Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 99


Identification of a novel arthritis-associated osteoclast precursor macrophage regulated by FoxM1.

Hasegawa T, Kikuta J, Sudo T, Matsuura Y, Matsui T, Simmons S, Ebina K, Hirao M, Okuzaki D, Yoshida Y, Hirao A, Kalinichenko VV, Yamaoka K, Takeuchi T, Ishii M.

Nat Immunol. 2019 Dec;20(12):1631-1643. doi: 10.1038/s41590-019-0526-7. Epub 2019 Nov 18.


Forkhead Box M1 Transcription Factor Drives Liver Inflammation Linking to Hepatocarcinogenesis in Mice.

Kurahashi T, Yoshida Y, Ogura S, Egawa M, Furuta K, Hikita H, Kodama T, Sakamori R, Kiso S, Kamada Y, Wang IC, Eguchi H, Morii E, Doki Y, Mori M, Kalinichenko VV, Tatsumi T, Takehara T.

Cell Mol Gastroenterol Hepatol. 2019 Oct 24;9(3):425-446. doi: 10.1016/j.jcmgh.2019.10.008. [Epub ahead of print]


Molecular, cellular, and bioengineering approaches to stimulate lung regeneration after injury.

Bolte C, Kalin TV, Kalinichenko VV.

Semin Cell Dev Biol. 2019 Oct 25. pii: S1084-9521(18)30286-6. doi: 10.1016/j.semcdb.2019.10.006. [Epub ahead of print] Review.


Postnatal Alveologenesis Depends on FOXF1 Signaling in c-KIT+ Endothelial Progenitor Cells.

Ren X, Ustiyan V, Guo M, Wang G, Bolte C, Zhang Y, Xu Y, Whitsett JA, Kalin TV, Kalinichenko VV.

Am J Respir Crit Care Med. 2019 Nov 1;200(9):1164-1176. doi: 10.1164/rccm.201812-2312OC.


The S52F FOXF1 Mutation Inhibits STAT3 Signaling and Causes Alveolar Capillary Dysplasia.

Pradhan A, Dunn A, Ustiyan V, Bolte C, Wang G, Whitsett JA, Zhang Y, Porollo A, Hu YC, Xiao R, Szafranski P, Shi D, Stankiewicz P, Kalin TV, Kalinichenko VV.

Am J Respir Crit Care Med. 2019 Oct 15;200(8):1045-1056. doi: 10.1164/rccm.201810-1897OC.


The FOXM1 Inhibitor RCM-1 Decreases Carcinogenesis and Nuclear β-Catenin.

Shukla S, Milewski D, Pradhan A, Rama N, Rice K, Le T, Flick MJ, Vaz S, Zhao X, Setchell KD, Logarinho E, Kalinichenko VV, Kalin TV.

Mol Cancer Ther. 2019 Jul;18(7):1217-1229. doi: 10.1158/1535-7163.MCT-18-0709. Epub 2019 Apr 30.


The Forkhead box F1 transcription factor inhibits collagen deposition and accumulation of myofibroblasts during liver fibrosis.

Flood HM, Bolte C, Dasgupta N, Sharma A, Zhang Y, Gandhi CR, Kalin TV, Kalinichenko VV.

Biol Open. 2019 Feb 11;8(2). pii: bio039800. doi: 10.1242/bio.039800.


Vagus-macrophage-hepatocyte link promotes post-injury liver regeneration and whole-body survival through hepatic FoxM1 activation.

Izumi T, Imai J, Yamamoto J, Kawana Y, Endo A, Sugawara H, Kohata M, Asai Y, Takahashi K, Kodama S, Kaneko K, Gao J, Uno K, Sawada S, Kalinichenko VV, Ishigaki Y, Yamada T, Katagiri H.

Nat Commun. 2018 Dec 13;9(1):5300. doi: 10.1038/s41467-018-07747-0.


Building and Regenerating the Lung Cell by Cell.

Whitsett JA, Kalin TV, Xu Y, Kalinichenko VV.

Physiol Rev. 2019 Jan 1;99(1):513-554. doi: 10.1152/physrev.00001.2018. Review.


Highly Efficient In Vivo Targeting of the Pulmonary Endothelium Using Novel Modifications of Polyethylenimine: An Importance of Charge.

Dunn AW, Kalinichenko VV, Shi D.

Adv Healthc Mater. 2018 Dec;7(23):e1800876. doi: 10.1002/adhm.201800876. Epub 2018 Nov 6.


FOXF1 transcription factor promotes lung morphogenesis by inducing cellular proliferation in fetal lung mesenchyme.

Ustiyan V, Bolte C, Zhang Y, Han L, Xu Y, Yutzey KE, Zorn AM, Kalin TV, Shannon JM, Kalinichenko VV.

Dev Biol. 2018 Nov 1;443(1):50-63. doi: 10.1016/j.ydbio.2018.08.011. Epub 2018 Aug 25.


FOXF1 Inhibits Pulmonary Fibrosis by Preventing CDH2-CDH11 Cadherin Switch in Myofibroblasts.

Black M, Milewski D, Le T, Ren X, Xu Y, Kalinichenko VV, Kalin TV.

Cell Rep. 2018 Apr 10;23(2):442-458. doi: 10.1016/j.celrep.2018.03.067.


Transcription Factors Regulating Embryonic Development of Pulmonary Vasculature.

Bolte C, Whitsett JA, Kalin TV, Kalinichenko VV.

Adv Anat Embryol Cell Biol. 2018;228:1-20. doi: 10.1007/978-3-319-68483-3_1. Review.


FOXM1 activates AGR2 and causes progression of lung adenomas into invasive mucinous adenocarcinomas.

Milewski D, Balli D, Ustiyan V, Le T, Dienemann H, Warth A, Breuhahn K, Whitsett JA, Kalinichenko VV, Kalin TV.

PLoS Genet. 2017 Dec 21;13(12):e1007097. doi: 10.1371/journal.pgen.1007097. eCollection 2017 Dec.


Neuronal signals regulate obesity induced β-cell proliferation by FoxM1 dependent mechanism.

Yamamoto J, Imai J, Izumi T, Takahashi H, Kawana Y, Takahashi K, Kodama S, Kaneko K, Gao J, Uno K, Sawada S, Asano T, Kalinichenko VV, Susaki EA, Kanzaki M, Ueda HR, Ishigaki Y, Yamada T, Katagiri H.

Nat Commun. 2017 Dec 5;8(1):1930. doi: 10.1038/s41467-017-01869-7.


FOXF1 transcription factor promotes lung regeneration after partial pneumonectomy.

Bolte C, Flood HM, Ren X, Jagannathan S, Barski A, Kalin TV, Kalinichenko VV.

Sci Rep. 2017 Sep 6;7(1):10690. doi: 10.1038/s41598-017-11175-3.


The FOXM1 inhibitor RCM-1 suppresses goblet cell metaplasia and prevents IL-13 and STAT6 signaling in allergen-exposed mice.

Sun L, Ren X, Wang IC, Pradhan A, Zhang Y, Flood HM, Han B, Whitsett JA, Kalin TV, Kalinichenko VV.

Sci Signal. 2017 Apr 18;10(475). pii: eaai8583. doi: 10.1126/scisignal.aai8583.


Induction of Chromosome Instability by Activation of Yes-Associated Protein and Forkhead Box M1 in Liver Cancer.

Weiler SME, Pinna F, Wolf T, Lutz T, Geldiyev A, Sticht C, Knaub M, Thomann S, Bissinger M, Wan S, Rössler S, Becker D, Gretz N, Lang H, Bergmann F, Ustiyan V, Kalin TV, Singer S, Lee JS, Marquardt JU, Schirmacher P, Kalinichenko VV, Breuhahn K.

Gastroenterology. 2017 Jun;152(8):2037-2051.e22. doi: 10.1053/j.gastro.2017.02.018. Epub 2017 Feb 27.


Correction: Foxf Genes Integrate Tbx5 and Hedgehog Pathways in the Second Heart Field for Cardiac Septation.

Hoffmann AD, Yang XH, Burnicka-Turek O, Bosman JD, Ren X, Xie L, Steimle JD, Vokes SA, McMahon AP, Kalinichenko VV, Moskowitz IP.

PLoS Genet. 2016 Dec 29;12(12):e1006533. doi: 10.1371/journal.pgen.1006533. eCollection 2016 Dec.


Lethal lung hypoplasia and vascular defects in mice with conditional Foxf1 overexpression.

Dharmadhikari AV, Sun JJ, Gogolewski K, Carofino BL, Ustiyan V, Hill M, Majewski T, Szafranski P, Justice MJ, Ray RS, Dickinson ME, Kalinichenko VV, Gambin A, Stankiewicz P.

Biol Open. 2016 Nov 15;5(11):1595-1606. doi: 10.1242/bio.019208.


FoxF1 and FoxF2 transcription factors synergistically promote rhabdomyosarcoma carcinogenesis by repressing transcription of p21Cip1 CDK inhibitor.

Milewski D, Pradhan A, Wang X, Cai Y, Le T, Turpin B, Kalinichenko VV, Kalin TV.

Oncogene. 2017 Feb 9;36(6):850-862. doi: 10.1038/onc.2016.254. Epub 2016 Jul 18.


The transcription factor FOXF1 promotes prostate cancer by stimulating the mitogen-activated protein kinase ERK5.

Fulford L, Milewski D, Ustiyan V, Ravishankar N, Cai Y, Le T, Masineni S, Kasper S, Aronow B, Kalinichenko VV, Kalin TV.

Sci Signal. 2016 May 10;9(427):ra48. doi: 10.1126/scisignal.aad5582.


FOXF1 maintains endothelial barrier function and prevents edema after lung injury.

Cai Y, Bolte C, Le T, Goda C, Xu Y, Kalin TV, Kalinichenko VV.

Sci Signal. 2016 Apr 19;9(424):ra40. doi: 10.1126/scisignal.aad1899.


β-catenin and Kras/Foxm1 signaling pathway are critical to restrict Sox9 in basal cells during pulmonary branching morphogenesis.

Ustiyan V, Zhang Y, Perl AK, Whitsett JA, Kalin TV, Kalinichenko VV.

Dev Dyn. 2016 May;245(5):590-604. doi: 10.1002/dvdy.24393. Epub 2016 Mar 8.


A Shh-Foxf-Fgf18-Shh Molecular Circuit Regulating Palate Development.

Xu J, Liu H, Lan Y, Aronow BJ, Kalinichenko VV, Jiang R.

PLoS Genet. 2016 Jan 8;12(1):e1005769. doi: 10.1371/journal.pgen.1005769. eCollection 2016 Jan.


Forkhead transcription factor FoxF1 interacts with Fanconi anemia protein complexes to promote DNA damage response.

Pradhan A, Ustiyan V, Zhang Y, Kalin TV, Kalinichenko VV.

Oncotarget. 2016 Jan 12;7(2):1912-26. doi: 10.18632/oncotarget.6422.


Control of regional decidualization in implantation: Role of FoxM1 downstream of Hoxa10 and cyclin D3.

Gao F, Bian F, Ma X, Kalinichenko VV, Das SK.

Sci Rep. 2015 Sep 9;5:13863. doi: 10.1038/srep13863.


Genomic and Epigenetic Complexity of the FOXF1 Locus in 16q24.1: Implications for Development and Disease.

Dharmadhikari AV, Szafranski P, Kalinichenko VV, Stankiewicz P.

Curr Genomics. 2015 Apr;16(2):107-16. doi: 10.2174/1389202916666150122223252.


Is there potential to target FOXM1 for 'undruggable' lung cancers?

Kalinichenko VV, Kalin TV.

Expert Opin Ther Targets. 2015 Jul;19(7):865-7. doi: 10.1517/14728222.2015.1042366. Epub 2015 May 4.


Forkhead box F2 regulation of platelet-derived growth factor and myocardin/serum response factor signaling is essential for intestinal development.

Bolte C, Ren X, Tomley T, Ustiyan V, Pradhan A, Hoggatt A, Kalin TV, Herring BP, Kalinichenko VV.

J Biol Chem. 2015 Mar 20;290(12):7563-75. doi: 10.1074/jbc.M114.609487. Epub 2015 Jan 28.


Increased FOXM1 expression can stimulate DNA repair in normal hepatocytes in vivo but also increases nuclear foci associated with senescence.

Baranski OA, Kalinichenko VV, Adami GR.

Cell Prolif. 2015 Feb;48(1):105-15. doi: 10.1111/cpr.12153. Epub 2014 Dec 5.


Foxf genes integrate tbx5 and hedgehog pathways in the second heart field for cardiac septation.

Hoffmann AD, Yang XH, Burnicka-Turek O, Bosman JD, Ren X, Steimle JD, Vokes SA, McMahon AP, Kalinichenko VV, Moskowitz IP.

PLoS Genet. 2014 Oct 30;10(10):e1004604. doi: 10.1371/journal.pgen.1004604. eCollection 2014 Oct. Erratum in: PLoS Genet. 2016 Dec 29;12 (12 ):e1006533.


Foxm1 regulates resolution of hyperoxic lung injury in newborns.

Xia H, Ren X, Bolte CS, Ustiyan V, Zhang Y, Shah TA, Kalin TV, Whitsett JA, Kalinichenko VV.

Am J Respir Cell Mol Biol. 2015 May;52(5):611-21. doi: 10.1165/rcmb.2014-0091OC.


SPDEF inhibits prostate carcinogenesis by disrupting a positive feedback loop in regulation of the Foxm1 oncogene.

Cheng XH, Black M, Ustiyan V, Le T, Fulford L, Sridharan A, Medvedovic M, Kalinichenko VV, Whitsett JA, Kalin TV.

PLoS Genet. 2014 Sep 25;10(9):e1004656. doi: 10.1371/journal.pgen.1004656. eCollection 2014 Sep.


FOXF1 transcription factor is required for formation of embryonic vasculature by regulating VEGF signaling in endothelial cells.

Ren X, Ustiyan V, Pradhan A, Cai Y, Havrilak JA, Bolte CS, Shannon JM, Kalin TV, Kalinichenko VV.

Circ Res. 2014 Sep 26;115(8):709-20. doi: 10.1161/CIRCRESAHA.115.304382. Epub 2014 Aug 4.


Comparative analyses of lung transcriptomes in patients with alveolar capillary dysplasia with misalignment of pulmonary veins and in foxf1 heterozygous knockout mice.

Sen P, Dharmadhikari AV, Majewski T, Mohammad MA, Kalin TV, Zabielska J, Ren X, Bray M, Brown HM, Welty S, Thevananther S, Langston C, Szafranski P, Justice MJ, Kalinichenko VV, Gambin A, Belmont J, Stankiewicz P.

PLoS One. 2014 Apr 10;9(4):e94390. doi: 10.1371/journal.pone.0094390. eCollection 2014.


Grainyhead-like 2 (GRHL2) distribution reveals novel pathophysiological differences between human idiopathic pulmonary fibrosis and mouse models of pulmonary fibrosis.

Varma S, Mahavadi P, Sasikumar S, Cushing L, Hyland T, Rosser AE, Riccardi D, Lu J, Kalin TV, Kalinichenko VV, Guenther A, Ramirez MI, Pardo A, Selman M, Warburton D.

Am J Physiol Lung Cell Mol Physiol. 2014 Mar 1;306(5):L405-19. doi: 10.1152/ajplung.00143.2013. Epub 2013 Dec 27.


Foxm1 transcription factor is required for the initiation of lung tumorigenesis by oncogenic Kras(G12D.).

Wang IC, Ustiyan V, Zhang Y, Cai Y, Kalin TV, Kalinichenko VV.

Oncogene. 2014 Nov 13;33(46):5391-6. doi: 10.1038/onc.2013.475. Epub 2013 Nov 11.


The transcription factor Foxf1 binds to serum response factor and myocardin to regulate gene transcription in visceral smooth muscle cells.

Hoggatt AM, Kim JR, Ustiyan V, Ren X, Kalin TV, Kalinichenko VV, Herring BP.

J Biol Chem. 2013 Oct 4;288(40):28477-87. doi: 10.1074/jbc.M113.478974. Epub 2013 Aug 14.


Foxm1 transcription factor is required for lung fibrosis and epithelial-to-mesenchymal transition.

Balli D, Ustiyan V, Zhang Y, Wang IC, Masino AJ, Ren X, Whitsett JA, Kalinichenko VV, Kalin TV.

EMBO J. 2013 Jan 23;32(2):231-44. doi: 10.1038/emboj.2012.336. Epub 2013 Jan 4.


FoxO1 and FoxM1 transcription factors have antagonistic functions in neonatal cardiomyocyte cell-cycle withdrawal and IGF1 gene regulation.

Sengupta A, Kalinichenko VV, Yutzey KE.

Circ Res. 2013 Jan 18;112(2):267-77. doi: 10.1161/CIRCRESAHA.112.277442. Epub 2012 Nov 14.


FOXM1 promotes allergen-induced goblet cell metaplasia and pulmonary inflammation.

Ren X, Shah TA, Ustiyan V, Zhang Y, Shinn J, Chen G, Whitsett JA, Kalin TV, Kalinichenko VV.

Mol Cell Biol. 2013 Jan;33(2):371-86. doi: 10.1128/MCB.00934-12. Epub 2012 Nov 12.


Postnatal ablation of Foxm1 from cardiomyocytes causes late onset cardiac hypertrophy and fibrosis without exacerbating pressure overload-induced cardiac remodeling.

Bolte C, Zhang Y, York A, Kalin TV, Schultz Jel J, Molkentin JD, Kalinichenko VV.

PLoS One. 2012;7(11):e48713. doi: 10.1371/journal.pone.0048713. Epub 2012 Nov 8.


Foxm1 transcription factor is critical for proliferation and differentiation of Clara cells during development of conducting airways.

Ustiyan V, Wert SE, Ikegami M, Wang IC, Kalin TV, Whitsett JA, Kalinichenko VV.

Dev Biol. 2012 Oct 15;370(2):198-212. doi: 10.1016/j.ydbio.2012.07.028. Epub 2012 Aug 2.


Foxm1 mediates cross talk between Kras/mitogen-activated protein kinase and canonical Wnt pathways during development of respiratory epithelium.

Wang IC, Snyder J, Zhang Y, Lander J, Nakafuku Y, Lin J, Chen G, Kalin TV, Whitsett JA, Kalinichenko VV.

Mol Cell Biol. 2012 Oct;32(19):3838-50. doi: 10.1128/MCB.00355-12. Epub 2012 Jul 23.


Foxm1 transcription factor is required for macrophage migration during lung inflammation and tumor formation.

Balli D, Ren X, Chou FS, Cross E, Zhang Y, Kalinichenko VV, Kalin TV.

Oncogene. 2012 Aug 23;31(34):3875-88. doi: 10.1038/onc.2011.549. Epub 2011 Dec 5.


Expression of Foxm1 transcription factor in cardiomyocytes is required for myocardial development.

Bolte C, Zhang Y, Wang IC, Kalin TV, Molkentin JD, Kalinichenko VV.

PLoS One. 2011;6(7):e22217. doi: 10.1371/journal.pone.0022217. Epub 2011 Jul 14.


FoxM1 mediates the progenitor function of type II epithelial cells in repairing alveolar injury induced by Pseudomonas aeruginosa.

Liu Y, Sadikot RT, Adami GR, Kalinichenko VV, Pendyala S, Natarajan V, Zhao YY, Malik AB.

J Exp Med. 2011 Jul 4;208(7):1473-84. doi: 10.1084/jem.20102041. Epub 2011 Jun 27.


Integrin α6β4 defines a novel lung epithelial progenitor cell: a step forward for cell-based therapies for pulmonary disease.

Whitsett JA, Kalinichenko VV.

J Clin Invest. 2011 Jul;121(7):2543-5. doi: 10.1172/JCI58704. Epub 2011 Jun 23.


Notch and basal cells take center stage during airway epithelial regeneration.

Whitsett JA, Kalinichenko VV.

Cell Stem Cell. 2011 Jun 3;8(6):597-8. doi: 10.1016/j.stem.2011.05.008.

Supplemental Content

Loading ...
Support Center