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Items: 1 to 50 of 145

1.

Identification of cytochrome P450 oxidoreductase gene variants that are significantly associated with the interindividual variations in warfarin maintenance dose.

Zhang X, Li L, Ding X, Kaminsky LS.

Drug Metab Dispos. 2011 Aug;39(8):1433-9. doi: 10.1124/dmd.111.038836. Epub 2011 May 11.

2.

Investigations of the posttranslational mechanism of arsenite-mediated downregulation of human cytochrome P4501A1 levels: the role of heme oxygenase-1.

Bessette EE, Fasco MJ, Pentecost BT, Reilly A, Kaminsky LS.

J Biochem Mol Toxicol. 2009 May-Jun;23(3):222-32. doi: 10.1002/jbt.20283.

PMID:
19526463
3.

Induction of CYP1A1 and CYP1B1 by benzo(k)fluoranthene and benzo(a)pyrene in T-47D human breast cancer cells: roles of PAH interactions and PAH metabolites.

Spink DC, Wu SJ, Spink BC, Hussain MM, Vakharia DD, Pentecost BT, Kaminsky LS.

Toxicol Appl Pharmacol. 2008 Feb 1;226(3):213-24. Epub 2007 Sep 5.

4.

Determination of the role of target tissue metabolism in lung carcinogenesis using conditional cytochrome P450 reductase-null mice.

Weng Y, Fang C, Turesky RJ, Behr M, Kaminsky LS, Ding X.

Cancer Res. 2007 Aug 15;67(16):7825-32.

5.

Role of small intestinal cytochromes p450 in the bioavailability of oral nifedipine.

Zhang QY, Kaminsky LS, Dunbar D, Zhang J, Ding X.

Drug Metab Dispos. 2007 Sep;35(9):1617-23. Epub 2007 Jun 13.

PMID:
17567730
6.

Mechanisms of arsenite-mediated decreases in benzo[k]fluoranthene-induced human cytochrome P4501A1 levels in HepG2 cells.

Bessette EE, Fasco MJ, Pentecost BT, Kaminsky LS.

Drug Metab Dispos. 2005 Mar;33(3):312-20. Epub 2004 Dec 2.

PMID:
15576448
7.

Gene-environment interaction signatures by quantitative mRNA profiling in exfoliated buccal mucosal cells.

Spivack SD, Hurteau GJ, Jain R, Kumar SV, Aldous KM, Gierthy JF, Kaminsky LS.

Cancer Res. 2004 Sep 15;64(18):6805-13.

8.

Phase I and II carcinogen metabolism gene expression in human lung tissue and tumors.

Spivack SD, Hurteau GJ, Fasco MJ, Kaminsky LS.

Clin Cancer Res. 2003 Dec 1;9(16 Pt 1):6002-11.

9.

The small intestine as a xenobiotic-metabolizing organ.

Kaminsky LS, Zhang QY.

Drug Metab Dispos. 2003 Dec;31(12):1520-5. Review. No abstract available.

PMID:
14625348
10.

Characterization of mouse small intestinal cytochrome P450 expression.

Zhang QY, Dunbar D, Kaminsky LS.

Drug Metab Dispos. 2003 Nov;31(11):1346-51.

PMID:
14570766
12.
13.

Induction of CYP1A1 and CYP1B1 in T-47D human breast cancer cells by benzo[a]pyrene is diminished by arsenite.

Spink DC, Katz BH, Hussain MM, Spink BC, Wu SJ, Liu N, Pause R, Kaminsky LS.

Drug Metab Dispos. 2002 Mar;30(3):262-9.

PMID:
11854143
14.

Polycyclic aromatic hydrocarbon/metal mixtures: effect on PAH induction of CYP1A1 in human HEPG2 cells.

Vakharia DD, Liu N, Pause R, Fasco M, Bessette E, Zhang QY, Kaminsky LS.

Drug Metab Dispos. 2001 Jul;29(7):999-1006.

PMID:
11408366
15.

Induction of CYP1A by benzo[k]fluoranthene in human hepatocytes: CYP1A1 or CYP1A2?

Liu N, Zhang QY, Vakharia D, Dunbar D, Kaminsky LS.

Arch Biochem Biophys. 2001 May 1;389(1):130-4.

PMID:
11370663
16.

CYP1B1 expression in human lung.

Spivack SD, Hurteau GJ, Reilly AA, Aldous KM, Ding X, Kaminsky LS.

Drug Metab Dispos. 2001 Jun;29(6):916-22.

PMID:
11353763
17.

Metabolic characterization of the major human small intestinal cytochrome p450s.

Obach RS, Zhang QY, Dunbar D, Kaminsky LS.

Drug Metab Dispos. 2001 Mar;29(3):347-52.

PMID:
11181505
18.

Effect of metals on polycyclic aromatic hydrocarbon induction of CYP1A1 and CYP1A2 in human hepatocyte cultures.

Vakharia DD, Liu N, Pause R, Fasco M, Bessette E, Zhang QY, Kaminsky LS.

Toxicol Appl Pharmacol. 2001 Jan 15;170(2):93-103.

PMID:
11162773
19.

Induction of mouse CYP2J by pyrazole in the eye, kidney, liver, lung, olfactory mucosa, and small intestine, but not in the heart.

Xie Q, Zhang QY, Zhang Y, Su T, Gu J, Kaminsky LS, Ding X.

Drug Metab Dispos. 2000 Nov;28(11):1311-6.

PMID:
11038158
20.

Cytochromes P450 and cancer.

Kaminsky LS, Spivack SD.

Mol Aspects Med. 1999 Feb-Apr;20(1-2):70-84, 137. Review. No abstract available.

PMID:
10575653
21.

Induction of rat small intestinal cytochrome P-450 2J4.

Zhang QY, Ding X, Dunbar D, Cao L, Kaminsky LS.

Drug Metab Dispos. 1999 Oct;27(10):1123-7.

PMID:
10497137
22.

Characterization of human small intestinal cytochromes P-450.

Zhang QY, Dunbar D, Ostrowska A, Zeisloft S, Yang J, Kaminsky LS.

Drug Metab Dispos. 1999 Jul;27(7):804-9.

PMID:
10383924
23.

Biotransformation of coumarin by rodent and human cytochromes P-450: metabolic basis of tissue-selective toxicity in olfactory mucosa of rats and mice.

Zhuo X, Gu J, Zhang QY, Spink DC, Kaminsky LS, Ding X.

J Pharmacol Exp Ther. 1999 Feb;288(2):463-71.

PMID:
9918546
24.

Caffeine based measures of CYP1A2 activity correlate with oral clearance of tacrine in patients with Alzheimer's disease.

Fontana RJ, deVries TM, Woolf TF, Knapp MJ, Brown AS, Kaminsky LS, Tang BK, Foster NL, Brown RR, Watkins PB.

Br J Clin Pharmacol. 1998 Sep;46(3):221-8.

25.

16Alpha-hydroxylation of estrone by human cytochrome P4503A4/5.

Huang Z, Guengerich FP, Kaminsky LS.

Carcinogenesis. 1998 May;19(5):867-72.

PMID:
9635876
26.

Characterization of the cytochrome P450 CYP2J4: expression in rat small intestine and role in retinoic acid biotransformation from retinal.

Zhang QY, Raner G, Ding X, Dunbar D, Coon MJ, Kaminsky LS.

Arch Biochem Biophys. 1998 May 15;353(2):257-64.

PMID:
9606960
27.

Warfarin analog inhibition of human CYP2C9-catalyzed S-warfarin 7-hydroxylation.

Zhang ZY, Kerr J, Wexler RS, Li HY, Robinson AJ, Harlow PP, Kaminsky LS.

Thromb Res. 1997 Nov 15;88(4):389-98.

PMID:
9526963
28.

Inhibition of estrone sulfatase in human liver microsomes by quercetin and other flavonoids.

Huang Z, Fasco MJ, Kaminsky LS.

J Steroid Biochem Mol Biol. 1997 Sep-Oct;63(1-3):9-15.

PMID:
9449200
29.

The molecular epidemiology of lung cancer.

Spivack SD, Fasco MJ, Walker VE, Kaminsky LS.

Crit Rev Toxicol. 1997 Jul;27(4):319-65. Review.

PMID:
9263643
30.

Alternative splicing of CYP2D mRNA in human breast tissue.

Huang Z, Fasco MJ, Kaminsky LS.

Arch Biochem Biophys. 1997 Jul 1;343(1):101-8.

PMID:
9210651
31.

Comparisons of CYP2D messenger RNA splice variant profiles in human lung tumors and normal tissues.

Huang Z, Fasco MJ, Spivack S, Kaminsky LS.

Cancer Res. 1997 Jul 1;57(13):2589-92.

32.

CDNA cloning, heterologous expression, and characterization of rat intestinal CYP2J4.

Zhang QY, Ding X, Kaminsky LS.

Arch Biochem Biophys. 1997 Apr 15;340(2):270-8.

PMID:
9143331
33.

Human P450 metabolism of warfarin.

Kaminsky LS, Zhang ZY.

Pharmacol Ther. 1997;73(1):67-74. Review.

PMID:
9014207
34.
35.

The role of the CYP2C9-Leu359 allelic variant in the tolbutamide polymorphism.

Sullivan-Klose TH, Ghanayem BI, Bell DA, Zhang ZY, Kaminsky LS, Shenfield GM, Miners JO, Birkett DJ, Goldstein JA.

Pharmacogenetics. 1996 Aug;6(4):341-9.

PMID:
8873220
36.

Expression of cytochromes P450 in human breast tissue and tumors.

Huang Z, Fasco MJ, Figge HL, Keyomarsi K, Kaminsky LS.

Drug Metab Dispos. 1996 Aug;24(8):899-905.

PMID:
8869826
37.

Optimization of Dnase I removal of contaminating DNA from RNA for use in quantitative RNA-PCR.

Huang Z, Fasco MJ, Kaminsky LS.

Biotechniques. 1996 Jun;20(6):1012-4, 1016, 1018-20.

38.

Cytochrome P450 mRNA induction: quantitation by RNA-polymerase chain reaction using capillary electrophoresis.

Fasco MJ, Treanor C, Kaminsky LS.

Methods Enzymol. 1996;272:401-12. No abstract available.

PMID:
8791799
39.

Human cytochromes P4501A1 and P4501A2: R-warfarin metabolism as a probe.

Zhang Z, Fasco MJ, Huang Z, Guengerich FP, Kaminsky LS.

Drug Metab Dispos. 1995 Dec;23(12):1339-46.

PMID:
8689941
40.

Characterization of human cytochromes P450 involved in theophylline 8-hydroxylation.

Zhang ZY, Kaminsky LS.

Biochem Pharmacol. 1995 Jul 17;50(2):205-11.

PMID:
7632164
41.

Determination of theophylline and its metabolites in rat liver microsomes and human urine by capillary electrophoresis.

Zhang ZY, Fasco MJ, Kaminsky LS.

J Chromatogr B Biomed Appl. 1995 Mar 10;665(1):201-8.

PMID:
7795792
42.

Quantitative RNA-polymerase chain reaction-DNA analysis by capillary electrophoresis and laser-induced fluorescence.

Fasco MJ, Treanor CP, Spivack S, Figge HL, Kaminsky LS.

Anal Biochem. 1995 Jan 1;224(1):140-7.

PMID:
7710061
43.

Site-directed mutagenesis of putative substrate recognition sites in cytochrome P450 2B11: importance of amino acid residues 114, 290, and 363 for substrate specificity.

Hasler JA, Harlow GR, Szklarz GD, John GH, Kedzie KM, Burnett VL, He YA, Kaminsky LS, Halpert JR.

Mol Pharmacol. 1994 Aug;46(2):338-45.

PMID:
8078495
44.

Correlation of human cytochrome P4502C substrate specificities with primary structure: warfarin as a probe.

Kaminsky LS, de Morais SM, Faletto MB, Dunbar DA, Goldstein JA.

Mol Pharmacol. 1993 Feb;43(2):234-9.

PMID:
8429826
45.

Rat small intestinal cytochromes P450 probed by warfarin metabolism.

Fasco MJ, Silkworth JB, Dunbar DA, Kaminsky LS.

Mol Pharmacol. 1993 Feb;43(2):226-33.

PMID:
8429825
46.

Rat liver metabolism and toxicity of 2,2,2-trifluoroethanol.

Kaminsky LS, Fraser JM, Seaman M, Dunbar D.

Biochem Pharmacol. 1992 Nov 3;44(9):1829-37.

PMID:
1449537
47.

Azidowarfarin photoaffinity probes of purified rat liver cytochrome P4501A1.

Obach RS, Spink DC, Chen N, Kaminsky LS.

Arch Biochem Biophys. 1992 Apr;294(1):215-22.

PMID:
1550348
48.

17 beta-estradiol hydroxylation catalyzed by human cytochrome P450 1A1: a comparison of the activities induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin in MCF-7 cells with those from heterologous expression of the cDNA.

Spink DC, Eugster HP, Lincoln DW 2nd, Schuetz JD, Schuetz EG, Johnson JA, Kaminsky LS, Gierthy JF.

Arch Biochem Biophys. 1992 Mar;293(2):342-8.

PMID:
1536570
49.

Phase II metabolism of warfarin in primary culture of adult rat hepatocytes.

Jansing RL, Chao ES, Kaminsky LS.

Mol Pharmacol. 1992 Jan;41(1):209-15.

PMID:
1732719
50.

Fluoride: benefits and risks of exposure. The preparation of a report.

Kaminsky LS, Mahoney MC, Miller MJ.

J Am Coll Dent. 1992 Fall;59(3):4-7. No abstract available.

PMID:
1401581

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