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Items: 1 to 50 of 75

1.

Sequencing Library Preparation from Degraded Samples for Non-illumina Sequencing Platforms.

Martins RF, Kampmann ML, Förster DW.

Methods Mol Biol. 2019;1963:85-92. doi: 10.1007/978-1-4939-9176-1_10.

PMID:
30875047
2.

Probing the Global Cellular Responses to Lipotoxicity Caused by Saturated Fatty Acids.

Piccolis M, Bond LM, Kampmann M, Pulimeno P, Chitraju C, Jayson CBK, Vaites LP, Boland S, Lai ZW, Gabriel KR, Elliott SD, Paulo JA, Harper JW, Weissman JS, Walther TC, Farese RV Jr.

Mol Cell. 2019 Feb 26. pii: S1097-2765(19)30056-5. doi: 10.1016/j.molcel.2019.01.036. [Epub ahead of print]

PMID:
30846318
3.

Heterochromatin anomalies and double-stranded RNA accumulation underlie C9orf72 poly(PR) toxicity.

Zhang YJ, Guo L, Gonzales PK, Gendron TF, Wu Y, Jansen-West K, O'Raw AD, Pickles SR, Prudencio M, Carlomagno Y, Gachechiladze MA, Ludwig C, Tian R, Chew J, DeTure M, Lin WL, Tong J, Daughrity LM, Yue M, Song Y, Andersen JW, Castanedes-Casey M, Kurti A, Datta A, Antognetti G, McCampbell A, Rademakers R, Oskarsson B, Dickson DW, Kampmann M, Ward ME, Fryer JD, Link CD, Shorter J, Petrucelli L.

Science. 2019 Feb 15;363(6428). pii: eaav2606. doi: 10.1126/science.aav2606.

PMID:
30765536
4.

Relapse-associated AURKB blunts the glucocorticoid sensitivity of B cell acute lymphoblastic leukemia.

Poulard C, Kim HN, Fang M, Kruth K, Gagnieux C, Gerke DS, Bhojwani D, Kim YM, Kampmann M, Stallcup MR, Pufall MA.

Proc Natl Acad Sci U S A. 2019 Feb 19;116(8):3052-3061. doi: 10.1073/pnas.1816254116. Epub 2019 Feb 7.

PMID:
30733284
5.

A high-throughput screen of real-time ATP levels in individual cells reveals mechanisms of energy failure.

Mendelsohn BA, Bennett NK, Darch MA, Yu K, Nguyen MK, Pucciarelli D, Nelson M, Horlbeck MA, Gilbert LA, Hyun W, Kampmann M, Nakamura JL, Nakamura K.

PLoS Biol. 2018 Aug 27;16(8):e2004624. doi: 10.1371/journal.pbio.2004624. eCollection 2018 Aug.

6.

CRISPR-based genetic interaction maps inform therapeutic strategies in cancer.

Ramkumar P, Kampmann M.

Transl Cancer Res. 2018 Feb;7(Suppl 1):S61-S67. doi: 10.21037/tcr.2018.01.02. No abstract available.

7.

The Psychiatric Cell Map Initiative: A Convergent Systems Biological Approach to Illuminating Key Molecular Pathways in Neuropsychiatric Disorders.

Willsey AJ, Morris MT, Wang S, Willsey HR, Sun N, Teerikorpi N, Baum TB, Cagney G, Bender KJ, Desai TA, Srivastava D, Davis GW, Doudna J, Chang E, Sohal V, Lowenstein DH, Li H, Agard D, Keiser MJ, Shoichet B, von Zastrow M, Mucke L, Finkbeiner S, Gan L, Sestan N, Ward ME, Huttenhain R, Nowakowski TJ, Bellen HJ, Frank LM, Khokha MK, Lifton RP, Kampmann M, Ideker T, State MW, Krogan NJ.

Cell. 2018 Jul 26;174(3):505-520. doi: 10.1016/j.cell.2018.06.016. Review.

PMID:
30053424
8.

Extending chemical perturbations of the ubiquitin fitness landscape in a classroom setting reveals new constraints on sequence tolerance.

Mavor D, Barlow KA, Asarnow D, Birman Y, Britain D, Chen W, Green EM, Kenner LR, Mensa B, Morinishi LS, Nelson CA, Poss EM, Suresh P, Tian R, Arhar T, Ary BE, Bauer DP, Bergman ID, Brunetti RM, Chio CM, Dai SA, Dickinson MS, Elledge SK, Helsell CVM, Hendel NL, Kang E, Kern N, Khoroshkin MS, Kirkemo LL, Lewis GR, Lou K, Marin WM, Maxwell AM, McTigue PF, Myers-Turnbull D, Nagy TL, Natale AM, Oltion K, Pourmal S, Reder GK, Rettko NJ, Rohweder PJ, Schwarz DMC, Tan SK, Thomas PV, Tibble RW, Town JP, Tsai MK, Ugur FS, Wassarman DR, Wolff AM, Wu TS, Bogdanoff D, Li J, Thorn KS, O'Conchúir S, Swaney DL, Chow ED, Madhani HD, Redding S, Bolon DN, Kortemme T, DeRisi JL, Kampmann M, Fraser JS.

Biol Open. 2018 Jul 23;7(7). pii: bio036103. doi: 10.1242/bio.036103.

9.

Mapping the Genetic Landscape of Human Cells.

Horlbeck MA, Xu A, Wang M, Bennett NK, Park CY, Bogdanoff D, Adamson B, Chow ED, Kampmann M, Peterson TR, Nakamura K, Fischbach MA, Weissman JS, Gilbert LA.

Cell. 2018 Aug 9;174(4):953-967.e22. doi: 10.1016/j.cell.2018.06.010. Epub 2018 Jul 19.

PMID:
30033366
10.

Unilateral leg oedema due to spontaneous Achilles tendon rupture.

Papadopoulou A, Kronlage C, Kampmann M, Budweg J.

Oxf Med Case Reports. 2018 Jun 1;2018(6):omy022. doi: 10.1093/omcr/omy022. eCollection 2018 Jun.

11.

Tau Internalization is Regulated by 6-O Sulfation on Heparan Sulfate Proteoglycans (HSPGs).

Rauch JN, Chen JJ, Sorum AW, Miller GM, Sharf T, See SK, Hsieh-Wilson LC, Kampmann M, Kosik KS.

Sci Rep. 2018 Apr 23;8(1):6382. doi: 10.1038/s41598-018-24904-z.

12.

Human Apolipoprotein A1 at Solid/Liquid and Liquid/Gas Interfaces.

Dogan S, Paulus M, Forov Y, Weis C, Kampmann M, Cewe C, Kiesel I, Degen P, Salmen P, Rehage H, Tolan M.

J Phys Chem B. 2018 Apr 12;122(14):3953-3960. doi: 10.1021/acs.jpcb.7b12481. Epub 2018 Mar 28.

PMID:
29488751
13.

Body fluid identification using a targeted mRNA massively parallel sequencing approach - results of a EUROFORGEN/EDNAP collaborative exercise.

Ingold S, Dørum G, Hanson E, Berti A, Branicki W, Brito P, Elsmore P, Gettings KB, Giangasparo F, Gross TE, Hansen S, Hanssen EN, Kampmann ML, Kayser M, Laurent FX, Morling N, Mosquera-Miguel A, Parson W, Phillips C, Porto MJ, Pośpiech E, Roeder AD, Schneider PM, Schulze Johann K, Steffen CR, Syndercombe-Court D, Trautmann M, van den Berge M, van der Gaag KJ, Vannier J, Verdoliva V, Vidaki A, Xavier C, Ballantyne J, Haas C.

Forensic Sci Int Genet. 2018 May;34:105-115. doi: 10.1016/j.fsigen.2018.01.002. Epub 2018 Jan 31.

PMID:
29453107
14.

Quantification of massively parallel sequencing libraries - a comparative study of eight methods.

Hussing C, Kampmann ML, Mogensen HS, Børsting C, Morling N.

Sci Rep. 2018 Jan 18;8(1):1110. doi: 10.1038/s41598-018-19574-w.

15.

Dual gene activation and knockout screen reveals directional dependencies in genetic networks.

Boettcher M, Tian R, Blau JA, Markegard E, Wagner RT, Wu D, Mo X, Biton A, Zaitlen N, Fu H, McCormick F, Kampmann M, McManus MT.

Nat Biotechnol. 2018 Feb;36(2):170-178. doi: 10.1038/nbt.4062. Epub 2018 Jan 15.

16.

CRISPRi and CRISPRa Screens in Mammalian Cells for Precision Biology and Medicine.

Kampmann M.

ACS Chem Biol. 2018 Feb 16;13(2):406-416. doi: 10.1021/acschembio.7b00657. Epub 2017 Oct 24. Review.

17.

Combined CRISPRi/a-Based Chemical Genetic Screens Reveal that Rigosertib Is a Microtubule-Destabilizing Agent.

Jost M, Chen Y, Gilbert LA, Horlbeck MA, Krenning L, Menchon G, Rai A, Cho MY, Stern JJ, Prota AE, Kampmann M, Akhmanova A, Steinmetz MO, Tanenbaum ME, Weissman JS.

Mol Cell. 2017 Oct 5;68(1):210-223.e6. doi: 10.1016/j.molcel.2017.09.012.

18.

Comparison of manual and automated AmpliSeq™ workflows in the typing of a Somali population with the Precision ID Identity Panel.

van der Heijden S, de Oliveira SJ, Kampmann ML, Børsting C, Morling N.

Forensic Sci Int Genet. 2017 Nov;31:118-125. doi: 10.1016/j.fsigen.2017.09.009. Epub 2017 Sep 14.

PMID:
28938152
19.

CRISPulator: a discrete simulation tool for pooled genetic screens.

Nagy T, Kampmann M.

BMC Bioinformatics. 2017 Jul 21;18(1):347. doi: 10.1186/s12859-017-1759-9.

20.

Elucidating drug targets and mechanisms of action by genetic screens in mammalian cells.

Kampmann M.

Chem Commun (Camb). 2017 Jun 29;53(53):7162-7167. doi: 10.1039/c7cc02349a. Review.

21.

A CRISPR Approach to Neurodegenerative Diseases.

Kampmann M.

Trends Mol Med. 2017 Jun;23(6):483-485. doi: 10.1016/j.molmed.2017.04.003. Epub 2017 May 4.

22.

Suppression of B-cell development genes is key to glucocorticoid efficacy in treatment of acute lymphoblastic leukemia.

Kruth KA, Fang M, Shelton DN, Abu-Halawa O, Mahling R, Yang H, Weissman JS, Loh ML, Müschen M, Tasian SK, Bassik MC, Kampmann M, Pufall MA.

Blood. 2017 Jun 1;129(22):3000-3008. doi: 10.1182/blood-2017-02-766204. Epub 2017 Apr 19.

23.

The mTOR Complex Controls HIV Latency.

Besnard E, Hakre S, Kampmann M, Lim HW, Hosmane NN, Martin A, Bassik MC, Verschueren E, Battivelli E, Chan J, Svensson JP, Gramatica A, Conrad RJ, Ott M, Greene WC, Krogan NJ, Siliciano RF, Weissman JS, Verdin E.

Cell Host Microbe. 2016 Dec 14;20(6):785-797. doi: 10.1016/j.chom.2016.11.001.

24.

ISO 17025 validation of a next-generation sequencing assay for relationship testing.

Buchard A, Kampmann ML, Poulsen L, Børsting C, Morling N.

Electrophoresis. 2016 Oct;37(21):2822-2831. doi: 10.1002/elps.201600269. Epub 2016 Oct 6.

PMID:
27709635
25.

Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation.

Horlbeck MA, Gilbert LA, Villalta JE, Adamson B, Pak RA, Chen Y, Fields AP, Park CY, Corn JE, Kampmann M, Weissman JS.

Elife. 2016 Sep 23;5. pii: e19760. doi: 10.7554/eLife.19760.

26.

High-throughput sequencing of forensic genetic samples using punches of FTA cards with buccal swabs.

Kampmann ML, Buchard A, Børsting C, Morling N.

Biotechniques. 2016 Sep 1;61(3):149-51. doi: 10.2144/000114453. eCollection 2016.

27.

Parallel shRNA and CRISPR-Cas9 screens enable antiviral drug target identification.

Deans RM, Morgens DW, Ökesli A, Pillay S, Horlbeck MA, Kampmann M, Gilbert LA, Li A, Mateo R, Smith M, Glenn JS, Carette JE, Khosla C, Bassik MC.

Nat Chem Biol. 2016 May;12(5):361-6. doi: 10.1038/nchembio.2050. Epub 2016 Mar 28.

28.

Targeting the AAA ATPase p97 as an Approach to Treat Cancer through Disruption of Protein Homeostasis.

Anderson DJ, Le Moigne R, Djakovic S, Kumar B, Rice J, Wong S, Wang J, Yao B, Valle E, Kiss von Soly S, Madriaga A, Soriano F, Menon MK, Wu ZY, Kampmann M, Chen Y, Weissman JS, Aftab BT, Yakes FM, Shawver L, Zhou HJ, Wustrow D, Rolfe M.

Cancer Cell. 2015 Nov 9;28(5):653-665. doi: 10.1016/j.ccell.2015.10.002.

29.

Paradoxical resistance of multiple myeloma to proteasome inhibitors by decreased levels of 19S proteasomal subunits.

Acosta-Alvear D, Cho MY, Wild T, Buchholz TJ, Lerner AG, Simakova O, Hahn J, Korde N, Landgren O, Maric I, Choudhary C, Walter P, Weissman JS, Kampmann M.

Elife. 2015 Sep 1;4:e08153. doi: 10.7554/eLife.08153.

30.

Next-generation libraries for robust RNA interference-based genome-wide screens.

Kampmann M, Horlbeck MA, Chen Y, Tsai JC, Bassik MC, Gilbert LA, Villalta JE, Kwon SC, Chang H, Kim VN, Weissman JS.

Proc Natl Acad Sci U S A. 2015 Jun 30;112(26):E3384-91. doi: 10.1073/pnas.1508821112. Epub 2015 Jun 15.

31.

Pharmacological dimerization and activation of the exchange factor eIF2B antagonizes the integrated stress response.

Sidrauski C, Tsai JC, Kampmann M, Hearn BR, Vedantham P, Jaishankar P, Sokabe M, Mendez AS, Newton BW, Tang EL, Verschueren E, Johnson JR, Krogan NJ, Fraser CS, Weissman JS, Renslo AR, Walter P.

Elife. 2015 Apr 15;4:e07314. doi: 10.7554/eLife.07314.

32.

Corrigendum: functional genomics platform for pooled screening and generation of mammalian genetic interaction maps.

Kampmann M, Bassik MC, Weissman JS.

Nat Protoc. 2015 Apr;10(4):643. doi: 10.1038/nprot0415-644d. Epub 2015 Mar 26. No abstract available.

PMID:
25811902
33.

Validation of the Hsp70-Bag3 protein-protein interaction as a potential therapeutic target in cancer.

Li X, Colvin T, Rauch JN, Acosta-Alvear D, Kampmann M, Dunyak B, Hann B, Aftab BT, Murnane M, Cho M, Walter P, Weissman JS, Sherman MY, Gestwicki JE.

Mol Cancer Ther. 2015 Mar;14(3):642-8. doi: 10.1158/1535-7163.MCT-14-0650. Epub 2015 Jan 6.

34.

Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation.

Gilbert LA, Horlbeck MA, Adamson B, Villalta JE, Chen Y, Whitehead EH, Guimaraes C, Panning B, Ploegh HL, Bassik MC, Qi LS, Kampmann M, Weissman JS.

Cell. 2014 Oct 23;159(3):647-61. doi: 10.1016/j.cell.2014.09.029. Epub 2014 Oct 9.

35.

Hybridization capture using short PCR products enriches small genomes by capturing flanking sequences (CapFlank).

Tsangaras K, Wales N, Sicheritz-Pontén T, Rasmussen S, Michaux J, Ishida Y, Morand S, Kampmann ML, Gilbert MT, Greenwood AD.

PLoS One. 2014 Oct 2;9(10):e109101. doi: 10.1371/journal.pone.0109101. eCollection 2014.

36.

Weak base pairing in both seed and 3' regions reduces RNAi off-targets and enhances si/shRNA designs.

Gu S, Zhang Y, Jin L, Huang Y, Zhang F, Bassik MC, Kampmann M, Kay MA.

Nucleic Acids Res. 2014 Oct 29;42(19):12169-76. doi: 10.1093/nar/gku854. Epub 2014 Sep 30.

37.

Unraveling the mechanism of cell death induced by chemical fibrils.

Julien O, Kampmann M, Bassik MC, Zorn JA, Venditto VJ, Shimbo K, Agard NJ, Shimada K, Rheingold AL, Stockwell BR, Weissman JS, Wells JA.

Nat Chem Biol. 2014 Nov;10(11):969-76. doi: 10.1038/nchembio.1639. Epub 2014 Sep 28.

38.

Functional genomics platform for pooled screening and generation of mammalian genetic interaction maps.

Kampmann M, Bassik MC, Weissman JS.

Nat Protoc. 2014 Aug;9(8):1825-47. doi: 10.1038/nprot.2014.103. Epub 2014 Jul 3. Erratum in: Nat Protoc. 2015 Apr;10(4):643.

39.

Efficient immobilization of mushroom tyrosinase utilizing whole cells from Agaricus bisporus and its application for degradation of bisphenol A.

Kampmann M, Boll S, Kossuch J, Bielecki J, Uhl S, Kleiner B, Wichmann R.

Water Res. 2014 Jun 15;57:295-303. doi: 10.1016/j.watres.2014.03.054. Epub 2014 Mar 28.

PMID:
24727498
40.

Measurement of thrombus resolution using three-dimensional ultrasound assessment of deep vein thrombosis volume.

Zhao L, Prior SJ, Kampmann M, Sorkin JD, Caldwell K, Braganza M, McEvoy S, Lal BK.

J Vasc Surg Venous Lymphat Disord. 2014 Apr;2(2):140-7. doi: 10.1016/j.jvsv.2013.08.009. Epub 2013 Nov 1.

PMID:
26993178
41.

Next-generation NAMPT inhibitors identified by sequential high-throughput phenotypic chemical and functional genomic screens.

Matheny CJ, Wei MC, Bassik MC, Donnelly AJ, Kampmann M, Iwasaki M, Piloto O, Solow-Cordero DE, Bouley DM, Rau R, Brown P, McManus MT, Weissman JS, Cleary ML.

Chem Biol. 2013 Nov 21;20(11):1352-63. doi: 10.1016/j.chembiol.2013.09.014. Epub 2013 Oct 31.

42.

Tracking niche variation over millennial timescales in sympatric killer whale lineages.

Foote AD, Newton J, Ávila-Arcos MC, Kampmann ML, Samaniego JA, Post K, Rosing-Asvid A, Sinding MH, Gilbert MT.

Proc Biol Sci. 2013 Aug 14;280(1768):20131481. doi: 10.1098/rspb.2013.1481. Print 2013 Oct 7.

43.

Integrated platform for genome-wide screening and construction of high-density genetic interaction maps in mammalian cells.

Kampmann M, Bassik MC, Weissman JS.

Proc Natl Acad Sci U S A. 2013 Jun 18;110(25):E2317-26. doi: 10.1073/pnas.1307002110. Epub 2013 Jun 5.

44.

Long-term RNA persistence in postmortem contexts.

Fordyce SL, Kampmann ML, van Doorn NL, Gilbert MT.

Investig Genet. 2013 Apr 23;4(1):7. doi: 10.1186/2041-2223-4-7.

45.

Genetic diversity among pandemic 2009 influenza viruses isolated from a transmission chain.

Fordyce SL, Bragstad K, Pedersen SS, Jensen TG, Gahrn-Hansen B, Daniels R, Hay A, Kampmann ML, Bruhn CA, Moreno-Mayar JV, Ávila-Arcos MC, Gilbert MT, Nielsen LP.

Virol J. 2013 Apr 12;10:116. doi: 10.1186/1743-422X-10-116.

46.

Upper body exercise increases lower extremity venous blood flow in deep venous thrombosis.

Caldwell K, Prior SJ, Kampmann M, Zhao L, McEvoy S, Goldberg AP, Lal BK.

J Vasc Surg Venous Lymphat Disord. 2013 Apr;1(2):126-33. doi: 10.1016/j.jvsv.2012.07.004. Epub 2012 Dec 17.

PMID:
26992332
47.

Mitochondrial genome diversity and population structure of the giant squid Architeuthis: genetics sheds new light on one of the most enigmatic marine species.

Winkelmann I, Campos PF, Strugnell J, Cherel Y, Smith PJ, Kubodera T, Allcock L, Kampmann ML, Schroeder H, Guerra A, Norman M, Finn J, Ingrao D, Clarke M, Gilbert MT.

Proc Biol Sci. 2013 Mar 20;280(1759):20130273. doi: 10.1098/rspb.2013.0273. Print 2013 May 22.

48.

A systematic mammalian genetic interaction map reveals pathways underlying ricin susceptibility.

Bassik MC, Kampmann M, Lebbink RJ, Wang S, Hein MY, Poser I, Weibezahn J, Horlbeck MA, Chen S, Mann M, Hyman AA, Leproust EM, McManus MT, Weissman JS.

Cell. 2013 Feb 14;152(4):909-22. doi: 10.1016/j.cell.2013.01.030. Epub 2013 Feb 8.

49.

Conserved spatial organization of FG domains in the nuclear pore complex.

Atkinson CE, Mattheyses AL, Kampmann M, Simon SM.

Biophys J. 2013 Jan 8;104(1):37-50. doi: 10.1016/j.bpj.2012.11.3823. Epub 2013 Jan 8.

50.

Three-dimensional Ultrasound Assessment of DVT Volume: A Clinical Protocol and Description of the Time-course of Thrombus Resolution.

Zhao L, Prior SJ, Kampmann M, Sorkin JD, Caldwell K, Braganza M, McEvoy S, Goldberg A, Lal BK.

J Vasc Surg Venous Lymphat Disord. 2013 Jan;1(1):113. doi: 10.1016/j.jvsv.2012.10.046. Epub 2012 Dec 8. No abstract available.

PMID:
26993944

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