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Improving the Quality of Synthetic FLAIR Images with Deep Learning Using a Conditional Generative Adversarial Network for Pixel-by-Pixel Image Translation.

Hagiwara A, Otsuka Y, Hori M, Tachibana Y, Yokoyama K, Fujita S, Andica C, Kamagata K, Irie R, Koshino S, Maekawa T, Chougar L, Wada A, Takemura MY, Hattori N, Aoki S.

AJNR Am J Neuroradiol. 2019 Jan 10. doi: 10.3174/ajnr.A5927. [Epub ahead of print]


Choroid plexus cysts analyzed using diffusion-weighted imaging with short diffusion-time.

Maekawa T, Hori M, Murata K, Feiweier T, Andica C, Fukunaga I, Koshino S, Hagiwara A, Kamiya K, Kamagata K, Wada A, Abe O, Aoki S.

Magn Reson Imaging. 2019 Apr;57:323-327. doi: 10.1016/j.mri.2018.12.010. Epub 2018 Dec 31.


Effect of Gadolinium on the Estimation of Myelin and Brain Tissue Volumes Based on Quantitative Synthetic MRI.

Maekawa T, Hagiwara A, Hori M, Andica C, Haruyama T, Kuramochi M, Nakazawa M, Koshino S, Irie R, Kamagata K, Wada A, Abe O, Aoki S.

AJNR Am J Neuroradiol. 2018 Dec 27. doi: 10.3174/ajnr.A5921. [Epub ahead of print]


A Comparison of Techniques for Correcting Eddy-current and Motion-induced Distortions in Diffusion-weighted Echo-planar Images.

Haneda J, Hagiwara A, Hori M, Wada A, Fukunaga I, Murata K, Kamagata K, Fujita S, Maekawa T, Irie R, Takamura T, Suzuki M, Kunishima Kumamaru K, Aoki S.

Magn Reson Med Sci. 2018 Dec 3. doi: 10.2463/ [Epub ahead of print]


Differentiating Alzheimer's Disease from Dementia with Lewy Bodies Using a Deep Learning Technique Based on Structural Brain Connectivity.

Wada A, Tsuruta K, Irie R, Kamagata K, Maekawa T, Fujita S, Koshino S, Kumamaru K, Suzuki M, Nakanishi A, Hori M, Aoki S.

Magn Reson Med Sci. 2018 Dec 3. doi: 10.2463/ [Epub ahead of print]


Linearity, Bias, Intrascanner Repeatability, and Interscanner Reproducibility of Quantitative Multidynamic Multiecho Sequence for Rapid Simultaneous Relaxometry at 3 T: A Validation Study With a Standardized Phantom and Healthy Controls.

Hagiwara A, Hori M, Cohen-Adad J, Nakazawa M, Suzuki Y, Kasahara A, Horita M, Haruyama T, Andica C, Maekawa T, Kamagata K, Kumamaru KK, Abe O, Aoki S.

Invest Radiol. 2019 Jan;54(1):39-47. doi: 10.1097/RLI.0000000000000510.


Myelin Measurement: Comparison Between Simultaneous Tissue Relaxometry, Magnetization Transfer Saturation Index, and T1w/T2w Ratio Methods.

Hagiwara A, Hori M, Kamagata K, Warntjes M, Matsuyoshi D, Nakazawa M, Ueda R, Andica C, Koshino S, Maekawa T, Irie R, Takamura T, Kumamaru KK, Abe O, Aoki S.

Sci Rep. 2018 Jul 12;8(1):10554. doi: 10.1038/s41598-018-28852-6.


Intrinsically disordered domain of tumor suppressor p53 facilitates target search by ultrafast transfer between different DNA strands.

Itoh Y, Murata A, Takahashi S, Kamagata K.

Nucleic Acids Res. 2018 Aug 21;46(14):7261-7269. doi: 10.1093/nar/gky586.


Neuromelanin imaging and midbrain volumetry in progressive supranuclear palsy and Parkinson's disease.

Taniguchi D, Hatano T, Kamagata K, Okuzumi A, Oji Y, Mori A, Hori M, Aoki S, Hattori N.

Mov Disord. 2018 Sep;33(9):1488-1492. doi: 10.1002/mds.27365. Epub 2018 May 14.


Changes in the ADC of diffusion-weighted MRI with the oscillating gradient spin-echo (OGSE) sequence due to differences in substrate viscosities.

Maekawa T, Hori M, Murata K, Feiweier T, Fukunaga I, Andica C, Hagiwara A, Kamagata K, Koshino S, Abe O, Aoki S.

Jpn J Radiol. 2018 Jul;36(7):415-420. doi: 10.1007/s11604-018-0737-0. Epub 2018 Apr 26.


Application of Quantitative Microstructural MR Imaging with Atlas-based Analysis for the Spinal Cord in Cervical Spondylotic Myelopathy.

Hori M, Hagiwara A, Fukunaga I, Ueda R, Kamiya K, Suzuki Y, Liu W, Murata K, Takamura T, Hamasaki N, Irie R, Kamagata K, Kumamaru KK, Suzuki M, Aoki S.

Sci Rep. 2018 Mar 26;8(1):5213. doi: 10.1038/s41598-018-23527-8.


Neurite orientation dispersion and density imaging of the nigrostriatal pathway in Parkinson's disease: Retrograde degeneration observed by tract-profile analysis.

Andica C, Kamagata K, Hatano T, Okuzumi A, Saito A, Nakazawa M, Ueda R, Motoi Y, Kamiya K, Suzuki M, Hori M, Kumamaru KK, Hattori N, Aoki S.

Parkinsonism Relat Disord. 2018 Jun;51:55-60. doi: 10.1016/j.parkreldis.2018.02.046. Epub 2018 Feb 28.


Dopamine transporter imaging predicts motor responsiveness to levodopa challenge in patients with Parkinson's disease: A pilot study of DATSCAN for subthalamic deep brain stimulation.

Nakajima A, Shimo Y, Sekimoto S, Kamagata K, Jo T, Oyama G, Umemura A, Hattori N.

J Neurol Sci. 2018 Feb 15;385:134-139. doi: 10.1016/j.jns.2017.12.030. Epub 2017 Dec 27.


Combining Segmented Grey and White Matter Images Improves Voxel-based Morphometry for the Case of Dilated Lateral Ventricles.

Goto M, Abe O, Aoki S, Kamagata K, Hori M, Miyati T, Gomi T, Takeda T.

Magn Reson Med Sci. 2018 Oct 10;17(4):293-300. doi: 10.2463/ Epub 2018 Jan 18.


High Free-Energy Barrier of 1D Diffusion Along DNA by Architectural DNA-Binding Proteins.

Kamagata K, Mano E, Ouchi K, Kanbayashi S, Johnson RC.

J Mol Biol. 2018 Mar 2;430(5):655-667. doi: 10.1016/j.jmb.2018.01.001. Epub 2018 Jan 4.


The Advantage of Synthetic MRI for the Visualization of Anterior Temporal Pole Lesions on Double Inversion Recovery (DIR), Phase-sensitive Inversion Recovery (PSIR), and Myelin Images in a Patient with CADASIL.

Wallaert L, Hagiwara A, Andica C, Hori M, Yamashiro K, Koshino S, Maekawa T, Kamagata K, Aoki S.

Magn Reson Med Sci. 2018 Oct 10;17(4):275-276. doi: 10.2463/ Epub 2017 Dec 12. No abstract available.


The Relationship between Neurite Density Measured with Confocal Microscopy in a Cleared Mouse Brain and Metrics Obtained from Diffusion Tensor and Diffusion Kurtosis Imaging.

Irie R, Kamagata K, Kerever A, Ueda R, Yokosawa S, Otake Y, Ochi H, Yoshizawa H, Hayashi A, Tagawa K, Okazawa H, Takahashi K, Sato K, Hori M, Arikawa-Hirasawa E, Aoki S.

Magn Reson Med Sci. 2018 Apr 10;17(2):138-144. doi: 10.2463/ Epub 2017 Dec 7.


Connectome analysis with diffusion MRI in idiopathic Parkinson's disease: Evaluation using multi-shell, multi-tissue, constrained spherical deconvolution.

Kamagata K, Zalesky A, Hatano T, Di Biase MA, El Samad O, Saiki S, Shimoji K, Kumamaru KK, Kamiya K, Hori M, Hattori N, Aoki S, Pantelis C.

Neuroimage Clin. 2017 Nov 10;17:518-529. doi: 10.1016/j.nicl.2017.11.007. eCollection 2018.


Automated brain tissue and myelin volumetry based on quantitative MR imaging with various in-plane resolutions.

Andica C, Hagiwara A, Hori M, Nakazawa M, Goto M, Koshino S, Kamagata K, Kumamaru KK, Aoki S.

J Neuroradiol. 2018 May;45(3):164-168. doi: 10.1016/j.neurad.2017.10.002. Epub 2017 Nov 11.


Spatial Restriction within Intracranial Epidermoid Cysts Observed Using Short Diffusion-time Diffusion-weighted Imaging.

Andica C, Hori M, Kamiya K, Koshino S, Hagiwara A, Kamagata K, Fukunaga I, Hamasaki N, Suzuki M, Feiweier T, Murata K, Arakawa A, Kondo A, Akiyama O, Aoki S.

Magn Reson Med Sci. 2018 Jul 10;17(3):269-272. doi: 10.2463/ Epub 2017 Nov 13.


Slice-accelerated gradient-echo echo planar imaging dynamic susceptibility contrast-enhanced MRI with blipped CAIPI: effect of increasing temporal resolution.

Takamura T, Hori M, Kamagata K, Kumamaru KK, Irie R, Hagiwara A, Hamasaki N, Aoki S.

Jpn J Radiol. 2018 Jan;36(1):40-50. doi: 10.1007/s11604-017-0695-y. Epub 2017 Oct 31.


Radiologist involvement is associated with reduced use of MRI in the acute period of low back pain in a non-elderly population.

Kumamaru KK, Sano Y, Kumamaru H, Hori M, Takamura T, Irie R, Suzuki M, Hagiwara A, Kamagata K, Nakanishi A, Aoki S.

Eur Radiol. 2018 Apr;28(4):1600-1608. doi: 10.1007/s00330-017-5086-3. Epub 2017 Oct 23.


The Disordered Linker in p53 Participates in Nonspecific Binding to and One-Dimensional Sliding along DNA Revealed by Single-Molecule Fluorescence Measurements.

Subekti DRG, Murata A, Itoh Y, Fukuchi S, Takahashi H, Kanbayashi S, Takahashi S, Kamagata K.

Biochemistry. 2017 Aug 15;56(32):4134-4144. doi: 10.1021/acs.biochem.7b00292. Epub 2017 Aug 3.


Depressive symptoms in Parkinson's disease are related to decreased left hippocampal volume: correlation with the 15-item shortened version of the Geriatric Depression Scale.

Goto M, Kamagata K, Hatano T, Hattori N, Abe O, Aoki S, Hori M, Gomi T.

Acta Radiol. 2018 Mar;59(3):341-345. doi: 10.1177/0284185117719100. Epub 2017 Jul 10.


One-Dimensional Search Dynamics of Tumor Suppressor p53 Regulated by a Disordered C-Terminal Domain.

Murata A, Itoh Y, Mano E, Kanbayashi S, Igarashi C, Takahashi H, Takahashi S, Kamagata K.

Biophys J. 2017 Jun 6;112(11):2301-2314. doi: 10.1016/j.bpj.2017.04.038.


Understanding microstructure of the brain by comparison of neurite orientation dispersion and density imaging (NODDI) with transparent mouse brain.

Sato K, Kerever A, Kamagata K, Tsuruta K, Irie R, Tagawa K, Okazawa H, Arikawa-Hirasawa E, Nitta N, Aoki I, Aoki S.

Acta Radiol Open. 2017 Apr 17;6(4):2058460117703816. doi: 10.1177/2058460117703816. eCollection 2017 Apr.


Gray Matter Abnormalities in Idiopathic Parkinson's Disease: Evaluation by Diffusional Kurtosis Imaging and Neurite Orientation Dispersion and Density Imaging.

Kamagata K, Zalesky A, Hatano T, Ueda R, Di Biase MA, Okuzumi A, Shimoji K, Hori M, Caeyenberghs K, Pantelis C, Hattori N, Aoki S.

Hum Brain Mapp. 2017 May 4. doi: 10.1002/hbm.23628. [Epub ahead of print]


Probing native metal ion association sites through quenching of fluorophores in the nucleotide-binding domains of the ABC transporter MsbA.

Tatsumi D, Nanatani K, Koike Y, Kamagata K, Takahashi S, Konno A, Furuta T, Sakurai M, Uozumi N.

Biochem J. 2017 May 30;474(12):1993-2007. doi: 10.1042/BCJ20161051.


Diffusion imaging of reversible and irreversible microstructural changes within the corticospinal tract in idiopathic normal pressure hydrocephalus.

Kamiya K, Hori M, Irie R, Miyajima M, Nakajima M, Kamagata K, Tsuruta K, Saito A, Nakazawa M, Suzuki Y, Mori H, Kunimatsu A, Arai H, Aoki S, Abe O.

Neuroimage Clin. 2017 Mar 11;14:663-671. doi: 10.1016/j.nicl.2017.03.003. eCollection 2017.


Erratum to: Diagnostic imaging of dementia with Lewy bodies by susceptibility-weighted imaging of nigrosomes versus striatal dopamine transporter single-photon emission computed tomography: a retrospective observational study.

Kamagata K, Nakatsuka T, Sakakibara R, Tsuyusaki Y, Takamura T, Sato K, Suzuki M, Hori M, Kumamaru KK, Inaoka T, Aoki S, Terada H.

Neuroradiology. 2017 Apr;59(4):425. doi: 10.1007/s00234-017-1814-2. No abstract available.


Neuromelanin MRI is useful for monitoring motor complications in Parkinson's and PARK2 disease.

Hatano T, Okuzumi A, Kamagata K, Daida K, Taniguchi D, Hori M, Yoshino H, Aoki S, Hattori N.

J Neural Transm (Vienna). 2017 Apr;124(4):407-415. doi: 10.1007/s00702-017-1688-9. Epub 2017 Feb 3.


Diagnostic imaging of dementia with Lewy bodies by susceptibility-weighted imaging of nigrosomes versus striatal dopamine transporter single-photon emission computed tomography: a retrospective observational study.

Kamagata K, Nakatsuka T, Sakakibara R, Tsuyusaki Y, Takamura T, Sato K, Suzuki M, Hori M, Kumamaru KK, Inaoka T, Aoki S, Terada H.

Neuroradiology. 2017 Jan;59(1):89-98. doi: 10.1007/s00234-016-1773-z. Epub 2016 Dec 29. Erratum in: Neuroradiology. 2017 Apr;59(4):425.


Usefulness of Non-Contrast-Enhanced MR Angiography Using a Silent Scan for Follow-Up after Y-Configuration Stent-Assisted Coil Embolization for Basilar Tip Aneurysms.

Takano N, Suzuki M, Irie R, Yamamoto M, Hamasaki N, Kamagata K, Kumamaru KK, Hori M, Oishi H, Aoki S.

AJNR Am J Neuroradiol. 2017 Mar;38(3):577-581. doi: 10.3174/ajnr.A5033. Epub 2016 Dec 22.


Synthetic MRI in the Detection of Multiple Sclerosis Plaques.

Hagiwara A, Hori M, Yokoyama K, Takemura MY, Andica C, Tabata T, Kamagata K, Suzuki M, Kumamaru KK, Nakazawa M, Takano N, Kawasaki H, Hamasaki N, Kunimatsu A, Aoki S.

AJNR Am J Neuroradiol. 2017 Feb;38(2):257-263. doi: 10.3174/ajnr.A5012. Epub 2016 Dec 8.


Neurite orientation dispersion and density imaging for evaluation of corticospinal tract in idiopathic normal pressure hydrocephalus.

Irie R, Tsuruta K, Hori M, Suzuki M, Kamagata K, Nakanishi A, Kamiya K, Nakajima M, Miyajima M, Arai H, Aoki S.

Jpn J Radiol. 2017 Jan;35(1):25-30. doi: 10.1007/s11604-016-0594-7. Epub 2016 Oct 27.


Pathways Linked to Internuclear Ophthalmoplegia on Diffusion-Tensor Imaging in a Case with Midbrain Infarction.

Takeshige H, Ueno Y, Kamagata K, Sasaki F, Yamashiro K, Tanaka R, Aoki S, Hattori N.

J Stroke Cerebrovasc Dis. 2016 Nov;25(11):2575-2579. doi: 10.1016/j.jstrokecerebrovasdis.2016.06.040. Epub 2016 Aug 24.


Activation of p53 Facilitates the Target Search in DNA by Enhancing the Target Recognition Probability.

Itoh Y, Murata A, Sakamoto S, Nanatani K, Wada T, Takahashi S, Kamagata K.

J Mol Biol. 2016 Jul 17;428(14):2916-30. doi: 10.1016/j.jmb.2016.06.001. Epub 2016 Jun 9.


Alterations of the optic pathway between unilateral and bilateral optic nerve damage in multiple sclerosis as revealed by the combined use of advanced diffusion kurtosis imaging and visual evoked potentials.

Takemura MY, Hori M, Yokoyama K, Hamasaki N, Suzuki M, Kamagata K, Kamiya K, Suzuki Y, Kyogoku S, Masutani Y, Hattori N, Aoki S.

Magn Reson Imaging. 2017 Jun;39:24-30. doi: 10.1016/j.mri.2016.04.011. Epub 2016 Apr 21.


A strategy to optimize radiation exposure for non-contrast head CT: comparison with the Japanese diagnostic reference levels.

Kumamaru KK, Kogure Y, Suzuki M, Hori M, Nakanishi A, Kamagata K, Hagiwara A, Andica C, Ri K, Houshido N, Aoki S.

Jpn J Radiol. 2016 Jun;34(6):451-7. doi: 10.1007/s11604-016-0545-3. Epub 2016 Apr 20.


Quantitative Histological Validation of Diffusion Tensor MRI with Two-Photon Microscopy of Cleared Mouse Brain.

Kamagata K, Kerever A, Yokosawa S, Otake Y, Ochi H, Hori M, Kamiya K, Tsuruta K, Tagawa K, Okazawa H, Aoki S, Arikawa-Hirasawa E.

Magn Reson Med Sci. 2016 Oct 11;15(4):416-421. Epub 2016 Mar 30. No abstract available.


Diffusional Kurtosis Imaging in Idiopathic Normal Pressure Hydrocephalus: Correlation with Severity of Cognitive Impairment.

Kamiya K, Kamagata K, Miyajima M, Nakajima M, Hori M, Tsuruta K, Mori H, Kunimatsu A, Arai H, Aoki S, Ohtomo K.

Magn Reson Med Sci. 2016 Jul 11;15(3):316-23. doi: 10.2463/ Epub 2016 Feb 3.


What is NODDI and what is its role in Parkinson's assessment?

Kamagata K, Hatano T, Aoki S.

Expert Rev Neurother. 2016;16(3):241-3. doi: 10.1586/14737175.2016.1142876. Epub 2016 Feb 6. No abstract available.


Prospective estimation of mean axon diameter and extra-axonal space of the posterior limb of the internal capsule in patients with idiopathic normal pressure hydrocephalus before and after a lumboperitoneal shunt by using q-space diffusion MRI.

Hori M, Kamiya K, Nakanishi A, Fukunaga I, Miyajima M, Nakajima M, Suzuki M, Suzuki Y, Irie R, Kamagata K, Arai H, Aoki S.

Eur Radiol. 2016 Sep;26(9):2992-8. doi: 10.1007/s00330-015-4162-9. Epub 2015 Dec 22.


Where the complex things are: single molecule and ensemble spectroscopic investigations of protein folding dynamics.

Takahashi S, Kamagata K, Oikawa H.

Curr Opin Struct Biol. 2016 Feb;36:1-9. doi: 10.1016/ Epub 2015 Dec 11. Review.


Neurite orientation dispersion and density imaging in the substantia nigra in idiopathic Parkinson disease.

Kamagata K, Hatano T, Okuzumi A, Motoi Y, Abe O, Shimoji K, Kamiya K, Suzuki M, Hori M, Kumamaru KK, Hattori N, Aoki S.

Eur Radiol. 2016 Aug;26(8):2567-77. doi: 10.1007/s00330-015-4066-8. Epub 2015 Oct 29.


Diffusion-tensor-based method for robust and practical estimation of axial and radial diffusional kurtosis.

Tachibana Y, Obata T, Tsuchiya H, Omatsu T, Kishimoto R, Kawaguchi H, Nishikori A, Kamagata K, Hori M, Aoki S, Tsuji H, Inoue T.

Eur Radiol. 2016 Aug;26(8):2559-66. doi: 10.1007/s00330-015-4038-z. Epub 2015 Oct 7.


One-Dimensional Sliding of p53 Along DNA Is Accelerated in the Presence of Ca(2+) or Mg(2+) at Millimolar Concentrations.

Murata A, Ito Y, Kashima R, Kanbayashi S, Nanatani K, Igarashi C, Okumura M, Inaba K, Tokino T, Takahashi S, Kamagata K.

J Mol Biol. 2015 Aug 14;427(16):2663-78. doi: 10.1016/j.jmb.2015.06.016. Epub 2015 Jul 2.


Bone marrow lesions, subchondral bone cysts and subchondral bone attrition are associated with histological synovitis in patients with end-stage knee osteoarthritis: a cross-sectional study.

Yusup A, Kaneko H, Liu L, Ning L, Sadatsuki R, Hada S, Kamagata K, Kinoshita M, Futami I, Shimura Y, Tsuchiya M, Saita Y, Takazawa Y, Ikeda H, Aoki S, Kaneko K, Ishijima M.

Osteoarthritis Cartilage. 2015 Nov;23(11):1858-64. doi: 10.1016/j.joca.2015.05.017. Epub 2015 May 29.


Complexity of the folding transition of the B domain of protein A revealed by the high-speed tracking of single-molecule fluorescence time series.

Oikawa H, Kamagata K, Arai M, Takahashi S.

J Phys Chem B. 2015 May 21;119(20):6081-91. doi: 10.1021/acs.jpcb.5b00414. Epub 2015 May 8.


See-through Brains and Diffusion Tensor MRI Clarified Fiber Connections: A Preliminary Microstructural Study in a Mouse with Callosal Agenesis.

Kerever A, Kamagata K, Yokosawa S, Otake Y, Ochi H, Yamada T, Hori M, Kamiya K, Nishikori A, Aoki S, Arikawa-Hirasawa E.

Magn Reson Med Sci. 2015;14(2):159-62. doi: 10.2463/mrms.2014-0142. Epub 2015 Mar 31.

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