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Items: 1 to 50 of 61

1.

Effect of MUC1 length polymorphisms on the NLRP3 inflammasome response of human macrophages.

Dhar P, Sarkar S, Ng GZ, Kalitsis P, Saeed MA, McGuckin MA, Ellis JA, Sutton P.

Hum Immunol. 2019 Oct;80(10):878-882. doi: 10.1016/j.humimm.2019.06.001. Epub 2019 Jun 15.

PMID:
31213370
2.

Knocking in Multifunctional Gene Tags into SMC Complex Subunits Using Gene Editing.

Kalitsis P, Zhang T, Kim JH, Nielsen CF, Marshall KM, Hudson DF.

Methods Mol Biol. 2019;2004:91-102. doi: 10.1007/978-1-4939-9520-2_8.

PMID:
31147912
3.

A Roberts Syndrome Individual With Differential Genotoxin Sensitivity and a DNA Damage Response Defect.

McKay MJ, Craig J, Kalitsis P, Kozlov S, Verschoor S, Chen P, Lobachevsky P, Vasireddy R, Yan Y, Ryan J, McGillivray G, Savarirayan R, Lavin MF, Ramsay RG, Xu H.

Int J Radiat Oncol Biol Phys. 2019 Apr 1;103(5):1194-1202. doi: 10.1016/j.ijrobp.2018.11.047. Epub 2018 Nov 30.

PMID:
30508616
4.

Restricted cell cycle is essential for clonal evolution and therapeutic resistance of pre-leukemic stem cells.

Tremblay CS, Saw J, Chiu SK, Wong NC, Tsyganov K, Ghotb S, Graham AN, Yan F, Guirguis AA, Sonderegger SE, Lee N, Kalitsis P, Reynolds J, Ting SB, Powell DR, Jane SM, Curtis DJ.

Nat Commun. 2018 Aug 30;9(1):3535. doi: 10.1038/s41467-018-06021-7.

5.

Correction to: Polymyxin B causes DNA damage in HK-2 cells and mice.

Yun B, Zhang T, Azad MAK, Wang J, Nowell CJ, Kalitsis P, Velkov T, Hudson DF, Li J.

Arch Toxicol. 2018 Jul;92(7):2273-2274. doi: 10.1007/s00204-018-2233-9.

PMID:
29916052
6.

Ribosomal DNA copy loss and repeat instability in ATRX-mutated cancers.

Udugama M, Sanij E, Voon HPJ, Son J, Hii L, Henson JD, Chan FL, Chang FTM, Liu Y, Pearson RB, Kalitsis P, Mann JR, Collas P, Hannan RD, Wong LH.

Proc Natl Acad Sci U S A. 2018 May 1;115(18):4737-4742. doi: 10.1073/pnas.1720391115. Epub 2018 Apr 18.

7.

Polymyxin B causes DNA damage in HK-2 cells and mice.

Yun B, Zhang T, Azad MAK, Wang J, Nowell CJ, Kalitsis P, Velkov T, Hudson DF, Li J.

Arch Toxicol. 2018 Jul;92(7):2259-2271. doi: 10.1007/s00204-018-2192-1. Epub 2018 Mar 20. Erratum in: Arch Toxicol. 2018 Jun 18;:.

8.

Identification of an Immortalized Human Airway Epithelial Cell Line with Dyskinetic Cilia.

Kuek LE, Griffin P, Martinello P, Graham AN, Kalitsis P, Robinson PJ, Mackay GA.

Am J Respir Cell Mol Biol. 2018 Sep;59(3):375-382. doi: 10.1165/rcmb.2017-0188OC.

PMID:
29481304
9.

The Role of Centromere Defects in Cancer.

Beh TT, Kalitsis P.

Prog Mol Subcell Biol. 2017;56:541-554. doi: 10.1007/978-3-319-58592-5_22. Review.

PMID:
28840252
10.

Condensin, master organizer of the genome.

Kalitsis P, Zhang T, Marshall KM, Nielsen CF, Hudson DF.

Chromosome Res. 2017 Mar;25(1):61-76. doi: 10.1007/s10577-017-9553-0. Epub 2017 Feb 9. Review.

PMID:
28181049
11.

Loss of RMI2 Increases Genome Instability and Causes a Bloom-Like Syndrome.

Hudson DF, Amor DJ, Boys A, Butler K, Williams L, Zhang T, Kalitsis P.

PLoS Genet. 2016 Dec 15;12(12):e1006483. doi: 10.1371/journal.pgen.1006483. eCollection 2016 Dec.

12.

Active centromere and chromosome identification in fixed cell lines.

Beh TT, MacKinnon RN, Kalitsis P.

Mol Cytogenet. 2016 Mar 22;9:28. doi: 10.1186/s13039-016-0236-x. eCollection 2016.

13.

Condensin I and II behaviour in interphase nuclei and cells undergoing premature chromosome condensation.

Zhang T, Paulson JR, Bakhrebah M, Kim JH, Nowell C, Kalitsis P, Hudson DF.

Chromosome Res. 2016 May;24(2):243-69. doi: 10.1007/s10577-016-9519-7. Epub 2016 Mar 23.

PMID:
27008552
14.

Activation by zinc of the human gastrin gene promoter in colon cancer cells in vitro and in vivo.

Marshall KM, Laval M, Estacio O, Hudson DF, Kalitsis P, Shulkes A, Baldwin GS, Patel O.

Metallomics. 2015 Oct;7(10):1390-8. doi: 10.1039/c5mt00147a. Epub 2015 Sep 25.

PMID:
26404630
15.

Contribution of the two genes encoding histone variant h3.3 to viability and fertility in mice.

Tang MC, Jacobs SA, Mattiske DM, Soh YM, Graham AN, Tran A, Lim SL, Hudson DF, Kalitsis P, O'Bryan MK, Wong LH, Mann JR.

PLoS Genet. 2015 Feb 12;11(2):e1004964. doi: 10.1371/journal.pgen.1004964. eCollection 2015 Feb.

16.

Disruption of a conserved CAP-D3 threonine alters condensin loading on mitotic chromosomes leading to chromosome hypercondensation.

Bakhrebah M, Zhang T, Mann JR, Kalitsis P, Hudson DF.

J Biol Chem. 2015 Mar 6;290(10):6156-67. doi: 10.1074/jbc.M114.627109. Epub 2015 Jan 20.

17.

Chromosome Y centromere array deletion leads to impaired centromere function.

Graham AN, Kalitsis P.

PLoS One. 2014 Jan 22;9(1):e86875. doi: 10.1371/journal.pone.0086875. eCollection 2014.

18.

Condensin I associates with structural and gene regulatory regions in vertebrate chromosomes.

Kim JH, Zhang T, Wong NC, Davidson N, Maksimovic J, Oshlack A, Earnshaw WC, Kalitsis P, Hudson DF.

Nat Commun. 2013;4:2537. doi: 10.1038/ncomms3537.

19.

Normal DNA methylation dynamics in DICER1-deficient mouse embryonic stem cells.

Ip J, Canham P, Choo KH, Inaba Y, Jacobs SA, Kalitsis P, Mattiske DM, Ng J, Saffery R, Wong NC, Wong LH, Mann JR.

PLoS Genet. 2012 Sep;8(9):e1002919. doi: 10.1371/journal.pgen.1002919. Epub 2012 Sep 6.

20.

The evolutionary life cycle of the resilient centromere.

Kalitsis P, Choo KH.

Chromosoma. 2012 Aug;121(4):327-40. doi: 10.1007/s00412-012-0369-6. Epub 2012 Apr 11. Review.

PMID:
22527114
21.

Contrasting roles of condensin I and condensin II in mitotic chromosome formation.

Green LC, Kalitsis P, Chang TM, Cipetic M, Kim JH, Marshall O, Turnbull L, Whitchurch CB, Vagnarelli P, Samejima K, Earnshaw WC, Choo KH, Hudson DF.

J Cell Sci. 2012 Mar 15;125(Pt 6):1591-604. doi: 10.1242/jcs.097790. Epub 2012 Feb 17.

22.

Streptavidin-Binding Peptide (SBP)-tagged SMC2 allows single-step affinity fluorescence, blotting or purification of the condensin complex.

Kim JH, Chang TM, Graham AN, Choo KH, Kalitsis P, Hudson DF.

BMC Biochem. 2010 Dec 31;11:50. doi: 10.1186/1471-2091-11-50.

23.
24.

Small CGG repeat expansion alleles of FMR1 gene are associated with parkinsonism.

Loesch DZ, Khaniani MS, Slater HR, Rubio JP, Bui QM, Kotschet K, D'Souza W, Venn A, Kalitsis P, Choo AK, Burgess T, Johnson L, Evans A, Horne M.

Clin Genet. 2009 Nov;76(5):471-6. doi: 10.1111/j.1399-0004.2009.01275.x. Epub 2009 Sep 30.

25.

Orchestrating twosome and foursome chromosome parties.

Kalitsis P, Choo KH.

Dev Cell. 2009 Sep;17(3):305-7. doi: 10.1016/j.devcel.2009.08.013.

26.

Rapid evolution of mouse Y centromere repeat DNA belies recent sequence stability.

Pertile MD, Graham AN, Choo KH, Kalitsis P.

Genome Res. 2009 Dec;19(12):2202-13. doi: 10.1101/gr.092080.109. Epub 2009 Sep 8.

27.

An improved Diagnostic PCR Assay for identification of Cryptic Heterozygosity for CGG Triplet Repeat Alleles in the Fragile X Gene (FMR1).

Khaniani MS, Kalitsis P, Burgess T, Slater HR.

Mol Cytogenet. 2008 Apr 8;1:5. doi: 10.1186/1755-8166-1-5.

28.

ZNF397, a new class of interphase to early prophase-specific, SCAN-zinc-finger, mammalian centromere protein.

Bailey SL, Chang SC, Griffiths B, Graham AN, Saffery R, Earle E, Choo KH, Kalitsis P.

Chromosoma. 2008 Aug;117(4):367-80. doi: 10.1007/s00412-008-0155-7. Epub 2008 Mar 28.

PMID:
18369653
29.

Mouse telocentric sequences reveal a high rate of homogenization and possible role in Robertsonian translocation.

Kalitsis P, Griffiths B, Choo KH.

Proc Natl Acad Sci U S A. 2006 Jun 6;103(23):8786-91. Epub 2006 May 26.

30.

Spef1, a conserved novel testis protein found in mouse sperm flagella.

Chan SW, Fowler KJ, Choo KH, Kalitsis P.

Gene. 2005 Jul 4;353(2):189-99.

PMID:
15979255
31.

Increased chromosome instability but not cancer predisposition in haploinsufficient Bub3 mice.

Kalitsis P, Fowler KJ, Griffiths B, Earle E, Chow CW, Jamsen K, Choo KH.

Genes Chromosomes Cancer. 2005 Sep;44(1):29-36.

PMID:
15898111
32.

Building the centromere: from foundation proteins to 3D organization.

Amor DJ, Kalitsis P, Sumer H, Choo KH.

Trends Cell Biol. 2004 Jul;14(7):359-68. Review.

PMID:
15246429
33.

Partially functional Cenpa-GFP fusion protein causes increased chromosome missegregation and apoptosis during mouse embryogenesis.

Kalitsis P, Fowler KJ, Earle E, Griffiths B, Howman E, Newson AJ, Choo KH.

Chromosome Res. 2003;11(4):345-57.

PMID:
12906131
34.

Poly(ADP-ribose) polymerase 2 localizes to mammalian active centromeres and interacts with PARP-1, Cenpa, Cenpb and Bub3, but not Cenpc.

Saxena A, Wong LH, Kalitsis P, Earle E, Shaffer LG, Choo KH.

Hum Mol Genet. 2002 Sep 15;11(19):2319-29.

PMID:
12217960
35.

Centromere proteins Cenpa, Cenpb, and Bub3 interact with poly(ADP-ribose) polymerase-1 protein and are poly(ADP-ribosyl)ated.

Saxena A, Saffery R, Wong LH, Kalitsis P, Choo KH.

J Biol Chem. 2002 Jul 26;277(30):26921-6. Epub 2002 May 13.

36.

A 330 kb CENP-A binding domain and altered replication timing at a human neocentromere.

Lo AW, Craig JM, Saffery R, Kalitsis P, Irvine DV, Earle E, Magliano DJ, Choo KH.

EMBO J. 2001 Apr 17;20(8):2087-96.

37.

A novel chromatin immunoprecipitation and array (CIA) analysis identifies a 460-kb CENP-A-binding neocentromere DNA.

Lo AW, Magliano DJ, Sibson MC, Kalitsis P, Craig JM, Choo KH.

Genome Res. 2001 Mar;11(3):448-57.

38.

Components of the human spindle checkpoint control mechanism localize specifically to the active centromere on dicentric chromosomes.

Saffery R, Irvine DV, Griffiths B, Kalitsis P, Choo KH.

Hum Genet. 2000 Oct;107(4):376-84.

PMID:
11129339
39.

Assignment of the centromere protein H (Cenph) gene to mouse chromosome band 13D1 by in situ hybridization and interspecific backcross analyses.

Lo AW, Longmuir DF, Fowler KJ, Kalitsis P, Choo KH.

Cytogenet Cell Genet. 2000;90(1-2):56-7. No abstract available.

PMID:
11060445
40.
41.

Early disruption of centromeric chromatin organization in centromere protein A (Cenpa) null mice.

Howman EV, Fowler KJ, Newson AJ, Redward S, MacDonald AC, Kalitsis P, Choo KH.

Proc Natl Acad Sci U S A. 2000 Feb 1;97(3):1148-53.

42.

Mouse mitotic spindle checkpoint Bub3 gene maps to the distal region of chromosome 7 by interspecific backcross analysis.

Fowler KJ, Kalitsis P, Choo KH.

Cytogenet Cell Genet. 1999;87(1-2):91-2. No abstract available.

PMID:
10640819
43.

Human centromeres and neocentromeres show identical distribution patterns of >20 functionally important kinetochore-associated proteins.

Saffery R, Irvine DV, Griffiths B, Kalitsis P, Wordeman L, Choo KH.

Hum Mol Genet. 2000 Jan 22;9(2):175-85.

PMID:
10607828
44.

Conservation of centromere protein in vertebrates.

Saffery R, Earle E, Irvine DV, Kalitsis P, Choo KH.

Chromosome Res. 1999;7(4):261-5.

PMID:
10461871
45.

Trisomy 20p resulting from inverted duplication and neocentromere formation.

Voullaire L, Saffery R, Davies J, Earle E, Kalitsis P, Slater H, Irvine DV, Choo KH.

Am J Med Genet. 1999 Aug 6;85(4):403-8.

PMID:
10398268
46.

Defective chromosome segregation, microtubule bundling and nuclear bridging in inner centromere protein gene (Incenp)-disrupted mice.

Cutts SM, Fowler KJ, Kile BT, Hii LL, O'Dowd RA, Hudson DF, Saffery R, Kalitsis P, Earle E, Choo KH.

Hum Mol Genet. 1999 Jul;8(7):1145-55.

PMID:
10369859
47.

Centromere protein B null mice are mitotically and meiotically normal but have lower body and testis weights.

Hudson DF, Fowler KJ, Earle E, Saffery R, Kalitsis P, Trowell H, Hill J, Wreford NG, de Kretser DM, Cancilla MR, Howman E, Hii L, Cutts SM, Irvine DV, Choo KH.

J Cell Biol. 1998 Apr 20;141(2):309-19.

48.

Targeted disruption of mouse centromere protein C gene leads to mitotic disarray and early embryo death.

Kalitsis P, Fowler KJ, Earle E, Hill J, Choo KH.

Proc Natl Acad Sci U S A. 1998 Feb 3;95(3):1136-41.

49.

Gene structure and sequence analysis of mouse centromere proteins A and C.

Kalitsis P, MacDonald AC, Newson AJ, Hudson DF, Choo KH.

Genomics. 1998 Jan 1;47(1):108-14.

PMID:
9465302
50.

A functional neo-centromere formed through activation of a latent human centromere and consisting of non-alpha-satellite DNA.

du Sart D, Cancilla MR, Earle E, Mao JI, Saffery R, Tainton KM, Kalitsis P, Martyn J, Barry AE, Choo KH.

Nat Genet. 1997 Jun;16(2):144-53.

PMID:
9171825

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