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Items: 39


Cell-type specific polysome profiling from mammalian tissues.

Seimetz J, Arif W, Bangru S, Hernaez M, Kalsotra A.

Methods. 2019 Feb 15;155:131-139. doi: 10.1016/j.ymeth.2018.11.015. Epub 2018 Nov 27.


Alternative splicing rewires Hippo signaling pathway in hepatocytes to promote liver regeneration.

Bangru S, Arif W, Seimetz J, Bhate A, Chen J, Rashan EH, Carstens RP, Anakk S, Kalsotra A.

Nat Struct Mol Biol. 2018 Oct;25(10):928-939. doi: 10.1038/s41594-018-0129-2. Epub 2018 Sep 24.


Deregulation of RNA Metabolism in Microsatellite Expansion Diseases.

Misra C, Lin F, Kalsotra A.

Adv Neurobiol. 2018;20:213-238. doi: 10.1007/978-3-319-89689-2_8. Review.


Correction: Impaired Mitochondrial Energy Production Causes Light-Induced Photoreceptor Degeneration Independent of Oxidative Stress.

Jaiswal M, Haelterman NA, Sandoval H, Xiong B, Donti T, Kalsotra A, Yamamoto S, Cooper TA, Graham BH, Bellen HJ.

PLoS Biol. 2018 Mar 6;16(3):e1002622. doi: 10.1371/journal.pbio.1002622. eCollection 2018 Mar.


Mdm2 mediates FMRP- and Gp1 mGluR-dependent protein translation and neural network activity.

Liu DC, Seimetz J, Lee KY, Kalsotra A, Chung HJ, Lu H, Tsai NP.

Hum Mol Genet. 2017 Oct 15;26(20):3895-3908. doi: 10.1093/hmg/ddx276.


Maternal Dead-end 1 promotes translation of nanos1 by binding the eIF3 complex.

Aguero T, Jin Z, Chorghade S, Kalsotra A, King ML, Yang J.

Development. 2017 Oct 15;144(20):3755-3765. doi: 10.1242/dev.152611. Epub 2017 Sep 4.


Mov10 suppresses retroelements and regulates neuronal development and function in the developing brain.

Skariah G, Seimetz J, Norsworthy M, Lannom MC, Kenny PJ, Elrakhawy M, Forsthoefel C, Drnevich J, Kalsotra A, Ceman S.

BMC Biol. 2017 Jun 29;15(1):54. doi: 10.1186/s12915-017-0387-1.


Poly(A) tail length regulates PABPC1 expression to tune translation in the heart.

Chorghade S, Seimetz J, Emmons R, Yang J, Bresson SM, Lisio M, Parise G, Conrad NK, Kalsotra A.

Elife. 2017 Jun 27;6. pii: e24139. doi: 10.7554/eLife.24139.


Myotonic dystrophy: disease repeat range, penetrance, age of onset, and relationship between repeat size and phenotypes.

Yum K, Wang ET, Kalsotra A.

Curr Opin Genet Dev. 2017 Jun;44:30-37. doi: 10.1016/j.gde.2017.01.007. Epub 2017 Feb 14. Review.


RNA modifications and structures cooperate to guide RNA-protein interactions.

Lewis CJ, Pan T, Kalsotra A.

Nat Rev Mol Cell Biol. 2017 Mar;18(3):202-210. doi: 10.1038/nrm.2016.163. Epub 2017 Feb 1. Review.


Intersections of post-transcriptional gene regulatory mechanisms with intermediary metabolism.

Arif W, Datar G, Kalsotra A.

Biochim Biophys Acta Gene Regul Mech. 2017 Mar;1860(3):349-362. doi: 10.1016/j.bbagrm.2017.01.004. Epub 2017 Jan 11. Review.


Advances in analyzing RNA diversity in eukaryotic transcriptomes: peering through the Omics lens.

Bangru S, Kalsotra A.

F1000Res. 2016 Nov 14;5:2668. eCollection 2016. Review.


ESRP2 controls an adult splicing programme in hepatocytes to support postnatal liver maturation.

Bhate A, Parker DJ, Bebee TW, Ahn J, Arif W, Rashan EH, Chorghade S, Chau A, Lee JH, Anakk S, Carstens RP, Xiao X, Kalsotra A.

Nat Commun. 2015 Nov 4;6:8768. doi: 10.1038/ncomms9768.


Impaired Mitochondrial Energy Production Causes Light-Induced Photoreceptor Degeneration Independent of Oxidative Stress.

Jaiswal M, Haelterman NA, Sandoval H, Xiong B, Donti T, Kalsotra A, Yamamoto S, Cooper TA, Graham BH, Bellen HJ.

PLoS Biol. 2015 Jul 15;13(7):e1002197. doi: 10.1371/journal.pbio.1002197. eCollection 2015 Jul. Erratum in: PLoS Biol. 2018 Mar 6;16(3):e1002622.


Systematic profiling of poly(A)+ transcripts modulated by core 3' end processing and splicing factors reveals regulatory rules of alternative cleavage and polyadenylation.

Li W, You B, Hoque M, Zheng D, Luo W, Ji Z, Park JY, Gunderson SI, Kalsotra A, Manley JL, Tian B.

PLoS Genet. 2015 Apr 23;11(4):e1005166. doi: 10.1371/journal.pgen.1005166. eCollection 2015 Apr.


Uncovering RNA binding proteins associated with age and gender during liver maturation.

Chaturvedi P, Neelamraju Y, Arif W, Kalsotra A, Janga SC.

Sci Rep. 2015 Mar 31;5:9512. doi: 10.1038/srep09512.


Developmental insights into the pathology of and therapeutic strategies for DM1: Back to the basics.

Chau A, Kalsotra A.

Dev Dyn. 2015 Mar;244(3):377-90. doi: 10.1002/dvdy.24240. Epub 2015 Jan 13. Review.


Rbfox2-coordinated alternative splicing of Mef2d and Rock2 controls myoblast fusion during myogenesis.

Singh RK, Xia Z, Bland CS, Kalsotra A, Scavuzzo MA, Curk T, Ule J, Li W, Cooper TA.

Mol Cell. 2014 Aug 21;55(4):592-603. doi: 10.1016/j.molcel.2014.06.035. Epub 2014 Jul 31.


Alternative splicing regulates vesicular trafficking genes in cardiomyocytes during postnatal heart development.

Giudice J, Xia Z, Wang ET, Scavuzzo MA, Ward AJ, Kalsotra A, Wang W, Wehrens XH, Burge CB, Li W, Cooper TA.

Nat Commun. 2014 Apr 22;5:3603. doi: 10.1038/ncomms4603.


The Mef2 transcription network is disrupted in myotonic dystrophy heart tissue, dramatically altering miRNA and mRNA expression.

Kalsotra A, Singh RK, Gurha P, Ward AJ, Creighton CJ, Cooper TA.

Cell Rep. 2014 Jan 30;6(2):336-45. doi: 10.1016/j.celrep.2013.12.025. Epub 2014 Jan 9.


Functional consequences of developmentally regulated alternative splicing.

Kalsotra A, Cooper TA.

Nat Rev Genet. 2011 Sep 16;12(10):715-29. doi: 10.1038/nrg3052. Review.


MicroRNAs coordinate an alternative splicing network during mouse postnatal heart development.

Kalsotra A, Wang K, Li PF, Cooper TA.

Genes Dev. 2010 Apr 1;24(7):653-8. doi: 10.1101/gad.1894310. Epub 2010 Mar 18.


A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart.

Kalsotra A, Xiao X, Ward AJ, Castle JC, Johnson JM, Burge CB, Cooper TA.

Proc Natl Acad Sci U S A. 2008 Dec 23;105(51):20333-8. doi: 10.1073/pnas.0809045105. Epub 2008 Dec 15.


Expression of 24,426 human alternative splicing events and predicted cis regulation in 48 tissues and cell lines.

Castle JC, Zhang C, Shah JK, Kulkarni AV, Kalsotra A, Cooper TA, Johnson JM.

Nat Genet. 2008 Dec;40(12):1416-25. doi: 10.1038/ng.264. Epub 2008 Nov 2.


CYP4Fs expression in rat brain correlates with changes in LTB4 levels after traumatic brain injury.

Wang Y, Zhao J, Kalsotra A, Turman CM, Grill RJ, Dash PK, Strobel HW.

J Neurotrauma. 2008 Oct;25(10):1187-94. doi: 10.1089/neu.2008.0542.


Inflammation resolved by retinoid X receptor-mediated inactivation of leukotriene signaling pathways.

Kalsotra A, Du L, Wang Y, Ladd PA, Kikuta Y, Duvic M, Boyd AS, Keeney DS, Strobel HW.

FASEB J. 2008 Feb;22(2):538-47. Epub 2007 Sep 20.


Catalytic characterization and cytokine mediated regulation of cytochrome P450 4Fs in rat hepatocytes.

Kalsotra A, Anakk S, Brommer CL, Kikuta Y, Morgan ET, Strobel HW.

Arch Biochem Biophys. 2007 May 1;461(1):104-12. Epub 2007 Mar 15.


Brain trauma leads to enhanced lung inflammation and injury: evidence for role of P4504Fs in resolution.

Kalsotra A, Zhao J, Anakk S, Dash PK, Strobel HW.

J Cereb Blood Flow Metab. 2007 May;27(5):963-74. Epub 2006 Sep 20.


Cytochrome P450 4F subfamily: at the crossroads of eicosanoid and drug metabolism.

Kalsotra A, Strobel HW.

Pharmacol Ther. 2006 Dec;112(3):589-611. Epub 2006 Aug 22. Review.


Preparative high-performance liquid chromatographic separation of naphthodianthrones from St. John's Wort.

Puri S, Handa G, Kalsotra AK, Gupta VK, Shawl AS, Suri OP, Qazi GN.

J Chromatogr Sci. 2006 Apr;44(4):177-80.


Renal localization, expression, and developmental regulation of P450 4F cytochromes in three substrains of spontaneously hypertensive rats.

Kalsotra A, Cui X, Anakk S, Hinojos CA, Doris PA, Strobel HW.

Biochem Biophys Res Commun. 2005 Dec 9;338(1):423-31. Epub 2005 Aug 25.


Expression and characterization of human cytochrome P450 4F11: Putative role in the metabolism of therapeutic drugs and eicosanoids.

Kalsotra A, Turman CM, Kikuta Y, Strobel HW.

Toxicol Appl Pharmacol. 2004 Sep 15;199(3):295-304.


CAR/PXR provide directives for Cyp3a41 gene regulation differently from Cyp3a11.

Anakk S, Kalsotra A, Kikuta Y, Huang W, Zhang J, Staudinger JL, Moore DD, Strobel HW.

Pharmacogenomics J. 2004;4(2):91-101.


Differential effects of traumatic brain injury on the cytochrome p450 system: a perspective into hepatic and renal drug metabolism.

Kalsotra A, Turman CM, Dash PK, Strobel HW.

J Neurotrauma. 2003 Dec;20(12):1339-50.


Inflammatory prompts produce isoform-specific changes in the expression of leukotriene B(4) omega-hydroxylases in rat liver and kidney.

Kalsotra A, Cui X, Antonovic L, Robida AM, Morgan ET, Strobel HW.

FEBS Lett. 2003 Dec 4;555(2):236-42.


Genomic characterization and regulation of CYP3a13: role of xenobiotics and nuclear receptors.

Anakk S, Kalsotra A, Shen Q, Vu MT, Staudinger JL, Davies PJ, Strobel HW.

FASEB J. 2003 Sep;17(12):1736-8. Epub 2003 Jul 3.


Expression of cytochromes P450 4F4 and 4F5 in infection and injury models of inflammation.

Cui X, Kalsotra A, Robida AM, Matzilevich D, Moore AN, Boehme CL, Morgan ET, Dash PK, Strobel HW.

Biochim Biophys Acta. 2003 Feb 17;1619(3):325-31.


Sexual dimorphism and tissue specificity in the expression of CYP4F forms in Sprague Dawley rats.

Kalsotra A, Anakk S, Boehme CL, Strobel HW.

Drug Metab Dispos. 2002 Sep;30(9):1022-8.


Behavioural and anti-psychotic effects of Ca2+ channel blockers in rhesus monkey.

Palit G, Kalsotra A, Kumar R, Nath C, Dubey MP.

Eur J Pharmacol. 2001 Jan 26;412(2):139-44.


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