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Items: 1 to 50 of 90

1.
2.

Histone H3 peptides incorporating modified lysine residues as lysine-specific demethylase 1 inhibitors.

Kakizawa T, Ota Y, Itoh Y, Suzuki T.

Bioorg Med Chem Lett. 2018 Jan 15;28(2):167-169. doi: 10.1016/j.bmcl.2017.11.035. Epub 2017 Nov 23.

PMID:
29198865
3.

Potent mechanism-based sirtuin-2-selective inhibition by an in situ-generated occupant of the substrate-binding site, "selectivity pocket" and NAD+-binding site.

Mellini P, Itoh Y, Tsumoto H, Li Y, Suzuki M, Tokuda N, Kakizawa T, Miura Y, Takeuchi J, Lahtela-Kakkonen M, Suzuki T.

Chem Sci. 2017 Sep 1;8(9):6400-6408. doi: 10.1039/c7sc02738a. Epub 2017 Jul 21.

4.

Crystal structure of [1,2-bis-(di-phenyl-phosphan-yl)benzene]-hepta-carbonyldi-μ-hydrido-(μ3-2,4,6-tri-methyl-phenyl-phosphin-idene)-triangulo-triruthenium.

Kakizawa T.

Acta Crystallogr E Crystallogr Commun. 2017 Jun 2;73(Pt 7):945-948. doi: 10.1107/S2056989017007770. eCollection 2017 Jul 1.

5.

Design, synthesis, and evaluation of Trolox-conjugated amyloid-β C-terminal peptides for therapeutic intervention in an in vitro model of Alzheimer's disease.

Arai T, Ohno A, Kazunori M, Kakizawa T, Kuwata H, Ozawa T, Shibanuma M, Hara S, Ishida S, Kurihara M, Miyata N, Nakagawa H, Fukuhara K.

Bioorg Med Chem. 2016 Sep 15;24(18):4138-4143. doi: 10.1016/j.bmc.2016.06.057. Epub 2016 Jun 30.

PMID:
27407032
6.

Evaluation of phenylcyclopropylamine compounds by enzymatic assay of lysine-specific demethylase 2 in the presence of NPAC peptide.

Kakizawa T, Mizukami T, Itoh Y, Hasegawa M, Sasaki R, Suzuki T.

Bioorg Med Chem Lett. 2016 Feb 15;26(4):1193-5. doi: 10.1016/j.bmcl.2016.01.036. Epub 2016 Jan 16.

PMID:
26794039
7.

Histone H3 peptide based LSD1-selective inhibitors.

Kakizawa T, Ota Y, Itoh Y, Tsumoto H, Suzuki T.

Bioorg Med Chem Lett. 2015 May 1;25(9):1925-8. doi: 10.1016/j.bmcl.2015.03.030. Epub 2015 Mar 20.

PMID:
25827526
8.

Efficacy of combination therapy with sitagliptin and low-dose glimepiride in Japanese patients with type 2 diabetes.

Ishii H, Ohkubo Y, Takei M, Nishio S, Yamazaki M, Kumagai M, Sato Y, Suzuki S, Aoki Y, Miyamoto T, Kakizawa T, Sakuma T, Komatsu M.

J Clin Med Res. 2014 Apr;6(2):127-32. doi: 10.14740/jocmr1701w. Epub 2014 Feb 6.

9.

Genome-wide association study of sensory disturbances in the inferior alveolar nerve after bilateral sagittal split ramus osteotomy.

Kobayashi D, Nishizawa D, Takasaki Y, Kasai S, Kakizawa T, Ikeda K, Fukuda K.

Mol Pain. 2013 Jul 8;9:34. doi: 10.1186/1744-8069-9-34.

10.

Lysine-specific demethylase 1-selective inactivators: protein-targeted drug delivery mechanism.

Ogasawara D, Itoh Y, Tsumoto H, Kakizawa T, Mino K, Fukuhara K, Nakagawa H, Hasegawa M, Sasaki R, Mizukami T, Miyata N, Suzuki T.

Angew Chem Int Ed Engl. 2013 Aug 12;52(33):8620-4. doi: 10.1002/anie.201303999. Epub 2013 Jul 3. No abstract available.

PMID:
23824985
11.

Octa-carbonyldi-μ(2)-hydrido-[μ(3)-(1,3,5-trimethyl-phen-yl)phosphinidene](tri-phenyl-phosphane)-triangulo-triruthenium.

Kakizawa T.

Acta Crystallogr Sect E Struct Rep Online. 2012 Oct 1;68(Pt 10):m1293. doi: 10.1107/S1600536812039499. Epub 2012 Sep 22.

12.

Intravenous sedation and hemodynamic changes during dental implant surgery.

Taguchi T, Fukuda K, Sekine H, Kakizawa T.

Int J Oral Maxillofac Implants. 2011 Nov-Dec;26(6):1303-8.

PMID:
22167437
13.

Self-assembly pathways of E22Δ-type amyloid β peptide mutants generated from non-aggregative O-acyl isopeptide precursors.

Sohma Y, Wang H, Taniguchi A, Hirayama Y, Kakizawa T, Yamasaki M, Mukai H, Kiso Y.

Bioorg Med Chem. 2011 Jun 15;19(12):3787-92. doi: 10.1016/j.bmc.2011.04.056. Epub 2011 May 6.

PMID:
21612934
14.

Development of [Ile⁴⁰]HTLV-I protease inhibition assay using novel fluorogenic and chromogenic substrate.

Kumada HO, Nguyen JT, Kakizawa T, Hidaka K, Kimura T, Hayashi Y, Kiso Y.

J Pept Sci. 2011 Aug;17(8):569-75. doi: 10.1002/psc.1375. Epub 2011 May 13.

PMID:
21574213
15.

Evaluation of superior BACE1 cleavage sequences containing unnatural amino acids.

Kakizawa T, Sanjoh A, Kobayashi A, Hattori Y, Teruya K, Akaji K.

Bioorg Med Chem. 2011 May 1;19(9):2785-9. doi: 10.1016/j.bmc.2011.03.056. Epub 2011 Mar 29.

PMID:
21489805
16.

Automatic segmentation of teeth from dentomaxillofacial 3D-CT images.

Aizawa M, Nishikawa K, Sasaki K, Kobayashi N, Yama M, Kakizawa T, Sano T, Murakami S.

Nihon Hoshasen Gijutsu Gakkai Zasshi. 2010 Apr 20;66(4):343-52.

17.

Tetrapeptides, as small-sized peptidic inhibitors; synthesis and their inhibitory activity against BACE1.

Kakizawa T, Hidaka K, Hamada D, Yamaguchi R, Uemura T, Kitamura H, Tagad HD, Hamada T, Ziora Z, Hamada Y, Kimura T, Kiso Y.

J Pept Sci. 2010 Jun;16(6):257-62. doi: 10.1002/psc.1238.

PMID:
20474036
18.

Antimicrobial activity of super-oxidised water against oral microorganisms.

Yamada K, Yama M, Takaku Y, Kakizawa T, Kimizuka R, Okuda K, Kato T.

Arch Oral Biol. 2010 Jun;55(6):397-400. doi: 10.1016/j.archoralbio.2010.03.002. Epub 2010 Apr 9.

PMID:
20381790
19.

Dehydrocoupling reactions of borane-secondary and -primary amine adducts catalyzed by group-6 carbonyl complexes: formation of aminoboranes and borazines.

Kawano Y, Uruichi M, Shimoi M, Taki S, Kawaguchi T, Kakizawa T, Ogino H.

J Am Chem Soc. 2009 Oct 21;131(41):14946-57. doi: 10.1021/ja904918u.

PMID:
19772343
20.

Systemic Inflammatory Response Syndrome and postoperative complications after orthognathic surgery.

Kasahara K, Yajima Y, Ikeda C, Kamiyama I, Takaki T, Kakizawa T, Shibahara T.

Bull Tokyo Dent Coll. 2009 Feb;50(1):41-50.

21.

Synthesis of amyloid beta peptide 1-42 (E22Delta) click peptide: pH-triggered in situ production of its native form.

Wang H, Kakizawa T, Taniguchi A, Mizuguchi T, Kimura T, Kiso Y.

Bioorg Med Chem. 2009 Jul 15;17(14):4881-7. doi: 10.1016/j.bmc.2009.06.017. Epub 2009 Jun 16.

PMID:
19564119
22.

Patient in whom surgery was selected to improve mandible position after changing doctors.

Miyazaki H, Sueishi K, Takano M, Kakizawa T.

Bull Tokyo Dent Coll. 2008 Nov;49(4):191-8.

23.

Inhibitory effect of a dimerization-arm-mimetic peptide on EGF receptor activation.

Mizuguchi T, Uchimura H, Kakizawa T, Kimura T, Yokoyama S, Kiso Y, Saito K.

Bioorg Med Chem Lett. 2009 Jun 15;19(12):3279-82. doi: 10.1016/j.bmcl.2009.04.080. Epub 2009 Apr 23.

PMID:
19419869
24.

Biphasic function of focal adhesion kinase in endothelial tube formation induced by fibril-forming collagens.

Nakamura J, Shigematsu S, Yamauchi K, Takeda T, Yamazaki M, Kakizawa T, Hashizume K.

Biochem Biophys Res Commun. 2008 Oct 3;374(4):699-703. doi: 10.1016/j.bbrc.2008.07.123. Epub 2008 Aug 3.

PMID:
18680726
25.

Risk factors for falls among blind elderly in a nursing home for the blind.

Nakamura T, Kagawa K, Kakizawa T, Seo M, Iketani N, Ono H, Tanimura Y.

Arch Gerontol Geriatr. 1998 Jul-Aug;27(1):9-17.

PMID:
18653146
26.

Switching from the unfolded to the folded state of the helix-loop-helix domain of the Id proteins based on the O-acyl isopeptide method.

Kiewitz SD, Kakizawa T, Kiso Y, Cabrele C.

J Pept Sci. 2008 Nov;14(11):1209-15. doi: 10.1002/psc.1059.

PMID:
18636401
27.

Dental implant treatment with different techniques for sinus floor elevation--a case report.

Sekine H, Taguchi T, Seta S, Takano M, Takeda T, Kakizawa T.

Bull Tokyo Dent Coll. 2007 May;48(2):87-91.

28.

Fmoc-based solid phase chemical synthesis of 71-meric neuregulin 1-beta1, an epidermal growth factor-like domain.

Kakizawa T, Koide-Yoshida S, Kimura T, Uchimura H, Hayashi Y, Saito K, Kiso Y.

J Pept Sci. 2008 Mar;14(3):261-6.

PMID:
17880034
29.

OTX5 regulates pineal expression of the zebrafish REV-ERB alpha through a new DNA binding site.

Nishio S, Kakizawa T, Chatelain G, Triqueneaux G, Brunet F, Rambaud J, Lamonerie T, Laudet V.

Mol Endocrinol. 2008 Jan;22(1):23-32. Epub 2007 Sep 13.

31.

Two differentially active alternative promoters control the expression of the zebrafish orphan nuclear receptor gene Rev-erbalpha.

Kakizawa T, Nishio S, Triqueneaux G, Bertrand S, Rambaud J, Laudet V.

J Mol Endocrinol. 2007 May;38(5):555-68.

PMID:
17496157
32.

Administration of recombinant human growth hormone normalizes GH-IGF1 axis and improves malnutrition-related disorders in patients with anorexia nervosa.

Hashizume K, Suzuki S, Komatsu A, Hiramatsu K, Mori J, Yamazaki M, Takeda T, Kakizawa T, Miyamoto T, Koizumi Y, Ichikawa K.

Endocr J. 2007 Apr;54(2):319-27. Epub 2007 Mar 6. Retraction in: Endocr J. 2009;56(5):726.

33.

Insulin Autoimmune Syndrome possibly caused by alpha lipoic acid.

Takeuchi Y, Miyamoto T, Kakizawa T, Shigematsu S, Hashizume K.

Intern Med. 2007;46(5):237-9. Epub 2007 Mar 1.

34.

Synergistic regulation of the mouse orphan nuclear receptor SHP gene promoter by CLOCK-BMAL1 and LRH-1.

Oiwa A, Kakizawa T, Miyamoto T, Yamashita K, Jiang W, Takeda T, Suzuki S, Hashizume K.

Biochem Biophys Res Commun. 2007 Feb 23;353(4):895-901. Epub 2006 Dec 26.

PMID:
17204240
35.

Inhibition of LXRalpha signaling by vitamin D receptor: possible role of VDR in bile acid synthesis.

Jiang W, Miyamoto T, Kakizawa T, Nishio SI, Oiwa A, Takeda T, Suzuki S, Hashizume K.

Biochem Biophys Res Commun. 2006 Dec 8;351(1):176-84. Epub 2006 Oct 19.

PMID:
17054913
36.

Adenomatoid odontogenic tumor arising from the mandibular molar region: a case report and review of the literature.

Sato D, Matsuzaka K, Yama M, Kakizawa T, Inoue T.

Bull Tokyo Dent Coll. 2004 Nov;45(4):223-7. Review.

37.

The orphan receptor Rev-erbalpha gene is a target of the circadian clock pacemaker.

Triqueneaux G, Thenot S, Kakizawa T, Antoch MP, Safi R, Takahashi JS, Delaunay F, Laudet V.

J Mol Endocrinol. 2004 Dec;33(3):585-608.

38.

Expression of thyroid hormone receptor alpha in 3T3-L1 adipocytes; triiodothyronine increases the expression of lipogenic enzyme and triglyceride accumulation.

Jiang W, Miyamoto T, Kakizawa T, Sakuma T, Nishio S, Takeda T, Suzuki S, Hashizume K.

J Endocrinol. 2004 Aug;182(2):295-302.

PMID:
15283690
39.

Current usage of three-dimensional computed tomography angiography for the diagnosis and treatment of ruptured cerebral aneurysms.

Amagasaki K, Takeuchi N, Sato T, Kakizawa T, Shimizu T.

J Clin Neurosci. 2004 Jun;11(5):481-5.

PMID:
15177388
40.

Inhibition of peroxisome proliferator-activated receptor alpha signaling by vitamin D receptor.

Sakuma T, Miyamoto T, Jiang W, Kakizawa T, Nishio SI, Suzuki S, Takeda T, Oiwa A, Hashizume K.

Biochem Biophys Res Commun. 2003 Dec 12;312(2):513-9.

PMID:
14637167
41.

The days and nights of cancer cells.

Canaple L, Kakizawa T, Laudet V.

Cancer Res. 2003 Nov 15;63(22):7545-52. Review.

42.

Tumor-specific gene therapy for undifferentiated thyroid carcinoma utilizing the telomerase reverse transcriptase promoter.

Takeda T, Inaba H, Yamazaki M, Kyo S, Miyamoto T, Suzuki S, Ehara T, Kakizawa T, Hara M, DeGroot LJ, Hashizume K.

J Clin Endocrinol Metab. 2003 Aug;88(8):3531-8.

PMID:
12915632
43.

Oral cancer research with an emphasis on genomic analysis.

Shibahara T, Noma H, Kakizawa T, Ohtsuru H, Fukutake K, Uchida I.

Bull Tokyo Dent Coll. 2002 Nov;43(4):209-22. Review.

44.

Oncocytic tumor in myoepithelioma arising from the grossopalatine gland.

Matsuzaka K, Murakami S, Shimono M, Kakizawa T, Inoue T.

Oral Oncol. 2003 Apr;39(3):306-8.

PMID:
12618205
45.

Hypoplasia of primary and permanent teeth following osteitis and the implications of delayed diagnosis of a neonatal maxillary primary molar.

Kimoto S, Suga H, Yamaguchi M, Uchimura N, Ikeda M, Kakizawa T.

Int J Paediatr Dent. 2003 Jan;13(1):35-40.

PMID:
12542622
46.

Late recurrence of subarachnoid hemorrhage due to regrowth of aneurysm after neck clipping surgery.

Amagasaki K, Higa T, Takeuchi N, Kakizawa T, Shimizu T.

Neurol Med Chir (Tokyo). 2002 Nov;42(11):496-500.

47.

A tandemly repeated thyroglobulin core promoter has potential to enhance efficacy for tissue-specific gene therapy for thyroid carcinomas.

Takeda T, Yamazaki M, Minemura K, Imai Y, Inaba H, Suzuki S, Miyamoto T, Ichikawa K, Kakizawa T, Mori J, DeGroot LJ, Hashizume K.

Cancer Gene Ther. 2002 Oct;9(10):864-74.

48.

Bilateral cortical blindness associated with cerebral angiitis.

Amagasaki K, Takeuchi N, Kakizawa T, Shimizu T.

Acta Neurochir (Wien). 2002 Jul;144(7):749. No abstract available.

PMID:
12181712
50.

Clinicostatistical study of ameloblastoma treatment.

Hatada K, Noma H, Katakura A, Yama M, Takano M, Ide Y, Takaki T, Yajima Y, Shibahara T, Kakizawa T, Tonogi M, Yamane G.

Bull Tokyo Dent Coll. 2001 May;42(2):87-95.

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