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Profiling surface proteins on individual exosomes using a proximity barcoding assay.

Wu D, Yan J, Shen X, Sun Y, Thulin M, Cai Y, Wik L, Shen Q, Oelrich J, Qian X, Dubois KL, Ronquist KG, Nilsson M, Landegren U, Kamali-Moghaddam M.

Nat Commun. 2019 Aug 26;10(1):3854. doi: 10.1038/s41467-019-11486-1.


Reduced sialyl-Lewisx on salivary MUC7 from patients with burning mouth syndrome.

Acharya S, Jin C, Bylund J, Shen Q, Kamali-Moghaddam M, Jontell M, Carlén A, Karlsson NG.

Mol Omics. 2019 Oct 7;15(5):331-339. doi: 10.1039/c9mo00061e.


Multiplex plasma protein profiling identifies novel markers to discriminate patients with adenocarcinoma of the lung.

Djureinovic D, Pontén V, Landelius P, Al Sayegh S, Kappert K, Kamali-Moghaddam M, Micke P, Ståhle E.

BMC Cancer. 2019 Jul 29;19(1):741. doi: 10.1186/s12885-019-5943-3.


Sensitive and Specific Detection of Platelet-Derived and Tissue Factor-Positive Extracellular Vesicles in Plasma Using Solid-Phase Proximity Ligation Assay.

Thulin Å, Yan J, Åberg M, Christersson C, Kamali-Moghaddam M, Siegbahn A.

TH Open. 2018 Jul 27;2(3):e250-e260. doi: 10.1055/s-0038-1667204. eCollection 2018 Jul.


A targeted proteomics approach reveals a serum protein signature as diagnostic biomarker for resectable gastric cancer.

Shen Q, Polom K, Williams C, de Oliveira FMS, Guergova-Kuras M, Lisacek F, Karlsson NG, Roviello F, Kamali-Moghaddam M.

EBioMedicine. 2019 Jun;44:322-333. doi: 10.1016/j.ebiom.2019.05.044. Epub 2019 May 28.


Monitoring of Protein Biomarkers of Inflammation in Human Traumatic Brain Injury Using Microdialysis and Proximity Extension Assay Technology in Neurointensive Care.

Dyhrfort P, Shen Q, Clausen F, Thulin M, Enblad P, Kamali-Moghaddam M, Lewén A, Hillered L.

J Neurotrauma. 2019 Oct 15;36(20):2872-2885. doi: 10.1089/neu.2018.6320. Epub 2019 Jun 17.


Next wave advances in single-cell analyses.

Herr AE, Kitamori T, Landegren U, Kamali-Moghaddam M.

Analyst. 2019 Jan 28;144(3):735-737. doi: 10.1039/c9an90011j. No abstract available.


Protein measurements in venous plasma, earlobe capillary plasma and in plasma stored on filter paper.

Siart B, de Oliveira FMS, Shen Q, Björkesten J, Pekar T, Steinborn R, Nimmerichter A, Kamali-Moghaddam M, Wallner B.

Anal Biochem. 2019 Feb 1;566:146-150. doi: 10.1016/j.ab.2018.11.016. Epub 2018 Nov 22.


Protein profiling of fine-needle aspirates reveals subtype-associated immune signatures and involvement of chemokines in breast cancer.

Franzén B, Alexeyenko A, Kamali-Moghaddam M, Hatschek T, Kanter L, Ramqvist T, Kierkegaard J, Masucci G, Auer G, Landegren U, Lewensohn R.

Mol Oncol. 2019 Feb;13(2):376-391. doi: 10.1002/1878-0261.12410. Epub 2019 Jan 7.


Protein Profiling in Serum and Cerebrospinal Fluid Following Complex Surgery on the Thoracic Aorta Identifies Biological Markers of Neurologic Injury.

Lindblom RPF, Shen Q, Axén S, Landegren U, Kamali-Moghaddam M, Thelin S.

J Cardiovasc Transl Res. 2018 Dec;11(6):503-516. doi: 10.1007/s12265-018-9835-8. Epub 2018 Oct 26.


Inflammatory markers in women with postpartum depressive symptoms.

Bränn E, Fransson E, White RA, Papadopoulos FC, Edvinsson Å, Kamali-Moghaddam M, Cunningham JL, Sundström-Poromaa I, Skalkidou A.

J Neurosci Res. 2018 Sep 5. doi: 10.1002/jnr.24312. [Epub ahead of print]


Ibrutinib induces rapid down-regulation of inflammatory markers and altered transcription of chronic lymphocytic leukaemia-related genes in blood and lymph nodes.

Palma M, Krstic A, Peña Perez L, Berglöf A, Meinke S, Wang Q, Blomberg KEM, Kamali-Moghaddam M, Shen Q, Jaremko G, Lundin J, De Paepe A, Höglund P, Kimby E, Österborg A, Månsson R, Smith CIE.

Br J Haematol. 2018 Oct;183(2):212-224. doi: 10.1111/bjh.15516. Epub 2018 Aug 20.


A fine-needle aspiration-based protein signature discriminates benign from malignant breast lesions.

Franzén B, Kamali-Moghaddam M, Alexeyenko A, Hatschek T, Becker S, Wik L, Kierkegaard J, Eriksson A, Muppani NR, Auer G, Landegren U, Lewensohn R.

Mol Oncol. 2018 Sep;12(9):1415-1428. doi: 10.1002/1878-0261.12350. Epub 2018 Aug 9.


Plasma Protein Profiling Reveal Osteoprotegerin as a Marker of Prognostic Impact for Colorectal Cancer.

Birgisson H, Tsimogiannis K, Freyhult E, Kamali-Moghaddam M.

Transl Oncol. 2018 Aug;11(4):1034-1043. doi: 10.1016/j.tranon.2018.05.012. Epub 2018 Jul 4.


GABA Regulates Release of Inflammatory Cytokines From Peripheral Blood Mononuclear Cells and CD4+ T Cells and Is Immunosuppressive in Type 1 Diabetes.

Bhandage AK, Jin Z, Korol SV, Shen Q, Pei Y, Deng Q, Espes D, Carlsson PO, Kamali-Moghaddam M, Birnir B.

EBioMedicine. 2018 Apr;30:283-294. doi: 10.1016/j.ebiom.2018.03.019. Epub 2018 Mar 28.


Detection of post-translational modifications using solid-phase proximity ligation assay.

Oliveira FMS, Mereiter S, Lönn P, Siart B, Shen Q, Heldin J, Raykova D, Karlsson NG, Polom K, Roviello F, Reis CA, Kamali-Moghaddam M.

N Biotechnol. 2018 Oct 25;45:51-59. doi: 10.1016/j.nbt.2017.10.005. Epub 2017 Oct 31.


Strong impact on plasma protein profiles by precentrifugation delay but not by repeated freeze-thaw cycles, as analyzed using multiplex proximity extension assays.

Shen Q, Björkesten J, Galli J, Ekman D, Broberg J, Nordberg N, Tillander A, Kamali-Moghaddam M, Tybring G, Landegren U.

Clin Chem Lab Med. 2018 Mar 28;56(4):582-594. doi: 10.1515/cclm-2017-0648.


Lubricin binds cartilage proteins, cartilage oligomeric matrix protein, fibronectin and collagen II at the cartilage surface.

Flowers SA, Zieba A, Örnros J, Jin C, Rolfson O, Björkman LI, Eisler T, Kalamajski S, Kamali-Moghaddam M, Karlsson NG.

Sci Rep. 2017 Oct 13;7(1):13149. doi: 10.1038/s41598-017-13558-y.


Tracing Cellular Origin of Human Exosomes Using Multiplex Proximity Extension Assays.

Larssen P, Wik L, Czarnewski P, Eldh M, Löf L, Ronquist KG, Dubois L, Freyhult E, Gallant CJ, Oelrich J, Larsson A, Ronquist G, Villablanca EJ, Landegren U, Gabrielsson S, Kamali-Moghaddam M.

Mol Cell Proteomics. 2017 Aug;16(8):1547. doi: 10.1074/mcp.A116.064725. No abstract available.


Detection of Extracellular Vesicles Using Proximity Ligation Assay with Flow Cytometry Readout-ExoPLA.

Löf L, Arngården L, Ebai T, Landegren U, Söderberg O, Kamali-Moghaddam M.

Curr Protoc Cytom. 2017 Jul 5;81:4.8.1-4.8.10. doi: 10.1002/cpcy.22.


Analytically Sensitive Protein Detection in Microtiter Plates by Proximity Ligation with Rolling Circle Amplification.

Ebai T, Souza de Oliveira FM, Löf L, Wik L, Schweiger C, Larsson A, Keilholtz U, Haybaeck J, Landegren U, Kamali-Moghaddam M.

Clin Chem. 2017 Sep;63(9):1497-1505. doi: 10.1373/clinchem.2017.271833. Epub 2017 Jun 30.


Stability of Proteins in Dried Blood Spot Biobanks.

Björkesten J, Enroth S, Shen Q, Wik L, Hougaard DM, Cohen AS, Sörensen L, Giedraitis V, Ingelsson M, Larsson A, Kamali-Moghaddam M, Landegren U.

Mol Cell Proteomics. 2017 Jul;16(7):1286-1296. doi: 10.1074/mcp.RA117.000015. Epub 2017 May 13.


Highly sensitive and specific protein detection via combined capillary isoelectric focusing and proximity ligation.

Padhan N, Yan J, Boge A, Scrivener E, Birgisson H, Zieba A, Gullberg M, Kamali-Moghaddam M, Claesson-Welsh L, Landegren U.

Sci Rep. 2017 May 4;7(1):1490. doi: 10.1038/s41598-017-01516-7.


Flow Cytometric Measurement of Blood Cells with BCR-ABL1 Fusion Protein in Chronic Myeloid Leukemia.

Löf L, Arngården L, Olsson-Strömberg U, Siart B, Jansson M, Dahlin JS, Thörn I, Christiansson L, Hermansson M, Larsson A, Ahlstrand E, Wålinder G, Söderberg O, Rosenquist R, Landegren U, Kamali-Moghaddam M.

Sci Rep. 2017 Apr 4;7(1):623. doi: 10.1038/s41598-017-00755-y.


Lower inflammatory markers in women with antenatal depression brings the M1/M2 balance into focus from a new direction.

Edvinsson Å, Bränn E, Hellgren C, Freyhult E, White R, Kamali-Moghaddam M, Olivier J, Bergquist J, Boström AE, Schiöth HB, Skalkidou A, Cunningham JL, Sundström-Poromaa I.

Psychoneuroendocrinology. 2017 Jun;80:15-25. doi: 10.1016/j.psyneuen.2017.02.027. Epub 2017 Feb 28.


Inflammatory markers in late pregnancy in association with postpartum depression-A nested case-control study.

Bränn E, Papadopoulos F, Fransson E, White R, Edvinsson Å, Hellgren C, Kamali-Moghaddam M, Boström A, Schiöth HB, Sundström-Poromaa I, Skalkidou A.

Psychoneuroendocrinology. 2017 May;79:146-159. doi: 10.1016/j.psyneuen.2017.02.029. Epub 2017 Feb 28.


Tracing Cellular Origin of Human Exosomes Using Multiplex Proximity Extension Assays.

Larssen P, Wik L, Czarnewski P, Eldh M, Löf L, Ronquist KG, Dubois L, Freyhult E, Gallant CJ, Oelrich J, Larsson A, Ronquist G, Villablanca EJ, Landegren U, Gabrielsson S, Kamali-Moghaddam M.

Mol Cell Proteomics. 2017 Mar;16(3):502-511. doi: 10.1074/mcp.M116.064725. Epub 2017 Jan 22. Erratum in: Mol Cell Proteomics. 2017 Aug;16(8):1547.


Detecting individual extracellular vesicles using a multicolor in situ proximity ligation assay with flow cytometric readout.

Löf L, Ebai T, Dubois L, Wik L, Ronquist KG, Nolander O, Lundin E, Söderberg O, Landegren U, Kamali-Moghaddam M.

Sci Rep. 2016 Sep 29;6:34358. doi: 10.1038/srep34358.


Inflammatory Serum Protein Profiling of Patients with Lumbar Radicular Pain One Year after Disc Herniation.

Moen A, Lind AL, Thulin M, Kamali-Moghaddam M, Røe C, Gjerstad J, Gordh T.

Int J Inflam. 2016;2016:3874964. doi: 10.1155/2016/3874964. Epub 2016 May 11.


Elevated Levels of SOX10 in Serum from Vitiligo and Melanoma Patients, Analyzed by Proximity Ligation Assay.

Blokzijl A, Chen LE, Gustafsdottir SM, Vuu J, Ullenhag G, Kämpe O, Landegren U, Kamali-Moghaddam M, Hedstrand H.

PLoS One. 2016 Apr 25;11(4):e0154214. doi: 10.1371/journal.pone.0154214. eCollection 2016.


A Multiplex Protein Panel Applied to Cerebrospinal Fluid Reveals Three New Biomarker Candidates in ALS but None in Neuropathic Pain Patients.

Lind AL, Wu D, Freyhult E, Bodolea C, Ekegren T, Larsson A, Gustafsson MG, Katila L, Bergquist J, Gordh T, Landegren U, Kamali-Moghaddam M.

PLoS One. 2016 Feb 25;11(2):e0149821. doi: 10.1371/journal.pone.0149821. eCollection 2016.


Preparation, characterisation and thermal properties of calcium alginate/n-nonadecane microcapsules fabricated by electro-coextrusion for thermo-regulating textiles.

Kamali Moghaddam M, Mortazavi SM.

J Microencapsul. 2015;32(8):737-44. doi: 10.3109/02652048.2015.1073388. Epub 2015 Aug 21.


The body mass index (BMI) is significantly correlated with levels of cytokines and chemokines in cerebrospinal fluid.

Larsson A, Carlsson L, Lind AL, Gordh T, Bodolea C, Kamali-Moghaddam M, Thulin M.

Cytokine. 2015 Dec;76(2):514-518. doi: 10.1016/j.cyto.2015.07.010. Epub 2015 Jul 15.


The effects of age and gender on plasma levels of 63 cytokines.

Larsson A, Carlsson L, Gordh T, Lind AL, Thulin M, Kamali-Moghaddam M.

J Immunol Methods. 2015 Oct;425:58-61. doi: 10.1016/j.jim.2015.06.009. Epub 2015 Jun 14.


Elevated Serum GAD65 and GAD65-GADA Immune Complexes in Stiff Person Syndrome.

Gu Urban GJ, Friedman M, Ren P, Törn C, Fex M, Hampe CS, Lernmark Å, Landegren U, Kamali-Moghaddam M.

Sci Rep. 2015 Jun 16;5:11196. doi: 10.1038/srep11196.


Proximity-dependent initiation of hybridization chain reaction.

Koos B, Cane G, Grannas K, Löf L, Arngården L, Heldin J, Clausson CM, Klaesson A, Hirvonen MK, de Oliveira FM, Talibov VO, Pham NT, Auer M, Danielson UH, Haybaeck J, Kamali-Moghaddam M, Söderberg O.

Nat Commun. 2015 Jun 12;6:7294. doi: 10.1038/ncomms8294.


Corrigendum: solid-phase proximity ligation assays for individual or parallel protein analyses with readout via real-time PCR or sequencing.

Nong RY, Wu D, Yan J, Hammond M, Gu GJ, Kamali-Moghaddam M, Landegren U, Darmanis S.

Nat Protoc. 2015 Apr;10(4):643. doi: 10.1038/nprot0415-644b. Epub 2015 Mar 26. No abstract available.


Next-generation pathology--surveillance of tumor microecology.

Koos B, Kamali-Moghaddam M, David L, Sobrinho-Simões M, Dimberg A, Nilsson M, Wählby C, Söderberg O.

J Mol Biol. 2015 Jun 5;427(11):2013-22. doi: 10.1016/j.jmb.2015.02.017. Epub 2015 Feb 26. Review.


Parallel protein detection by solid-phase proximity ligation assay with real-time PCR or sequencing.

Ebai T, Kamali-Moghaddam M, Landegren U.

Curr Protoc Mol Biol. 2015 Jan 5;109:20.10.1-25. doi: 10.1002/0471142727.mb2010s109.


Sensitive detection of aggregated prion protein via proximity ligation.

Hammond M, Wik L, Deslys JP, Comoy E, Linné T, Landegren U, Kamali-Moghaddam M.

Prion. 2014;8(3):261-5. doi: 10.4161/pri.32231.


A universal approach to prepare reagents for DNA-assisted protein analysis.

Yan J, Gu GJ, Jost C, Hammond M, Plückthun A, Landegren U, Kamali-Moghaddam M.

PLoS One. 2014 Sep 18;9(9):e108061. doi: 10.1371/journal.pone.0108061. eCollection 2014.


Tyrosine phosphorylation profiling via in situ proximity ligation assay.

Elfineh L, Classon C, Asplund A, Pettersson U, Kamali-Moghaddam M, Lind SB.

BMC Cancer. 2014 Jun 13;14:435. doi: 10.1186/1471-2407-14-435.


Protein biomarker validation via proximity ligation assays.

Blokzijl A, Nong R, Darmanis S, Hertz E, Landegren U, Kamali-Moghaddam M.

Biochim Biophys Acta. 2014 May;1844(5):933-9. doi: 10.1016/j.bbapap.2013.07.016. Epub 2013 Aug 7. Review.


A tosyl-activated magnetic bead cellulose as solid support for sensitive protein detection.

Yan J, Horák D, Lenfeld J, Hammond M, Kamali-Moghaddam M.

J Biotechnol. 2013 Sep 10;167(3):235-40. doi: 10.1016/j.jbiotec.2013.06.010. Epub 2013 Jun 27.


Solid-phase proximity ligation assays for individual or parallel protein analyses with readout via real-time PCR or sequencing.

Nong RY, Wu D, Yan J, Hammond M, Gu GJ, Kamali-Moghaddam M, Landegren U, Darmanis S.

Nat Protoc. 2013 Jun;8(6):1234-48. doi: 10.1038/nprot.2013.070. Epub 2013 May 30. Erratum in: Nat Protoc. 2015 Apr;10(4):643.


Role of individual MARK isoforms in phosphorylation of tau at Ser²⁶² in Alzheimer's disease.

Gu GJ, Lund H, Wu D, Blokzijl A, Classon C, von Euler G, Landegren U, Sunnemark D, Kamali-Moghaddam M.

Neuromolecular Med. 2013 Sep;15(3):458-69. doi: 10.1007/s12017-013-8232-3. Epub 2013 May 12.


Dynamic gradients of an intermediate filament-like cytoskeleton are recruited by a polarity landmark during apical growth.

Fuchino K, Bagchi S, Cantlay S, Sandblad L, Wu D, Bergman J, Kamali-Moghaddam M, Flärdh K, Ausmees N.

Proc Natl Acad Sci U S A. 2013 May 21;110(21):E1889-97. doi: 10.1073/pnas.1305358110. Epub 2013 May 2.


Multiplex protein detection with DNA readout via mass spectrometry.

Flanigon J, Kamali-Moghaddam M, Burbulis I, Annink C, Steffen M, Oeth P, Brent R, van den Boom D, Landegren U, Cantor C.

N Biotechnol. 2013 Jan 25;30(2):153-8. doi: 10.1016/j.nbt.2012.11.003. Epub 2012 Nov 28.


Elevated MARK2-dependent phosphorylation of Tau in Alzheimer's disease.

Gu GJ, Wu D, Lund H, Sunnemark D, Kvist AJ, Milner R, Eckersley S, Nilsson LN, Agerman K, Landegren U, Kamali-Moghaddam M.

J Alzheimers Dis. 2013;33(3):699-713. doi: 10.3233/JAD-2012-121357.


Erlin-2 is associated with active γ-secretase in brain and affects amyloid β-peptide production.

Teranishi Y, Hur JY, Gu GJ, Kihara T, Ishikawa T, Nishimura T, Winblad B, Behbahani H, Kamali-Moghaddam M, Frykman S, Tjernberg LO.

Biochem Biophys Res Commun. 2012 Aug 3;424(3):476-81. doi: 10.1016/j.bbrc.2012.06.137. Epub 2012 Jul 4.


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