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Items: 36

1.

Eldecalcitol is more effective in promoting osteogenesis than alfacalcidol in Cyp27b1-knockout mice.

Hirota Y, Nakagawa K, Isomoto K, Sakaki T, Kubodera N, Kamao M, Osakabe N, Suhara Y, Okano T.

PLoS One. 2018 Oct 3;13(10):e0199856. doi: 10.1371/journal.pone.0199856. eCollection 2018.

2.

Determination of Menadione by Liquid Chromatography-Tandem Mass Spectrometry Using Pseudo Multiple Reaction Monitoring.

Kamao M, Hirota Y, Suhara Y, Tsugawa N, Nakagawa K, Okano T, Hasegawa H.

Anal Sci. 2017;33(7):863-867. doi: 10.2116/analsci.33.863.

3.

Nongenomic effects of 1α,25-dihydroxyvitamin D3 on cartilage formation deduced from comparisons between Cyp27b1 and Vdr knockout mice.

Hirota Y, Nakagawa K, Mimatsu S, Sawada N, Sakaki T, Kubodera N, Kamao M, Tsugawa N, Suhara Y, Okano T.

Biochem Biophys Res Commun. 2017 Jan 29;483(1):359-365. doi: 10.1016/j.bbrc.2016.12.139. Epub 2016 Dec 24.

4.

Association between vitamin D status and serum parathyroid hormone concentration and calcaneal stiffness in Japanese adolescents: sex differences in susceptibility to vitamin D deficiency.

Tsugawa N, Uenishi K, Ishida H, Ozaki R, Takase T, Minekami T, Uchino Y, Kamao M, Okano T.

J Bone Miner Metab. 2016 Jul;34(4):464-74. doi: 10.1007/s00774-015-0694-y. Epub 2015 Aug 12.

PMID:
26260151
5.

Functional characterization of the vitamin K2 biosynthetic enzyme UBIAD1.

Hirota Y, Nakagawa K, Sawada N, Okuda N, Suhara Y, Uchino Y, Kimoto T, Funahashi N, Kamao M, Tsugawa N, Okano T.

PLoS One. 2015 Apr 15;10(4):e0125737. doi: 10.1371/journal.pone.0125737. eCollection 2015.

6.

Vitamin K2 biosynthetic enzyme, UBIAD1 is essential for embryonic development of mice.

Nakagawa K, Sawada N, Hirota Y, Uchino Y, Suhara Y, Hasegawa T, Amizuka N, Okamoto T, Tsugawa N, Kamao M, Funahashi N, Okano T.

PLoS One. 2014 Aug 15;9(8):e104078. doi: 10.1371/journal.pone.0104078. eCollection 2014.

7.

Menadione (vitamin K3) is a catabolic product of oral phylloquinone (vitamin K1) in the intestine and a circulating precursor of tissue menaquinone-4 (vitamin K2) in rats.

Hirota Y, Tsugawa N, Nakagawa K, Suhara Y, Tanaka K, Uchino Y, Takeuchi A, Sawada N, Kamao M, Wada A, Okitsu T, Okano T.

J Biol Chem. 2013 Nov 15;288(46):33071-80. doi: 10.1074/jbc.M113.477356. Epub 2013 Sep 30.

8.

A novel method based on curvature analysis for estimating the dietary vitamin K requirement in adolescents.

Tsugawa N, Uenishi K, Ishida H, Minekami T, Doi A, Koike S, Takase T, Kamao M, Mimura Y, Okano T.

Clin Nutr. 2012 Apr;31(2):255-60. doi: 10.1016/j.clnu.2011.10.006. Epub 2011 Nov 9.

PMID:
22078785
9.

High prevalence of hypovitaminosis D and K in patients with hip fracture.

Nakano T, Tsugawa N, Kuwabara A, Kamao M, Tanaka K, Okano T.

Asia Pac J Clin Nutr. 2011;20(1):56-61.

10.

Hypovitaminosis D and K are highly prevalent and independent of overall malnutrition in the institutionalized elderly.

Kuwabara A, Himeno M, Tsugawa N, Kamao M, Fujii M, Kawai N, Fukuda M, Ogawa Y, Kido S, Okano T, Tanaka K.

Asia Pac J Clin Nutr. 2010;19(1):49-56.

11.

[In vivo metabolism of vitamin K: in relation to the conversion of vitamin K1 to MK-4].

Okano T, Nakagawa K, Kamao M.

Clin Calcium. 2009 Dec;19(12):1779-87. doi: CliCa091217791787. Review. Japanese.

PMID:
19949269
12.

High prevalence of vitamin K and D deficiency and decreased BMD in inflammatory bowel disease.

Kuwabara A, Tanaka K, Tsugawa N, Nakase H, Tsuji H, Shide K, Kamao M, Chiba T, Inagaki N, Okano T, Kido S.

Osteoporos Int. 2009 Jun;20(6):935-42. doi: 10.1007/s00198-008-0764-2. Epub 2008 Sep 30.

PMID:
18825300
13.

Vitamin K content of foods and dietary vitamin K intake in Japanese young women.

Kamao M, Suhara Y, Tsugawa N, Uwano M, Yamaguchi N, Uenishi K, Ishida H, Sasaki S, Okano T.

J Nutr Sci Vitaminol (Tokyo). 2007 Dec;53(6):464-70.

14.

Design and synthesis of biologically active analogues of vitamin K2: evaluation of their biological activities with cultured human cell lines.

Suhara Y, Hirota Y, Nakagawa K, Kamao M, Tsugawa N, Okano T.

Bioorg Med Chem. 2008 Mar 15;16(6):3108-17. doi: 10.1016/j.bmc.2007.12.025. Epub 2008 Jan 2.

PMID:
18171617
15.

Low plasma phylloquinone concentration is associated with high incidence of vertebral fracture in Japanese women.

Tsugawa N, Shiraki M, Suhara Y, Kamao M, Ozaki R, Tanaka K, Okano T.

J Bone Miner Metab. 2008;26(1):79-85. Epub 2008 Jan 10.

PMID:
18095068
16.

Conversion of phylloquinone (Vitamin K1) into menaquinone-4 (Vitamin K2) in mice: two possible routes for menaquinone-4 accumulation in cerebra of mice.

Okano T, Shimomura Y, Yamane M, Suhara Y, Kamao M, Sugiura M, Nakagawa K.

J Biol Chem. 2008 Apr 25;283(17):11270-9. Epub 2007 Dec 14.

17.

Nutritional effects of gamma-glutamyl carboxylase gene polymorphism on the correlation between the vitamin K status and gamma-carboxylation of osteocalcin in young males.

Sogabe N, Tsugawa N, Maruyama R, Kamao M, Kinoshita H, Okano T, Hosoi T, Goseki-Sone M.

J Nutr Sci Vitaminol (Tokyo). 2007 Oct;53(5):419-25.

18.

Quantification of fat-soluble vitamins in human breast milk by liquid chromatography-tandem mass spectrometry.

Kamao M, Tsugawa N, Suhara Y, Wada A, Mori T, Murata K, Nishino R, Ukita T, Uenishi K, Tanaka K, Okano T.

J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Nov 15;859(2):192-200. Epub 2007 Oct 17.

PMID:
17942378
19.

Efficient synthesis and biological evaluation of omega-oxygenated analogues of vitamin K2: study of modification and structure-activity relationship of vitamin K2 metabolites.

Suhara Y, Murakami A, Kamao M, Mimatsu S, Nakagawa K, Tsugawa N, Okano T.

Bioorg Med Chem Lett. 2007 Mar 15;17(6):1622-5. Epub 2007 Jan 4.

PMID:
17239598
20.

Vitamin K status of healthy Japanese women: age-related vitamin K requirement for gamma-carboxylation of osteocalcin.

Tsugawa N, Shiraki M, Suhara Y, Kamao M, Tanaka K, Okano T.

Am J Clin Nutr. 2006 Feb;83(2):380-6.

PMID:
16469998
21.
22.

Measurement and characterization of C-3 epimerization activity toward vitamin D3.

Kamao M, Hatakeyama S, Sakaki T, Sawada N, Inouye K, Kubodera N, Reddy GS, Okano T.

Arch Biochem Biophys. 2005 Apr 1;436(1):196-205.

PMID:
15752725
23.
24.

Determination of plasma Vitamin K by high-performance liquid chromatography with fluorescence detection using Vitamin K analogs as internal standards.

Kamao M, Suhara Y, Tsugawa N, Okano T.

J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Feb 25;816(1-2):41-8.

PMID:
15664332
25.

Sequential metabolism of 2,3,7-trichlorodibenzo-p-dioxin (2,3,7-triCDD) by cytochrome P450 and UDP-glucuronosyltransferase in human liver microsomes.

Kasai N, Sakaki T, Shinkyo R, Ikushiro S, Iyanagi T, Kamao M, Okano T, Ohta M, Inouye K.

Drug Metab Dispos. 2004 Aug;32(8):870-5.

PMID:
15258113
26.

Cell specificity and properties of the C-3 epimerization of Vitamin D3 metabolites.

Kamao M, Tatematsu S, Sawada N, Sakaki T, Hatakeyama S, Kubodera N, Okano T.

J Steroid Biochem Mol Biol. 2004 May;89-90(1-5):39-42.

PMID:
15225744
27.

Novel metabolism of 1 alpha,25-dihydroxyvitamin D3 with C24-C25 bond cleavage catalyzed by human CYP24A1.

Sawada N, Kusudo T, Sakaki T, Hatakeyama S, Hanada M, Abe D, Kamao M, Okano T, Ohta M, Inouye K.

Biochemistry. 2004 Apr 20;43(15):4530-7.

PMID:
15078099
28.

C-3 epimerization of vitamin D3 metabolites and further metabolism of C-3 epimers: 25-hydroxyvitamin D3 is metabolized to 3-epi-25-hydroxyvitamin D3 and subsequently metabolized through C-1alpha or C-24 hydroxylation.

Kamao M, Tatematsu S, Hatakeyama S, Sakaki T, Sawada N, Inouye K, Ozono K, Kubodera N, Reddy GS, Okano T.

J Biol Chem. 2004 Apr 16;279(16):15897-907. Epub 2004 Feb 2.

29.

Two novel metabolic pathways of 22-oxacalcitriol (OCT). C-25 dehydration and C-3 epimerization and biological activities of novel OCT metabolites.

Kamao M, Tatematsu S, Hatakeyama S, Ozono K, Kubodera N, Reddy GS, Okano T.

J Biol Chem. 2003 Jan 17;278(3):1463-71. Epub 2002 Nov 1.

30.

Isolation, identification and biological activity of 24R,25-dihydroxy-3-epi-vitamin D3: a novel metabolite of 24R,25-dihydroxyvitamin D3 produced in rat osteosarcoma cells (UMR 106).

Kamao M, Tatematsu S, Reddy GS, Hatakeyama S, Sugiura M, Ohashi N, Kubodera N, Okano T.

J Nutr Sci Vitaminol (Tokyo). 2001 Apr;47(2):108-15.

PMID:
11508700
31.

Absorption of calcium, magnesium, phosphorus, iron and zinc in growing male rats fed diets containing either phytate-free soybean protein or soybean protein isolate or casein.

Kamao M, Tsugawa N, Nakagawa K, Kawamoto Y, Fukui K, Takamatsu K, Kuwata G, Imai M, Okano T.

J Nutr Sci Vitaminol (Tokyo). 2000 Feb;46(1):34-41.

PMID:
10868351
32.

Hyperparathyroidism is augmented by ovariectomy in Nagase analbuminemic rats.

Inaba M, Morii H, Katsumata T, Goto H, Ishimura E, Kawagishi T, Kamao M, Okano T, Nishizawa Y.

J Nutr. 2000 Jun;130(6):1543-7.

PMID:
10827207
33.

Characterization of 3-epi-1alpha,25-dihydroxyvitamin D3 involved in 1alpha,25-dihydroxyvitamin D3 metabolic pathway in cultured cell lines.

Masuda S, Kamao M, Schroeder NJ, Makin HL, Jones G, Kremer R, Rhim J, Okano T.

Biol Pharm Bull. 2000 Feb;23(2):133-9.

PMID:
10706373
34.

Absorbability of calcium from a new calcium supplement prepared from bovine marrow-free bone in rats.

Ohtani M, Tsugawa N, Kamao M, Okano T.

J Nutr Sci Vitaminol (Tokyo). 1998 Dec;44(6):887-95.

PMID:
10197319
35.

Intestinal absorption of calcium from calcium ascorbate in rats.

Tsugawa N, Yamabe T, Takeuchi A, Kamao M, Nakagawa K, Nishijima K, Okano T.

J Bone Miner Metab. 1999;17(1):30-6.

PMID:
10084399
36.

A novel high-performance liquid chromatographic assay for vitamin D metabolites using a coulometric electrochemical detector.

Masuda S, Okano T, Kamao M, Kanedai Y, Kobayashi T.

J Pharm Biomed Anal. 1997 Jun;15(9-10):1497-502.

PMID:
9226581

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