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Items: 35

1.

Next-Generation Compound Delivery Platforms to Support Miniaturized Biology.

Bhatt S, Crimmin S, Gross J, Nixon E, Truong M, Weglos M, Kallal L.

SLAS Technol. 2019 Jun;24(3):245-255. doi: 10.1177/2472630318820017. Epub 2019 Feb 6.

PMID:
30726680
2.

A High-Throughput Dose-Response Cellular Thermal Shift Assay for Rapid Screening of Drug Target Engagement in Living Cells, Exemplified Using SMYD3 and IDO1.

McNulty DE, Bonnette WG, Qi H, Wang L, Ho TF, Waszkiewicz A, Kallal LA, Nagarajan RP, Stern M, Quinn AM, Creasy CL, Su DS, Graves AP, Annan RS, Sweitzer SM, Holbert MA.

SLAS Discov. 2018 Jan;23(1):34-46. doi: 10.1177/2472555217732014. Epub 2017 Sep 28.

PMID:
28957646
3.

A High-Content Imaging Screen for Cellular Regulators of β-Catenin Protein Abundance.

Zeng X, Montoute M, Bee TW, Lin H, Kallal LA, Liu Y, Agarwal P, Wang D, Lu Q, Morrow D, Pope AJ, Wu Z.

J Biomol Screen. 2016 Mar;21(3):260-8. doi: 10.1177/1087057115620169. Epub 2015 Dec 9.

PMID:
26656867
4.

TRIM68 negatively regulates IFN-β production by degrading TRK fused gene, a novel driver of IFN-β downstream of anti-viral detection systems.

Wynne C, Lazzari E, Smith S, McCarthy EM, Ní Gabhann J, Kallal LE, Higgs R, Greco A, Cryan SA, Biron CA, Jefferies CA.

PLoS One. 2014 Jul 7;9(7):e101503. doi: 10.1371/journal.pone.0101503. eCollection 2014. Erratum in: PLoS One. 2015;10(2):e0117957. Greco, Angela [added].

5.

Identification of selective small molecule inhibitors of the nucleotide-binding oligomerization domain 1 (NOD1) signaling pathway.

Rickard DJ, Sehon CA, Kasparcova V, Kallal LA, Haile PA, Zeng X, Montoute MN, Poore DD, Li H, Wu Z, Eidam PM, Emery JG, Marquis RW, Gough PJ, Bertin J.

PLoS One. 2014 May 7;9(5):e96737. doi: 10.1371/journal.pone.0096737. eCollection 2014.

6.

A novel approach applying a chemical biology strategy in phenotypic screening reveals pathway-selective regulators of histone 3 K27 tri-methylation.

Liu Y, Platchek M, Kement B, Bee WT, Truong M, Zeng X, Hung S, Lin H, Morrow D, Kallal LA, Xie Q, Agarwal P, Pope AJ, Wu Z.

Mol Biosyst. 2014 Feb;10(2):251-7. doi: 10.1039/c3mb70413k.

PMID:
24257700
7.

Development of phenotypic screening assays for γ-globin induction using primary human bone marrow day 7 erythroid progenitor cells.

Li H, Xie W, Gore ER, Montoute MN, Bee WT, Zappacosta F, Zeng X, Wu Z, Kallal L, Ames RS, Pope AJ, Benowitz A, Erickson-Miller CL.

J Biomol Screen. 2013 Dec;18(10):1212-22. doi: 10.1177/1087057113499776. Epub 2013 Oct 25.

PMID:
24163393
8.
9.

Identification of benzimidazole diamides as selective inhibitors of the nucleotide-binding oligomerization domain 2 (NOD2) signaling pathway.

Rickard DJ, Sehon CA, Kasparcova V, Kallal LA, Zeng X, Montoute MN, Chordia T, Poore DD, Li H, Wu Z, Eidam PM, Haile PA, Yu J, Emery JG, Marquis RW, Gough PJ, Bertin J.

PLoS One. 2013 Aug 1;8(8):e69619. doi: 10.1371/journal.pone.0069619. Print 2013.

10.

Respiratory syncytial virus infection modifies and accelerates pulmonary disease via DC activation and migration.

Jang S, Smit J, Kallal LE, Lukacs NW.

J Leukoc Biol. 2013 Jul;94(1):5-15. doi: 10.1189/jlb.0412195. Epub 2013 Jan 4.

11.

An orally active TRPV4 channel blocker prevents and resolves pulmonary edema induced by heart failure.

Thorneloe KS, Cheung M, Bao W, Alsaid H, Lenhard S, Jian MY, Costell M, Maniscalco-Hauk K, Krawiec JA, Olzinski A, Gordon E, Lozinskaya I, Elefante L, Qin P, Matasic DS, James C, Tunstead J, Donovan B, Kallal L, Waszkiewicz A, Vaidya K, Davenport EA, Larkin J, Burgert M, Casillas LN, Marquis RW, Ye G, Eidam HS, Goodman KB, Toomey JR, Roethke TJ, Jucker BM, Schnackenberg CG, Townsley MI, Lepore JJ, Willette RN.

Sci Transl Med. 2012 Nov 7;4(159):159ra148. doi: 10.1126/scitranslmed.3004276.

12.

The development of a high-content screening binding assay for the smoothened receptor.

Bee WT, Xie W, Truong M, Will M, Turunen B, Zuercher WJ, McMillan L, Li H, Hornberger KR, Davenport EA, Ames RS, Kallal LA.

J Biomol Screen. 2012 Aug;17(7):900-11. doi: 10.1177/1087057112447872. Epub 2012 May 29.

PMID:
22644265
13.

Type 1 interferon induction of natural killer cell gamma interferon production for defense during lymphocytic choriomeningitis virus infection.

Mack EA, Kallal LE, Demers DA, Biron CA.

MBio. 2011 Aug 9;2(4). pii: e00169-11. doi: 10.1128/mBio.00169-11. Print 2011.

14.

A novel inactivated intranasal respiratory syncytial virus vaccine promotes viral clearance without Th2 associated vaccine-enhanced disease.

Lindell DM, Morris SB, White MP, Kallal LE, Lundy PK, Hamouda T, Baker JR Jr, Lukacs NW.

PLoS One. 2011;6(7):e21823. doi: 10.1371/journal.pone.0021823. Epub 2011 Jul 15.

15.

Inefficient lymph node sensitization during respiratory viral infection promotes IL-17-mediated lung pathology.

Kallal LE, Hartigan AJ, Hogaboam CM, Schaller MA, Lukacs NW.

J Immunol. 2010 Oct 1;185(7):4137-47. doi: 10.4049/jimmunol.1000677. Epub 2010 Aug 30.

16.

CCR7 impairs hematopoiesis after hematopoietic stem cell transplantation increasing susceptibility to invasive aspergillosis.

Hartigan AJ, Kallal LE, Hogaboam CM.

Blood. 2010 Dec 9;116(24):5383-93. doi: 10.1182/blood-2010-01-265454. Epub 2010 Aug 9.

17.

Benzofuran-substituted urea derivatives as novel P2Y(1) receptor antagonists.

Thalji RK, Aiyar N, Davenport EA, Erhardt JA, Kallal LA, Morrow DM, Senadhi S, Burns-Kurtis CL, Marino JP Jr.

Bioorg Med Chem Lett. 2010 Jul 15;20(14):4104-7. doi: 10.1016/j.bmcl.2010.05.072. Epub 2010 Jun 9.

PMID:
20542694
18.

Development of a high-throughput cell-based assay for superoxide production in HL-60 cells.

Seitz PM, Cooper R, Gatto GJ Jr, Ramon F, Sweitzer TD, Johns DG, Davenport EA, Ames RS, Kallal LA.

J Biomol Screen. 2010 Apr;15(4):388-97. doi: 10.1177/1087057109359687. Epub 2010 Mar 12.

PMID:
20228280
19.

CCL20/CCR6 blockade enhances immunity to RSV by impairing recruitment of DC.

Kallal LE, Schaller MA, Lindell DM, Lira SA, Lukacs NW.

Eur J Immunol. 2010 Apr;40(4):1042-52. doi: 10.1002/eji.200939778.

20.

Evidence for allosteric interactions of antagonist binding to the smoothened receptor.

Rominger CM, Bee WL, Copeland RA, Davenport EA, Gilmartin A, Gontarek R, Hornberger KR, Kallal LA, Lai Z, Lawrie K, Lu Q, McMillan L, Truong M, Tummino PJ, Turunen B, Will M, Zuercher WJ, Rominger DH.

J Pharmacol Exp Ther. 2009 Jun;329(3):995-1005. doi: 10.1124/jpet.109.152090. Epub 2009 Mar 20. Erratum in: J Pharmacol Exp Ther. 2010 Feb;332(2):690.

PMID:
19304771
21.

M3 muscarinic acetylcholine receptor antagonists: SAR and optimization of bi-aryl amines.

Budzik B, Wang Y, Shi D, Wang F, Xie H, Wan Z, Zhu C, Foley JJ, Nuthulaganti P, Kallal LA, Sarau HM, Morrow DM, Moore ML, Rivero RA, Palovich M, Salmon M, Belmonte KE, Laine DI, Jin J.

Bioorg Med Chem Lett. 2009 Mar 15;19(6):1686-90. doi: 10.1016/j.bmcl.2009.01.098. Epub 2009 Feb 4.

PMID:
19243945
22.

Tetrahydro-4-quinolinamines identified as novel P2Y(1) receptor antagonists.

Morales-Ramos AI, Mecom JS, Kiesow TJ, Graybill TL, Brown GD, Aiyar NV, Davenport EA, Kallal LA, Knapp-Reed BA, Li P, Londregan AT, Morrow DM, Senadhi S, Thalji RK, Zhao S, Burns-Kurtis CL, Marino JP Jr.

Bioorg Med Chem Lett. 2008 Dec 1;18(23):6222-6. doi: 10.1016/j.bmcl.2008.09.102. Epub 2008 Oct 2.

PMID:
18926700
23.

The role of chemokines in virus-associated asthma exacerbations.

Kallal LE, Lukacs NW.

Curr Allergy Asthma Rep. 2008 Sep;8(5):443-50. Review.

PMID:
18682112
24.

Discovery of novel and long acting muscarinic acetylcholine receptor antagonists.

Jin J, Wang Y, Shi D, Wang F, Davis RS, Jin Q, Fu W, Foley JJ, Webb EF, Dehaas CJ, Berlanga M, Burman M, Sarau HM, Morrow DM, Rao P, Kallal LA, Moore ML, Rivero RA, Palovich M, Salmon M, Belmonte KE, Busch-Petersen J.

J Med Chem. 2008 Aug 28;51(16):4866-9. doi: 10.1021/jm800634k. Epub 2008 Aug 5.

PMID:
18680280
25.

A key role for CC chemokine receptor 1 in T-cell-mediated respiratory inflammation.

Schaller MA, Kallal LE, Lukacs NW.

Am J Pathol. 2008 Feb;172(2):386-94. doi: 10.2353/ajpath.2008.070537. Epub 2008 Jan 17.

26.

Notch ligand Delta-like 4 regulates disease pathogenesis during respiratory viral infections by modulating Th2 cytokines.

Schaller MA, Neupane R, Rudd BD, Kunkel SL, Kallal LE, Lincoln P, Lowe JB, Man Y, Lukacs NW.

J Exp Med. 2007 Nov 26;204(12):2925-34. Epub 2007 Nov 6.

27.
28.

Fluorescence microscopy techniques for the study of G protein-coupled receptor trafficking.

Kallal L, Benovic JL.

Methods Enzymol. 2002;343:492-506. No abstract available.

PMID:
11665588
29.

Using green fluorescent proteins to study G-protein-coupled receptor localization and trafficking.

Kallal L, Benovic JL.

Trends Pharmacol Sci. 2000 May;21(5):175-80. Review.

PMID:
10785651
30.
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35.

Functional analysis of the sporulation-specific SPR6 gene of Saccharomyces cerevisiae.

Kallal LA, Bhattacharyya M, Grove SN, Iannacone RF, Pugh TA, Primerano DA, Clancy MJ.

Curr Genet. 1990 Nov;18(4):293-301.

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