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Items: 12

1.

Targeting nucleotide exchange to inhibit constitutively active G protein α subunits in cancer cells.

Onken MD, Makepeace CM, Kaltenbronn KM, Kanai SM, Todd TD, Wang S, Broekelmann TJ, Rao PK, Cooper JA, Blumer KJ.

Sci Signal. 2018 Sep 4;11(546). pii: eaao6852. doi: 10.1126/scisignal.aao6852.

2.

Regulation of neurite morphogenesis by interaction between R7 regulator of G protein signaling complexes and G protein subunit Gα13.

Scherer SL, Cain MD, Kanai SM, Kaltenbronn KM, Blumer KJ.

J Biol Chem. 2017 Jun 16;292(24):9906-9918. doi: 10.1074/jbc.M116.771923. Epub 2017 Apr 21.

3.

GIRK channel modulation by assembly with allosterically regulated RGS proteins.

Zhou H, Chisari M, Raehal KM, Kaltenbronn KM, Bohn LM, Mennerick SJ, Blumer KJ.

Proc Natl Acad Sci U S A. 2012 Dec 4;109(49):19977-82. doi: 10.1073/pnas.1214337109. Epub 2012 Nov 19.

4.

Breast cancer cell targeting by prenylation inhibitors elucidated in living animals with a bioluminescence reporter.

Chinault SL, Prior JL, Kaltenbronn KM, Penly A, Weilbaecher KN, Piwnica-Worms D, Blumer KJ.

Clin Cancer Res. 2012 Aug 1;18(15):4136-44. doi: 10.1158/1078-0432.CCR-12-0642. Epub 2012 Jun 12.

5.

Regulator of G protein signaling 2 deficiency causes endothelial dysfunction and impaired endothelium-derived hyperpolarizing factor-mediated relaxation by dysregulating Gi/o signaling.

Osei-Owusu P, Sabharwal R, Kaltenbronn KM, Rhee MH, Chapleau MW, Dietrich HH, Blumer KJ.

J Biol Chem. 2012 Apr 6;287(15):12541-9. doi: 10.1074/jbc.M111.332130. Epub 2012 Feb 21.

6.

Genetic ablation of calcium-independent phospholipase A(2)beta causes hypercontractility and markedly attenuates endothelium-dependent relaxation to acetylcholine.

Dietrich HH, Abendschein DR, Moon SH, Nayeb-Hashemi N, Mancuso DJ, Jenkins CM, Kaltenbronn KM, Blumer KJ, Turk J, Gross RW.

Am J Physiol Heart Circ Physiol. 2010 Jun;298(6):H2208-20. doi: 10.1152/ajpheart.00839.2009. Epub 2010 Apr 9.

7.

Postnatal induction and localization of R7BP, a membrane-anchoring protein for regulator of G protein signaling 7 family-Gbeta5 complexes in brain.

Grabowska D, Jayaraman M, Kaltenbronn KM, Sandiford SL, Wang Q, Jenkins S, Slepak VZ, Smith Y, Blumer KJ.

Neuroscience. 2008 Feb 19;151(4):969-82. doi: 10.1016/j.neuroscience.2007.11.045. Epub 2007 Dec 8.

8.

R7BP augments the function of RGS7*Gbeta5 complexes by a plasma membrane-targeting mechanism.

Drenan RM, Doupnik CA, Jayaraman M, Buchwalter AL, Kaltenbronn KM, Huettner JE, Linder ME, Blumer KJ.

J Biol Chem. 2006 Sep 22;281(38):28222-31. Epub 2006 Jul 25.

9.

RGS2 is a mediator of nitric oxide action on blood pressure and vasoconstrictor signaling.

Sun X, Kaltenbronn KM, Steinberg TH, Blumer KJ.

Mol Pharmacol. 2005 Mar;67(3):631-9. Epub 2004 Nov 24.

PMID:
15563583
10.

Regulator of G-protein signaling-2 mediates vascular smooth muscle relaxation and blood pressure.

Tang KM, Wang GR, Lu P, Karas RH, Aronovitz M, Heximer SP, Kaltenbronn KM, Blumer KJ, Siderovski DP, Zhu Y, Mendelsohn ME.

Nat Med. 2003 Dec;9(12):1506-12. Epub 2003 Nov 9. Erratum in: Nat Med. 2004 Jan;10(1):105. Tang, Mary [corrected to Tang, K Mary]; Wang, Guang [corrected to Wang, Guang-rong].

PMID:
14608379
11.

Hypertension and prolonged vasoconstrictor signaling in RGS2-deficient mice.

Heximer SP, Knutsen RH, Sun X, Kaltenbronn KM, Rhee MH, Peng N, Oliveira-dos-Santos A, Penninger JM, Muslin AJ, Steinberg TH, Wyss JM, Mecham RP, Blumer KJ.

J Clin Invest. 2003 Apr;111(8):1259. No abstract available.

12.

Hypertension and prolonged vasoconstrictor signaling in RGS2-deficient mice.

Heximer SP, Knutsen RH, Sun X, Kaltenbronn KM, Rhee MH, Peng N, Oliveira-dos-Santos A, Penninger JM, Muslin AJ, Steinberg TH, Wyss JM, Mecham RP, Blumer KJ.

J Clin Invest. 2003 Feb;111(4):445-52.

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