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Items: 30

1.

Significantly altered peripheral blood cell DNA methylation profile as a result of immediate effect of metformin use in healthy individuals.

Elbere I, Silamikelis I, Ustinova M, Kalnina I, Zaharenko L, Peculis R, Konrade I, Ciuculete DM, Zhukovsky C, Gudra D, Radovica-Spalvina I, Fridmanis D, Pirags V, Schiöth HB, Klovins J.

Clin Epigenetics. 2018 Dec 13;10(1):156. doi: 10.1186/s13148-018-0593-x.

2.

Association of metformin administration with gut microbiome dysbiosis in healthy volunteers.

Elbere I, Kalnina I, Silamikelis I, Konrade I, Zaharenko L, Sekace K, Radovica-Spalvina I, Fridmanis D, Gudra D, Pirags V, Klovins J.

PLoS One. 2018 Sep 27;13(9):e0204317. doi: 10.1371/journal.pone.0204317. eCollection 2018.

3.

A widely used sampling device in colorectal cancer screening programmes allows for large-scale microbiome studies.

Gudra D, Shoaie S, Fridmanis D, Klovins J, Wefer H, Silamikelis I, Peculis R, Kalnina I, Elbere I, Radovica-Spalvina I, Hultcrantz R, Šķenders Ģ, Leja M, Engstrand L.

Gut. 2019 Sep;68(9):1723-1725. doi: 10.1136/gutjnl-2018-316225. Epub 2018 Sep 21. No abstract available.

4.

Single nucleotide polymorphisms in the intergenic region between metformin transporter OCT2 and OCT3 coding genes are associated with short-term response to metformin monotherapy in type 2 diabetes mellitus patients.

Zaharenko L, Kalnina I, Geldnere K, Konrade I, Grinberga S, Židzik J, Javorský M, Lejnieks A, Nikitina-Zake L, Fridmanis D, Peculis R, Radovica-Spalvina I, Hartmane D, Pugovics O, Tkáč I, Klimčáková L, Pīrāgs V, Klovins J.

Eur J Endocrinol. 2016 Dec;175(6):531-540. Epub 2016 Sep 8.

PMID:
27609360
5.

Genome-wide analysis reveals DNA methylation markers that vary with both age and obesity.

Almén MS, Nilsson EK, Jacobsson JA, Kalnina I, Klovins J, Fredriksson R, Schiöth HB.

Gene. 2014 Sep 10;548(1):61-7. doi: 10.1016/j.gene.2014.07.009. Epub 2014 Jul 8.

6.

Location of novel benzanthrone dyes in model membranes as revealed by resonance energy transfer.

Zhytniakivska O, Trusova V, Gorbenko G, Kirilova E, Kalnina I, Kirilov G, Molotkovsky J, Tulkki J, Kinnunen P.

J Fluoresc. 2014 May;24(3):899-907. doi: 10.1007/s10895-014-1370-7. Epub 2014 Mar 5.

PMID:
24596055
7.

The role of common and rare MC4R variants and FTO polymorphisms in extreme form of obesity.

Rovite V, Petrovska R, Vaivade I, Kalnina I, Fridmanis D, Zaharenko L, Peculis R, Pirags V, Schioth HB, Klovins J.

Mol Biol Rep. 2014 Mar;41(3):1491-500. doi: 10.1007/s11033-013-2994-4. Epub 2014 Jan 3.

PMID:
24385306
8.

Fluorescence Investigation of Interactions Between Novel Benzanthrone Dyes and Lysozyme Amyloid Fibrils.

Vus K, Trusova V, Gorbenko G, Sood R, Kirilova E, Kirilov G, Kalnina I, Kinnunen P.

J Fluoresc. 2014 Mar;24(2):493-504. doi: 10.1007/s10895-013-1318-3. Epub 2013 Dec 27.

PMID:
24371000
9.

Polymorphisms in FTO and near TMEM18 associate with type 2 diabetes and predispose to younger age at diagnosis of diabetes.

Kalnina I, Zaharenko L, Vaivade I, Rovite V, Nikitina-Zake L, Peculis R, Fridmanis D, Geldnere K, Jacobsson JA, Almen MS, Pirags V, Schiöth HB, Klovins J.

Gene. 2013 Sep 25;527(2):462-8. doi: 10.1016/j.gene.2013.06.079. Epub 2013 Jul 13.

PMID:
23860325
10.

Association of genetic variation in the organic cation transporters OCT1, OCT2 and multidrug and toxin extrusion 1 transporter protein genes with the gastrointestinal side effects and lower BMI in metformin-treated type 2 diabetes patients.

Tarasova L, Kalnina I, Geldnere K, Bumbure A, Ritenberga R, Nikitina-Zake L, Fridmanis D, Vaivade I, Pirags V, Klovins J.

Pharmacogenet Genomics. 2012 Sep;22(9):659-66. doi: 10.1097/FPC.0b013e3283561666.

PMID:
22735389
11.

Determination of the obesity-associated gene variants within the entire FTO gene by ultra-deep targeted sequencing in obese and lean children.

Sällman Almén M, Rask-Andersen M, Jacobsson JA, Ameur A, Kalnina I, Moschonis G, Juhlin S, Bringeland N, Hedberg LA, Ignatovica V, Chrousos GP, Manios Y, Klovins J, Marcus C, Gyllensten U, Fredriksson R, Schiöth HB.

Int J Obes (Lond). 2013 Mar;37(3):424-31. doi: 10.1038/ijo.2012.57. Epub 2012 Apr 24.

12.

Stronger association of common variants in TCF7L2 gene with nonobese type 2 diabetes in the Latvian population.

Kalnina I, Geldnere K, Tarasova L, Nikitina-Zake L, Peculis R, Fridmanis D, Pirags V, Klovins J.

Exp Clin Endocrinol Diabetes. 2012 Sep;120(8):466-8. doi: 10.1055/s-0032-1306298. Epub 2012 Mar 22.

PMID:
22441719
13.

Novel benzanthrone aminoderivatives for membrane studies.

Trusova VM, Kirilova E, Kalnina I, Kirilov G, Zhytniakivska OA, Fedorov PV, Gorbenko GP.

J Fluoresc. 2012 May;22(3):953-9. doi: 10.1007/s10895-011-1035-8. Epub 2012 Jan 6.

PMID:
22218973
14.

Correlation of altered blood albumin characteristics and lymphocyte populations to tumor stage in gastrointestinal cancer patients.

Kalnina I, Kurjane N, Kirilova E, Klimkane L, Kirilov G, Zvagule T.

Cancer Biomark. 2010;7(2):91-9. doi: 10.3233/CBM-2010-0151.

PMID:
21178267
15.

Identification of domains responsible for specific membrane transport and ligand specificity of the ACTH receptor (MC2R).

Fridmanis D, Petrovska R, Kalnina I, Slaidina M, Peculis R, Schiöth HB, Klovins J.

Mol Cell Endocrinol. 2010 Jun 10;321(2):175-83. doi: 10.1016/j.mce.2010.02.032. Epub 2010 Mar 3.

PMID:
20206229
16.

Fluorescent study of human blood plasma albumin alterations induced by ionizing radiation.

Kirilova EM, Kalnina I, Zvagule T, Gabruseva N, Kurjane N, Solomenikova II.

J Fluoresc. 2011 May;21(3):923-7. doi: 10.1007/s10895-010-0608-2. Epub 2010 Feb 24.

PMID:
20179999
17.

Altered plasma albumin characteristics and lymphocyte populations in gastrointestinal cancer patients: detection using modified fluorescence responses.

Kalnina I, Kirilova E, Klimkane L, Kirilov G.

J Immunotoxicol. 2009 Dec;6(4):293-300. doi: 10.3109/15476910903280090.

PMID:
19845452
18.

Fluorescent probe ABM and estimation of immune state in patients with different pathologies (review article).

Kalnina I, Bruvere R, Zvagule T, Gabruseva N, Klimkane L, Kirilova E, Meirovics I, Kizane G.

J Fluoresc. 2010 Jan;20(1):9-17. doi: 10.1007/s10895-009-0515-6. Epub 2009 Aug 1. Review.

PMID:
19649695
19.

Association between a rare SNP in the second intron of human Agouti related protein gene and increased BMI.

Kalnina I, Kapa I, Pirags V, Ignatovica V, Schiöth HB, Klovins J.

BMC Med Genet. 2009 Jul 14;10:63. doi: 10.1186/1471-2350-10-63.

20.

3-Isopropyloxy-6-morpholino-2-phenylphenalen-1-one as lipophilic fluorescent probe for lymphocyte investigations.

Kirilova EM, Kalnina I.

Appl Biochem Biotechnol. 2010 Mar;160(6):1744-51. doi: 10.1007/s12010-009-8663-3. Epub 2009 May 14.

PMID:
19440662
21.

Spectroscopic study of benzanthrone 3-N-derivatives as new hydrophobic fluorescent probes for biomolecules.

Kirilova EM, Kalnina I, Kirilov GK, Meirovics I.

J Fluoresc. 2008 May-Jul;18(3-4):645-8. doi: 10.1007/s10895-008-0340-3. Epub 2008 May 22.

PMID:
18496742
22.

Fluorescent probe ABM for screening gastrointestinal patient's immune state.

Kalnina I, Klimkane L, Kirilova E, Toma MM, Kizane G, Meirovics I.

J Fluoresc. 2007 Nov;17(6):619-25. Epub 2007 Oct 10.

PMID:
17926122
23.

Structural changes in lymphocytes membrane of Chernobyl clean-up workers from Latvia.

Kalnina I, Zvagule T, Gabruseva N, Kirilova J, Kurjane N, Bruvere R, Kesters A, Kizane G, Kirilovs G, Meirovics I.

J Fluoresc. 2007 Nov;17(6):633-8. Epub 2007 Oct 9.

PMID:
17924176
24.

The evolutionary history and tissue mapping of GPR123: specific CNS expression pattern predominantly in thalamic nuclei and regions containing large pyramidal cells.

Lagerström MC, Rabe N, Haitina T, Kalnina I, Hellström AR, Klovins J, Kullander K, Schiöth HB.

J Neurochem. 2007 Feb;100(4):1129-42. Epub 2006 Dec 22.

25.

Fluorescent characteristics of rheumatoid arthritis patients blood lymphocytes.

Kalniņa I, Zvagule T, Brūvere R, Meirovics I.

J Fluoresc. 2005 Mar;15(2):105-10.

PMID:
15883763
26.
27.

Modification of the activity of mitochondrial monoamine oxidases in vitro and in vivo.

Baumanis EA, Kalnina IE, Kaminka ME, Mashkovsky MD, Gorkin VZ.

Agents Actions. 1981 Dec;11(6-7):685-92.

PMID:
7340462
28.

[Effect of temperature and composition of frozen solutions on the rate of peroxidase oxidation of 2,3-dimethyl-1,4-naphthoquinol-1-dimethylphosphate].

Sergeev GB, Sergeev BM, Kalnina IA, Nekrasova GN, Batiuk VA.

Biokhimiia. 1981 Nov;46(11):2089-91. Russian.

PMID:
7317533
29.

Modification of brain mitochondrial monoamine oxidase activities by hydroxyethylhydrazide of cyanoacetic acid and some other monoamine oxidase inhibitors.

Baumanis EA, Kalnina IE, Moskvitina TA, Gorkin VZ.

Biochem Pharmacol. 1977 Jun 1;26(11):1059-63. No abstract available.

PMID:
18152
30.

[Comparative study of the effect of inhibitors of monoamine oxidase and ftorafur on the growth of de-differentiated astrocytoma].

Baumanis EA, Kalnina IE, Brusovanik VI, Iablonovskaia LIa.

Arkh Patol. 1976;38(6):45-51. Russian.

PMID:
798569

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