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Items: 42

1.

Identification of molecular signatures of cystic fibrosis disease status with plasma-based functional genomics.

Levy H, Jia S, Pan A, Zhang X, Kaldunski M, Nugent ML, Reske M, Feliciano RA, Quintero D, Renda MM, Woods KJ, Murkowski K, Johnson K, Verbsky J, Dasu T, Ideozu JE, McColley S, Quasney MW, Dahmer MK, Avner E, Farrell PM, Cannon CL, Jacob H, Simpson PM, Hessner MJ.

Physiol Genomics. 2019 Jan 1;51(1):27-41. doi: 10.1152/physiolgenomics.00109.2018. Epub 2018 Dec 12.

PMID:
30540547
2.

A Serum-Induced Transcriptome and Serum Cytokine Signature Obtained at Diagnosis Correlates with the Development of Early Pancreatic Ductal Adenocarcinoma Metastasis.

Tsai S, McOlash L, Jia S, Zhang J, Simpson P, Kaldunski ML, Aldakkak M, Grewal J, Palen K, Dwinell MB, Johnson BD, Mackinnon A, Hessner MJ, Gershan JA.

Cancer Epidemiol Biomarkers Prev. 2019 Apr;28(4):680-689. doi: 10.1158/1055-9965.EPI-18-0813. Epub 2018 Dec 7.

PMID:
30530849
3.

Innate immune activity as a predictor of persistent insulin secretion and association with responsiveness to CTLA4-Ig treatment in recent-onset type 1 diabetes.

Cabrera SM, Engle S, Kaldunski M, Jia S, Geoffrey R, Simpson P, Szabo A, Speake C, Greenbaum CJ; Type 1 Diabetes TrialNet CTLA4-Ig (Abatacept) Study Group, Chen YG, Hessner MJ.

Diabetologia. 2018 Nov;61(11):2356-2370. doi: 10.1007/s00125-018-4708-x. Epub 2018 Aug 30.

4.

Modulation of the diet and gastrointestinal microbiota normalizes systemic inflammation and β-cell chemokine expression associated with autoimmune diabetes susceptibility.

Henschel AM, Cabrera SM, Kaldunski ML, Jia S, Geoffrey R, Roethle MF, Lam V, Chen YG, Wang X, Salzman NH, Hessner MJ.

PLoS One. 2018 Jan 2;13(1):e0190351. doi: 10.1371/journal.pone.0190351. eCollection 2018.

5.

Interleukin-1 antagonism moderates the inflammatory state associated with Type 1 diabetes during clinical trials conducted at disease onset.

Cabrera SM, Wang X, Chen YG, Jia S, Kaldunski ML, Greenbaum CJ; Type 1 Diabetes TrialNet Canakinumab Study Group, Mandrup-Poulsen T; AIDA Study Group, Hessner MJ.

Eur J Immunol. 2016 Apr;46(4):1030-46. doi: 10.1002/eji.201546005. Epub 2016 Jan 21.

6.

Intermittent neonatal hypoxia elicits the upregulation of inflammatory-related genes in adult male rats through long-lasting programming effects.

Gehrand AL, Kaldunski ML, Bruder ED, Jia S, Hessner MJ, Raff H.

Physiol Rep. 2015 Dec;3(12). pii: e12646. doi: 10.14814/phy2.12646.

7.

Plasma-induced signatures reveal an extracellular milieu possessing an immunoregulatory bias in treatment-naive paediatric inflammatory bowel disease.

Gurram B, Salzman NH, Kaldunski ML, Jia S, Li BU, Stephens M, Sood MR, Hessner MJ.

Clin Exp Immunol. 2016 Apr;184(1):36-49. doi: 10.1111/cei.12753. Epub 2016 Jan 29.

8.

Identification of a novel gene for diabetic traits in rats, mice, and humans.

Tsaih SW, Holl K, Jia S, Kaldunski M, Tschannen M, He H, Andrae JW, Li SH, Stoddard A, Wiederhold A, Parrington J, Ruas da Silva M, Galione A, Meigs J; Meta-Analyses of Glucose and Insulin-Related Traits Consortium (MAGIC) Investigators, Hoffmann RG, Simpson P, Jacob H, Hessner M, Solberg Woods LC.

Genetics. 2014 Sep;198(1):17-29. doi: 10.1534/genetics.114.162982.

9.

Molecular signatures differentiate immune states in type 1 diabetic families.

Chen YG, Cabrera SM, Jia S, Kaldunski ML, Kramer J, Cheong S, Geoffrey R, Roethle MF, Woodliff JE, Greenbaum CJ, Wang X, Hessner MJ.

Diabetes. 2014 Nov;63(11):3960-73. doi: 10.2337/db14-0214. Epub 2014 Apr 23.

10.

Temporal induction of immunoregulatory processes coincides with age-dependent resistance to viral-induced type 1 diabetes.

Chen YG, Mordes JP, Blankenhorn EP, Kashmiri H, Kaldunski ML, Jia S, Geoffrey R, Wang X, Hessner MJ.

Genes Immun. 2013 Sep;14(6):387-400. doi: 10.1038/gene.2013.31. Epub 2013 Jun 6.

11.

Biobreeding rat islets exhibit reduced antioxidative defense and N-acetyl cysteine treatment delays type 1 diabetes.

Bogdani M, Henschel AM, Kansra S, Fuller JM, Geoffrey R, Jia S, Kaldunski ML, Pavletich S, Prosser S, Chen YG, Lernmark A, Hessner MJ.

J Endocrinol. 2013 Jan 18;216(2):111-23. doi: 10.1530/JOE-12-0385. Print 2013 Feb.

12.

Transcriptional signatures as a disease-specific and predictive inflammatory biomarker for type 1 diabetes.

Levy H, Wang X, Kaldunski M, Jia S, Kramer J, Pavletich SJ, Reske M, Gessel T, Yassai M, Quasney MW, Dahmer MK, Gorski J, Hessner MJ.

Genes Immun. 2012 Dec;13(8):593-604. doi: 10.1038/gene.2012.41. Epub 2012 Sep 13.

13.

Non-replication study of a genome-wide association study for hypertension and blood pressure in African Americans.

Kidambi S, Ghosh S, Kotchen JM, Grim CE, Krishnaswami S, Kaldunski ML, Cowley AW Jr, Patel SB, Kotchen TA.

BMC Med Genet. 2012 Apr 11;13:27. doi: 10.1186/1471-2350-13-27.

14.

Use of transcriptional signatures induced in lymphoid and myeloid cell lines as an inflammatory biomarker in Type 1 diabetes.

Jia S, Kaldunski M, Jailwala P, Geoffrey R, Kramer J, Wang X, Hessner MJ.

Physiol Genomics. 2011 Jun 15;43(11):697-709. doi: 10.1152/physiolgenomics.00235.2010. Epub 2011 Mar 15.

15.

Identification of a serum-induced transcriptional signature associated with type 1 diabetes in the BioBreeding rat.

Kaldunski M, Jia S, Geoffrey R, Basken J, Prosser S, Kansra S, Mordes JP, Lernmark A, Wang X, Hessner MJ.

Diabetes. 2010 Oct;59(10):2375-85. doi: 10.2337/db10-0372. Epub 2010 Aug 3.

16.

Phosducin influences sympathetic activity and prevents stress-induced hypertension in humans and mice.

Beetz N, Harrison MD, Brede M, Zong X, Urbanski MJ, Sietmann A, Kaufling J, Lorkowski S, Barrot M, Seeliger MW, Vieira-Coelho MA, Hamet P, Gaudet D, Seda O, Tremblay J, Kotchen TA, Kaldunski M, Nüsing R, Szabo B, Jacob HJ, Cowley AW Jr, Biel M, Stoll M, Lohse MJ, Broeckel U, Hein L.

J Clin Invest. 2009 Dec;119(12):3597-3612. doi: 10.1172/JCI38433. Erratum in: J Clin Invest. 2011 Jan 4;121(1):454. Lorkowski, Stefan [added].

17.

Molecular networks in Dahl salt-sensitive hypertension based on transcriptome analysis of a panel of consomic rats.

Liang M, Lee NH, Wang H, Greene AS, Kwitek AE, Kaldunski ML, Luu TV, Frank BC, Bugenhagen S, Jacob HJ, Cowley AW Jr.

Physiol Genomics. 2008 Jun 12;34(1):54-64. doi: 10.1152/physiolgenomics.00031.2008. Epub 2008 Apr 22.

PMID:
18430809
18.

High perfusion pressure accelerates renal injury in salt-sensitive hypertension.

Mori T, Polichnowski A, Glocka P, Kaldunski M, Ohsaki Y, Liang M, Cowley AW Jr.

J Am Soc Nephrol. 2008 Aug;19(8):1472-82. doi: 10.1681/ASN.2007121271. Epub 2008 Apr 16.

19.

Multiple blood pressure loci on rat chromosome 13 attenuate development of hypertension in the Dahl S hypertensive rat.

Moreno C, Kaldunski ML, Wang T, Roman RJ, Greene AS, Lazar J, Jacob HJ, Cowley AW Jr.

Physiol Genomics. 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. Erratum in: Physiol Genomics. 2009 Apr;37(2):147.

PMID:
17566075
20.

Efficient transgenic rat production by a lentiviral vector.

Michalkiewicz M, Michalkiewicz T, Geurts AM, Roman RJ, Slocum GR, Singer O, Weihrauch D, Greene AS, Kaldunski M, Verma IM, Jacob HJ, Cowley AW Jr.

Am J Physiol Heart Circ Physiol. 2007 Jul;293(1):H881-94. Epub 2007 Feb 23.

21.

Effect of sodium delivery on superoxide and nitric oxide in the medullary thick ascending limb.

Abe M, O'Connor P, Kaldunski M, Liang M, Roman RJ, Cowley AW Jr.

Am J Physiol Renal Physiol. 2006 Aug;291(2):F350-7. Epub 2006 Apr 4.

22.

Genome-wide scan for linkage to obesity-associated hypertension in French Canadians.

Pausova Z, Gaudet D, Gossard F, Bernard M, Kaldunski ML, Jomphe M, Tremblay J, Hudson TJ, Bouchard G, Kotchen TA, Cowley AW, Hamet P.

Hypertension. 2005 Dec;46(6):1280-5. Epub 2005 Oct 10.

PMID:
16216983
23.

Quantitative founder-effect analysis of French Canadian families identifies specific loci contributing to metabolic phenotypes of hypertension.

Hamet P, Merlo E, Seda O, Broeckel U, Tremblay J, Kaldunski M, Gaudet D, Bouchard G, Deslauriers B, Gagnon F, Antoniol G, Pausová Z, Labuda M, Jomphe M, Gossard F, Tremblay G, Kirova R, Tonellato P, Orlov SN, Pintos J, Platko J, Hudson TJ, Rioux JD, Kotchen TA, Cowley AW Jr.

Am J Hum Genet. 2005 May;76(5):815-32. Epub 2005 Mar 30.

24.

Hyperaldosteronism and hypertension: ethnic differences.

Grim CE, Cowley AW Jr, Hamet P, Gaudet D, Kaldunski ML, Kotchen JM, Krishnaswami S, Pausova Z, Roman R, Tremblay J, Kotchen TA.

Hypertension. 2005 Apr;45(4):766-72. Epub 2005 Feb 7.

PMID:
15699471
25.

Influence of diet and genetics on hypertension and renal disease in Dahl salt-sensitive rats.

Mattson DL, Kunert MP, Kaldunski ML, Greene AS, Roman RJ, Jacob HJ, Cowley AW Jr.

Physiol Genomics. 2004 Jan 15;16(2):194-203.

PMID:
14600213
26.

Genomic map of cardiovascular phenotypes of hypertension in female Dahl S rats.

Moreno C, Dumas P, Kaldunski ML, Tonellato PJ, Greene AS, Roman RJ, Cheng Q, Wang Z, Jacob HJ, Cowley AW Jr.

Physiol Genomics. 2003 Nov 11;15(3):243-57.

PMID:
14532335
27.

Gender-specific correlates of leptin with hypertension-related phenotypes in African Americans.

El-Gharbawy AH, Kotchen JM, Grim CE, Kaldunski M, Hoffmann RG, Pausova Z, Hamet P, Kotchen TA.

Am J Hypertens. 2002 Nov;15(11):989-93.

PMID:
12441220
28.

Identification of hypertension-related QTLs in African American sib pairs.

Kotchen TA, Broeckel U, Grim CE, Hamet P, Jacob H, Kaldunski ML, Kotchen JM, Schork NJ, Tonellato PJ, Cowley AW Jr.

Hypertension. 2002 Nov;40(5):634-9.

PMID:
12411455
29.

A genomic-systems biology map for cardiovascular function.

Stoll M, Cowley AW Jr, Tonellato PJ, Greene AS, Kaldunski ML, Roman RJ, Dumas P, Schork NJ, Wang Z, Jacob HJ.

Science. 2001 Nov 23;294(5547):1723-6.

30.

Predictors of target organ damage in hypertensive blacks and whites.

El-Gharbawy AH, Kotchen JM, Grim CE, Kaldunski M, Hoffmann RG, Pausova Z, Gaudet D, Gossard F, Hamet P, Kotchen TA.

Hypertension. 2001 Oct;38(4):761-6.

PMID:
11641283
31.

Arterial pressure, left ventricular mass, and aldosterone in essential hypertension.

El-Gharbawy AH, Nadig VS, Kotchen JM, Grim CE, Sagar KB, Kaldunski M, Hamet P, Pausova Z, Gaudet D, Gossard F, Kotchen TA.

Hypertension. 2001 Mar;37(3):845-50.

PMID:
11244006
32.

Brown Norway chromosome 13 confers protection from high salt to consomic Dahl S rat.

Cowley AW Jr, Roman RJ, Kaldunski ML, Dumas P, Dickhout JG, Greene AS, Jacob HJ.

Hypertension. 2001 Feb;37(2 Pt 2):456-61.

PMID:
11230318
33.

Genetically defined risk of salt sensitivity in an intercross of Brown Norway and Dahl S rats.

Cowley AW Jr, Stoll M, Greene AS, Kaldunski ML, Roman RJ, Tonellato PJ, Schork NJ, Dumas P, Jacob HJ.

Physiol Genomics. 2000 Apr 27;2(3):107-15.

PMID:
11015589
34.

Genetic determinants of hypertension: identification of candidate phenotypes.

Kotchen TA, Kotchen JM, Grim CE, George V, Kaldunski ML, Cowley AW, Hamet P, Chelius TH.

Hypertension. 2000 Jul;36(1):7-13.

PMID:
10904005
35.

Glomerular hyperfiltration in hypertensive African Americans.

Kotchen TA, Piering AW, Cowley AW, Grim CE, Gaudet D, Hamet P, Kaldunski ML, Kotchen JM, Roman RJ.

Hypertension. 2000 Mar;35(3):822-6.

PMID:
10720601
36.

Coexistence of two types of Ca(2+)-activated K+ channels in rat renal arterioles.

Gebremedhin D, Kaldunski M, Jacobs ER, Harder DR, Roman RJ.

Am J Physiol. 1996 Jan;270(1 Pt 2):F69-81.

PMID:
8769824
37.

Inhibition of renal vascular 20-HETE production impairs autoregulation of renal blood flow.

Zou AP, Imig JD, Kaldunski M, Ortiz de Montellano PR, Sui Z, Roman RJ.

Am J Physiol. 1994 Feb;266(2 Pt 2):F275-82.

PMID:
8141328
38.

Pressure natriuresis and cortical and papillary blood flow in inbred Dahl rats.

Roman RJ, Kaldunski M.

Am J Physiol. 1991 Sep;261(3 Pt 2):R595-602.

PMID:
1887948
39.

Enhanced chloride reabsorption in the loop of Henle in Dahl salt-sensitive rats.

Roman RJ, Kaldunski ML.

Hypertension. 1991 Jun;17(6 Pt 2):1018-24.

PMID:
2045146
40.

Influence of kinins and angiotensin II on the regulation of papillary blood flow.

Roman RJ, Kaldunski ML, Scicli AG, Carretero OA.

Am J Physiol. 1988 Oct;255(4 Pt 2):F690-8.

PMID:
2845811
41.

Influence of eicosanoids on renal function of DOCA-salt hypertensive rats.

Roman RJ, Kaldunski ML, Mattson DL, Mistry M, Nasjletti A.

Hypertension. 1988 Sep;12(3):287-94.

PMID:
3169943
42.

Renal cortical and papillary blood flow in spontaneously hypertensive rats.

Roman RJ, Kaldunski ML.

Hypertension. 1988 Jun;11(6 Pt 2):657-63.

PMID:
3391676

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