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Items: 35

1.

Development of a Novel Model of Central Retinal Vascular Occlusion and the Therapeutic Potential of the Adrenomedullin-Receptor Activity-Modifying Protein 2 System.

Hirabayashi K, Tanaka M, Imai A, Toriyama Y, Iesato Y, Sakurai T, Kamiyoshi A, Ichikawa-Shindo Y, Kawate H, Tanaka M, Dai K, Cui N, Wei Y, Nakamura K, Iida S, Matsui S, Yamauchi A, Murata T, Shindo T.

Am J Pathol. 2019 Feb;189(2):449-466. doi: 10.1016/j.ajpath.2018.10.021. Epub 2019 Jan 15.

PMID:
30658846
2.

RAMP3 deficiency enhances postmenopausal obesity and metabolic disorders.

Liu T, Kamiyoshi A, Tanaka M, Iida S, Sakurai T, Ichikawa-Shindo Y, Kawate H, Hirabayashi K, Dai K, Cui N, Tanaka M, Wei Y, Nakamura K, Matsui S, Yamauchi A, Shindo T.

Peptides. 2018 Dec;110:10-18. doi: 10.1016/j.peptides.2018.10.006. Epub 2018 Oct 29.

PMID:
30385288
3.

Isolation and Analysis of a Genome-Edited Single-Hepatocyte from a Cas9 Transgenic Mouse Line.

Sakurai T, Kamiyoshi A, Ohtsuka M, Gurumurthy CB, Sato M, Shindo T.

Methods Mol Biol. 2019;1874:257-271. doi: 10.1007/978-1-4939-8831-0_15.

PMID:
30353519
4.

Regulation of cardiovascular development and homeostasis by the adrenomedullin-RAMP system.

Shindo T, Tanaka M, Kamiyoshi A, Ichikawa-Shindo Y, Kawate H, Yamauchi A, Sakurai T.

Peptides. 2019 Jan;111:55-61. doi: 10.1016/j.peptides.2018.04.004. Epub 2018 Apr 22. Review.

PMID:
29689347
5.

Endogenous calcitonin gene-related peptide suppresses ischemic brain injuries and progression of cognitive decline.

Zhai L, Sakurai T, Kamiyoshi A, Ichikawa-Shindo Y, Kawate H, Tanaka M, Xian X, Hirabayashi K, Dai K, Cui N, Tanimura K, Liu T, Wei Y, Tanaka M, Tomiyama H, Yamauchi A, Igarashi K, Shindo T.

J Hypertens. 2018 Apr;36(4):876-891. doi: 10.1097/HJH.0000000000001649.

PMID:
29266061
6.

Placental extract ameliorates non-alcoholic steatohepatitis (NASH) by exerting protective effects on endothelial cells.

Yamauchi A, Kamiyoshi A, Koyama T, Iinuma N, Yamaguchi S, Miyazaki H, Hirano E, Kaku T, Shindo T.

Heliyon. 2017 Sep 27;3(9):e00416. doi: 10.1016/j.heliyon.2017.e00416. eCollection 2017 Sep.

7.

Vasoprotective Activities of the Adrenomedullin-RAMP2 System in Endothelial Cells.

Xian X, Sakurai T, Kamiyoshi A, Ichikawa-Shindo Y, Tanaka M, Koyama T, Kawate H, Yang L, Liu T, Imai A, Zhai L, Hirabayashi K, Dai K, Tanimura K, Liu T, Cui N, Igarashi K, Yamauchi A, Shindo T.

Endocrinology. 2017 May 1;158(5):1359-1372. doi: 10.1210/en.2016-1531.

PMID:
28324104
8.

Endogenous Calcitonin Gene-Related Peptide Regulates Lipid Metabolism and Energy Homeostasis in Male Mice.

Liu T, Kamiyoshi A, Sakurai T, Ichikawa-Shindo Y, Kawate H, Yang L, Tanaka M, Xian X, Imai A, Zhai L, Hirabayashi K, Dai K, Tanimura K, Liu T, Cui N, Igarashi K, Yamauchi A, Shindo T.

Endocrinology. 2017 May 1;158(5):1194-1206. doi: 10.1210/en.2016-1510.

PMID:
28324021
9.

Adrenomedullin Suppresses Vascular Endothelial Growth Factor-Induced Vascular Hyperpermeability and Inflammation in Retinopathy.

Imai A, Toriyama Y, Iesato Y, Hirabayashi K, Sakurai T, Kamiyoshi A, Ichikawa-Shindo Y, Kawate H, Tanaka M, Liu T, Xian X, Zhai L, Dai K, Tanimura K, Liu T, Cui N, Yamauchi A, Murata T, Shindo T.

Am J Pathol. 2017 May;187(5):999-1015. doi: 10.1016/j.ajpath.2017.01.014. Epub 2017 Mar 17.

PMID:
28322199
10.

The endothelial adrenomedullin-RAMP2 system regulates vascular integrity and suppresses tumour metastasis.

Tanaka M, Koyama T, Sakurai T, Kamiyoshi A, Ichikawa-Shindo Y, Kawate H, Liu T, Xian X, Imai A, Zhai L, Hirabayashi K, Owa S, Yamauchi A, Igarashi K, Taniguchi S, Shindo T.

Cardiovasc Res. 2016 Sep;111(4):398-409. doi: 10.1093/cvr/cvw166. Epub 2016 Jun 15.

PMID:
27307317
11.

A non-inheritable maternal Cas9-based multiple-gene editing system in mice.

Sakurai T, Kamiyoshi A, Kawate H, Mori C, Watanabe S, Tanaka M, Uetake R, Sato M, Shindo T.

Sci Rep. 2016 Jan 28;6:20011. doi: 10.1038/srep20011.

12.

Adrenomedullin-RAMP2 System in Vascular Endothelial Cells.

Koyama T, Sakurai T, Kamiyoshi A, Ichikawa-Shindo Y, Kawate H, Shindo T.

J Atheroscler Thromb. 2015 Jul 23;22(7):647-53. doi: 10.5551/jat.29967. Epub 2015 Jun 4. Review.

13.

Pathophysiological function of endogenous calcitonin gene-related peptide in ocular vascular diseases.

Toriyama Y, Iesato Y, Imai A, Sakurai T, Kamiyoshi A, Ichikawa-Shindo Y, Kawate H, Yamauchi A, Igarashi K, Tanaka M, Liu T, Xian X, Zhai L, Owa S, Murata T, Shindo T.

Am J Pathol. 2015 Jun;185(6):1783-94. doi: 10.1016/j.ajpath.2015.02.017. Epub 2015 Apr 7.

PMID:
25857228
14.

Functional differentiation of RAMP2 and RAMP3 in their regulation of the vascular system.

Yamauchi A, Sakurai T, Kamiyoshi A, Ichikawa-Shindo Y, Kawate H, Igarashi K, Toriyama Y, Tanaka M, Liu T, Xian X, Imai A, Zhai L, Owa S, Arai T, Shindo T.

J Mol Cell Cardiol. 2014 Dec;77:73-85. doi: 10.1016/j.yjmcc.2014.09.017. Epub 2014 Sep 28.

PMID:
25264174
15.

Pathophysiological roles of adrenomedullin-RAMP2 system in acute and chronic cerebral ischemia.

Igarashi K, Sakurai T, Kamiyoshi A, Ichikawa-Shindo Y, Kawate H, Yamauchi A, Toriyama Y, Tanaka M, Liu T, Xian X, Imai A, Zhai L, Owa S, Koyama T, Uetake R, Ihara M, Shindo T.

Peptides. 2014 Dec;62:21-31. doi: 10.1016/j.peptides.2014.08.013. Epub 2014 Sep 22.

PMID:
25252154
16.

A single blastocyst assay optimized for detecting CRISPR/Cas9 system-induced indel mutations in mice.

Sakurai T, Watanabe S, Kamiyoshi A, Sato M, Shindo T.

BMC Biotechnol. 2014 Jul 21;14:69. doi: 10.1186/1472-6750-14-69.

17.

[Pathophysiological roles of adrenomedullin and its receptor activity modifying system].

Shindo T, Sakurai T, Kamiyoshi A, Ichikawa-Shindo Y, Kawate H, Koyama T.

Nihon Yakurigaku Zasshi. 2014 May;143(5):232-5. Review. Japanese. No abstract available.

PMID:
24813793
18.

Adrenomedullin-RAMP2 system suppresses ER stress-induced tubule cell death and is involved in kidney protection.

Uetake R, Sakurai T, Kamiyoshi A, Ichikawa-Shindo Y, Kawate H, Iesato Y, Yoshizawa T, Koyama T, Yang L, Toriyama Y, Yamauchi A, Igarashi K, Tanaka M, Kuwabara T, Mori K, Yanagita M, Mukoyama M, Shindo T.

PLoS One. 2014 Feb 5;9(2):e87667. doi: 10.1371/journal.pone.0087667. eCollection 2014.

19.

Regulation of adrenomedullin and its family peptide by RAMP system--lessons from genetically engineered mice.

Shindo T, Sakurai T, Kamiyoshi A, Ichikawa-Shindo Y, Shimoyama N, Iinuma N, Arai T, Miyagawa S.

Curr Protein Pept Sci. 2013 Aug;14(5):347-57. Review.

PMID:
23745699
20.

Adrenomedullin-RAMP2 system is crucially involved in retinal angiogenesis.

Iesato Y, Toriyama Y, Sakurai T, Kamiyoshi A, Ichikawa-Shindo Y, Kawate H, Yoshizawa T, Koyama T, Uetake R, Yang L, Yamauchi A, Tanaka M, Igarashi K, Murata T, Shindo T.

Am J Pathol. 2013 Jun;182(6):2380-90. doi: 10.1016/j.ajpath.2013.02.015. Epub 2013 Apr 4.

PMID:
23562442
21.

Endogenous CGRP protects against neointimal hyperplasia following wire-induced vascular injury.

Yang L, Sakurai T, Kamiyoshi A, Ichikawa-Shindo Y, Kawate H, Yoshizawa T, Koyama T, Iesato Y, Uetake R, Yamauchi A, Tanaka M, Toriyama Y, Igarashi K, Shindo T.

J Mol Cell Cardiol. 2013 Jun;59:55-66. doi: 10.1016/j.yjmcc.2013.02.002. Epub 2013 Feb 15.

PMID:
23416515
22.

Vascular endothelial adrenomedullin-RAMP2 system is essential for vascular integrity and organ homeostasis.

Koyama T, Ochoa-Callejero L, Sakurai T, Kamiyoshi A, Ichikawa-Shindo Y, Iinuma N, Arai T, Yoshizawa T, Iesato Y, Lei Y, Uetake R, Okimura A, Yamauchi A, Tanaka M, Igarashi K, Toriyama Y, Kawate H, Adams RH, Kawakami H, Mochizuki N, Martínez A, Shindo T.

Circulation. 2013 Feb 19;127(7):842-53. doi: 10.1161/CIRCULATIONAHA.112.000756. Epub 2013 Jan 25.

PMID:
23355623
23.

Novel regulation of cardiac metabolism and homeostasis by the adrenomedullin-receptor activity-modifying protein 2 system.

Yoshizawa T, Sakurai T, Kamiyoshi A, Ichikawa-Shindo Y, Kawate H, Iesato Y, Koyama T, Uetake R, Yang L, Yamauchi A, Tanaka M, Toriyama Y, Igarashi K, Nakada T, Kashihara T, Yamada M, Kawakami H, Nakanishi H, Taguchi R, Nakanishi T, Akazawa H, Shindo T.

Hypertension. 2013 Feb;61(2):341-51. doi: 10.1161/HYPERTENSIONAHA.111.00647. Epub 2013 Jan 7.

PMID:
23297372
24.

Induction of LYVE-1/stabilin-2-positive liver sinusoidal endothelial-like cells from embryoid bodies by modulation of adrenomedullin-RAMP2 signaling.

Arai T, Sakurai T, Kamiyoshi A, Ichikawa-Shindo Y, Iinuma N, Iesato Y, Koyama T, Yoshizawa T, Uetake R, Yamauchi A, Yang L, Kawate H, Ogawa S, Kobayashi A, Miyagawa S, Shindo T.

Peptides. 2011 Sep;32(9):1855-65. doi: 10.1016/j.peptides.2011.07.005. Epub 2011 Jul 14.

PMID:
21782867
25.

Adrenomedullin in sinusoidal endothelial cells play protective roles against cold injury of liver.

Iinuma N, Sakurai T, Kamiyoshi A, Ichikawa-Shindo Y, Arai T, Yoshizawa T, Koyama T, Uetake R, Kawate H, Muto S, Tagawa Y, Miyagawa S, Shindo T.

Peptides. 2010 May;31(5):865-71. doi: 10.1016/j.peptides.2010.01.011. Epub 2010 Feb 2.

PMID:
20132855
26.

Endogenous alpha-calcitonin gene-related peptide mitigates liver fibrosis in chronic hepatitis induced by repeated administration of concanavalin A.

Kamiyoshi A, Sakurai T, Ichikawa-Shindo Y, Iinuma N, Kawate H, Yoshizawa T, Koyama T, Muto S, Shindo T.

Liver Int. 2009 May;29(5):642-9. doi: 10.1111/j.1478-3231.2008.01841.x. Epub 2008 Jul 30.

PMID:
18673438
27.

The GPCR modulator protein RAMP2 is essential for angiogenesis and vascular integrity.

Ichikawa-Shindo Y, Sakurai T, Kamiyoshi A, Kawate H, Iinuma N, Yoshizawa T, Koyama T, Fukuchi J, Iimuro S, Moriyama N, Kawakami H, Murata T, Kangawa K, Nagai R, Shindo T.

J Clin Invest. 2008 Jan;118(1):29-39.

28.

Rapid zygosity determination in mice by SYBR Green real-time genomic PCR of a crude DNA solution.

Sakurai T, Kamiyoshi A, Watanabe S, Sato M, Shindo T.

Transgenic Res. 2008 Feb;17(1):149-55. Epub 2007 Sep 13.

PMID:
17851772
29.

Endogenous alphaCGRP protects against concanavalin A-induced hepatitis in mice.

Kamiyoshi A, Sakurai T, Ichikawa-Shindo Y, Fukuchi J, Kawate H, Muto S, Tagawa Y, Shindo T.

Biochem Biophys Res Commun. 2006 Apr 28;343(1):152-8. Epub 2006 Mar 3.

PMID:
16530166
30.

Characterization of cytochrome P450 expression in murine embryonic stem cell-derived hepatic tissue system.

Tsutsui M, Ogawa S, Inada Y, Tomioka E, Kamiyoshi A, Tanaka S, Kishida T, Nishiyama M, Murakami M, Kuroda J, Hashikura Y, Miyagawa S, Satoh F, Shibata N, Tagawa Y.

Drug Metab Dispos. 2006 Apr;34(4):696-701. Epub 2006 Jan 13.

PMID:
16415121
31.

Suppression of cell death in primary rat hepatocytes by alpha1-acid glycoprotein.

Kagaya N, Kamiyoshi A, Tagawa Y, Akamatsu S, Isoda K, Kawase M, Yagi K.

J Biosci Bioeng. 2005 Jan;99(1):81-3.

PMID:
16233760
32.

Novel function of rare catechin, epigallocatechin-3-(3''-O-methyl)gallate, against cold injury in primary rat hepatocytes.

Kagaya N, Hara Y, Saijo R, Kamiyoshi A, Tagawa Y, Kawase M, Yagi K.

J Biosci Bioeng. 2003;96(6):559-63.

PMID:
16233573
33.

Crucial roles of mesodermal cell lineages in a murine embryonic stem cell-derived in vitro liver organogenesis system.

Ogawa S, Tagawa Y, Kamiyoshi A, Suzuki A, Nakayama J, Hashikura Y, Miyagawa S.

Stem Cells. 2005 Aug;23(7):903-13.

34.

Liver protection by bis(maltolato)zinc(II) complex.

Kawase M, Kagaya N, Akamatsu S, Kamiyoshi A, Muto S, Tagawa Y, Yagi K.

Exp Anim. 2004 Jan;53(1):1-9.

35.

Survival and function of mouse embryonic stem cell-derived cardiomyocytes in ectopic transplants.

Johkura K, Cui L, Suzuki A, Teng R, Kamiyoshi A, Okamura S, Kubota S, Zhao X, Asanuma K, Okouchi Y, Ogiwara N, Tagawa Yi, Sasaki K.

Cardiovasc Res. 2003 May 1;58(2):435-43.

PMID:
12757877

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