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Items: 20

1.

Safety Considerations in the Development of Hippo Pathway Inhibitors in Cancers.

Kakiuchi-Kiyota S, Schutten MM, Zhong Y, Crawford JJ, Dey A.

Front Cell Dev Biol. 2019 Aug 14;7:156. doi: 10.3389/fcell.2019.00156. eCollection 2019. Review.

2.

Physiology of the Neonatal Gastrointestinal System Relevant to the Disposition of Orally Administered Medications.

Neal-Kluever A, Fisher J, Grylack L, Kakiuchi-Kiyota S, Halpern W.

Drug Metab Dispos. 2019 Mar;47(3):296-313. doi: 10.1124/dmd.118.084418. Epub 2018 Dec 19.

PMID:
30567878
3.

Computational analysis of kinase inhibitor selectivity using structural knowledge.

Lo YC, Liu T, Morrissey KM, Kakiuchi-Kiyota S, Johnson AR, Broccatelli F, Zhong Y, Joshi A, Altman RB.

Bioinformatics. 2019 Jan 15;35(2):235-242. doi: 10.1093/bioinformatics/bty582.

PMID:
29985971
4.

Development of a Method for Profiling Protein Interactions with LNA-Modified Antisense Oligonucleotides Using Protein Microarrays.

Kakiuchi-Kiyota S, Whiteley LO, Ryan AM, Mathialagan N.

Nucleic Acid Ther. 2016 Apr;26(2):93-101. doi: 10.1089/nat.2015.0576. Epub 2015 Dec 7.

PMID:
26643897
5.

Comparison of hepatic transcription profiles of locked ribonucleic acid antisense oligonucleotides: evidence of distinct pathways contributing to non-target mediated toxicity in mice.

Kakiuchi-Kiyota S, Koza-Taylor PH, Mantena SR, Nelms LF, Enayetallah AE, Hollingshead BD, Burdick AD, Reed LA, Warneke JA, Whiteley LO, Ryan AM, Mathialagan N.

Toxicol Sci. 2014 Mar;138(1):234-48. doi: 10.1093/toxsci/kft278. Epub 2013 Dec 11.

PMID:
24336348
6.

Pathogenesis of human hemangiosarcomas and hemangiomas.

Liu L, Kakiuchi-Kiyota S, Arnold LL, Johansson SL, Wert D, Cohen SM.

Hum Pathol. 2013 Oct;44(10):2302-11. doi: 10.1016/j.humpath.2013.05.012.

PMID:
24054722
7.

Cytotoxicity and gene expression changes induced by inorganic and organic trivalent arsenicals in human cells.

Dodmane PR, Arnold LL, Kakiuchi-Kiyota S, Qiu F, Liu X, Rennard SI, Cohen SM.

Toxicology. 2013 Oct 4;312:18-29. doi: 10.1016/j.tox.2013.07.008. Epub 2013 Jul 19.

PMID:
23876855
8.

Expression of proto-oncogene cFMS protein in lung, breast, and ovarian cancers.

Kakiuchi-Kiyota S, Lappin PB, Heintz C, Brown PW, Pinho FO, Ryan AM, Mathialagan N.

Appl Immunohistochem Mol Morphol. 2014 Mar;22(3):188-99. doi: 10.1097/PAI.0b013e31828e7104.

PMID:
23702648
9.

Time course of urothelial changes in rats and mice orally administered arsenite.

Arnold LL, Suzuki S, Yokohira M, Kakiuchi-Kiyota S, Pennington KL, Cohen SM.

Toxicol Pathol. 2014 Jul;42(5):855-62. doi: 10.1177/0192623313489778. Epub 2013 May 20.

PMID:
23690446
10.

Evaluation of expression profiles of hematopoietic stem cell, endothelial cell, and myeloid cell antigens in spontaneous and chemically induced hemangiosarcomas and hemangiomas in mice.

Kakiuchi-Kiyota S, Crabbs TA, Arnold LL, Pennington KL, Cook JC, Malarkey DE, Cohen SM.

Toxicol Pathol. 2013 Jul;41(5):709-21. doi: 10.1177/0192623312464309. Epub 2012 Nov 2.

PMID:
23125116
11.

Effects of co-administration of dietary sodium arsenate and 2,3-dimercaptopropane-1-sulfonic acid (DMPS) on the rat bladder epithelium.

Suzuki S, Arnold LL, Pennington KL, Kakiuchi-Kiyota S, Chen B, Lu X, Le XC, Cohen SM.

Toxicology. 2012 Sep 28;299(2-3):155-9. doi: 10.1016/j.tox.2012.05.019. Epub 2012 Jun 1.

PMID:
22664484
12.

Evaluation of direct and indirect effects of the PPARĪ³ agonist troglitazone on mouse endothelial cell proliferation.

Kakiuchi-Kiyota S, Arnold LL, Yokohira M, Koza-Taylor P, Suzuki S, Varney M, Pennington KL, Cohen SM.

Toxicol Pathol. 2011 Dec;39(7):1032-45. doi: 10.1177/0192623311422080. Epub 2011 Sep 21.

PMID:
21937740
13.

Evaluation of PPARĪ³ agonists on rodent endothelial cell proliferation.

Kakiuchi-Kiyota S, Arnold LL, Yokohira M, Suzuki S, Pennington KL, Cohen SM.

Toxicology. 2011 Sep 5;287(1-3):91-8. doi: 10.1016/j.tox.2011.05.019. Epub 2011 Jun 12.

PMID:
21684317
14.

Effect of sodium arsenite dose administered in the drinking water on the urinary bladder epithelium of female arsenic (+3 oxidation state) methyltransferase knockout mice.

Yokohira M, Arnold LL, Pennington KL, Suzuki S, Kakiuchi-Kiyota S, Herbin-Davis K, Thomas DJ, Cohen SM.

Toxicol Sci. 2011 Jun;121(2):257-66. doi: 10.1093/toxsci/kfr051. Epub 2011 Mar 7.

PMID:
21385732
15.

The effects of oral treatment with transfluthrin on the urothelium of rats and its metabolite, tetrafluorobenzoic acid on urothelial cells in vitro.

Yokohira M, Arnold LL, Lautraite S, Sheets L, Wason S, Stahl B, Eigenberg D, Pennington KL, Kakiuchi-Kiyota S, Cohen SM.

Food Chem Toxicol. 2011 Jun;49(6):1215-23. doi: 10.1016/j.fct.2011.02.022. Epub 2011 Mar 4.

PMID:
21377505
16.

Severe systemic toxicity and urinary bladder cytotoxicity and regenerative hyperplasia induced by arsenite in arsenic (+3 oxidation state) methyltransferase knockout mice. A preliminary report.

Yokohira M, Arnold LL, Pennington KL, Suzuki S, Kakiuchi-Kiyota S, Herbin-Davis K, Thomas DJ, Cohen SM.

Toxicol Appl Pharmacol. 2010 Jul;246(1-2):1-7. doi: 10.1016/j.taap.2010.04.013. Epub 2010 Apr 25.

PMID:
20423714
17.

Effects of pioglitazone, a peroxisome proliferator-activated receptor gamma agonist, on the urine and urothelium of the rat.

Suzuki S, Arnold LL, Pennington KL, Kakiuchi-Kiyota S, Wei M, Wanibuchi H, Cohen SM.

Toxicol Sci. 2010 Feb;113(2):349-57. doi: 10.1093/toxsci/kfp256. Epub 2009 Oct 25.

PMID:
19858066
18.

Effects of co-administration of dietary sodium arsenite and an NADPH oxidase inhibitor on the rat bladder epithelium.

Suzuki S, Arnold LL, Pennington KL, Kakiuchi-Kiyota S, Cohen SM.

Toxicology. 2009 Jun 30;261(1-2):41-6. doi: 10.1016/j.tox.2009.04.042. Epub 2009 May 3.

PMID:
19397947
19.

Effects of the PPARgamma agonist troglitazone on endothelial cells in vivo and in vitro: differences between human and mouse.

Kakiuchi-Kiyota S, Vetro JA, Suzuki S, Varney ML, Han HY, Nascimento M, Pennington KL, Arnold LL, Singh RK, Cohen SM.

Toxicol Appl Pharmacol. 2009 May 15;237(1):83-90. doi: 10.1016/j.taap.2009.02.028. Epub 2009 Mar 11. Erratum in: Toxicol Appl Pharmacol. 2011 Jun 15;253(3):290.

PMID:
19285096
20.

Inorganic arsenic-induced intramitochondrial granules in mouse urothelium.

Suzuki S, Arnold LL, Muirhead D, Lu X, Le XC, Bjork JA, Wallace KB, Ohnishi T, Kakiuchi-Kiyota S, Pennington KL, Cohen SM.

Toxicol Pathol. 2008 Dec;36(7):999-1005. doi: 10.1177/0192623308327408.

PMID:
19126794

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