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31 P magnetic resonance spectroscopy in skeletal muscle: Experts' consensus recommendations.

Meyerspeer M, Boesch C, Cameron D, Dezortová M, Forbes SC, Heerschap A, Jeneson JAL, Kan HE, Kent J, Layec G, Prompers JJ, Reyngoudt H, Sleigh A, Valkovič L, Kemp GJ; Experts' Working Group on 31P MR Spectroscopy of Skeletal Muscle.

NMR Biomed. 2020 Feb 10:e4246. doi: 10.1002/nbm.4246. [Epub ahead of print]


The anti-diabetic effect of eight Lagerstroemia speciosa leaf extracts based on the contents of ellagitannins and ellagic acid derivatives.

Guo S, Ren X, He K, Chen X, Zhang S, Roller M, Zheng B, Zheng Q, Ho CT, Bai N.

Food Funct. 2020 Jan 31. doi: 10.1039/c9fo03091c. [Epub ahead of print]


Human Brown Adipose Tissue Estimated With Magnetic Resonance Imaging Undergoes Changes in Composition After Cold Exposure: An in vivo MRI Study in Healthy Volunteers.

Abreu-Vieira G, Sardjoe Mishre ASD, Burakiewicz J, Janssen LGM, Nahon KJ, van der Eijk JA, Riem TT, Boon MR, Dzyubachyk O, Webb AG, Rensen PCN, Kan HE.

Front Endocrinol (Lausanne). 2020 Jan 9;10:898. doi: 10.3389/fendo.2019.00898. eCollection 2019.


Twelve weeks of exenatide treatment increases [18F]fluorodeoxyglucose uptake by brown adipose tissue without affecting oxidative resting energy expenditure in nondiabetic males.

Janssen LGM, Nahon KJ, Bracké KFM, van den Broek D, Smit R, Sardjoe Mishre ASD, Koorneef LL, Martinez-Tellez B, Burakiewicz J, Kan HE, van Velden FHP, Pereira Arias-Bouda LM, de Geus-Oei LF, Berbée JFP, Jazet IM, Boon MR, Rensen PCN.

Metabolism. 2020 Jan 23:154167. doi: 10.1016/j.metabol.2020.154167. [Epub ahead of print]


MRI vastus lateralis fat fraction predicts loss of ambulation in Duchenne muscular dystrophy.

Naarding KJ, Reyngoudt H, van Zwet EW, Hooijmans MT, Tian C, Rybalsky I, Shellenbarger KC, Le Louër J, Wong BL, Carlier PG, Kan HE, Niks EH.

Neurology. 2020 Jan 14. pii: 10.1212/WNL.0000000000008939. doi: 10.1212/WNL.0000000000008939. [Epub ahead of print]


Advanced single voxel 1 H magnetic resonance spectroscopy techniques in humans: Experts' consensus recommendations.

Öz G, Deelchand DK, Wijnen JP, Mlynárik V, Xin L, Mekle R, Noeske R, Scheenen TWJ, Tkáč I; Experts' Working Group on Advanced Single Voxel 1H MRS.

NMR Biomed. 2020 Jan 10:e4236. doi: 10.1002/nbm.4236. [Epub ahead of print]


Water-fat separation in spiral magnetic resonance fingerprinting for high temporal resolution tissue relaxation time quantification in muscle.

Koolstra K, Webb AG, Veeger TTJ, Kan HE, Koken P, Börnert P.

Magn Reson Med. 2020 Jan 3. doi: 10.1002/mrm.28143. [Epub ahead of print]


1,3-Dicaffeoylquinic acid targeting 14-3-3 tau suppresses human breast cancer cell proliferation and metastasis through IL6/JAK2/PI3K pathway.

Zhou Y, Fu X, Guan Y, Gong M, He K, Huang B.

Biochem Pharmacol. 2020 Feb;172:113752. doi: 10.1016/j.bcp.2019.113752. Epub 2019 Dec 11.


A transcriptomic analysis of Nsmce1 overexpression in mouse hippocampal neuronal cell by RNA sequencing.

Gong M, Wang Z, Liu Y, Li W, Ye S, Zhu J, Zhang H, Wang J, He K.

Funct Integr Genomics. 2019 Dec 2. doi: 10.1007/s10142-019-00728-6. [Epub ahead of print]


A transcriptomic study of selenium against liver injury induced by beta-cypermethrin in mice by RNA-seq.

He K, Tang Q, Gong M, Yang S, Chen X, Zhu H, Liu D, Huang B.

Funct Integr Genomics. 2019 Oct 28. doi: 10.1007/s10142-019-00719-7. [Epub ahead of print]


Janus nanocarrier-based co-delivery of doxorubicin and berberine weakens chemotherapy-exacerbated hepatocellular carcinoma recurrence.

Zhang F, Jia Y, Zheng X, Shao D, Zhao Y, Wang Z, Dawulieti J, Liu W, Sun M, Sun W, Pan Y, Cui L, Wang Y, He K, Zhang M, Li J, Dong WF, Chen L.

Acta Biomater. 2019 Dec;100:352-364. doi: 10.1016/j.actbio.2019.09.034. Epub 2019 Sep 26.


5-FU preferably induces apoptosis in BRAF V600E colorectal cancer cells via downregulation of Bcl-xL.

Shi T, Gao M, He M, Yue F, Zhao Y, Sun M, He K, Chen L.

Mol Cell Biochem. 2019 Nov;461(1-2):151-158. doi: 10.1007/s11010-019-03598-5. Epub 2019 Jul 27.


Multi-center evaluation of stability and reproducibility of quantitative MRI measures in healthy calf muscles.

Schlaffke L, Rehmann R, Rohm M, Otto LAM, de Luca A, Burakiewicz J, Baligand C, Monte J, den Harder C, Hooijmans MT, Nederveen A, Schlaeger S, Weidlich D, Karampinos DC, Stouge A, Vaeggemose M, D'Angelo MG, Arrigoni F, Kan HE, Froeling M.

NMR Biomed. 2019 Sep;32(9):e4119. doi: 10.1002/nbm.4119. Epub 2019 Jul 17.


Accurate colorectal tumor segmentation for CT scans based on the label assignment generative adversarial network.

Liu X, Guo S, Zhang H, He K, Mu S, Guo Y, Li X.

Med Phys. 2019 Aug;46(8):3532-3542. doi: 10.1002/mp.13584. Epub 2019 Jun 25.


Regulatory network reconstruction of five essential microRNAs for survival analysis in breast cancer by integrating miRNA and mRNA expression datasets.

He K, Li WX, Guan D, Gong M, Ye S, Fang Z, Huang JF, Lu A.

Funct Integr Genomics. 2019 Jul;19(4):645-658. doi: 10.1007/s10142-019-00670-7. Epub 2019 Mar 12.


Entanglement criterion independent on observables for multipartite Gaussian states based on uncertainty principle.

He K, Huang M, Hou J.

Sci Rep. 2019 Feb 4;9(1):1314. doi: 10.1038/s41598-018-36307-1.


Depression Promotes Hepatocellular Carcinoma Progression through a Glucocorticoids Mediated Up-Regulation of PD-1 Expression in Tumor infiltrating NK Cells.

Zhao Y, Jia Y, Shi T, Wang W, Shao D, Zheng X, Sun M, He K, Chen L.

Carcinogenesis. 2019 Feb 4. doi: 10.1093/carcin/bgz017. [Epub ahead of print]


Exploration of New Contrasts, Targets, and MR Imaging and Spectroscopy Techniques for Neuromuscular Disease - A Workshop Report of Working Group 3 of the Biomedicine and Molecular Biosciences COST Action BM1304 MYO-MRI.

Strijkers GJ, Araujo ECA, Azzabou N, Bendahan D, Blamire A, Burakiewicz J, Carlier PG, Damon B, Deligianni X, Froeling M, Heerschap A, Hollingsworth KG, Hooijmans MT, Karampinos DC, Loudos G, Madelin G, Marty B, Nagel AM, Nederveen AJ, Nelissen JL, Santini F, Scheidegger O, Schick F, Sinclair C, Sinkus R, de Sousa PL, Straub V, Walter G, Kan HE.

J Neuromuscul Dis. 2019;6(1):1-30. doi: 10.3233/JND-180333.


Comprehensive analysis of gene expression profiles associated with proliferative diabetic retinopathy.

Gong MT, Li WX, Zhang Q, Lv WW, He ZH, Zhou SL, Zhang H, Wang J, He K.

Exp Ther Med. 2018 Oct;16(4):3539-3545. doi: 10.3892/etm.2018.6635. Epub 2018 Aug 21.


Comprehensive integrated analysis of gene expression datasets identifies key anti-cancer targets in different stages of breast cancer.

Gong MT, Ye SD, Lv WW, He K, Li WX.

Exp Ther Med. 2018 Aug;16(2):802-810. doi: 10.3892/etm.2018.6268. Epub 2018 Jun 7.


Self-assembled dual fluorescence nanoparticles for CD44-targeted delivery of anti-miR-27a in liver cancer theranostics.

Zheng X, Zhang F, Zhao Y, Zhang J, Dawulieti J, Pan Y, Cui L, Sun M, Shao D, Li M, He K, Zhang M, Li J, Chen L.

Theranostics. 2018 Jun 13;8(14):3808-3823. doi: 10.7150/thno.25255. eCollection 2018.


Report on the workshop: Meaningful outcome measures for Duchenne muscular dystrophy, London, UK, 30-31 January 2017.

Straub V, Mercuri E; DMD outcome measure study group.

Neuromuscul Disord. 2018 Aug;28(8):690-701. doi: 10.1016/j.nmd.2018.05.013. Epub 2018 Jun 6. No abstract available.


Chemical Investigation of Major Constituents in Aloe vera Leaves and Several Commercial Aloe Juice Powders.

Zhang Y, Bao Z, Ye X, Xie Z, He K, Mergens B, Li W, Yatcilla M, Zheng Q.

J AOAC Int. 2018 Nov 1;101(6):1741-1751. doi: 10.5740/jaoacint.18-0122. Epub 2018 Jun 28.


Molecular Weight Determination of Aloe Polysaccharides Using Size Exclusion Chromatography Coupled with Multi-Angle Laser Light Scattering and Refractive Index Detectors.

He K, Mergens B, Yatcilla M, Zheng Q, Bao Z, Zhang Y, Li X, Xie Z.

J AOAC Int. 2018 Nov 1;101(6):1729-1740. doi: 10.5740/jaoacint.18-0121. Epub 2018 Jun 28.


Obesity-associated miR-27a upregulation promotes hepatocellular carcinoma metastasis through suppressing SFRP1.

Chen Y, Zhang F, Zhao Y, He K, Zheng X, Pan Y, Shao D, Shang P, Yang Y, Zhang D, Xie Y, Yao X, Chen L, Li J, Zhang X.

Onco Targets Ther. 2018 Jun 1;11:3281-3292. doi: 10.2147/OTT.S162978. eCollection 2018.


Aloe vera: Chemistry, Major Chemical Components, Quantification, and Molecular Weight Determination of Polysaccharides.

He K.

J AOAC Int. 2018 Nov 1;101(6):1709-1710. doi: 10.5740/jaoacint.18-0118. Epub 2018 Jun 12. No abstract available.


Tracking disease progression non-invasively in Duchenne and Becker muscular dystrophies.

Spitali P, Hettne K, Tsonaka R, Charrout M, van den Bergen J, Koeks Z, Kan HE, Hooijmans MT, Roos A, Straub V, Muntoni F, Al-Khalili-Szigyarto C, Koel-Simmelink MJA, Teunissen CE, Lochmüller H, Niks EH, Aartsma-Rus A.

J Cachexia Sarcopenia Muscle. 2018 Aug;9(4):715-726. doi: 10.1002/jcsm.12304. Epub 2018 Apr 16.


Author Correction: Timing and localization of human dystrophin isoform expression provide insights into the cognitive phenotype of Duchenne muscular dystrophy.

Doorenweerd N, Mahfouz A, van Putten M, Kaliyaperumal R, T' Hoen PAC, Hendriksen JGM, Aartsma-Rus AM, Verschuuren JJGM, Niks EH, Reinders MJT, Kan HE, Lelieveldt BPF.

Sci Rep. 2018 Mar 1;8(1):4058. doi: 10.1038/s41598-018-22154-7.


Chemotherapy induces ovarian cancer cell repopulation through the caspase 3-mediated arachidonic acid metabolic pathway.

Cui L, Zhao Y, Pan Y, Zheng X, Shao D, Jia Y, He K, Li K, Chen L.

Onco Targets Ther. 2017 Dec 8;10:5817-5826. doi: 10.2147/OTT.S150456. eCollection 2017.


Shape-controlled magnetic mesoporous silica nanoparticles for magnetically-mediated suicide gene therapy of hepatocellular carcinoma.

Wang Z, Chang Z, Lu M, Shao D, Yue J, Yang D, Zheng X, Li M, He K, Zhang M, Chen L, Dong WF.

Biomaterials. 2018 Feb;154:147-157. doi: 10.1016/j.biomaterials.2017.10.047. Epub 2017 Nov 4.


A transcriptomic study of myogenic differentiation under the overexpression of PPARγ by RNA-Seq.

He K, Wu G, Li WX, Guan D, Lv W, Gong M, Ye S, Lu A.

Sci Rep. 2017 Nov 10;7(1):15308. doi: 10.1038/s41598-017-14275-2.


Berberine inhibits the chemotherapy-induced repopulation by suppressing the arachidonic acid metabolic pathway and phosphorylation of FAK in ovarian cancer.

Zhao Y, Cui L, Pan Y, Shao D, Zheng X, Zhang F, Zhang H, He K, Chen L.

Cell Prolif. 2017 Dec;50(6). doi: 10.1111/cpr.12393. Epub 2017 Oct 8.


Timing and localization of human dystrophin isoform expression provide insights into the cognitive phenotype of Duchenne muscular dystrophy.

Doorenweerd N, Mahfouz A, van Putten M, Kaliyaperumal R, T' Hoen PAC, Hendriksen JGM, Aartsma-Rus AM, Verschuuren JJGM, Niks EH, Reinders MJT, Kan HE, Lelieveldt BPF.

Sci Rep. 2017 Oct 3;7(1):12575. doi: 10.1038/s41598-017-12981-5. Erratum in: Sci Rep. 2018 Mar 1;8(1):4058.


Validation of a pharmacological model for mitochondrial dysfunction in healthy subjects using simvastatin: A randomized placebo-controlled proof-of-pharmacology study.

van Diemen MPJ, Berends CL, Akram N, Wezel J, Teeuwisse WM, Mik BG, Kan HE, Webb A, Beenakker JWM, Groeneveld GJ.

Eur J Pharmacol. 2017 Nov 15;815:290-297. doi: 10.1016/j.ejphar.2017.09.031. Epub 2017 Sep 21.


A novel mutation in the hepatocyte nuclear factor-1β gene in maturity onset diabetes of the young 5 with multiple renal cysts and pancreas hypogenesis: A case report.

Lv Y, Li Z, He K, Gao Y, Xiao X, Liu Y, Wang G.

Exp Ther Med. 2017 Oct;14(4):3131-3136. doi: 10.3892/etm.2017.4871. Epub 2017 Aug 2.


Berberine Enhances Chemosensitivity and Induces Apoptosis Through Dose-orchestrated AMPK Signaling in Breast Cancer.

Pan Y, Zhang F, Zhao Y, Shao D, Zheng X, Chen Y, He K, Li J, Chen L.

J Cancer. 2017 Jun 5;8(9):1679-1689. doi: 10.7150/jca.19106. eCollection 2017.


Spatially localized phosphorous metabolism of skeletal muscle in Duchenne muscular dystrophy patients: 24-month follow-up.

Hooijmans MT, Doorenweerd N, Baligand C, Verschuuren JJGM, Ronen I, Niks EH, Webb AG, Kan HE.

PLoS One. 2017 Aug 1;12(8):e0182086. doi: 10.1371/journal.pone.0182086. eCollection 2017.


Qualitative and quantitative analysis of chemical constituents of Ptychopetalum olacoides Benth.

Tian X, Guo S, He K, Roller M, Yang M, Liu Q, Zhang L, Ho CT, Bai N.

Nat Prod Res. 2018 Feb;32(3):354-357. doi: 10.1080/14786419.2017.1354187. Epub 2017 Jul 27.


Quantifying fat replacement of muscle by quantitative MRI in muscular dystrophy.

Burakiewicz J, Sinclair CDJ, Fischer D, Walter GA, Kan HE, Hollingsworth KG.

J Neurol. 2017 Oct;264(10):2053-2067. doi: 10.1007/s00415-017-8547-3. Epub 2017 Jul 1. Review.


Berberine Reverses Hypoxia-induced Chemoresistance in Breast Cancer through the Inhibition of AMPK- HIF-1α.

Pan Y, Shao D, Zhao Y, Zhang F, Zheng X, Tan Y, He K, Li J, Chen L.

Int J Biol Sci. 2017 Jun 1;13(6):794-803. doi: 10.7150/ijbs.18969. eCollection 2017.


Cortical glutamate in migraine.

Zielman R, Wijnen JP, Webb A, Onderwater GLJ, Ronen I, Ferrari MD, Kan HE, Terwindt GM, Kruit MC.

Brain. 2017 Jul 1;140(7):1859-1871. doi: 10.1093/brain/awx130.


Correction to Evaluating the Role of Multidrug Resistance Protein 3 (MDR3) Inhibition in Predicting Drug-Induced Liver Injury Using 125 Pharmaceuticals.

Aleo MD, Shah F, He K, Bonin PD, Rodrigues AD.

Chem Res Toxicol. 2017 Jun 19;30(6):1365. doi: 10.1021/acs.chemrestox.7b00124. Epub 2017 May 18. No abstract available.


Evaluating the Role of Multidrug Resistance Protein 3 (MDR3) Inhibition in Predicting Drug-Induced Liver Injury Using 125 Pharmaceuticals.

Aleo MD, Shah F, He K, Bonin PD, Rodrigues AD.

Chem Res Toxicol. 2017 May 15;30(5):1219-1229. doi: 10.1021/acs.chemrestox.7b00048. Epub 2017 May 4. Erratum in: Chem Res Toxicol. 2017 Jun 19;30(6):1365.


In Vitro Drug-Induced Liver Injury Prediction: Criteria Optimization of Efflux Transporter IC50 and Physicochemical Properties.

Yucha RW, He K, Shi Q, Cai L, Nakashita Y, Xia CQ, Liao M.

Toxicol Sci. 2017 Jun 1;157(2):487-499. doi: 10.1093/toxsci/kfx060.


Non-uniform muscle fat replacement along the proximodistal axis in Duchenne muscular dystrophy.

Hooijmans MT, Niks EH, Burakiewicz J, Anastasopoulos C, van den Berg SI, van Zwet E, Webb AG, Verschuuren JJGM, Kan HE.

Neuromuscul Disord. 2017 May;27(5):458-464. doi: 10.1016/j.nmd.2017.02.009. Epub 2017 Feb 21.


Depletion of Tcf3 and Lef1 maintains mouse embryonic stem cell self-renewal.

Ye S, Zhang T, Tong C, Zhou X, He K, Ban Q, Liu D, Ying QL.

Biol Open. 2017 Apr 15;6(4):511-517. doi: 10.1242/bio.022426.


Proton Magnetic Resonance Spectroscopy Indicates Preserved Cerebral Biochemical Composition in Duchenne Muscular Dystrophy Patients.

Doorenweerd N, Hooijmans M, Schubert SA, Webb AG, Straathof CS, van Zwet EW, van Buchem MA, Verschuuren JJ, Hendriksen JG, Niks EH, Kan HE.

J Neuromuscul Dis. 2017;4(1):53-58. doi: 10.3233/JND-160201.


Improved olefinic fat suppression in skeletal muscle DTI using a magnitude-based dixon method.

Burakiewicz J, Hooijmans MT, Webb AG, Verschuuren JJGM, Niks EH, Kan HE.

Magn Reson Med. 2018 Jan;79(1):152-159. doi: 10.1002/mrm.26655. Epub 2017 Mar 5.


Comprehensive tissue-specific gene set enrichment analysis and transcription factor analysis of breast cancer by integrating 14 gene expression datasets.

Li WX, He K, Tang L, Dai SX, Li GH, Lv WW, Guo YC, An SQ, Wu GY, Liu D, Huang JF.

Oncotarget. 2017 Jan 24;8(4):6775-6786. doi: 10.18632/oncotarget.14286.

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