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Items: 1 to 50 of 288

1.

Cooperative Effects of Vascular Angiogenesis and Lymphangiogenesis.

Osaki T, Serrano JC, Kamm RD.

Regen Eng Transl Med. 2018 Sep;4(3):120-132. doi: 10.1007/s40883-018-0054-2. Epub 2018 Apr 23.

PMID:
30417074
2.

Engineered Models of Metastasis with Application to Study Cancer Biomechanics.

Chen MB, Kamm RD, Moeendarbary E.

Adv Exp Med Biol. 2018;1092:189-207. doi: 10.1007/978-3-319-95294-9_10.

PMID:
30368754
3.

Microphysiological 3D model of amyotrophic lateral sclerosis (ALS) from human iPS-derived muscle cells and optogenetic motor neurons.

Osaki T, Uzel SGM, Kamm RD.

Sci Adv. 2018 Oct 10;4(10):eaat5847. doi: 10.1126/sciadv.aat5847. eCollection 2018 Oct.

4.

Construction of Continuous Capillary Networks Stabilized by Pericyte-like Perivascular Cells.

Yamamoto K, Tanimura K, Watanabe M, Sano H, Uwamori H, Mabuchi Y, Matsuzaki Y, Chung S, Kamm RD, Tanishita K, Sudo R.

Tissue Eng Part A. 2018 Oct 27. doi: 10.1089/ten.TEA.2018.0186. [Epub ahead of print]

PMID:
30234439
5.

3D microfluidic ex vivo culture of organotypic tumor spheroids to model immune checkpoint blockade.

Aref AR, Campisi M, Ivanova E, Portell A, Larios D, Piel BP, Mathur N, Zhou C, Coakley RV, Bartels A, Bowden M, Herbert Z, Hill S, Gilhooley S, Carter J, Cañadas I, Thai TC, Kitajima S, Chiono V, Paweletz CP, Barbie DA, Kamm RD, Jenkins RW.

Lab Chip. 2018 Oct 9;18(20):3129-3143. doi: 10.1039/c8lc00322j.

PMID:
30183789
6.

Complex mechanics of the heterogeneous extracellular matrix in cancer.

Malandrino A, Mak M, Kamm RD, Moeendarbary E.

Extreme Mech Lett. 2018 May;21:25-34. doi: 10.1016/j.eml.2018.02.003. Review.

7.

Corrigendum: Characterizing the Role of Monocytes in T Cell Cancer Immunotherapy Using a 3D Microfluidic Model.

Lee SWL, Adriani G, Ceccarello E, Pavesi A, Tan AT, Bertoletti A, Kamm RD, Wong SC.

Front Immunol. 2018 Jul 24;9:1719. doi: 10.3389/fimmu.2018.01719. eCollection 2018.

8.

Epithelial-Mesenchymal Transition Induces Podocalyxin to Promote Extravasation via Ezrin Signaling.

Fröse J, Chen MB, Hebron KE, Reinhardt F, Hajal C, Zijlstra A, Kamm RD, Weinberg RA.

Cell Rep. 2018 Jul 24;24(4):962-972. doi: 10.1016/j.celrep.2018.06.092.

9.

Hydrogel-incorporating unit in a well: 3D cell culture for high-throughput analysis.

Yu YJ, Kim YH, Na K, Min SY, Hwang OK, Park DK, Kim DY, Choi SH, Kamm RD, Chung S, Kim JA.

Lab Chip. 2018 Aug 21;18(17):2604-2613. doi: 10.1039/c8lc00525g.

PMID:
30043033
10.

Studying TCR T cell anti-tumor activity in a microfluidic intrahepatic tumor model.

Adriani G, Pavesi A, Kamm RD.

Methods Cell Biol. 2018;146:199-214. doi: 10.1016/bs.mcb.2018.05.009. Epub 2018 Jul 12.

PMID:
30037462
11.

3D self-organized microvascular model of the human blood-brain barrier with endothelial cells, pericytes and astrocytes.

Campisi M, Shin Y, Osaki T, Hajal C, Chiono V, Kamm RD.

Biomaterials. 2018 Oct;180:117-129. doi: 10.1016/j.biomaterials.2018.07.014. Epub 2018 Jul 12.

12.

Interstitial flow promotes macrophage polarization toward an M2 phenotype.

Li R, Serrano JC, Xing H, Lee TA, Azizgolshani H, Zaman M, Kamm RD.

Mol Biol Cell. 2018 Aug 8;29(16):1927-1940. doi: 10.1091/mbc.E18-03-0164. Epub 2018 Jul 11.

PMID:
29995595
13.

Influence of protein corona and caveolae-mediated endocytosis on nanoparticle uptake and transcytosis.

Ho YT, Kamm RD, Kah JCY.

Nanoscale. 2018 Jul 9;10(26):12386-12397. doi: 10.1039/c8nr02393j.

PMID:
29926047
14.

Inflamed neutrophils sequestered at entrapped tumor cells via chemotactic confinement promote tumor cell extravasation.

Chen MB, Hajal C, Benjamin DC, Yu C, Azizgolshani H, Hynes RO, Kamm RD.

Proc Natl Acad Sci U S A. 2018 Jul 3;115(27):7022-7027. doi: 10.1073/pnas.1715932115. Epub 2018 Jun 18.

PMID:
29915060
15.

In vitro models of molecular and nano-particle transport across the blood-brain barrier.

Hajal C, Campisi M, Mattu C, Chiono V, Kamm RD.

Biomicrofluidics. 2018 May 31;12(4):042213. doi: 10.1063/1.5027118. eCollection 2018 Jul.

PMID:
29887937
16.

Evidence from ITIR-FCS Diffusion Studies that the Amyloid-Beta (Aβ) Peptide Does Not Perturb Plasma Membrane Fluidity in Neuronal Cells.

Ng J, Kamm RD, Wohland T, Kraut RS.

J Mol Biol. 2018 Sep 14;430(18 Pt B):3439-3453. doi: 10.1016/j.jmb.2018.04.030. Epub 2018 May 7.

PMID:
29746852
17.

Vascularized microfluidic organ-chips for drug screening, disease models and tissue engineering.

Osaki T, Sivathanu V, Kamm RD.

Curr Opin Biotechnol. 2018 Aug;52:116-123. doi: 10.1016/j.copbio.2018.03.011. Epub 2018 Apr 12. Review.

PMID:
29656237
18.

Cell contraction induces long-ranged stress stiffening in the extracellular matrix.

Han YL, Ronceray P, Xu G, Malandrino A, Kamm RD, Lenz M, Broedersz CP, Guo M.

Proc Natl Acad Sci U S A. 2018 Apr 17;115(16):4075-4080. doi: 10.1073/pnas.1722619115. Epub 2018 Apr 4.

19.

Engineered 3D vascular and neuronal networks in a microfluidic platform.

Osaki T, Sivathanu V, Kamm RD.

Sci Rep. 2018 Mar 26;8(1):5168. doi: 10.1038/s41598-018-23512-1.

20.

Characterizing the Role of Monocytes in T Cell Cancer Immunotherapy Using a 3D Microfluidic Model.

Lee SWL, Adriani G, Ceccarello E, Pavesi A, Tan AT, Bertoletti A, Kamm RD, Wong SC.

Front Immunol. 2018 Mar 6;9:416. doi: 10.3389/fimmu.2018.00416. eCollection 2018. Erratum in: Front Immunol. 2018 Jul 24;9:1719.

21.

The effects of monocytes on tumor cell extravasation in a 3D vascularized microfluidic model.

Boussommier-Calleja A, Atiyas Y, Haase K, Headley M, Lewis C, Kamm RD.

Biomaterials. 2018 Mar 5. pii: S0142-9612(18)30164-9. doi: 10.1016/j.biomaterials.2018.03.005. [Epub ahead of print]

PMID:
29548546
22.

In Vitro Modeling of Mechanics in Cancer Metastasis.

Malandrino A, Kamm RD, Moeendarbary E.

ACS Biomater Sci Eng. 2018 Feb 12;4(2):294-301. doi: 10.1021/acsbiomaterials.7b00041. Epub 2017 May 16. Review.

23.

Computational modeling of three-dimensional ECM-rigidity sensing to guide directed cell migration.

Kim MC, Silberberg YR, Abeyaratne R, Kamm RD, Asada HH.

Proc Natl Acad Sci U S A. 2018 Jan 16;115(3):E390-E399. doi: 10.1073/pnas.1717230115. Epub 2018 Jan 2.

24.

Crosstalk between developing vasculature and optogenetically engineered skeletal muscle improves muscle contraction and angiogenesis.

Osaki T, Sivathanu V, Kamm RD.

Biomaterials. 2018 Feb;156:65-76. doi: 10.1016/j.biomaterials.2017.11.041. Epub 2017 Nov 25.

PMID:
29190499
25.

Cell-Extracellular Matrix Mechanobiology: Forceful Tools and Emerging Needs for Basic and Translational Research.

Holle AW, Young JL, Van Vliet KJ, Kamm RD, Discher D, Janmey P, Spatz JP, Saif T.

Nano Lett. 2018 Jan 10;18(1):1-8. doi: 10.1021/acs.nanolett.7b04982. Epub 2017 Dec 6.

26.

Ex Vivo Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids.

Jenkins RW, Aref AR, Lizotte PH, Ivanova E, Stinson S, Zhou CW, Bowden M, Deng J, Liu H, Miao D, He MX, Walker W, Zhang G, Tian T, Cheng C, Wei Z, Palakurthi S, Bittinger M, Vitzthum H, Kim JW, Merlino A, Quinn M, Venkataramani C, Kaplan JA, Portell A, Gokhale PC, Phillips B, Smart A, Rotem A, Jones RE, Keogh L, Anguiano M, Stapleton L, Jia Z, Barzily-Rokni M, Cañadas I, Thai TC, Hammond MR, Vlahos R, Wang ES, Zhang H, Li S, Hanna GJ, Huang W, Hoang MP, Piris A, Eliane JP, Stemmer-Rachamimov AO, Cameron L, Su MJ, Shah P, Izar B, Thakuria M, LeBoeuf NR, Rabinowits G, Gunda V, Parangi S, Cleary JM, Miller BC, Kitajima S, Thummalapalli R, Miao B, Barbie TU, Sivathanu V, Wong J, Richards WG, Bueno R, Yoon CH, Miret J, Herlyn M, Garraway LA, Van Allen EM, Freeman GJ, Kirschmeier PT, Lorch JH, Ott PA, Hodi FS, Flaherty KT, Kamm RD, Boland GM, Wong KK, Dornan D, Paweletz CP, Barbie DA.

Cancer Discov. 2018 Feb;8(2):196-215. doi: 10.1158/2159-8290.CD-17-0833. Epub 2017 Nov 3.

PMID:
29101162
27.

ADAM8 expression in breast cancer derived brain metastases: Functional implications on MMP-9 expression and transendothelial migration in breast cancer cells.

Conrad C, Götte M, Schlomann U, Roessler M, Pagenstecher A, Anderson P, Preston J, Pruessmeyer J, Ludwig A, Li R, Kamm RD, Ritz R, Carl B, Nimsky C, Bartsch JW.

Int J Cancer. 2018 Feb 15;142(4):779-791. doi: 10.1002/ijc.31090. Epub 2017 Oct 31.

PMID:
28986926
28.

In Vitro Microfluidic Models for Neurodegenerative Disorders.

Osaki T, Shin Y, Sivathanu V, Campisi M, Kamm RD.

Adv Healthc Mater. 2018 Jan;7(2). doi: 10.1002/adhm.201700489. Epub 2017 Sep 7. Review.

PMID:
28881425
29.

A 3D microfluidic model for preclinical evaluation of TCR-engineered T cells against solid tumors.

Pavesi A, Tan AT, Koh S, Chia A, Colombo M, Antonecchia E, Miccolis C, Ceccarello E, Adriani G, Raimondi MT, Kamm RD, Bertoletti A.

JCI Insight. 2017 Jun 15;2(12). pii: 89762. doi: 10.1172/jci.insight.89762. [Epub ahead of print]

30.

Emerging Trends in Micro- and Nanoscale Technologies in Medicine: From Basic Discoveries to Translation.

Alvarez MM, Aizenberg J, Analoui M, Andrews AM, Bisker G, Boyden ES, Kamm RD, Karp JM, Mooney DJ, Oklu R, Peer D, Stolzoff M, Strano MS, Trujillo-de Santiago G, Webster TJ, Weiss PS, Khademhosseini A.

ACS Nano. 2017 Jun 27;11(6):5195-5214. doi: 10.1021/acsnano.7b01493. Epub 2017 May 19.

PMID:
28524668
31.

Integrated Analysis of Intracellular Dynamics of MenaINV Cancer Cells in a 3D Matrix.

Mak M, Anderson S, McDonough MC, Spill F, Kim JE, Boussommier-Calleja A, Zaman MH, Kamm RD.

Biophys J. 2017 May 9;112(9):1874-1884. doi: 10.1016/j.bpj.2017.03.030.

32.

A versatile microfluidic device for high throughput production of microparticles and cell microencapsulation.

Akbari S, Pirbodaghi T, Kamm RD, Hammond PT.

Lab Chip. 2017 Jun 13;17(12):2067-2075. doi: 10.1039/c6lc01568a.

PMID:
28492663
33.

Endothelial monolayer permeability under controlled oxygen tension.

Funamoto K, Yoshino D, Matsubara K, Zervantonakis IK, Funamoto K, Nakayama M, Masamune J, Kimura Y, Kamm RD.

Integr Biol (Camb). 2017 Jun 19;9(6):529-538. doi: 10.1039/c7ib00068e.

PMID:
28488717
34.

A Facile Method to Probe the Vascular Permeability of Nanoparticles in Nanomedicine Applications.

Ho YT, Adriani G, Beyer S, Nhan PT, Kamm RD, Kah JCY.

Sci Rep. 2017 Mar 31;7(1):707. doi: 10.1038/s41598-017-00750-3.

35.

On-chip human microvasculature assay for visualization and quantification of tumor cell extravasation dynamics.

Chen MB, Whisler JA, Fröse J, Yu C, Shin Y, Kamm RD.

Nat Protoc. 2017 May;12(5):865-880. doi: 10.1038/nprot.2017.018. Epub 2017 Mar 30.

36.

Advances in on-chip vascularization.

Haase K, Kamm RD.

Regen Med. 2017 Apr;12(3):285-302. doi: 10.2217/rme-2016-0152. Epub 2017 Mar 20. Review.

37.

A process engineering approach to increase organoid yield.

Arora N, Imran Alsous J, Guggenheim JW, Mak M, Munera J, Wells JM, Kamm RD, Asada HH, Shvartsman SY, Griffith LG.

Development. 2017 Mar 15;144(6):1128-1136. doi: 10.1242/dev.142919. Epub 2017 Feb 7.

38.

Morphological Transformation and Force Generation of Active Cytoskeletal Networks.

Bidone TC, Jung W, Maruri D, Borau C, Kamm RD, Kim T.

PLoS Comput Biol. 2017 Jan 23;13(1):e1005277. doi: 10.1371/journal.pcbi.1005277. eCollection 2017 Jan.

39.

Dynamic interplay between tumour, stroma and immune system can drive or prevent tumour progression.

Seager RJ, Hajal C, Spill F, Kamm RD, Zaman MH.

Converg Sci Phys Oncol. 2017;3. pii: 034002. doi: 10.1088/2057-1739/aa7e86. Epub 2017 Jul 28.

40.

A 3D neurovascular microfluidic model consisting of neurons, astrocytes and cerebral endothelial cells as a blood-brain barrier.

Adriani G, Ma D, Pavesi A, Kamm RD, Goh EL.

Lab Chip. 2017 Jan 31;17(3):448-459. doi: 10.1039/c6lc00638h.

PMID:
28001148
41.

Macrophage-Secreted TNFα and TGFβ1 Influence Migration Speed and Persistence of Cancer Cells in 3D Tissue Culture via Independent Pathways.

Li R, Hebert JD, Lee TA, Xing H, Boussommier-Calleja A, Hynes RO, Lauffenburger DA, Kamm RD.

Cancer Res. 2017 Jan 15;77(2):279-290. doi: 10.1158/0008-5472.CAN-16-0442. Epub 2016 Nov 21.

42.

A Chemomechanical Model for Nuclear Morphology and Stresses during Cell Transendothelial Migration.

Cao X, Moeendarbary E, Isermann P, Davidson PM, Wang X, Chen MB, Burkart AK, Lammerding J, Kamm RD, Shenoy VB.

Biophys J. 2016 Oct 4;111(7):1541-1552. doi: 10.1016/j.bpj.2016.08.011.

43.

Breast Cancer Cell Invasion into a Three Dimensional Tumor-Stroma Microenvironment.

Truong D, Puleo J, Llave A, Mouneimne G, Kamm RD, Nikkhah M.

Sci Rep. 2016 Sep 28;6:34094. doi: 10.1038/srep34094.

44.

Warburg metabolism in tumor-conditioned macrophages promotes metastasis in human pancreatic ductal adenocarcinoma.

Penny HL, Sieow JL, Adriani G, Yeap WH, See Chi Ee P, San Luis B, Lee B, Lee T, Mak SY, Ho YS, Lam KP, Ong CK, Huang RY, Ginhoux F, Rotzschke O, Kamm RD, Wong SC.

Oncoimmunology. 2016 Jun 21;5(8):e1191731. doi: 10.1080/2162402X.2016.1191731. eCollection 2016 Aug.

45.

Microfluidic device for the formation of optically excitable, three-dimensional, compartmentalized motor units.

Uzel SG, Platt RJ, Subramanian V, Pearl TM, Rowlands CJ, Chan V, Boyer LA, So PT, Kamm RD.

Sci Adv. 2016 Aug 3;2(8):e1501429. doi: 10.1126/sciadv.1501429. eCollection 2016 Aug.

46.

Effects of 3D geometries on cellular gradient sensing and polarization.

Spill F, Andasari V, Mak M, Kamm RD, Zaman MH.

Phys Biol. 2016 Jun 25;13(3):036008. doi: 10.1088/1478-3975/13/3/036008.

47.

Cell adhesion during bullet motion in capillaries.

Takeishi N, Imai Y, Ishida S, Omori T, Kamm RD, Ishikawa T.

Am J Physiol Heart Circ Physiol. 2016 Aug 1;311(2):H395-403. doi: 10.1152/ajpheart.00241.2016. Epub 2016 Jun 3.

48.

Engineering a 3D microfluidic culture platform for tumor-treating field application.

Pavesi A, Adriani G, Tay A, Warkiani ME, Yeap WH, Wong SC, Kamm RD.

Sci Rep. 2016 May 24;6:26584. doi: 10.1038/srep26584.

49.

Microfluidic models for adoptive cell-mediated cancer immunotherapies.

Adriani G, Pavesi A, Tan AT, Bertoletti A, Thiery JP, Kamm RD.

Drug Discov Today. 2016 Sep;21(9):1472-1478. doi: 10.1016/j.drudis.2016.05.006. Epub 2016 May 13. Review.

50.

PO-12 - The key role of talin-1 in cancer cell extravasation dissected through human vascularized 3D microfluidic model.

Gilardi M, Bersini S, Calleja AB, Kamm RD, Vanoni M, Moretti M.

Thromb Res. 2016 Apr;140 Suppl 1:S180-1. doi: 10.1016/S0049-3848(16)30145-1. Epub 2016 Apr 8.

PMID:
27161700

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