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Items: 38

1.

Insulin activates intracellular transport of lipid droplets to release triglycerides from the liver.

Kumar M, Ojha S, Rai P, Joshi A, Kamat SS, Mallik R.

J Cell Biol. 2019 Nov 4;218(11):3697-3713. doi: 10.1083/jcb.201903102. Epub 2019 Oct 11.

PMID:
31604801
2.

Functional Annotation of ABHD14B, an Orphan Serine Hydrolase Enzyme.

Rajendran A, Vaidya K, Mendoza J, Bridwell-Rabb J, Kamat SS.

Biochemistry. 2019 Sep 13. doi: 10.1021/acs.biochem.9b00703. [Epub ahead of print]

PMID:
31478652
3.

Chemoproteomics of an Indole-Based Quinone Epoxide Identifies Druggable Vulnerabilities in Vancomycin-Resistant Staphylococcus aureus.

Kulkarni A, Soni I, Kelkar DS, Dharmaraja AT, Sankar RK, Beniwal G, Rajendran A, Tamhankar S, Chopra S, Kamat SS, Chakrapani H.

J Med Chem. 2019 Jul 25;62(14):6785-6795. doi: 10.1021/acs.jmedchem.9b00774. Epub 2019 Jul 15.

4.

Pterostilbene reverses palmitic acid mediated insulin resistance in HepG2 cells by reducing oxidative stress and triglyceride accumulation.

Malik SA, Acharya JD, Mehendale NK, Kamat SS, Ghaskadbi SS.

Free Radic Res. 2019 Jul;53(7):815-827. doi: 10.1080/10715762.2019.1635252. Epub 2019 Jul 10.

PMID:
31223033
5.

A chemical-genetic screen identifies ABHD12 as an oxidized-phosphatidylserine lipase.

Kelkar DS, Ravikumar G, Mehendale N, Singh S, Joshi A, Sharma AK, Mhetre A, Rajendran A, Chakrapani H, Kamat SS.

Nat Chem Biol. 2019 Feb;15(2):169-178. doi: 10.1038/s41589-018-0195-0. Epub 2019 Jan 14.

6.

Integrating Patient Education Into the Glaucoma Clinical Encounter: A Lean Analysis.

Newman-Casey PA, Musser JA, Niziol LM, Heisler MM, Kamat SS, Shah MM, Patel N, Cohn AM.

J Glaucoma. 2019 May;28(5):415-422. doi: 10.1097/IJG.0000000000001192.

PMID:
30640805
7.

SOD1 activity threshold and TOR signalling modulate VAP(P58S) aggregation via reactive oxygen species-induced proteasomal degradation in a Drosophila model of amyotrophic lateral sclerosis.

Chaplot K, Pimpale L, Ramalingam B, Deivasigamani S, Kamat SS, Ratnaparkhi GS.

Dis Model Mech. 2019 Feb 7;12(2). pii: dmm033803. doi: 10.1242/dmm.033803.

8.

Drosophila DNA/RNA methyltransferase contributes to robust host defense in aging animals by regulating sphingolipid metabolism.

Abhyankar V, Kaduskar B, Kamat SS, Deobagkar D, Ratnaparkhi GS.

J Exp Biol. 2018 Nov 16;221(Pt 22). pii: jeb187989. doi: 10.1242/jeb.187989.

9.

Biochemical characterization of the PHARC-associated serine hydrolase ABHD12 reveals its preference for very-long-chain lipids.

Joshi A, Shaikh M, Singh S, Rajendran A, Mhetre A, Kamat SS.

J Biol Chem. 2018 Nov 2;293(44):16953-16963. doi: 10.1074/jbc.RA118.005640. Epub 2018 Sep 20.

10.

Lipidomics Suggests a New Role for Ceramide Synthase in Phagocytosis.

Pathak D, Mehendale N, Singh S, Mallik R, Kamat SS.

ACS Chem Biol. 2018 Aug 17;13(8):2280-2287. doi: 10.1021/acschembio.8b00438. Epub 2018 Jul 13.

11.

Methylphosphonic Acid Biosynthesis and Catabolism in Pelagic Archaea and Bacteria.

Ulrich EC, Kamat SS, Hove-Jensen B, Zechel DL.

Methods Enzymol. 2018;605:351-426. doi: 10.1016/bs.mie.2018.01.039. Epub 2018 May 3. Review.

PMID:
29909833
12.

Kinesin-dependent mechanism for controlling triglyceride secretion from the liver.

Rai P, Kumar M, Sharma G, Barak P, Das S, Kamat SS, Mallik R.

Proc Natl Acad Sci U S A. 2017 Dec 5;114(49):12958-12963. doi: 10.1073/pnas.1713292114. Epub 2017 Nov 20.

13.

The Ability of Nitric Oxide to Lower Intraocular Pressure Is Dependent on Guanylyl Cyclase.

Muenster S, Lieb WS, Fabry G, Allen KN, Kamat SS, Guy AH, Dordea AC, Teixeira L, Tainsh RE, Yu B, Zhu W, Ashpole NE, Malhotra R, Brouckaert P, Bloch DB, Scherrer-Crosbie M, Stamer WD, Kuehn MH, Pasquale LR, Buys ES.

Invest Ophthalmol Vis Sci. 2017 Sep 1;58(11):4826-4835. doi: 10.1167/iovs.17-22168.

14.

Mice lacking lipid droplet-associated hydrolase, a gene linked to human prostate cancer, have normal cholesterol ester metabolism.

Kory N, Grond S, Kamat SS, Li Z, Krahmer N, Chitraju C, Zhou P, Fröhlich F, Semova I, Ejsing C, Zechner R, Cravatt BF, Farese RV Jr, Walther TC.

J Lipid Res. 2017 Jan;58(1):226-235. doi: 10.1194/jlr.M072538. Epub 2016 Nov 11.

15.

Branched Fatty Acid Esters of Hydroxy Fatty Acids Are Preferred Substrates of the MODY8 Protein Carboxyl Ester Lipase.

Kolar MJ, Kamat SS, Parsons WH, Homan EA, Maher T, Peroni OD, Syed I, Fjeld K, Molven A, Kahn BB, Cravatt BF, Saghatelian A.

Biochemistry. 2016 Aug 23;55(33):4636-41. doi: 10.1021/acs.biochem.6b00565. Epub 2016 Aug 10.

16.

A calcium-dependent acyltransferase that produces N-acyl phosphatidylethanolamines.

Ogura Y, Parsons WH, Kamat SS, Cravatt BF.

Nat Chem Biol. 2016 Sep;12(9):669-71. doi: 10.1038/nchembio.2127. Epub 2016 Jul 11.

17.

AIG1 and ADTRP are atypical integral membrane hydrolases that degrade bioactive FAHFAs.

Parsons WH, Kolar MJ, Kamat SS, Cognetta AB 3rd, Hulce JJ, Saez E, Kahn BB, Saghatelian A, Cravatt BF.

Nat Chem Biol. 2016 May;12(5):367-372. doi: 10.1038/nchembio.2051. Epub 2016 Mar 28.

18.

The Role of the Immune System in Glaucoma: Bridging the Divide Between Immune Mechanisms in Experimental Glaucoma and the Human Disease.

Kamat SS, Gregory MS, Pasquale LR.

Semin Ophthalmol. 2016;31(1-2):147-54. doi: 10.3109/08820538.2015.1114858. Review.

PMID:
26959140
19.

Immunomodulatory lysophosphatidylserines are regulated by ABHD16A and ABHD12 interplay.

Kamat SS, Camara K, Parsons WH, Chen DH, Dix MM, Bird TD, Howell AR, Cravatt BF.

Nat Chem Biol. 2015 Feb;11(2):164-71. doi: 10.1038/nchembio.1721. Epub 2015 Jan 12.

20.

Combining cross-metathesis and activity-based protein profiling: new β-lactone motifs for targeting serine hydrolases.

Camara K, Kamat SS, Lasota CC, Cravatt BF, Howell AR.

Bioorg Med Chem Lett. 2015 Jan 15;25(2):317-21. doi: 10.1016/j.bmcl.2014.11.038.

21.

Functional annotation and structural characterization of a novel lactonase hydrolyzing D-xylono-1,4-lactone-5-phosphate and L-arabino-1,4-lactone-5-phosphate.

Korczynska M, Xiang DF, Zhang Z, Xu C, Narindoshvili T, Kamat SS, Williams HJ, Chang SS, Kolb P, Hillerich B, Sauder JM, Burley SK, Almo SC, Swaminathan S, Shoichet BK, Raushel FM.

Biochemistry. 2014 Jul 22;53(28):4727-38. doi: 10.1021/bi500595c. Epub 2014 Jul 9.

22.

Focal cortical dysplasias in autism spectrum disorders.

Casanova MF, El-Baz AS, Kamat SS, Dombroski BA, Khalifa F, Elnakib A, Soliman A, Allison-McNutt A, Switala AE.

Acta Neuropathol Commun. 2013 Oct 11;1:67. doi: 10.1186/2051-5960-1-67.

23.

Potent inhibition of the C-P lyase nucleosidase PhnI by Immucillin-A triphosphate.

Kamat SS, Burgos ES, Raushel FM.

Biochemistry. 2013 Oct 22;52(42):7366-8. doi: 10.1021/bi4013287. Epub 2013 Oct 11.

24.

Immunohistochemical analysis of syndecan-1 in leukoplakia and oral submucous fibrosis.

Kamat SS, Kumar GS, Koshy AV.

Dent Res J (Isfahan). 2013 May;10(3):321-7.

25.

The enzymatic conversion of phosphonates to phosphate by bacteria.

Kamat SS, Raushel FM.

Curr Opin Chem Biol. 2013 Aug;17(4):589-96. doi: 10.1016/j.cbpa.2013.06.006. Epub 2013 Jul 2. Review.

PMID:
23830682
26.

The catalytic mechanism for aerobic formation of methane by bacteria.

Kamat SS, Williams HJ, Dangott LJ, Chakrabarti M, Raushel FM.

Nature. 2013 May 2;497(7447):132-6. doi: 10.1038/nature12061. Epub 2013 Apr 24.

PMID:
23615610
27.

Expression of extracellular matrix-laminin in oral squamous cell carcinoma: an immunohistochemical study.

Koshy AV, Rao NN, Kamat SS, Kiswani K, Kapse SC, Shaikh NA.

J Contemp Dent Pract. 2012 Mar 1;13(2):194-200.

PMID:
22665747
28.

Intermediates in the transformation of phosphonates to phosphate by bacteria.

Kamat SS, Williams HJ, Raushel FM.

Nature. 2011 Nov 16;480(7378):570-3. doi: 10.1038/nature10622.

29.

The catalase activity of diiron adenine deaminase.

Kamat SS, Holmes-Hampton GP, Bagaria A, Kumaran D, Tichy SE, Gheyi T, Zheng X, Bain K, Groshong C, Emtage S, Sauder JM, Burley SK, Swaminathan S, Lindahl PA, Raushel FM.

Protein Sci. 2011 Dec;20(12):2080-94. doi: 10.1002/pro.748. Epub 2011 Nov 9.

30.

Enzymatic deamination of the epigenetic base N-6-methyladenine.

Kamat SS, Fan H, Sauder JM, Burley SK, Shoichet BK, Sali A, Raushel FM.

J Am Chem Soc. 2011 Feb 23;133(7):2080-3. doi: 10.1021/ja110157u. Epub 2011 Jan 28.

31.

Catalytic mechanism and three-dimensional structure of adenine deaminase.

Kamat SS, Bagaria A, Kumaran D, Holmes-Hampton GP, Fan H, Sali A, Sauder JM, Burley SK, Lindahl PA, Swaminathan S, Raushel FM.

Biochemistry. 2011 Mar 22;50(11):1917-27. doi: 10.1021/bi101788n. Epub 2011 Feb 4.

32.

Simultaneous determination of hydrochlorothiazide, quinapril and quinaprilat in human plasma by liquid chromatography-tandem mass spectrometry.

Parekh SA, Pudage A, Joshi SS, Vaidya VV, Gomes NA, Kamat SS.

J Chromatogr B Analyt Technol Biomed Life Sci. 2008 Sep 15;873(1):59-69. doi: 10.1016/j.jchromb.2008.07.046. Epub 2008 Aug 7.

PMID:
18723407
33.

Triplets with systemic lupus erythematosus.

Kamat SS, Pepmueller PH, Moore TL.

Arthritis Rheum. 2003 Nov;48(11):3176-80.

34.

Permanent maxillary central incisor impaction: report of two cases.

Kamat SS, Kumar GS, Raghunath V, Rekha KP.

Quintessence Int. 2003 Jan;34(1):50-2.

PMID:
12674359
35.

Colorimetric method for determination of ethanol in presence of methanol.

Sane RT, Kamat SS, Pandit AD.

J Assoc Off Anal Chem. 1981 Sep;64(5):1145-8.

PMID:
7287611
36.

Colorimetric determination of endrin in biological materials.

Sane RT, Kamat SS.

Forensic Sci Int. 1981 Jul-Aug;18(1):63-6. No abstract available.

PMID:
7250869
37.

2-Thiobarbituric acid as a reagent for the detection of meconic acid by thin-layer chromatography.

Kamat SS, Joglekar VD.

J Chromatogr. 1975 Jul 2;110(1):190-2. No abstract available.

PMID:
1133144
38.

Amino-acid synthesis from hydrogen cyanide under possible primitive earth conditions.

ORO J, KAMAT SS.

Nature. 1961 Apr 29;190:442-3. No abstract available.

PMID:
13731262

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