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Scalable integration of nano-, and microfluidics with hybrid two-photon lithography.

Vanderpoorten O, Peter Q, Challa PK, Keyser UF, Baumberg J, Kaminski CF, Knowles TPJ.

Microsyst Nanoeng. 2019 Sep 9;5:40. doi: 10.1038/s41378-019-0080-3. eCollection 2019.


Super-condenser enables labelfree nanoscopy.

Ströhl F, Opstad IS, Tinguely JC, Dullo FT, Mela I, Osterrieth JWM, Ahluwalia BS, Kaminski CF.

Opt Express. 2019 Sep 2;27(18):25280-25292. doi: 10.1364/OE.27.025280.


Fast Fluorescence Lifetime Imaging Reveals the Aggregation Processes of α-Synuclein and Polyglutamine in Aging Caenorhabditis elegans.

Laine RF, Sinnige T, Ma KY, Haack AJ, Poudel C, Gaida P, Curry N, Perni M, Nollen EAA, Dobson CM, Vendruscolo M, Kaminski Schierle GS, Kaminski CF.

ACS Chem Biol. 2019 Jul 19;14(7):1628-1636. doi: 10.1021/acschembio.9b00354. Epub 2019 Jun 27.


Intrinsically aggregation-prone proteins form amyloid-like aggregates and contribute to tissue aging in Caenorhabditis elegans.

Huang C, Wagner-Valladolid S, Stephens AD, Jung R, Poudel C, Sinnige T, Lechler MC, Schlörit N, Lu M, Laine RF, Michel CH, Vendruscolo M, Kaminski CF, Kaminski Schierle GS, David DC.

Elife. 2019 May 3;8. pii: e43059. doi: 10.7554/eLife.43059.


A concept for single-shot volumetric fluorescence imaging via orthogonally polarized excitation lattices.

Ströhl F, Kaminski CF.

Sci Rep. 2019 Apr 23;9(1):6425. doi: 10.1038/s41598-019-42743-4.


Structured illumination microscopy combined with machine learning enables the high throughput analysis and classification of virus structure.

Laine RF, Goodfellow G, Young LJ, Travers J, Carroll D, Dibben O, Bright H, Kaminski CF.

Elife. 2018 Dec 13;7. pii: e40183. doi: 10.7554/eLife.40183.


Structural progression of amyloid-β Arctic mutant aggregation in cells revealed by multiparametric imaging.

Lu M, Williamson N, Mishra A, Michel CH, Kaminski CF, Tunnacliffe A, Kaminski Schierle GS.

J Biol Chem. 2019 Feb 1;294(5):1478-1487. doi: 10.1074/jbc.RA118.004511. Epub 2018 Nov 30.


Live-cell super-resolution microscopy reveals a primary role for diffusion in polyglutamine-driven aggresome assembly.

Lu M, Banetta L, Young LJ, Smith EJ, Bates GP, Zaccone A, Kaminski Schierle GS, Tunnacliffe A, Kaminski CF.

J Biol Chem. 2019 Jan 4;294(1):257-268. doi: 10.1074/jbc.RA118.003500. Epub 2018 Nov 6.


Single particle trajectories reveal active endoplasmic reticulum luminal flow.

Holcman D, Parutto P, Chambers JE, Fantham M, Young LJ, Marciniak SJ, Kaminski CF, Ron D, Avezov E.

Nat Cell Biol. 2018 Oct;20(10):1118-1125. doi: 10.1038/s41556-018-0192-2. Epub 2018 Sep 17.


Probing the Growth Kinetics for the Formation of Uniform 1D Block Copolymer Nanoparticles by Living Crystallization-Driven Self-Assembly.

Boott CE, Leitao EM, Hayward DW, Laine RF, Mahou P, Guerin G, Winnik MA, Richardson RM, Kaminski CF, Whittell GR, Manners I.

ACS Nano. 2018 Sep 25;12(9):8920-8933. doi: 10.1021/acsnano.8b01353. Epub 2018 Sep 12.


Opal-like Multicolor Appearance of Self-Assembled Photonic Array.

Arnon ZA, Pinotsi D, Schmidt M, Gilead S, Guterman T, Sadhanala A, Ahmad S, Levin A, Walther P, Kaminski CF, Fändrich M, Kaminski Schierle GS, Adler-Abramovich L, Shimon LJW, Gazit E.

ACS Appl Mater Interfaces. 2018 Jun 20;10(24):20783-20789. doi: 10.1021/acsami.8b04912. Epub 2018 Jun 7.


Different Structural Conformers of Monomeric α-Synuclein Identified after Lyophilizing and Freezing.

Stephens AD, Nespovitaya N, Zacharopoulou M, Kaminski CF, Phillips JJ, Kaminski Schierle GS.

Anal Chem. 2018 Jun 5;90(11):6975-6983. doi: 10.1021/acs.analchem.8b01264. Epub 2018 May 22.


FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-π Interactions.

Qamar S, Wang G, Randle SJ, Ruggeri FS, Varela JA, Lin JQ, Phillips EC, Miyashita A, Williams D, Ströhl F, Meadows W, Ferry R, Dardov VJ, Tartaglia GG, Farrer LA, Kaminski Schierle GS, Kaminski CF, Holt CE, Fraser PE, Schmitt-Ulms G, Klenerman D, Knowles T, Vendruscolo M, St George-Hyslop P.

Cell. 2018 Apr 19;173(3):720-734.e15. doi: 10.1016/j.cell.2018.03.056.


Computer-aided discovery of a metal-organic framework with superior oxygen uptake.

Moghadam PZ, Islamoglu T, Goswami S, Exley J, Fantham M, Kaminski CF, Snurr RQ, Farha OK, Fairen-Jimenez D.

Nat Commun. 2018 Apr 11;9(1):1378. doi: 10.1038/s41467-018-03892-8.


Flat-Field Super-Resolution Localization Microscopy with a Low-Cost Refractive Beam-Shaping Element.

Rowlands CJ, Ströhl F, Ramirez PPV, Scherer KM, Kaminski CF.

Sci Rep. 2018 Apr 4;8(1):5630. doi: 10.1038/s41598-018-24052-4.


C-terminal calcium binding of α-synuclein modulates synaptic vesicle interaction.

Lautenschläger J, Stephens AD, Fusco G, Ströhl F, Curry N, Zacharopoulou M, Michel CH, Laine R, Nespovitaya N, Fantham M, Pinotsi D, Zago W, Fraser P, Tandon A, St George-Hyslop P, Rees E, Phillips JJ, De Simone A, Kaminski CF, Schierle GSK.

Nat Commun. 2018 Feb 19;9(1):712. doi: 10.1038/s41467-018-03111-4.


Homographically generated light sheets for the microscopy of large specimens.

Russell CT, Rees EJ, Kaminski CF.

Opt Lett. 2018 Feb 15;43(4):663-666. doi: 10.1364/OL.43.000663.


Biophotonics of Native Silk Fibrils.

Shimanovich U, Pinotsi D, Shimanovich K, Yu N, Bolisetty S, Adamcik J, Mezzenga R, Charmet J, Vollrath F, Gazit E, Dobson CM, Schierle GK, Holland C, Kaminski CF, Knowles TPJ.

Macromol Biosci. 2018 Apr;18(4):e1700295. doi: 10.1002/mabi.201700295. Epub 2018 Jan 29.


Secondary nucleation of monomers on fibril surface dominates α-synuclein aggregation and provides autocatalytic amyloid amplification.

Gaspar R, Meisl G, Buell AK, Young L, Kaminski CF, Knowles TPJ, Sparr E, Linse S.

Q Rev Biophys. 2017 Jan;50:e6. doi: 10.1017/S0033583516000172.


Imaging Aβ(1-42) fibril elongation reveals strongly polarised growth and growth incompetent states.

Young LJ, Kaminski Schierle GS, Kaminski CF.

Phys Chem Chem Phys. 2017 Oct 25;19(41):27987-27996. doi: 10.1039/c7cp03412a.


Nanoscale click-reactive scaffolds from peptide self-assembly.

Guttenplan APM, Young LJ, Matak-Vinkovic D, Kaminski CF, Knowles TPJ, Itzhaki LS.

J Nanobiotechnology. 2017 Oct 6;15(1):70. doi: 10.1186/s12951-017-0300-7.


Speed limits of structured illumination microscopy.

Ströhl F, Kaminski CF.

Opt Lett. 2017 Jul 1;42(13):2511-2514. doi: 10.1364/OL.42.002511.


Total internal reflection fluorescence anisotropy imaging microscopy: setup, calibration, and data processing for protein polymerization measurements in living cells.

Ströhl F, Wong HHW, Holt CE, Kaminski CF.

Methods Appl Fluoresc. 2017 Dec 19;6(1):014004. doi: 10.1088/2050-6120/aa872e.


RNA Docking and Local Translation Regulate Site-Specific Axon Remodeling In Vivo.

Wong HH, Lin JQ, Ströhl F, Roque CG, Cioni JM, Cagnetta R, Turner-Bridger B, Laine RF, Harris WA, Kaminski CF, Holt CE.

Neuron. 2017 Aug 16;95(4):852-868.e8. doi: 10.1016/j.neuron.2017.07.016. Epub 2017 Aug 3.


Temperature Treatment of Highly Porous Zirconium-Containing Metal-Organic Frameworks Extends Drug Delivery Release.

Teplensky MH, Fantham M, Li P, Wang TC, Mehta JP, Young LJ, Moghadam PZ, Hupp JT, Farha OK, Kaminski CF, Fairen-Jimenez D.

J Am Chem Soc. 2017 Jun 7;139(22):7522-7532. doi: 10.1021/jacs.7b01451. Epub 2017 May 23.


Corrigendum: Structural basis of synaptic vesicle assembly promoted by α-synuclein.

Fusco G, Pape T, Stephens AD, Mahou P, Costa AR, Kaminski CF, Schierle GSK, Vendruscolo M, Veglia G, Dobson CM, De Simone A.

Nat Commun. 2017 May 11;8:15667. doi: 10.1038/ncomms15667. No abstract available.


Correlative STED and Atomic Force Microscopy on Live Astrocytes Reveals Plasticity of Cytoskeletal Structure and Membrane Physical Properties during Polarized Migration.

Curry N, Ghézali G, Kaminski Schierle GS, Rouach N, Kaminski CF.

Front Cell Neurosci. 2017 Apr 19;11:104. doi: 10.3389/fncel.2017.00104. eCollection 2017.


Acceleration of α-synuclein aggregation.

Gaspar R, Meisl G, Buell AK, Young L, Kaminski CF, Knowles TPJ, Sparr E, Linse S.

Amyloid. 2017 Mar;24(sup1):20-21. doi: 10.1080/13506129.2017.1292904. No abstract available.


Single Molecule Translation Imaging Visualizes the Dynamics of Local β-Actin Synthesis in Retinal Axons.

Ströhl F, Lin JQ, Laine RF, Wong HH, Urbančič V, Cagnetta R, Holt CE, Kaminski CF.

Sci Rep. 2017 Apr 6;7(1):709. doi: 10.1038/s41598-017-00695-7.


TriPer, an optical probe tuned to the endoplasmic reticulum tracks changes in luminal H2O2.

Melo EP, Lopes C, Gollwitzer P, Lortz S, Lenzen S, Mehmeti I, Kaminski CF, Ron D, Avezov E.

BMC Biol. 2017 Mar 27;15(1):24. doi: 10.1186/s12915-017-0367-5.


α-Synuclein - Regulator of Exocytosis, Endocytosis, or Both?

Lautenschläger J, Kaminski CF, Kaminski Schierle GS.

Trends Cell Biol. 2017 Jul;27(7):468-479. doi: 10.1016/j.tcb.2017.02.002. Epub 2017 Mar 2. Review.


Investigating State Restriction in Fluorescent Protein FRET Using Time-Resolved Fluorescence and Anisotropy.

Blacker TS, Chen W, Avezov E, Marsh RJ, Duchen MR, Kaminski CF, Bain AJ.

J Phys Chem C Nanomater Interfaces. 2017 Jan 26;121(3):1507-1514. doi: 10.1021/acs.jpcc.6b11235. Epub 2016 Dec 29.


Quantitative Affinity Determination by Fluorescence Anisotropy Measurements of Individual Nanoliter Droplets.

Gielen F, Butz M, Rees EJ, Erdelyi M, Moschetti T, Hyvönen M, Edel JB, Kaminski CF, Hollfelder F.

Anal Chem. 2017 Jan 17;89(2):1092-1101. doi: 10.1021/acs.analchem.6b02528. Epub 2017 Jan 3.


Super-resolution imaging of alpha-synuclein polymorphisms and their potential role in neurodegeneration.

Nugent E, Kaminski CF, Kaminski Schierle GS.

Integr Biol (Camb). 2017 Mar 1;9(3):206-210. doi: 10.1039/c6ib00206d. Epub 2017 Feb 9. Review.


Fluorescence Self-Quenching from Reporter Dyes Informs on the Structural Properties of Amyloid Clusters Formed in Vitro and in Cells.

Chen W, Young LJ, Lu M, Zaccone A, Ströhl F, Yu N, Kaminski Schierle GS, Kaminski CF.

Nano Lett. 2017 Jan 11;17(1):143-149. doi: 10.1021/acs.nanolett.6b03686. Epub 2016 Dec 8.


Heparin acts as a structural component of β-endorphin amyloid fibrils rather than a simple aggregation promoter.

Nespovitaya N, Mahou P, Laine RF, Schierle GSK, Kaminski CF.

Chem Commun (Camb). 2017 Jan 19;53(7):1273-1276. doi: 10.1039/c6cc09770g.


De novo design of a biologically active amyloid.

Gallardo R, Ramakers M, De Smet F, Claes F, Khodaparast L, Khodaparast L, Couceiro JR, Langenberg T, Siemons M, Nyström S, Young LJ, Laine RF, Young L, Radaelli E, Benilova I, Kumar M, Staes A, Desager M, Beerens M, Vandervoort P, Luttun A, Gevaert K, Bormans G, Dewerchin M, Van Eldere J, Carmeliet P, Vande Velde G, Verfaillie C, Kaminski CF, De Strooper B, Hammarström P, Nilsson KP, Serpell L, Schymkowitz J, Rousseau F.

Science. 2016 Nov 11;354(6313). pii: aah4949.


Structural basis of synaptic vesicle assembly promoted by α-synuclein.

Fusco G, Pape T, Stephens AD, Mahou P, Costa AR, Kaminski CF, Kaminski Schierle GS, Vendruscolo M, Veglia G, Dobson CM, De Simone A.

Nat Commun. 2016 Sep 19;7:12563. doi: 10.1038/ncomms12563.


Development of an open technology sensor suite for assisted living: a student-led research project.

Manton JD, Hughes JA, Bonner O, Amjad OA, Mair P, Miele I, Wang T, Levdik V, Hall RD, Baekelandt G, Vasconcellos Fda C, Hadeler O, Hutter T, Kaminski CF.

Interface Focus. 2016 Aug 6;6(4):20160018. doi: 10.1098/rsfs.2016.0018.


Probing amyloid protein aggregation with optical superresolution methods: from the test tube to models of disease.

Kaminski CF, Kaminski Schierle GS.

Neurophotonics. 2016 Oct;3(4):041807. doi: 10.1117/1.NPh.3.4.041807. Epub 2016 Jun 29.


From single-molecule spectroscopy to super-resolution imaging of the neuron: a review.

Laine RF, Kaminski Schierle GS, van de Linde S, Kaminski CF.

Methods Appl Fluoresc. 2016 Jun 27;4(2):022004. doi: 10.1088/2050-6120/4/2/022004. Review.


A Guide to Structured Illumination TIRF Microscopy at High Speed with Multiple Colors.

Young LJ, Ströhl F, Kaminski CF.

J Vis Exp. 2016 May 30;(111). doi: 10.3791/53988.


Nanoscopic insights into seeding mechanisms and toxicity of α-synuclein species in neurons.

Pinotsi D, Michel CH, Buell AK, Laine RF, Mahou P, Dobson CM, Kaminski CF, Kaminski Schierle GS.

Proc Natl Acad Sci U S A. 2016 Apr 5;113(14):3815-9. doi: 10.1073/pnas.1516546113. Epub 2016 Mar 18.


Proton Transfer and Structure-Specific Fluorescence in Hydrogen Bond-Rich Protein Structures.

Pinotsi D, Grisanti L, Mahou P, Gebauer R, Kaminski CF, Hassanali A, Kaminski Schierle GS.

J Am Chem Soc. 2016 Mar 9;138(9):3046-57. doi: 10.1021/jacs.5b11012. Epub 2016 Feb 25.


ALS/FTD Mutation-Induced Phase Transition of FUS Liquid Droplets and Reversible Hydrogels into Irreversible Hydrogels Impairs RNP Granule Function.

Murakami T, Qamar S, Lin JQ, Schierle GS, Rees E, Miyashita A, Costa AR, Dodd RB, Chan FT, Michel CH, Kronenberg-Versteeg D, Li Y, Yang SP, Wakutani Y, Meadows W, Ferry RR, Dong L, Tartaglia GG, Favrin G, Lin WL, Dickson DW, Zhen M, Ron D, Schmitt-Ulms G, Fraser PE, Shneider NA, Holt C, Vendruscolo M, Kaminski CF, St George-Hyslop P.

Neuron. 2015 Nov 18;88(4):678-90. doi: 10.1016/j.neuron.2015.10.030. Epub 2015 Oct 29.


In Situ Visualization of Block Copolymer Self-Assembly in Organic Media by Super-Resolution Fluorescence Microscopy.

Boott CE, Laine RF, Mahou P, Finnegan JR, Leitao EM, Webb SE, Kaminski CF, Manners I.

Chemistry. 2015 Dec 14;21(51):18539-42. doi: 10.1002/chem.201504100. Epub 2015 Nov 10.


HSV-1 Glycoproteins Are Delivered to Virus Assembly Sites Through Dynamin-Dependent Endocytosis.

Albecka A, Laine RF, Janssen AF, Kaminski CF, Crump CM.

Traffic. 2016 Jan;17(1):21-39. doi: 10.1111/tra.12340. Epub 2015 Nov 6.


Fast and simple spectral FLIM for biochemical and medical imaging.

Popleteeva M, Haas KT, Stoppa D, Pancheri L, Gasparini L, Kaminski CF, Cassidy LD, Venkitaraman AR, Esposito A.

Opt Express. 2015 Sep 7;23(18):23511-25. doi: 10.1364/OE.23.023511.


Super-resolution fluorescent methods: where next for super-resolution?

Knight A, Kaminski CF, Sauer M.

Methods Appl Fluoresc. 2015 Aug 13;3(3):030201. doi: 10.1088/2050-6120/3/3/030201. No abstract available.


Optical Super-Resolution Imaging of β-Amyloid Aggregation In Vitro and In Vivo: Method and Techniques.

Pinotsi D, Kaminski Schierle GS, Kaminski CF.

Methods Mol Biol. 2016;1303:125-41. doi: 10.1007/978-1-4939-2627-5_6.


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