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MiR-133a acts as an anti-oncogene in Hepatocellular carcinoma by inhibiting FOSL2 through TGF-β/Smad3 signaling pathway.

Sun L, Guo Z, Sun J, Li J, Dong Z, Zhang Y, Chen J, Kan Q, Yu Z.

Biomed Pharmacother. 2018 Aug 4;107:168-176. doi: 10.1016/j.biopha.2018.07.151. [Epub ahead of print]


Gut microbiome analysis as a tool towards targeted non-invasive biomarkers for early hepatocellular carcinoma.

Ren Z, Li A, Jiang J, Zhou L, Yu Z, Lu H, Xie H, Chen X, Shao L, Zhang R, Xu S, Zhang H, Cui G, Chen X, Sun R, Wen H, Lerut JP, Kan Q, Li L, Zheng S.

Gut. 2018 Jul 25. pii: gutjnl-2017-315084. doi: 10.1136/gutjnl-2017-315084. [Epub ahead of print]


Role of sodium-hydrogen exchanger isoform 1 in regulating hepatocyte apoptosis induced by hyperammonaemia.

Wang P, Wang X, Li L, Kan Q, Yu Z, Feng R, Chen Z, Shi Y, Gao J.

Gastroenterol Hepatol. 2018 Jul 19. pii: S0210-5705(18)30157-2. doi: 10.1016/j.gastrohep.2018.05.026. [Epub ahead of print] English, Spanish.


In vivo tailor-made protein corona of a prodrug-based nanoassembly fabricated by redox dual-sensitive paclitaxel prodrug for the superselective treatment of breast cancer.

Zhang D, Yang J, Guan J, Yang B, Zhang S, Sun M, Yang R, Zhang T, Zhang R, Kan Q, Zhang H, He Z, Shang L, Sun J.

Biomater Sci. 2018 Jul 18. doi: 10.1039/c8bm00548f. [Epub ahead of print]


Precisely albumin-hitchhiking tumor cell-activated reduction/oxidation-responsive docetaxel prodrugs for the hyperselective treatment of breast cancer.

Wei W, Luo C, Yang J, Sun B, Zhao D, Liu Y, Wang Y, Yang W, Kan Q, Sun J, He Z.

J Control Release. 2018 Jul 12;285:187-199. doi: 10.1016/j.jconrel.2018.07.010. [Epub ahead of print]


Ablation of MCM10 using CRISPR/Cas9 restrains the growth and migration of esophageal squamous cell carcinoma cells through inhibition of Akt signaling.

Yan J, Du P, Jia Y, Chang Z, Gan S, Xu X, Wang Y, Qin Y, Kan Q.

Onco Targets Ther. 2018 Jun 6;11:3323-3333. doi: 10.2147/OTT.S157025. eCollection 2018.


Dipeptide-modified nanoparticles to facilitate oral docetaxel delivery: new insights into PepT1-mediated targeting strategy.

Du Y, Tian C, Wang M, Huang D, Wei W, Liu Y, Li L, Sun B, Kou L, Kan Q, Liu K, Luo C, Sun J, He Z.

Drug Deliv. 2018 Nov;25(1):1403-1413. doi: 10.1080/10717544.2018.1480675.


Long Non-Coding RNA CASC2 Improves Diabetic Nephropathy by Inhibiting JNK Pathway.

Yang H, Kan QE, Su Y, Man H.

Exp Clin Endocrinol Diabetes. 2018 Jun 11. doi: 10.1055/a-0629-9958. [Epub ahead of print]


Dynamic tailoring of electromagnetic behaviors of graphene plasmonic oligomers by local chemical potential.

Ren J, Wang W, Qiu W, Qiu P, Wang Z, Lin Z, Wang JX, Kan Q, Pan JQ.

Phys Chem Chem Phys. 2018 Jun 20;20(24):16695-16703. doi: 10.1039/c8cp01281d.


Comparison between wait-and-see policy and elective neck dissection in clinically N0 cutaneous squamous cell carcinoma of head and neck.

Xiao Y, Yuan S, Liu F, Liu B, Zhu J, He W, Li W, Kan Q.

Medicine (Baltimore). 2018 Jun;97(22):e10782. doi: 10.1097/MD.0000000000010782.


The Protective Effect of Naringenin on Airway Remodeling after Mycoplasma Pneumoniae Infection by Inhibiting Autophagy-Mediated Lung Inflammation and Fibrosis.

Lin Y, Tan D, Kan Q, Xiao Z, Jiang Z.

Mediators Inflamm. 2018 Apr 4;2018:8753894. doi: 10.1155/2018/8753894. eCollection 2018.


Striking a Balance between Carbonate/Carbamate Linkage Bond- and Reduction-Sensitive Disulfide Bond-Bearing Linker for Tailored Controlled Release: In Situ Covalent-Albumin-Binding Gemcitabine Prodrugs Promote Bioavailability and Tumor Accumulation.

Zhang H, Wang K, Na K, Li D, Li Z, Zhao D, Zhong L, Wang M, Kou L, Luo C, Zhang H, Kan Q, Ding H, He Z, Sun J.

J Med Chem. 2018 Jun 14;61(11):4904-4917. doi: 10.1021/acs.jmedchem.8b00293. Epub 2018 May 24.


Disulfide Bond-Driven Oxidation- and Reduction-Responsive Prodrug Nanoassemblies for Cancer Therapy.

Sun B, Luo C, Yu H, Zhang X, Chen Q, Yang W, Wang M, Kan Q, Zhang H, Wang Y, He Z, Sun J.

Nano Lett. 2018 Jun 13;18(6):3643-3650. doi: 10.1021/acs.nanolett.8b00737. Epub 2018 May 9.


Expression and role of autophagy-associated p62 (SQSTM1) in multidrug resistant ovarian cancer.

Wang J, Garbutt C, Ma H, Gao P, Hornicek FJ, Kan Q, Shi H, Duan Z.

Gynecol Oncol. 2018 Jul;150(1):143-150. doi: 10.1016/j.ygyno.2018.04.557. Epub 2018 Apr 24.


Mitochondria-targeted prostate cancer therapy using a near-infrared fluorescence dye-monoamine oxidase A inhibitor conjugate.

Lv Q, Yang X, Wang M, Yang J, Qin Z, Kan Q, Zhang H, Wang Y, Wang D, He Z.

J Control Release. 2018 Jun 10;279:234-242. doi: 10.1016/j.jconrel.2018.04.038. Epub 2018 Apr 19. No abstract available.


Pseudospin Dependent One-Way Transmission in Graphene-Based Topological Plasmonic Crystals.

Qiu P, Qiu W, Ren J, Lin Z, Wang Z, Wang JX, Kan Q, Pan JQ.

Nanoscale Res Lett. 2018 Apr 20;13(1):113. doi: 10.1186/s11671-018-2538-x.


Bioresponsive albumin-conjugated paclitaxel prodrugs for cancer therapy.

Yang J, Lv Q, Wei W, Yang Z, Dong J, Zhang R, Kan Q, He Z, Xu Y.

Drug Deliv. 2018 Nov;25(1):807-814. doi: 10.1080/10717544.2018.1451935.


Covalently mucoadhesive amphiphilic prodrug of 5-fluorouracil for enhanced permeation and improved oral absorption.

Liu Y, Zhao D, Sun M, Wei W, Wang Y, Zhou J, Zhang R, Wang J, Zhang H, He Z, Kan Q, Sun J.

Drug Deliv Transl Res. 2018 Jun;8(3):645-656. doi: 10.1007/s13346-018-0502-z.


Colloidal lithography-based fabrication of highly-ordered nanofluidic channels with an ultra-high surface-to-volume ratio.

Wang S, Liu Y, Ge P, Kan Q, Yu N, Wang J, Nan J, Ye S, Zhang J, Xu W, Yang B.

Lab Chip. 2018 Mar 13;18(6):979-988. doi: 10.1039/c7lc01326d.


Circulating tumor DNA 5-hydroxymethylcytosine as a novel diagnostic biomarker for esophageal cancer.

Tian X, Sun B, Chen C, Gao C, Zhang J, Lu X, Wang L, Li X, Xing Y, Liu R, Han X, Qi Z, Zhang X, He C, Han D, Yang YG, Kan Q.

Cell Res. 2018 May;28(5):597-600. doi: 10.1038/s41422-018-0014-x. Epub 2018 Feb 21. No abstract available.


Expression and therapeutic implications of cyclin-dependent kinase 4 (CDK4) in osteosarcoma.

Zhou Y, Shen JK, Yu Z, Hornicek FJ, Kan Q, Duan Z.

Biochim Biophys Acta. 2018 May;1864(5 Pt A):1573-1582. doi: 10.1016/j.bbadis.2018.02.004. Epub 2018 Feb 13.


Overexpression of Pyruvate dehydrogenase E1a subunit Inhibits Warburg effect and Induces Cell Apoptosis through Mitochondria-mediated Pathway in Hepatocellular Carcinoma.

Sun J, Li J, Guo Z, Sun L, Juan C, Zhou Y, Gu H, Yu Y, Hu Q, Kan Q, Yu Z.

Oncol Res. 2018 Feb 14. doi: 10.3727/096504018X15180451872087. [Epub ahead of print]


Curcumin induces apoptosis and inhibits proliferation in infantile hemangioma endothelial cells via downregulation of MCL-1 and HIF-1α.

Lou S, Wang Y, Yu Z, Guan K, Kan Q.

Medicine (Baltimore). 2018 Feb;97(7):e9562. doi: 10.1097/MD.0000000000009562.


Knockout of microRNA‑26a promotes lung development and pulmonary surfactant synthesis.

Sun YF, Kan Q, Yang Y, Zhang YH, Shen JX, Zhang C, Zhou XY.

Mol Med Rep. 2018 Apr;17(4):5988-5995. doi: 10.3892/mmr.2018.8602. Epub 2018 Feb 13.


[Observational study on the impact of corneal power on refractive status of patients after small incision lenticule extraction surgery].

Liu T, Yu T, Pan J, Zou YC, Liu LN, Kan QX, Bai J.

Zhonghua Yan Ke Za Zhi. 2018 Jan 11;54(1):48-54. doi: 10.3760/cma.j.issn.0412-4081.2018.01.009. Chinese.


Construction of an oesophageal cancer-specific ceRNA network based on miRNA, lncRNA, and mRNA expression data.

Xue WH, Fan ZR, Li LF, Lu JL, Ma BJ, Kan QC, Zhao J.

World J Gastroenterol. 2018 Jan 7;24(1):23-34. doi: 10.3748/wjg.v24.i1.23.


MicroRNA-335 is downregulated in papillary thyroid cancer and suppresses cancer cell growth, migration and invasion by directly targeting ZEB2.

Kan Q, Su Y, Yang H.

Oncol Lett. 2017 Dec;14(6):7622-7628. doi: 10.3892/ol.2017.7126. Epub 2017 Oct 3.


Response to 'Circumferential margin involvement after total mesorectal excision for mid or low rectal cancer: are all R1 resections equal?'

Wang JF, Kan QB.

Colorectal Dis. 2018 Apr;20(4):341. doi: 10.1111/codi.14015. No abstract available.


High-efficiency terahertz devices based on cross-polarization converter.

Zhao H, Wang X, He J, Guo J, Ye J, Kan Q, Zhang Y.

Sci Rep. 2017 Dec 20;7(1):17882. doi: 10.1038/s41598-017-18013-6.


Regulation of SIRT3/FOXO1 Signaling Pathway in Rats with Non-alcoholic Steatohepatitis by Salvianolic Acid B.

Wang Y, Chen J, Kong W, Zhu R, Liang K, Kan Q, Lou Y, Liu X.

Arch Med Res. 2017 Aug;48(6):506-512. doi: 10.1016/j.arcmed.2017.11.016. Epub 2017 Dec 7.


Tailoring axial intensity of laser beams with a heart-shaped hole.

Wang Y, Xie L, Ye J, Sun W, Wang X, Feng S, Han P, Kan Q, Zhang Y.

Opt Lett. 2017 Dec 1;42(23):4921-4924. doi: 10.1364/OL.42.004921.


Novel strategies to prevent the development of multidrug resistance (MDR) in cancer.

Wang J, Seebacher N, Shi H, Kan Q, Duan Z.

Oncotarget. 2017 Jul 12;8(48):84559-84571. doi: 10.18632/oncotarget.19187. eCollection 2017 Oct 13. Review.


Management of and risk factors for regional recurrence in upper lip squamous cell carcinoma.

Liu F, Wang L, Pang S, Kan Q.

Medicine (Baltimore). 2017 Nov;96(45):e8270. doi: 10.1097/MD.0000000000008270.


Blau syndrome with good Reponses to Tocilizumab: A case report and focused literature review.

Lu L, Shen M, Jiang D, Li Y, Zheng X, Li Y, Li Z, Zhang L, Tang J, Guo Y, Liu S, Zheng Z, Gao G, Kan Q.

Semin Arthritis Rheum. 2018 Apr;47(5):727-731. doi: 10.1016/j.semarthrit.2017.09.010. Epub 2017 Sep 25.


Topologically protected edge states in graphene plasmonic crystals.

Qiu P, Liang R, Qiu W, Chen H, Ren J, Lin Z, Wang JX, Kan Q, Pan JQ.

Opt Express. 2017 Sep 18;25(19):22587-22594. doi: 10.1364/OE.25.022587.


Histone Modifications Regulate the Developmental Expression of Human Hepatic UDP-Glucuronosyltransferase 1A1.

Nie YL, Meng XG, Liu JY, Yan L, Wang P, Bi HZ, Kan QC, Zhang LR.

Drug Metab Dispos. 2017 Dec;45(12):1372-1378. doi: 10.1124/dmd.117.076109. Epub 2017 Oct 12.


Prenatal Exposure to LPS Alters The Intrarenal RAS in Offspring, Which Is Ameliorated by Adipose Tissue-Derived Mesenchymal Stem Cells.

Ding XF, Sun M, Guan FX, Guo LN, Zhang YY, Wan YD, Zhang XJ, Yu YW, Ma SS, Yao HM, Yao R, Zhang RF, Sun TW, Kan QC.

Am J Hypertens. 2017 Nov 6;30(12):1211-1219. doi: 10.1093/ajh/hpx117.


MMP-9-cleaved osteopontin isoform mediates tumor immune escape by inducing expansion of myeloid-derived suppressor cells.

Shao L, Zhang B, Wang L, Wu L, Kan Q, Fan K.

Biochem Biophys Res Commun. 2017 Dec 2;493(4):1478-1484. doi: 10.1016/j.bbrc.2017.10.009. Epub 2017 Oct 4.


Regulation of microRNAs function by circular RNAs in human cancer.

Han C, Seebacher NA, Hornicek FJ, Kan Q, Duan Z.

Oncotarget. 2017 Aug 4;8(38):64622-64637. doi: 10.18632/oncotarget.19930. eCollection 2017 Sep 8. Review.


Integrated analysis profiles of long non-coding RNAs reveal potential biomarkers of drug resistance in lung cancer.

Xue W, Li L, Tian X, Fan Z, Yue Y, Zhang C, Ding X, Song X, Ma B, Zhai Y, Lu J, Kan Q, Zhao J.

Oncotarget. 2017 Mar 22;8(38):62868-62879. doi: 10.18632/oncotarget.16444. eCollection 2017 Sep 8.


Investigation of beam splitter in a zero-refractive-index photonic crystal at the frequency of Dirac-like point.

Qiu P, Qiu W, Lin Z, Chen H, Ren J, Wang JX, Kan Q, Pan JQ.

Sci Rep. 2017 Aug 29;7(1):9588. doi: 10.1038/s41598-017-10056-z.


The insufficient prognostic power of stenosis in patients with esophageal cancer.

Wang JF, Kan QB.

Int J Clin Oncol. 2017 Dec;22(6):1050-1051. doi: 10.1007/s10147-017-1186-y. Epub 2017 Aug 28. No abstract available.


Optimization of the Fano Resonance Lineshape Based on Graphene Plasmonic Hexamer in Mid-Infrared Frequencies.

Ren J, Wang G, Qiu W, Lin Z, Chen H, Qiu P, Wang JX, Kan Q, Pan JQ.

Nanomaterials (Basel). 2017 Aug 26;7(9). pii: E238. doi: 10.3390/nano7090238.


Reconstruction of full-thickness buccal defects with folded radial forearm flaps: A retrospective clinical study.

Liu F, Wang L, Pang S, Kan Q.

Medicine (Baltimore). 2017 Aug;96(32):e7344. doi: 10.1097/MD.0000000000007344.


Metabolic reprogramming is associated with flavopiridol resistance in prostate cancer DU145 cells.

Li X, Lu J, Kan Q, Li X, Fan Q, Li Y, Huang R, Slipicevic A, Dong HP, Eide L, Wang J, Zhang H, Berge V, Goscinski MA, Kvalheim G, Nesland JM, Suo Z.

Sci Rep. 2017 Jul 11;7(1):5081. doi: 10.1038/s41598-017-05086-6.


The Efficacy of Imrecoxib and Celecoxib in Axial Spondyloarthritis and Their Influence on Serum Dickopff-Related Protein 1 (DKK-1) Levels.

Gao GM, Li YM, Zheng XL, Jiang DB, Zhang LL, Xu PH, Liu SY, Zheng ZH, Kan QC.

Med Sci Monit. 2017 Jun 19;23:2985-2992.


Mitochondrial pyruvate carrier function determines cell stemness and metabolic reprogramming in cancer cells.

Li X, Han G, Li X, Kan Q, Fan Z, Li Y, Ji Y, Zhao J, Zhang M, Grigalavicius M, Berge V, Goscinski MA, Nesland JM, Suo Z.

Oncotarget. 2017 Jul 11;8(28):46363-46380. doi: 10.18632/oncotarget.18199.


Hybrid single-mode laser based on graphene Bragg gratings on silicon.

Ren Z, Kan Q, Ran G, Jin C, Yuan L, Wang X, Tao L, Yu H, Zhang L, Chen W, He K, Ma RM, Pan J, Wang W.

Opt Lett. 2017 Jun 1;42(11):2134-2137. doi: 10.1364/OL.42.002134.


Dynamically Tunable Plasmon-Induced Transparency in On-chip Graphene-Based Asymmetrical Nanocavity-Coupled Waveguide System.

Qiu P, Qiu W, Lin Z, Chen H, Ren J, Wang JX, Kan Q, Pan JQ.

Nanoscale Res Lett. 2017 Dec;12(1):374. doi: 10.1186/s11671-017-2148-z. Epub 2017 May 25.


Alterations of Histone Modifications Contribute to Pregnane X Receptor-Mediated Induction of CYP3A4 by Rifampicin.

Yan L, Wang Y, Liu J, Nie Y, Zhong XB, Kan Q, Zhang L.

Mol Pharmacol. 2017 Aug;92(2):113-123. doi: 10.1124/mol.117.108225. Epub 2017 May 25.

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