastuzumab in breast cancer.

Iwabuchi E, Miki Y, Kanai A, Miyashita M, Kijima G, Hirakawa H, Suzuki T, Ishida T, Sasano H.

J Pathol. 2018 Nov;246(3):379-389. doi: 10.1002/path.5148. Epub 2018 Oct 4.

PMID:
30058236
20.

Involvement of TRPM4 in detrusor overactivity following spinal cord transection in mice.

Kullmann FA, Beckel JM, McDonnell B, Gauthier C, Lynn AM, Wolf-Johnston A, Kanai A, Zabbarova IV, Ikeda Y, de Groat WC, Birder LA.

Naunyn Schmiedebergs Arch Pharmacol. 2018 Nov;391(11):1191-1202. doi: 10.1007/s00210-018-1542-0. Epub 2018 Jul 27.

PMID:
30054681
21.

[Clinical Effects of Opioid Switching to Tapentadol - Retrospective Analysis of Efficacy and Adverse Effects].

Homma M, Kokubun H, Hayashi N, Kanai A, Atsuda K.

Gan To Kagaku Ryoho. 2018 Jul;45(7):1081-1086. Japanese.

PMID:
30042277
22.

Validation and Factor Analysis of the Japanese Version of the Highs Scale in Perinatal Women.

Yamauchi A, Okada T, Ando M, Morikawa M, Nakamura Y, Kubota C, Ohara M, Murase S, Goto S, Kanai A, Ozaki N.

Front Psychiatry. 2018 Jun 28;9:269. doi: 10.3389/fpsyt.2018.00269. eCollection 2018.

23.

Effects of nerve growth factor neutralization on TRP channel expression in laser-captured bladder afferent neurons in mice with spinal cord injury.

Shimizu N, Wada N, Shimizu T, Suzuki T, Takaoka EI, Kanai AJ, de Groat WC, Hirayama A, Hashimoto M, Uemura H, Yoshimura N.

Neurosci Lett. 2018 Sep 14;683:100-103. doi: 10.1016/j.neulet.2018.06.049. Epub 2018 Jun 28.

PMID:
29960052
24.

Relaxin-2 therapy reverses radiation-induced fibrosis and restores bladder function in mice.

Ikeda Y, Zabbarova IV, Birder LA, Wipf P, Getchell SE, Tyagi P, Fry CH, Drake MJ, Kanai AJ.

Neurourol Urodyn. 2018 Nov;37(8):2441-2451. doi: 10.1002/nau.23721. Epub 2018 May 28.

25.

Targeting p75 neurotrophin receptors ameliorates spinal cord injury-induced detrusor sphincter dyssynergia in mice.

Zabbarova IV, Ikeda Y, Carder EJ, Wipf P, Wolf-Johnston AS, Birder LA, Yoshimura N, Getchell SE, Almansoori K, Tyagi P, Fry CH, Drake MJ, Kanai AJ.

Neurourol Urodyn. 2018 Nov;37(8):2452-2461. doi: 10.1002/nau.23722. Epub 2018 May 28.

26.

Inflammation and Tissue Remodeling in the Bladder and Urethra in Feline Interstitial Cystitis.

Kullmann FA, McDonnell BM, Wolf-Johnston AS, Lynn AM, Giglio D, Getchell SE, Ruiz WG, Zabbarova IV, Ikeda Y, Kanai AJ, Roppolo JR, Bastacky SI, Apodaca G, Buffington CAT, Birder LA.

Front Syst Neurosci. 2018 Apr 13;12:13. doi: 10.3389/fnsys.2018.00013. eCollection 2018. Erratum in: Front Syst Neurosci. 2018 Nov 08;12:58.

27.

Corrigendum to 'Morphological Changes in Different Populations of Bladder Afferent Neurons Detected by Herpes Simplex Virus (HSV) Vectors with Cell-type-specific Promoters in Mice with Spinal Cord Injury' [Neuroscience 364 (2017) 190-201].

Shimizu N, Doyal MF, Goins WF, Kadekawa K, Wada N, Kanai AJ, de Groat WC, Hirayama A, Uemura H, Glorioso JC, Yoshimura N.

Neuroscience. 2018 Jun 15;381:161. doi: 10.1016/j.neuroscience.2018.04.021. Epub 2018 Apr 26. No abstract available.

28.

Expression of mutant Asxl1 perturbs hematopoiesis and promotes susceptibility to leukemic transformation.

Nagase R, Inoue D, Pastore A, Fujino T, Hou HA, Yamasaki N, Goyama S, Saika M, Kanai A, Sera Y, Horikawa S, Ota Y, Asada S, Hayashi Y, Kawabata KC, Takeda R, Tien HF, Honda H, Abdel-Wahab O, Kitamura T.

J Exp Med. 2018 Jun 4;215(6):1729-1747. doi: 10.1084/jem.20171151. Epub 2018 Apr 11.

29.

Nerve growth factor-dependent hyperexcitability of capsaicin-sensitive bladder afferent neurones in mice with spinal cord injury.

Shimizu T, Majima T, Suzuki T, Shimizu N, Wada N, Kadekawa K, Takai S, Takaoka E, Kwon J, Kanai AJ, de Groat WC, Tyagi P, Saito M, Yoshimura N.

Exp Physiol. 2018 Jun;103(6):896-904. doi: 10.1113/EP086951. Epub 2018 Apr 24.

30.

Role of proNGF/p75 signaling in bladder dysfunction after spinal cord injury.

Ryu JC, Tooke K, Malley SE, Soulas A, Weiss T, Ganesh N, Saidi N, Daugherty S, Saragovi U, Ikeda Y, Zabbarova I, Kanai AJ, Yoshiyama M, Farhadi HF, de Groat WC, Vizzard MA, Yoon SO.

J Clin Invest. 2018 May 1;128(5):1772-1786. doi: 10.1172/JCI97837. Epub 2018 Mar 26.

31.

A novel ASXL1-OGT axis plays roles in H3K4 methylation and tumor suppression in myeloid malignancies.

Inoue D, Fujino T, Sheridan P, Zhang YZ, Nagase R, Horikawa S, Li Z, Matsui H, Kanai A, Saika M, Yamaguchi R, Kozuka-Hata H, Kawabata KC, Yokoyama A, Goyama S, Inaba T, Imoto S, Miyano S, Xu M, Yang FC, Oyama M, Kitamura T.

Leukemia. 2018 Jun;32(6):1327-1337. doi: 10.1038/s41375-018-0083-3. Epub 2018 Mar 3.

PMID:
29556021
32.

The effect of neutralization of nerve growth factor (NGF) on bladder and urethral dysfunction in mice with spinal cord injury.

Wada N, Shimizu T, Shimizu N, de Groat WC, Kanai AJ, Tyagi P, Kakizaki H, Yoshimura N.

Neurourol Urodyn. 2018 Aug;37(6):1889-1896. doi: 10.1002/nau.23539. Epub 2018 Mar 8.

PMID:
29516546
33.

Role of fluorine in two-dimensional dichalcogenide of SnSe 2.

Kim JT, Hyeon DS, Hanzawa K, Kanai A, Kim SY, Lee YJ, Hosono H, Bang J, Lee K.

Sci Rep. 2018 Jan 26;8(1):1645. doi: 10.1038/s41598-018-20111-y.

34.

What are the origins and relevance of spontaneous bladder contractions? ICI-RS 2017.

Drake MJ, Fry CH, Hashitani H, Kirschner-Hermanns R, Rahnama'i MS, Speich JE, Tomoe H, Kanai AJ, McCloskey KD.

Neurourol Urodyn. 2018 Jun;37(S4):S13-S19. doi: 10.1002/nau.23485. Epub 2018 Jan 23.

35.

Systematic Analysis of the Binding Surfaces between tRNAs and Their Respective Aminoacyl tRNA Synthetase Based on Structural and Evolutionary Data.

Tamaki S, Tomita M, Suzuki H, Kanai A.

Front Genet. 2018 Jan 8;8:227. doi: 10.3389/fgene.2017.00227. eCollection 2017.

36.

Characterization of mouse neuro-urological dynamics in a novel decerebrate arterially perfused mouse (DAPM) preparation.

Ito H, Drake MJ, Fry CH, Kanai AJ, Pickering AE.

Neurourol Urodyn. 2018 Apr;37(4):1302-1312. doi: 10.1002/nau.23471. Epub 2018 Jan 15.

37.

Evolutionary Analysis of HIV-1 Pol Proteins Reveals Representative Residues for Viral Subtype Differentiation.

Nagata S, Imai J, Makino G, Tomita M, Kanai A.

Front Microbiol. 2017 Nov 2;8:2151. doi: 10.3389/fmicb.2017.02151. eCollection 2017.

38.

An archaeal RNA binding protein, FAU-1, is a novel ribonuclease related to rRNA stability in Pyrococcus and Thermococcus.

Ikeda Y, Okada Y, Sato A, Kanai T, Tomita M, Atomi H, Kanai A.

Sci Rep. 2017 Oct 4;7(1):12674. doi: 10.1038/s41598-017-13062-3.

39.

Evaluation of Pigment Distribution and Depth Analysis Methods for Decorative Soft Contact Lenses.

Nomura Y, Toida H, Fukui C, Kai S, Nakaoka R, Kato R, Uematsu M, Ono K, Kanai A, Haishima Y.

Eye Contact Lens. 2018 Nov;44 Suppl 2:S105-S112. doi: 10.1097/ICL.0000000000000429.

PMID:
28953599
40.

Priming of lineage-specifying genes by Bcl11b is required for lineage choice in post-selection thymocytes.

Kojo S, Tanaka H, Endo TA, Muroi S, Liu Y, Seo W, Tenno M, Kakugawa K, Naoe Y, Nair K, Moro K, Katsuragi Y, Kanai A, Inaba T, Egawa T, Venkatesh B, Minoda A, Kominami R, Taniuchi I.

Nat Commun. 2017 Sep 26;8(1):702. doi: 10.1038/s41467-017-00768-1.

41.

Morphological changes in different populations of bladder afferent neurons detected by herpes simplex virus (HSV) vectors with cell-type-specific promoters in mice with spinal cord injury.

Shimizu N, Doyal MF, Goins WF, Kadekawa K, Wada N, Kanai AJ, de Groat WC, Hirayama A, Uemura H, Glorioso JC, Yoshimura N.

Neuroscience. 2017 Nov 19;364:190-201. doi: 10.1016/j.neuroscience.2017.09.024. Epub 2017 Sep 20. Erratum in: Neuroscience. 2018 Apr 25;:.

42.

Synthesis and Evaluation of Dolastatin 10 Analogues Containing Heteroatoms on the Amino Acid Side Chains.

Dugal-Tessier J, Barnscher SD, Kanai A, Mendelsohn BA.

J Nat Prod. 2017 Sep 22;80(9):2484-2491. doi: 10.1021/acs.jnatprod.7b00359. Epub 2017 Sep 8.

PMID:
28885014
43.

Social support helps protect against perinatal bonding failure and depression among mothers: a prospective cohort study.

Ohara M, Okada T, Aleksic B, Morikawa M, Kubota C, Nakamura Y, Shiino T, Yamauchi A, Uno Y, Murase S, Goto S, Kanai A, Masuda T, Nakatochi M, Ando M, Ozaki N.

Sci Rep. 2017 Aug 25;7(1):9546. doi: 10.1038/s41598-017-08768-3.

44.

Serotonergic paraneurones in the female mouse urethral epithelium and their potential role in peripheral sensory information processing.

Kullmann FA, Chang HH, Gauthier C, McDonnell BM, Yeh JC, Clayton DR, Kanai AJ, de Groat WC, Apodaca GL, Birder LA.

Acta Physiol (Oxf). 2018 Feb;222(2). doi: 10.1111/apha.12919. Epub 2017 Aug 8.

45.

Distinct requirements for energy metabolism in mouse primordial germ cells and their reprogramming to embryonic germ cells.

Hayashi Y, Otsuka K, Ebina M, Igarashi K, Takehara A, Matsumoto M, Kanai A, Igarashi K, Soga T, Matsui Y.

Proc Natl Acad Sci U S A. 2017 Aug 1;114(31):8289-8294. doi: 10.1073/pnas.1620915114. Epub 2017 Jul 17. Erratum in: Proc Natl Acad Sci U S A. 2018 Jul 24;115(30):E7232.

46.

New Frontiers of Basic Science Research in Neurogenic Lower Urinary Tract Dysfunction.

Miyazato M, Kadekawa K, Kitta T, Wada N, Shimizu N, de Groat WC, Birder LA, Kanai AJ, Saito S, Yoshimura N.

Urol Clin North Am. 2017 Aug;44(3):491-505. doi: 10.1016/j.ucl.2017.04.014. Review.

47.

Efficacy and safety of anagrelide in childhood essential thrombocythemia.

Kanai A, Morokawa H, Matsuda K, Shimazaki E, Nakazawa Y.

Pediatr Int. 2017 Sep;59(9):1017-1018. doi: 10.1111/ped.13330. Epub 2017 Jul 14. No abstract available.

PMID:
28707720
48.

The role of capsaicin-sensitive C-fiber afferent pathways in the control of micturition in spinal-intact and spinal cord-injured mice.

Kadekawa K, Majima T, Shimizu T, Wada N, de Groat WC, Kanai AJ, Goto M, Yoshiyama M, Sugaya K, Yoshimura N.

Am J Physiol Renal Physiol. 2017 Sep 1;313(3):F796-F804. doi: 10.1152/ajprenal.00097.2017. Epub 2017 Jun 21.

49.

Relationship between maternal depression and bonding failure: A prospective cohort study of pregnant women.

Ohara M, Okada T, Kubota C, Nakamura Y, Shiino T, Aleksic B, Morikawa M, Yamauchi A, Uno Y, Murase S, Goto S, Kanai A, Masuda T, Ando M, Ozaki N.

Psychiatry Clin Neurosci. 2017 Oct;71(10):733-741. doi: 10.1111/pcn.12541. Epub 2017 Jul 7.

50.

Variations of placental migration in patients with early third trimester malposition.

Haino K, Ishii K, Kanda M, Kanai A, Hayashi S, Mitsuda N.

J Med Ultrason (2001). 2018 Jan;45(1):99-102. doi: 10.1007/s10396-017-0791-8. Epub 2017 Apr 27.

PMID:
28451775

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