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Items: 1 to 50 of 582

1.

Hyaluronic acid-bilirubin nanomedicine for targeted modulation of dysregulated intestinal barrier, microbiome and immune responses in colitis.

Lee Y, Sugihara K, Gillilland MG 3rd, Jon S, Kamada N, Moon JJ.

Nat Mater. 2019 Aug 19. doi: 10.1038/s41563-019-0462-9. [Epub ahead of print]

PMID:
31427744
2.

Development of renal failure in PargParp-1 null and Timm23 hypomorphic mice.

Chen L, Gunji A, Uemura A, Fujihara H, Nakamoto K, Onodera T, Sasaki Y, Imamichi S, Isumi M, Nozaki T, Kamada N, Jishage KI, Masutani M.

Biochem Pharmacol. 2019 Sep;167:116-124. doi: 10.1016/j.bcp.2019.07.003. Epub 2019 Jul 19.

PMID:
31326434
3.

Citrobacter rodentium Induces Tissue-Resident Memory CD4+ T Cells.

Bishu S, Hou G, El Zaatari M, Bishu SR, Popke D, Zhang M, Grasberger H, Zou W, Stidham RW, Higgins PDR, Spence JR, Kamada N, Kao JY.

Infect Immun. 2019 Jun 20;87(7). pii: e00295-19. doi: 10.1128/IAI.00295-19. Print 2019 Jul.

PMID:
31061145
4.

A specific gene-microbe interaction drives the development of Crohn's disease-like colitis in mice.

Caruso R, Mathes T, Martens EC, Kamada N, Nusrat A, Inohara N, Núñez G.

Sci Immunol. 2019 Apr 19;4(34). pii: eaaw4341. doi: 10.1126/sciimmunol.aaw4341.

PMID:
31004013
5.

Fecal microbiota transplantation prevents Candida albicans from colonizing the gastrointestinal tract.

Matsuo K, Haku A, Bi B, Takahashi H, Kamada N, Yaguchi T, Saijo S, Yoneyama M, Goto Y.

Microbiol Immunol. 2019 May;63(5):155-163. doi: 10.1111/1348-0421.12680. Epub 2019 May 15.

PMID:
30919462
6.

Flagellin-mediated activation of IL-33-ST2 signaling by a pathobiont promotes intestinal fibrosis.

Imai J, Kitamoto S, Sugihara K, Nagao-Kitamoto H, Hayashi A, Morhardt TL, Kuffa P, Higgins PDR, Barnich N, Kamada N.

Mucosal Immunol. 2019 May;12(3):632-643. doi: 10.1038/s41385-019-0138-4. Epub 2019 Feb 11.

7.

IL-10 produced by macrophages regulates epithelial integrity in the small intestine.

Morhardt TL, Hayashi A, Ochi T, Quirós M, Kitamoto S, Nagao-Kitamoto H, Kuffa P, Atarashi K, Honda K, Kao JY, Nusrat A, Kamada N.

Sci Rep. 2019 Feb 4;9(1):1223. doi: 10.1038/s41598-018-38125-x.

8.

CD4+ Tissue-resident Memory T Cells Expand and Are a Major Source of Mucosal Tumour Necrosis Factor α in Active Crohn's Disease.

Bishu S, El Zaatari M, Hayashi A, Hou G, Bowers N, Kinnucan J, Manoogian B, Muza-Moons M, Zhang M, Grasberger H, Bourque C, Zou W, Higgins PDR, Spence JR, Stidham RW, Kamada N, Kao JY.

J Crohns Colitis. 2019 Jul 25;13(7):905-915. doi: 10.1093/ecco-jcc/jjz010.

PMID:
30715262
9.

The Role of Dietary Nutrients in Inflammatory Bowel Disease.

Sugihara K, Morhardt TL, Kamada N.

Front Immunol. 2019 Jan 15;9:3183. doi: 10.3389/fimmu.2018.03183. eCollection 2018. Review.

10.

Gut pathobionts underlie intestinal barrier dysfunction and liver T helper 17 cell immune response in primary sclerosing cholangitis.

Nakamoto N, Sasaki N, Aoki R, Miyamoto K, Suda W, Teratani T, Suzuki T, Koda Y, Chu PS, Taniki N, Yamaguchi A, Kanamori M, Kamada N, Hattori M, Ashida H, Sakamoto M, Atarashi K, Narushima S, Yoshimura A, Honda K, Sato T, Kanai T.

Nat Microbiol. 2019 Mar;4(3):492-503. doi: 10.1038/s41564-018-0333-1. Epub 2019 Jan 14.

PMID:
30643240
11.

Raman-Enhanced Spectroscopy Distinguishes Anal Squamous Intraepithelial Lesions in Human Immunodeficiency Virus-Serodiscordant Couples.

Oda R, Agsalda-Garcia M, Loi N, Kamada N, Milne C, Killeen J, Choi SY, Lim E, Acosta-Maeda T, Misra A, Shiramizu B.

AIDS Res Hum Retroviruses. 2019 Mar;35(3):287-294. doi: 10.1089/AID.2018.0198. Epub 2019 Feb 4.

PMID:
30612435
12.

Microbiota-Derived Lactate Accelerates Intestinal Stem-Cell-Mediated Epithelial Development.

Lee YS, Kim TY, Kim Y, Lee SH, Kim S, Kang SW, Yang JY, Baek IJ, Sung YH, Park YY, Hwang SW, O E, Kim KS, Liu S, Kamada N, Gao N, Kweon MN.

Cell Host Microbe. 2018 Dec 12;24(6):833-846.e6. doi: 10.1016/j.chom.2018.11.002.

PMID:
30543778
13.

[The relationship between death from renal insufficiency and diuretic therapy among older adults at two nursing homes catering atomic bomb survivors].

Okada K, Yamaguchi Y, Kamada N, Abe K, Wagou M, Katoh S, Sasaki H, Okada M, Saheki N.

Nihon Ronen Igakkai Zasshi. 2018;55(4):640-649. doi: 10.3143/geriatrics.55.640. Japanese.

14.

The regenerating family member 3 β instigates IL-17A-mediated neutrophil recruitment downstream of NOD1/2 signalling for controlling colonisation resistance independently of microbiota community structure.

Waldschmitt N, Kitamoto S, Secher T, Zacharioudaki V, Boulard O, Floquet E, Delacre M, Lamas B, Pham HP, Six A, Richard ML, Dagorn JC, Eberl G, Langella P, Chatel JM, Ryffel B, Iovanna JL, Poulin LF, Sokol H, Kamada N, Chamaillard M.

Gut. 2019 Jul;68(7):1190-1199. doi: 10.1136/gutjnl-2018-316757. Epub 2018 Oct 2.

PMID:
30279238
15.

Unique Raman Spectroscopic Fingerprints of B-Cell Non-Hodgkin Lymphoma: Implications for Diagnosis, Prognosis and New Therapies.

Shiramizu B, Oda R, Kamada N, Garcia MA, Shieh T, Maeda TA, Choi SY, Lim E, Misra A.

J Biol Med Sci. 2018;2(1). pii: 105. Epub 2018 Jan 18.

16.

Regional control of regulatory immune cells in the intestine.

Morhardt TL, Hayashi A, Kao JY, Kamada N.

Curr Pathobiol Rep. 2018 Mar;6(1):29-34. Epub 2018 Jan 12.

17.

Bile acid metabolism regulated by the gut microbiota promotes non-alcoholic steatohepatitis-associated hepatocellular carcinoma in mice.

Yamada S, Takashina Y, Watanabe M, Nagamine R, Saito Y, Kamada N, Saito H.

Oncotarget. 2018 Jan 6;9(11):9925-9939. doi: 10.18632/oncotarget.24066. eCollection 2018 Feb 9.

18.

Expression and regulation of proton-coupled oligopeptide transporters in colonic tissue and immune cells of mice.

Wang Y, Hu Y, Li P, Weng Y, Kamada N, Jiang H, Smith DE.

Biochem Pharmacol. 2018 Feb;148:163-173. doi: 10.1016/j.bcp.2017.12.025. Epub 2018 Jan 3.

19.

Gut microbiota-mediated generation of saturated fatty acids elicits inflammation in the liver in murine high-fat diet-induced steatohepatitis.

Yamada S, Kamada N, Amiya T, Nakamoto N, Nakaoka T, Kimura M, Saito Y, Ejima C, Kanai T, Saito H.

BMC Gastroenterol. 2017 Nov 29;17(1):136. doi: 10.1186/s12876-017-0689-3.

20.

Commensal Lactobacillus Controls Immune Tolerance during Acute Liver Injury in Mice.

Nakamoto N, Amiya T, Aoki R, Taniki N, Koda Y, Miyamoto K, Teratani T, Suzuki T, Chiba S, Chu PS, Hayashi A, Yamaguchi A, Shiba S, Miyake R, Katayama T, Suda W, Mikami Y, Kamada N, Ebinuma H, Saito H, Hattori M, Kanai T.

Cell Rep. 2017 Oct 31;21(5):1215-1226. doi: 10.1016/j.celrep.2017.10.022.

21.

Quantitative proteomics identifies STEAP4 as a critical regulator of mitochondrial dysfunction linking inflammation and colon cancer.

Xue X, Bredell BX, Anderson ER, Martin A, Mays C, Nagao-Kitamoto H, Huang S, Győrffy B, Greenson JK, Hardiman K, Spence JR, Kamada N, Shah YM.

Proc Natl Acad Sci U S A. 2017 Nov 7;114(45):E9608-E9617. doi: 10.1073/pnas.1712946114. Epub 2017 Oct 23.

22.

Indoleamine 2,3-Dioxygenase 1, Increased in Human Gastric Pre-Neoplasia, Promotes Inflammation and Metaplasia in Mice and Is Associated With Type II Hypersensitivity/Autoimmunity.

El-Zaatari M, Bass AJ, Bowlby R, Zhang M, Syu LJ, Yang Y, Grasberger H, Shreiner A, Tan B, Bishu S, Leung WK, Todisco A, Kamada N, Cascalho M, Dlugosz AA, Kao JY.

Gastroenterology. 2018 Jan;154(1):140-153.e17. doi: 10.1053/j.gastro.2017.09.002. Epub 2017 Sep 11.

23.

Intestinal Dysbiosis and Biotin Deprivation Induce Alopecia through Overgrowth of Lactobacillus murinus in Mice.

Hayashi A, Mikami Y, Miyamoto K, Kamada N, Sato T, Mizuno S, Naganuma M, Teratani T, Aoki R, Fukuda S, Suda W, Hattori M, Amagai M, Ohyama M, Kanai T.

Cell Rep. 2017 Aug 15;20(7):1513-1524. doi: 10.1016/j.celrep.2017.07.057.

24.

Mesenchymal Cell-Specific MyD88 Signaling Promotes Systemic Dissemination of Salmonella Typhimurium via Inflammatory Monocytes.

Kim D, Seo SU, Zeng MY, Kim WU, Kamada N, Inohara N, Núñez G.

J Immunol. 2017 Aug 15;199(4):1362-1371. doi: 10.4049/jimmunol.1601527. Epub 2017 Jul 3.

25.

IL-22 Controls Iron-Dependent Nutritional Immunity Against Systemic Bacterial Infections.

Sakamoto K, Kim YG, Hara H, Kamada N, Caballero-Flores G, Tolosano E, Soares MP, Puente JL, Inohara N, Núñez G.

Sci Immunol. 2017 Feb;2(8). pii: eaai8371. doi: 10.1126/sciimmunol.aai8371. Epub 2017 Feb 3.

26.

Host-microbial Cross-talk in Inflammatory Bowel Disease.

Nagao-Kitamoto H, Kamada N.

Immune Netw. 2017 Feb;17(1):1-12. doi: 10.4110/in.2017.17.1.1. Epub 2017 Feb 23. Review.

27.

Development and validation of an LC-MS/MS method for simultaneously determining doxapram and keto-doxapram in human serum.

Suzuki Y, Kamada N, Ohno H, Abe Y, Endo T, Kobayashi M.

Bioanalysis. 2017 Mar;9(6):503-515. doi: 10.4155/bio-2016-0267. Epub 2017 Feb 22.

PMID:
28225296
28.

Synthesis and optimization of novel α-phenylglycinamides as selective TRPM8 antagonists.

Kobayashi JI, Hirasawa H, Ozawa T, Ozawa T, Takeda H, Fujimori Y, Nakanishi O, Kamada N, Ikeda T.

Bioorg Med Chem. 2017 Jan 15;25(2):727-742. doi: 10.1016/j.bmc.2016.11.049. Epub 2016 Nov 30.

PMID:
27964995
29.

The experience of dissolving polypharmacy by reducing the prescription of anti-ulcer drugs in residents of a special geriatric nursing home.

Okada K, Yamaguch Y, Kamada N, Okada M, Katoh S, Sasaki H.

Nihon Ronen Igakkai Zasshi. 2016;53(4):396-403. Japanese.

30.

A Dietary Fiber-Deprived Gut Microbiota Degrades the Colonic Mucus Barrier and Enhances Pathogen Susceptibility.

Desai MS, Seekatz AM, Koropatkin NM, Kamada N, Hickey CA, Wolter M, Pudlo NA, Kitamoto S, Terrapon N, Muller A, Young VB, Henrissat B, Wilmes P, Stappenbeck TS, Núñez G, Martens EC.

Cell. 2016 Nov 17;167(5):1339-1353.e21. doi: 10.1016/j.cell.2016.10.043.

31.

Functional Characterization of Inflammatory Bowel Disease-Associated Gut Dysbiosis in Gnotobiotic Mice.

Nagao-Kitamoto H, Shreiner AB, Gillilland MG 3rd, Kitamoto S, Ishii C, Hirayama A, Kuffa P, El-Zaatari M, Grasberger H, Seekatz AM, Higgins PD, Young VB, Fukuda S, Kao JY, Kamada N.

Cell Mol Gastroenterol Hepatol. 2016 Mar 3;2(4):468-481. eCollection 2016 Jul.

32.

Establishment of a new three-dimensional human epidermal model reconstructed from plucked hair follicle-derived keratinocytes.

Nakano M, Kamada N, Suehiro K, Oikawa A, Shibata C, Nakamura Y, Matsue H, Sasahara Y, Hosokawa H, Nakayama T, Nonaka K, Ohara O.

Exp Dermatol. 2016 Nov;25(11):903-906. doi: 10.1111/exd.13066. No abstract available.

PMID:
27194575
33.

Corrigendum: Nod2-mediated recognition of the microbiota is critical for mucosal adjuvant activity of cholera toxin.

Kim D, Kim YG, Seo SU, Kim DJ, Kamada N, Prescott D, Philpott DJ, Rosenstiel P, Inohara N, Núñez G.

Nat Med. 2016 Aug 4;22(8):961. doi: 10.1038/nm0816-961. No abstract available.

PMID:
27490437
34.

The Innate Immune System: A Trigger for Many Chronic Inflammatory Intestinal Diseases.

Kamada N, Rogler G.

Inflamm Intest Dis. 2016 Jul;1(2):70-77. doi: 10.1159/000445261. Epub 2016 Apr 28. Review.

35.

Diet-dependent, microbiota-independent regulation of IL-10-producing lamina propria macrophages in the small intestine.

Ochi T, Feng Y, Kitamoto S, Nagao-Kitamoto H, Kuffa P, Atarashi K, Honda K, Teitelbaum DH, Kamada N.

Sci Rep. 2016 Jun 15;6:27634. doi: 10.1038/srep27634.

36.

Pathogenic role of the gut microbiota in gastrointestinal diseases.

Nagao-Kitamoto H, Kitamoto S, Kuffa P, Kamada N.

Intest Res. 2016 Apr;14(2):127-38. doi: 10.5217/ir.2016.14.2.127. Epub 2016 Apr 27. Review.

37.

Nod2-mediated recognition of the microbiota is critical for mucosal adjuvant activity of cholera toxin.

Kim D, Kim YG, Seo SU, Kim DJ, Kamada N, Prescott D, Chamaillard M, Philpott DJ, Rosenstiel P, Inohara N, Núñez G.

Nat Med. 2016 May;22(5):524-30. doi: 10.1038/nm.4075. Epub 2016 Apr 11. Erratum in: Nat Med. 2016 Aug 4;22(8):961.

38.

Reduction of diuretics and analysis of water and muscle volumes to prevent falls and fall-related fractures in older adults.

Okada K, Okada M, Kamada N, Yamaguchi Y, Kakehashi M, Sasaki H, Katoh S, Morita K.

Geriatr Gerontol Int. 2017 Feb;17(2):262-269. doi: 10.1111/ggi.12719. Epub 2016 Feb 3.

PMID:
26840036
39.

Regulation of virulence: the rise and fall of gastrointestinal pathogens.

Kitamoto S, Nagao-Kitamoto H, Kuffa P, Kamada N.

J Gastroenterol. 2016 Mar;51(3):195-205. doi: 10.1007/s00535-015-1141-5. Epub 2015 Nov 10. Review.

40.

Th17 Cell Induction by Adhesion of Microbes to Intestinal Epithelial Cells.

Atarashi K, Tanoue T, Ando M, Kamada N, Nagano Y, Narushima S, Suda W, Imaoka A, Setoyama H, Nagamori T, Ishikawa E, Shima T, Hara T, Kado S, Jinnohara T, Ohno H, Kondo T, Toyooka K, Watanabe E, Yokoyama S, Tokoro S, Mori H, Noguchi Y, Morita H, Ivanov II, Sugiyama T, Nuñez G, Camp JG, Hattori M, Umesaki Y, Honda K.

Cell. 2015 Oct 8;163(2):367-80. doi: 10.1016/j.cell.2015.08.058. Epub 2015 Sep 24.

41.

Intestinal macrophages arising from CCR2(+) monocytes control pathogen infection by activating innate lymphoid cells.

Seo SU, Kuffa P, Kitamoto S, Nagao-Kitamoto H, Rousseau J, Kim YG, Núñez G, Kamada N.

Nat Commun. 2015 Aug 13;6:8010. doi: 10.1038/ncomms9010.

42.

Increased Expression of DUOX2 Is an Epithelial Response to Mucosal Dysbiosis Required for Immune Homeostasis in Mouse Intestine.

Grasberger H, Gao J, Nagao-Kitamoto H, Kitamoto S, Zhang M, Kamada N, Eaton KA, El-Zaatari M, Shreiner AB, Merchant JL, Owyang C, Kao JY.

Gastroenterology. 2015 Dec;149(7):1849-59. doi: 10.1053/j.gastro.2015.07.062. Epub 2015 Aug 7.

43.

Humoral Immunity in the Gut Selectively Targets Phenotypically Virulent Attaching-and-Effacing Bacteria for Intraluminal Elimination.

Kamada N, Sakamoto K, Seo SU, Zeng MY, Kim YG, Cascalho M, Vallance BA, Puente JL, Núñez G.

Cell Host Microbe. 2015 May 13;17(5):617-27. doi: 10.1016/j.chom.2015.04.001. Epub 2015 Apr 30.

44.

Distinct Commensals Induce Interleukin-1β via NLRP3 Inflammasome in Inflammatory Monocytes to Promote Intestinal Inflammation in Response to Injury.

Seo SU, Kamada N, Muñoz-Planillo R, Kim YG, Kim D, Koizumi Y, Hasegawa M, Himpsl SD, Browne HP, Lawley TD, Mobley HL, Inohara N, Núñez G.

Immunity. 2015 Apr 21;42(4):744-55. doi: 10.1016/j.immuni.2015.03.004. Epub 2015 Apr 7.

45.

Interleukin-22 regulates the complement system to promote resistance against pathobionts after pathogen-induced intestinal damage.

Hasegawa M, Yada S, Liu MZ, Kamada N, Muñoz-Planillo R, Do N, Núñez G, Inohara N.

Immunity. 2014 Oct 16;41(4):620-32. doi: 10.1016/j.immuni.2014.09.010.

46.

TACI deficiency enhances antibody avidity and clearance of an intestinal pathogen.

Tsuji S, Stein L, Kamada N, Nuñez G, Bram R, Vallance BA, Sousa AE, Platt JL, Cascalho M.

J Clin Invest. 2014 Nov;124(11):4857-66. doi: 10.1172/JCI74428. Epub 2014 Oct 1.

47.

Population pharmacokinetics of doxapram in low-birth-weight Japanese infants with apnea.

Ogawa Y, Irikura M, Kobaru Y, Tomiyasu M, Kochiyama Y, Uriu M, Ishitsuka Y, Kondo Y, Yukawa E, Kamada N, Ohno H, Yamazaki T, Irie T.

Eur J Pediatr. 2015 Apr;174(4):509-18. doi: 10.1007/s00431-014-2416-1. Epub 2014 Sep 25.

PMID:
25248340
48.

Cross-talk between RORγt+ innate lymphoid cells and intestinal macrophages induces mucosal IL-22 production in Crohn's disease.

Mizuno S, Mikami Y, Kamada N, Handa T, Hayashi A, Sato T, Matsuoka K, Matano M, Ohta Y, Sugita A, Koganei K, Sahara R, Takazoe M, Hisamatsu T, Kanai T.

Inflamm Bowel Dis. 2014 Aug;20(8):1426-34. doi: 10.1097/MIB.0000000000000105.

PMID:
24991784
49.

Tryptophan catabolism restricts IFN-γ-expressing neutrophils and Clostridium difficile immunopathology.

El-Zaatari M, Chang YM, Zhang M, Franz M, Shreiner A, McDermott AJ, van der Sluijs KF, Lutter R, Grasberger H, Kamada N, Young VB, Huffnagle GB, Kao JY.

J Immunol. 2014 Jul 15;193(2):807-16. doi: 10.4049/jimmunol.1302913. Epub 2014 Jun 16.

50.

Selection and characterization of promoters based on genomic approach for the molecular breeding of oleaginous fungus Mortierella alpina 1S-4.

Okuda T, Ando A, Sakuradani E, Kikukawa H, Kamada N, Ochiai M, Shima J, Ogawa J.

Curr Genet. 2014 Aug;60(3):183-91. doi: 10.1007/s00294-014-0423-4. Epub 2014 Feb 22.

PMID:
24562865

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