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Items: 42

1.

Deoxynucleoside therapy for thymidine kinase 2 (TK2) deficient myopathy.

Domínguez-González C, Madruga-Garrido M, Mavillard F, Garone C, Aguirre-Rodríguez FJ, Donati MA, Kleinsteuber K, Martí I, Martín-Hernández E, Morealejo-Aycinena JP, Munell F, Nascimento A, Kalko SG, Sardina MD, Del Vayo CÁ, Serrano O, Long Y, Tu Y, Levin B, Thompson JLP, Engelstad K, Uddin J, Torres-Torronteras J, Jimenez-Mallebrera C, Martí R, Paradas C, Hirano M.

Ann Neurol. 2019 May 24. doi: 10.1002/ana.25506. [Epub ahead of print]

PMID:
31125140
2.

Network modules uncover mechanisms of skeletal muscle dysfunction in COPD patients.

Tényi Á, Cano I, Marabita F, Kiani N, Kalko SG, Barreiro E, de Atauri P, Cascante M, Gomez-Cabrero D, Roca J.

J Transl Med. 2018 Feb 20;16(1):34. doi: 10.1186/s12967-018-1405-y.

3.

A 4-gene expression prognostic signature might guide post-remission therapy in patients with intermediate-risk cytogenetic acute myeloid leukemia.

Torrebadell M, Díaz-Beyá M, Kalko SG, Pratcorona M, Nomdedeu J, Navarro A, Gel B, Brunet S, Sierra J, Camós M, Esteve J.

Leuk Lymphoma. 2018 Oct;59(10):2394-2404. doi: 10.1080/10428194.2017.1422859. Epub 2018 Feb 2.

PMID:
29390924
4.

Multi-level differential network analysis of COPD exacerbations.

Noell G, Cosío BG, Faner R, Monsó E, Peces-Barba G, de Diego A, Esteban C, Gea J, Rodriguez-Roisin R, Garcia-Nuñez M, Pozo-Rodriguez F, Kalko SG, Agustí A.

Eur Respir J. 2017 Sep 27;50(3). pii: 1700075. doi: 10.1183/13993003.00075-2017. Print 2017 Sep.

5.

Effects of sex steroids on the pattern of methylation and expression of the promoter region of estrogen and androgen receptors in people with gender dysphoria under cross-sex hormone treatment.

Aranda G, Fernández-Rebollo E, Pradas-Juni M, Hanzu FA, Kalko SG, Halperin I, Mora M.

J Steroid Biochem Mol Biol. 2017 Sep;172:20-28. doi: 10.1016/j.jsbmb.2017.05.010. Epub 2017 May 21.

PMID:
28539237
6.

Altered Blood Gene Expression of Tumor-Related Genes (PRKCB, BECN1, and CDKN2A) in Alzheimer's Disease.

Antonell A, Lladó A, Sánchez-Valle R, Sanfeliu C, Casserras T, Rami L, Muñoz-García C, Dangla-Valls A, Balasa M, Boya P, Kalko SG, Molinuevo JL.

Mol Neurobiol. 2016 Nov;53(9):5902-5911. doi: 10.1007/s12035-015-9483-9. Epub 2015 Oct 28.

7.

Characterization of Inflammatory Response in Acute-on-Chronic Liver Failure and Relationship with Prognosis.

Solé C, Solà E, Morales-Ruiz M, Fernàndez G, Huelin P, Graupera I, Moreira R, de Prada G, Ariza X, Pose E, Fabrellas N, Kalko SG, Jiménez W, Ginès P.

Sci Rep. 2016 Aug 31;6:32341. doi: 10.1038/srep32341.

8.

GDF-15 Is Elevated in Children with Mitochondrial Diseases and Is Induced by Mitochondrial Dysfunction.

Montero R, Yubero D, Villarroya J, Henares D, Jou C, Rodríguez MA, Ramos F, Nascimento A, Ortez CI, Campistol J, Perez-Dueñas B, O'Callaghan M, Pineda M, Garcia-Cazorla A, Oferil JC, Montoya J, Ruiz-Pesini E, Emperador S, Meznaric M, Campderros L, Kalko SG, Villarroya F, Artuch R, Jimenez-Mallebrera C.

PLoS One. 2016 Feb 11;11(2):e0148709. doi: 10.1371/journal.pone.0148709. eCollection 2016. Erratum in: PLoS One. 2016;11(5):e0155172.

9.

Network Analysis of Lung Transcriptomics Reveals a Distinct B-Cell Signature in Emphysema.

Faner R, Cruz T, Casserras T, López-Giraldo A, Noell G, Coca I, Tal-Singer R, Miller B, Rodriguez-Roisin R, Spira A, Kalko SG, Agustí A.

Am J Respir Crit Care Med. 2016 Jun 1;193(11):1242-53. doi: 10.1164/rccm.201507-1311OC.

PMID:
26735770
10.

Transcriptome Analysis of Ullrich Congenital Muscular Dystrophy Fibroblasts Reveals a Disease Extracellular Matrix Signature and Key Molecular Regulators.

Paco S, Casserras T, Rodríguez MA, Jou C, Puigdelloses M, Ortez CI, Diaz-Manera J, Gallardo E, Colomer J, Nascimento A, Kalko SG, Jimenez-Mallebrera C.

PLoS One. 2015 Dec 15;10(12):e0145107. doi: 10.1371/journal.pone.0145107. eCollection 2015.

11.

Improving Assessment of Lipoprotein Profile in Type 1 Diabetes by 1H NMR Spectroscopy.

Brugnara L, Mallol R, Ribalta J, Vinaixa M, Murillo S, Casserras T, Guardiola M, Vallvé JC, Kalko SG, Correig X, Novials A.

PLoS One. 2015 Aug 28;10(8):e0136348. doi: 10.1371/journal.pone.0136348. eCollection 2015.

12.

Correction: Gene Expression Profiling Identifies Molecular Pathways Associated with Collagen VI Deficiency and Provides Novel Therapeutic Targets.

Paco S, Kalko SG, Jou C, Rodríguez MA, Corbera J, Muntoni F, Feng L, Rivas E, Torner F, Gualandi F, Gomez-Foix AM, Ferrer A, Ortez C, Nascimento A, Colomer J, Jimenez-Mallebrera C.

PLoS One. 2015 May 14;10(5):e0128614. doi: 10.1371/journal.pone.0128614. eCollection 2015. No abstract available.

13.

Systemic inflammatory response to smoking in chronic obstructive pulmonary disease: evidence of a gender effect.

Faner R, Gonzalez N, Cruz T, Kalko SG, Agustí A.

PLoS One. 2014 May 15;9(5):e97491. doi: 10.1371/journal.pone.0097491. eCollection 2014.

14.

Disruption of follicular dendritic cells-follicular lymphoma cross-talk by the pan-PI3K inhibitor BKM120 (Buparlisib).

Matas-Céspedes A, Rodriguez V, Kalko SG, Vidal-Crespo A, Rosich L, Casserras T, Balsas P, Villamor N, Giné E, Campo E, Roué G, López-Guillermo A, Colomer D, Pérez-Galán P.

Clin Cancer Res. 2014 Jul 1;20(13):3458-71. doi: 10.1158/1078-0432.CCR-14-0154. Epub 2014 May 5.

15.

In utero undernutrition in male mice programs liver lipid metabolism in the second-generation offspring involving altered Lxra DNA methylation.

Martínez D, Pentinat T, Ribó S, Daviaud C, Bloks VW, Cebrià J, Villalmanzo N, Kalko SG, Ramón-Krauel M, Díaz R, Plösch T, Tost J, Jiménez-Chillarón JC.

Cell Metab. 2014 Jun 3;19(6):941-51. doi: 10.1016/j.cmet.2014.03.026. Epub 2014 May 1.

16.

Integrative analysis reveals novel pathways mediating the interaction between adipose tissue and pancreatic islets in obesity in rats.

Malpique R, Figueiredo H, Esteban Y, Rebuffat SA, Hanzu FA, Vinaixa M, Yanes O, Correig X, Barceló-Batllori S, Gasa R, Kalko SG, Gomis R.

Diabetologia. 2014 Jun;57(6):1219-31. doi: 10.1007/s00125-014-3205-0. Epub 2014 Mar 15.

PMID:
24633677
17.

Synergistic anti-tumor activity of acadesine (AICAR) in combination with the anti-CD20 monoclonal antibody rituximab in in vivo and in vitro models of mantle cell lymphoma.

Montraveta A, Xargay-Torrent S, López-Guerra M, Rosich L, Pérez-Galán P, Salaverria I, Beà S, Kalko SG, de Frias M, Campàs C, Roué G, Colomer D.

Oncotarget. 2014 Feb 15;5(3):726-39.

18.

Transcriptomic profiling of TK2 deficient human skeletal muscle suggests a role for the p53 signalling pathway and identifies growth and differentiation factor-15 as a potential novel biomarker for mitochondrial myopathies.

Kalko SG, Paco S, Jou C, Rodríguez MA, Meznaric M, Rogac M, Jekovec-Vrhovsek M, Sciacco M, Moggio M, Fagiolari G, De Paepe B, De Meirleir L, Ferrer I, Roig-Quilis M, Munell F, Montoya J, López-Gallardo E, Ruiz-Pesini E, Artuch R, Montero R, Torner F, Nascimento A, Ortez C, Colomer J, Jimenez-Mallebrera C.

BMC Genomics. 2014 Feb 1;15:91. doi: 10.1186/1471-2164-15-91.

19.

Tungstate promotes β-cell survival in Irs2-/- mice.

Oliveira JM, Rebuffat SA, Gasa R, Burks DJ, Garcia A, Kalko SG, Zafra D, Guinovart JJ, Gomis R.

Am J Physiol Endocrinol Metab. 2014 Jan 1;306(1):E36-47. doi: 10.1152/ajpendo.00409.2013. Epub 2013 Nov 19.

20.

Gene expression profiling identifies molecular pathways associated with collagen VI deficiency and provides novel therapeutic targets.

Paco S, Kalko SG, Jou C, Rodríguez MA, Corbera J, Muntoni F, Feng L, Rivas E, Torner F, Gualandi F, Gomez-Foix AM, Ferrer A, Ortez C, Nascimento A, Colomer J, Jimenez-Mallebrera C.

PLoS One. 2013 Oct 11;8(10):e77430. doi: 10.1371/journal.pone.0077430. eCollection 2013. Erratum in: PLoS One. 2015;10(5):e0128614.

21.

Differential gene expression profile associated to apoptosis induced by dexamethasone in CLL cells according to IGHV/ZAP-70 status.

Baptista MJ, Muntañola A, Calpe E, Abrisqueta P, Salamero O, Fernández E, Codony C, Giné E, Kalko SG, Crespo M, Bosch F.

Clin Cancer Res. 2012 Nov 1;18(21):5924-33. doi: 10.1158/1078-0432.CCR-11-2771. Epub 2012 Sep 10.

22.

Identification of docetaxel resistance genes in castration-resistant prostate cancer.

Marín-Aguilera M, Codony-Servat J, Kalko SG, Fernández PL, Bermudo R, Buxo E, Ribal MJ, Gascón P, Mellado B.

Mol Cancer Ther. 2012 Feb;11(2):329-39. doi: 10.1158/1535-7163.MCT-11-0289. Epub 2011 Oct 25.

23.

Glucocorticoid alternative effects on proliferating and differentiated mammary epithelium are associated to opposite regulation of cell-cycle inhibitor expression.

Hoijman E, Rocha-Viegas L, Kalko SG, Rubinstein N, Morales-Ruiz M, Joffé EB, Kordon EC, Pecci A.

J Cell Physiol. 2012 Apr;227(4):1721-30. doi: 10.1002/jcp.22896.

PMID:
21688264
24.

Translational evidence of endothelial damage in obese individuals: inflammatory and prothrombotic responses.

Hanzu FA, Palomo M, Kalko SG, Parrizas M, Garaulet M, Escolar G, Gomis R, Diaz-Ricart M.

J Thromb Haemost. 2011 Jun;9(6):1236-45. doi: 10.1111/j.1538-7836.2011.04285.x.

25.

Knowledge management for systems biology a general and visually driven framework applied to translational medicine.

Maier D, Kalus W, Wolff M, Kalko SG, Roca J, Marin de Mas I, Turan N, Cascante M, Falciani F, Hernandez M, Villà-Freixa J, Losko S.

BMC Syst Biol. 2011 Mar 5;5:38. doi: 10.1186/1752-0509-5-38.

26.

Urine proteomics to detect biomarkers for chronic allograft dysfunction.

Quintana LF, Solé-Gonzalez A, Kalko SG, Bañon-Maneus E, Solé M, Diekmann F, Gutierrez-Dalmau A, Abian J, Campistol JM.

J Am Soc Nephrol. 2009 Feb;20(2):428-35. doi: 10.1681/ASN.2007101137. Epub 2008 Dec 3.

27.

Chronic non-spherocytic hemolytic anemia associated with severe neurological disease due to gamma-glutamylcysteine synthetase deficiency in a patient of Moroccan origin.

Mañú Pereira M, Gelbart T, Ristoff E, Crain KC, Bergua JM, López Lafuente A, Kalko SG, García Mateos E, Beutler E, Vives Corrons JL.

Haematologica. 2007 Nov;92(11):e102-5.

28.

Integration of DIGE and bioinformatics analyses reveals a role of the antiobesity agent tungstate in redox and energy homeostasis pathways in brown adipose tissue.

Barceló-Batllori S, Kalko SG, Esteban Y, Moreno S, Carmona MC, Gomis R.

Mol Cell Proteomics. 2008 Feb;7(2):378-93. Epub 2007 Nov 5. Erratum in: Mol Cell Proteomics. 2008 Jun;7(6):1188.

29.

AMarge: Automated Extensive Quality Assessment of Affymetrix chips.

Lozano JJ, Kalko SG.

Appl Bioinformatics. 2006;5(1):45-7.

PMID:
16539537
30.

Two new phosphoglycerate kinase mutations associated with chronic haemolytic anaemia and neurological dysfunction in two patients from Spain.

Noel N, Flanagan JM, Ramirez Bajo MJ, Kalko SG, Mañú Mdel M, Garcia Fuster JL, Perez de la Ossa P, Carreras J, Beutler E, Vives Corrons JL.

Br J Haematol. 2006 Feb;132(4):523-9. Erratum in: Br J Haematol. 2006 May;133(4):451. Flanagan, John [corrected to Flanagan, Jonathan M]; Perez de la Ossa, Pablo [added]; Carreras, Josep [added].

PMID:
16412025
31.

CD229 (Ly9) lymphocyte cell surface receptor interacts homophilically through its N-terminal domain and relocalizes to the immunological synapse.

Romero X, Zapater N, Calvo M, Kalko SG, de la Fuente MA, Tovar V, Ockeloen C, Pizcueta P, Engel P.

J Immunol. 2005 Jun 1;174(11):7033-42.

32.

Theoretical study of the truncated hemoglobin HbN: exploring the molecular basis of the NO detoxification mechanism.

Crespo A, Martí MA, Kalko SG, Morreale A, Orozco M, Gelpi JL, Luque FJ, Estrin DA.

J Am Chem Soc. 2005 Mar 30;127(12):4433-44.

PMID:
15783226
33.

Effect of bulky lesions on DNA: solution structure of a DNA duplex containing a cholesterol adduct.

Gómez-Pinto I, Cubero E, Kalko SG, Monaco V, van der Marel G, van Boom JH, Orozco M, González C.

J Biol Chem. 2004 Jun 4;279(23):24552-60. Epub 2004 Mar 31.

34.

The structure and dynamics of DNA in the gas phase.

Rueda M, Kalko SG, Luque FJ, Orozco M.

J Am Chem Soc. 2003 Jul 2;125(26):8007-14.

PMID:
12823023
35.

Theoretical studies on the inhibition mechanism of cyclooxygenase-2. Is there a unique recognition site?

Soliva R, Almansa C, Kalko SG, Luque FJ, Orozco M.

J Med Chem. 2003 Apr 10;46(8):1372-82.

PMID:
12672237
36.

Rational design of reversible acetylcholinesterase inhibitors.

Barril X, Kalko SG, Orozco M, Luque FJ.

Mini Rev Med Chem. 2002 Feb;2(1):27-36. Review.

PMID:
12369955
37.

Classical molecular interaction potentials: improved setup procedure in molecular dynamics simulations of proteins.

Gelpí JL, Kalko SG, Barril X, Cirera J, de La Cruz X, Luque FJ, Orozco M.

Proteins. 2001 Dec 1;45(4):428-37.

PMID:
11746690
38.

Theoretical study of the mechanisms of substrate recognition by catalase.

Kalko SG, Gelpí JL, Fita I, Orozco M.

J Am Chem Soc. 2001 Oct 3;123(39):9665-72.

PMID:
11572688
39.

The need for a shared database infrastructure: combining X-ray crystallography and electron microscopy.

Kalko SG, Chagoyen M, Jiménez-Lozano N, Verdaguer N, Fita I, Carazo JM.

Eur Biophys J. 2000;29(6):457-62.

PMID:
11081407
40.

A multiply substituted G-H loop from foot-and-mouth disease virus in complex with a neutralizing antibody: a role for water molecules.

Ochoa WF, Kalko SG, Mateu MG, Gomes P, Andreu D, Domingo E, Fita I, Verdaguer N.

J Gen Virol. 2000 Jun;81(Pt 6):1495-505.

PMID:
10811933
41.

Osmotic permeability in a molecular dynamics simulation of water transport through a single-occupancy pore.

Kalko SG, Hernández JA, Grigera JR, Fischbarg J.

Biochim Biophys Acta. 1995 Dec 13;1240(2):159-66.

42.

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