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Items: 1 to 50 of 254

1.

Fetal malnutrition-induced catch up failure is caused by elevated levels of miR-322 in rats.

Nemoto T, Kakinuma Y.

Sci Rep. 2020 Jan 28;10(1):1339. doi: 10.1038/s41598-020-58392-x.

2.

Stress-induced microglial activation occurs through β-adrenergic receptor: noradrenaline as a key neurotransmitter in microglial activation.

Sugama S, Takenouchi T, Hashimoto M, Ohata H, Takenaka Y, Kakinuma Y.

J Neuroinflammation. 2019 Dec 17;16(1):266. doi: 10.1186/s12974-019-1632-z.

3.

A PQ-loop protein Ypq2 is involved in the exchange of arginine and histidine across the vacuolar membrane of Saccharomyces cerevisiae.

Kawano-Kawada M, Manabe K, Ichimura H, Kimura T, Harada Y, Ikeda K, Tanaka S, Kakinuma Y, Sekito T.

Sci Rep. 2019 Oct 21;9(1):15018. doi: 10.1038/s41598-019-51531-z.

4.

Octave-wide phase-matched four-wave mixing in dispersion-engineered crystalline microresonators.

Fujii S, Tanaka S, Fuchida M, Amano H, Hayama Y, Suzuki R, Kakinuma Y, Tanabe T.

Opt Lett. 2019 Jun 15;44(12):3146-3149. doi: 10.1364/OL.44.003146.

PMID:
31199402
5.

Potentiating a non-neuronal cardiac cholinergic system reinforces the functional integrity of the blood brain barrier associated with systemic anti-inflammatory responses.

Oikawa S, Kai Y, Mano A, Sugama S, Mizoguchi N, Tsuda M, Muramoto K, Kakinuma Y.

Brain Behav Immun. 2019 Oct;81:122-137. doi: 10.1016/j.bbi.2019.06.005. Epub 2019 Jun 6.

PMID:
31176726
6.
7.

The non-neuronal cholinergic system in the heart: A comprehensive review.

Saw EL, Kakinuma Y, Fronius M, Katare R.

J Mol Cell Cardiol. 2018 Dec;125:129-139. doi: 10.1016/j.yjmcc.2018.10.013. Epub 2018 Oct 19. Review.

PMID:
30343172
8.

Transport of Amino Acids across the Vacuolar Membrane of Yeast: Its Mechanism and Physiological Role.

Kawano-Kawada M, Kakinuma Y, Sekito T.

Biol Pharm Bull. 2018;41(10):1496-1501. doi: 10.1248/bpb.b18-00165. Review.

9.

Involvement of Noncoding RNAs in Stress-Related Neuropsychiatric Diseases Caused by DOHaD Theory : ncRNAs and DOHaD-Induced Neuropsychiatric Diseases.

Nemoto T, Kakinuma Y.

Adv Exp Med Biol. 2018;1012:49-59. doi: 10.1007/978-981-10-5526-3_6. Review.

PMID:
29956194
10.

Evaluation of Teneligliptin Effects on Transcriptional Activity of PPARγ in Cell-Based Assays.

Takenaka Y, Inoue I, Nakano T, Ikeda M, Kakinuma Y, Ikegami Y, Shimada A, Noda M.

J Nippon Med Sch. 2018;85(2):95-101. doi: 10.1272/jnms.2018_85-15.

11.

Quality-Quantity Control Culture Enhances Vasculogenesis and Wound Healing Efficacy of Human Diabetic Peripheral Blood CD34+ Cells.

Tanaka R, Masuda H, Fujimura S, Ito-Hirano R, Arita K, Kakinuma Y, Hagiwara H, Kado M, Hayashi A, Mita T, Ogawa T, Watada H, Mizuno H, Sawada N, Asahara T.

Stem Cells Transl Med. 2018 May;7(5):428-438. doi: 10.1002/sctm.17-0043. Epub 2018 Mar 24.

12.

Murine remote preconditioning increases glucose uptake and suppresses gluconeogenesis in hepatocytes via a brain-liver neurocircuit, leading to counteracting glucose intolerance.

Kurabayashi A, Tanaka C, Matsumoto W, Naganuma S, Furihata M, Inoue K, Kakinuma Y.

Diabetes Res Clin Pract. 2018 May;139:288-299. doi: 10.1016/j.diabres.2018.03.009. Epub 2018 Mar 9.

PMID:
29526685
13.

A study of the blood flow restriction pressure of a tourniquet system to facilitate development of a system that can prevent musculoskeletal complications.

Maeda H, Iwase H, Kanda A, Morohashi I, Kaneko K, Maeda M, Kakinuma Y, Takei Y, Amemiya S, Mitsui K.

Am J Disaster Med. 2017 Summer;12(3):139-145. doi: 10.5055/ajdm.2017.0267.

PMID:
29270956
14.

Possible Involvement of Liver Resident Macrophages (Kupffer Cells) in the Pathogenesis of Both Intrahepatic and Extrahepatic Inflammation.

Kakinuma Y, Kimura T, Watanabe Y.

Can J Gastroenterol Hepatol. 2017;2017:2896809. doi: 10.1155/2017/2896809. Epub 2017 Jul 19.

15.

Novel channel-mediated choline transport in cholinergic neurons of the mouse retina.

Ishii T, Homma K, Mano A, Akagi T, Shigematsu Y, Shimoda Y, Inoue H, Kakinuma Y, Kaneda M.

J Neurophysiol. 2017 Oct 1;118(4):1952-1961. doi: 10.1152/jn.00506.2016. Epub 2017 Jul 12.

16.

Erratum to: Various Regulatory Modes for Circadian Rhythmicity and Sexual Dimorphism in the Non-Neuronal Cardiac Cholinergic System.

Oikawa S, Kai Y, Mano A, Ohata H, Nemoto T, Kakinuma Y.

J Cardiovasc Transl Res. 2017 Aug;10(4):435. doi: 10.1007/s12265-017-9760-2. No abstract available.

PMID:
28643179
17.

Various Regulatory Modes for Circadian Rhythmicity and Sexual Dimorphism in the Non-Neuronal Cardiac Cholinergic System.

Oikawa S, Kai Y, Mano A, Ohata H, Nemoto T, Kakinuma Y.

J Cardiovasc Transl Res. 2017 Aug;10(4):411-422. doi: 10.1007/s12265-017-9750-4. Epub 2017 May 11. Erratum in: J Cardiovasc Transl Res. 2017 Jun 22;:.

PMID:
28497301
18.

Lack of interleukin-13 receptor α1 delays the loss of dopaminergic neurons during chronic stress.

Mori S, Sugama S, Nguyen W, Michel T, Sanna MG, Sanchez-Alavez M, Cintron-Colon R, Moroncini G, Kakinuma Y, Maher P, Conti B.

J Neuroinflammation. 2017 Apr 21;14(1):88. doi: 10.1186/s12974-017-0862-1.

19.

Corrigendum to "Chronic restraint stress triggers dopaminergic and noradrenergic neurodegeneration: Possible role of chronic stress in the onset of Parkinson's disease" [Brain Behav. Immun. 51 (2016) 39-46].

Sugama S, Sekiyama K, Kodama T, Takamatsu Y, Takenouchi T, Hashimoto M, Conti B, Kakinuma Y.

Brain Behav Immun. 2017 Mar;61:389. doi: 10.1016/j.bbi.2016.12.009. Epub 2016 Dec 28. No abstract available.

20.

Functional identification of AtAVT3, a family of vacuolar amino acid transporters, in Arabidopsis.

Fujiki Y, Teshima H, Kashiwao S, Kawano-Kawada M, Ohsumi Y, Kakinuma Y, Sekito T.

FEBS Lett. 2017 Jan;591(1):5-15. doi: 10.1002/1873-3468.12507. Epub 2016 Dec 19.

21.

Operating principles of rotary molecular motors: differences between F1 and V1 motors.

Yamato I, Kakinuma Y, Murata T.

Biophys Physicobiol. 2016 Feb 27;13:37-44. eCollection 2016. Review.

22.
23.

Crystal structures of the ATP-binding and ADP-release dwells of the V1 rotary motor.

Suzuki K, Mizutani K, Maruyama S, Shimono K, Imai FL, Muneyuki E, Kakinuma Y, Ishizuka-Katsura Y, Shirouzu M, Yokoyama S, Yamato I, Murata T.

Nat Commun. 2016 Oct 27;7:13235. doi: 10.1038/ncomms13235.

24.

Distribution of Corticotrophin-Releasing Factor Type 1 Receptor-Like Immunoreactivity in the Rat Pituitary.

Mano-Otagiri A, Nemoto T, Yamauchi N, Kakinuma Y, Shibasaki T.

J Neuroendocrinol. 2016 Dec;28(12). doi: 10.1111/jne.12440.

PMID:
27801962
25.

The amino-terminal hydrophilic region of the vacuolar transporter Avt3p is dispensable for the vacuolar amino acid compartmentalization of Schizosaccharomyces pombe.

Kawano-Kawada M, Chardwiriyapreecha S, Manabe K, Sekito T, Akiyama K, Takegawa K, Kakinuma Y.

Biosci Biotechnol Biochem. 2016 Dec;80(12):2291-2297. Epub 2016 Aug 24.

PMID:
27555098
26.

Non-neuronal cardiac cholinergic system influences CNS via the vagus nerve to acquire a stress-refractory propensity.

Oikawa S, Kai Y, Tsuda M, Ohata H, Mano A, Mizoguchi N, Sugama S, Nemoto T, Suzuki K, Kurabayashi A, Muramoto K, Kaneda M, Kakinuma Y.

Clin Sci (Lond). 2016 Nov 1;130(21):1913-28. doi: 10.1042/CS20160277. Epub 2016 Aug 15.

PMID:
27528769
27.

Donepezil, an acetylcholinesterase inhibitor, attenuates LPS-induced inflammatory response in murine macrophage cell line RAW 264.7 through inhibition of nuclear factor kappa B translocation.

Arikawa M, Kakinuma Y, Noguchi T, Todaka H, Sato T.

Eur J Pharmacol. 2016 Oct 15;789:17-26. doi: 10.1016/j.ejphar.2016.06.053. Epub 2016 Jun 30.

PMID:
27373848
28.
29.

Ypq3p-dependent histidine uptake by the vacuolar membrane vesicles of Saccharomyces cerevisiae.

Manabe K, Kawano-Kawada M, Ikeda K, Sekito T, Kakinuma Y.

Biosci Biotechnol Biochem. 2016 Jun;80(6):1125-30. doi: 10.1080/09168451.2016.1141041. Epub 2016 Mar 1.

PMID:
26928127
30.

Vba4p, a vacuolar membrane protein, is involved in the drug resistance and vacuolar morphology of Saccharomyces cerevisiae.

Kawano-Kawada M, Pongcharoen P, Kawahara R, Yasuda M, Yamasaki T, Akiyama K, Sekito T, Kakinuma Y.

Biosci Biotechnol Biochem. 2016;80(2):279-87. doi: 10.1080/09168451.2015.1083401. Epub 2015 Sep 1.

PMID:
26325352
31.

Chronic restraint stress triggers dopaminergic and noradrenergic neurodegeneration: Possible role of chronic stress in the onset of Parkinson's disease.

Sugama S, Sekiyama K, Kodama T, Takamatsu Y, Takenouchi T, Hashimoto M, Bruno C, Kakinuma Y.

Brain Behav Immun. 2016 Jan;51:39-46. doi: 10.1016/j.bbi.2015.08.015. Epub 2015 Aug 17. Erratum in: Brain Behav Immun. 2017 Mar;61:389.

32.

Functional Expression and Characterization of Schizosaccharomyces pombe Avt3p as a Vacuolar Amino Acid Exporter in Saccharomyces cerevisiae.

Chardwiriyapreecha S, Manabe K, Iwaki T, Kawano-Kawada M, Sekito T, Lunprom S, Akiyama K, Takegawa K, Kakinuma Y.

PLoS One. 2015 Jun 17;10(6):e0130542. doi: 10.1371/journal.pone.0130542. eCollection 2015.

33.

Characterization of vacuolar amino acid transporter from Fusarium oxysporum in Saccharomyces cerevisiae.

Lunprom S, Pongcharoen P, Sekito T, Kawano-Kawada M, Kakinuma Y, Akiyama K.

Biosci Biotechnol Biochem. 2015;79(12):1972-9. doi: 10.1080/09168451.2015.1058703. Epub 2015 Jun 17.

PMID:
26083447
34.

Remote ischemic preconditioning with a specialized protocol activates the non-neuronal cardiac cholinergic system and increases ATP content in the heart.

Oikawa S, Mano A, Takahashi R, Kakinuma Y.

Int Immunopharmacol. 2015 Nov;29(1):181-4. doi: 10.1016/j.intimp.2015.06.004. Epub 2015 Jun 11.

PMID:
26072685
35.

Future perspectives of a cardiac non-neuronal acetylcholine system targeting cardiovascular diseases as an adjunctive tool for metabolic intervention.

Kakinuma Y.

Int Immunopharmacol. 2015 Nov;29(1):185-8. doi: 10.1016/j.intimp.2015.05.029. Epub 2015 May 28. Review.

PMID:
26028150
36.

Nicotinic receptor-dependent and -independent effects of galantamine, an acetylcholinesterase inhibitor, on the non-neuronal acetylcholine system in C2C12 cells.

Oikawa S, Mano A, Iketani M, Kakinuma Y.

Int Immunopharmacol. 2015 Nov;29(1):31-5. doi: 10.1016/j.intimp.2015.04.057. Epub 2015 May 12.

PMID:
25979761
37.

Characterization of Avt1p as a vacuolar proton/amino acid antiporter in Saccharomyces cerevisiae.

Tone J, Yoshimura A, Manabe K, Murao N, Sekito T, Kawano-Kawada M, Kakinuma Y.

Biosci Biotechnol Biochem. 2015;79(5):782-9. doi: 10.1080/09168451.2014.998621. Epub 2015 Mar 9.

PMID:
25747199
38.

Impaired miR449a-induced downregulation of Crhr1 expression in low-birth-weight rats.

Nemoto T, Kakinuma Y, Shibasaki T.

J Endocrinol. 2015 Feb;224(2):195-203. doi: 10.1530/JOE-14-0537. Epub 2014 Dec 5.

PMID:
25480379
39.

A concept of a nonneuronal cardiac cholinergic system.

Kakinuma Y.

J Nippon Med Sch. 2014;81(5):296-7. No abstract available.

40.

A vacuolar membrane protein Avt7p is involved in transport of amino acid and spore formation in Saccharomyces cerevisiae.

Tone J, Yamanaka A, Manabe K, Murao N, Kawano-Kawada M, Sekito T, Kakinuma Y.

Biosci Biotechnol Biochem. 2015;79(2):190-5. doi: 10.1080/09168451.2014.963501. Epub 2014 Sep 30.

PMID:
25266154
41.

Loss of ATP-dependent lysine uptake in the vacuolar membrane vesicles of Saccharomyces cerevisiae ypq1∆ mutant.

Sekito T, Nakamura K, Manabe K, Tone J, Sato Y, Murao N, Kawano-Kawada M, Kakinuma Y.

Biosci Biotechnol Biochem. 2014;78(7):1199-202. doi: 10.1080/09168451.2014.918489. Epub 2014 Jun 17.

PMID:
25229858
42.

A non-neuronal cholinergic system regulates cellular ATP levels to maintain cell viability.

Oikawa S, Iketani M, Kakinuma Y.

Cell Physiol Biochem. 2014;34(3):781-9. doi: 10.1159/000363042. Epub 2014 Aug 19.

43.

Donepezil can improve ischemic muscle atrophy by activating angiomyogenic properties of satellite cells.

Noguchi T, Kakinuma Y, Arikawa M, Okazaki K, Hoshino E, Iiyama T, Kubo T, Kitaoka H, Doi Y, Sato T.

Circ J. 2014;78(9):2317-24. Epub 2014 Jul 25.

44.

Vacuolar transporter Avt4 is involved in excretion of basic amino acids from the vacuoles of Saccharomyces cerevisiae.

Sekito T, Chardwiriyapreecha S, Sugimoto N, Ishimoto M, Kawano-Kawada M, Kakinuma Y.

Biosci Biotechnol Biochem. 2014;78(6):969-75. doi: 10.1080/09168451.2014.910095. Epub 2014 Jun 13.

PMID:
25036121
45.

Antimuscle atrophy effect of nicotine targets muscle satellite cells partly through an α7 nicotinic receptor in a murine hindlimb ischemia model.

Kakinuma Y, Noguchi T, Okazaki K, Oikawa S, Iketani M, Kurabayashi A, Furihata M, Sato T.

Transl Res. 2014 Jul;164(1):32-45. doi: 10.1016/j.trsl.2014.02.005. Epub 2014 Apr 24. Erratum in: Transl Res. 2014 Dec;164(6):515. Kurabayashi, Mutsumi [corrected to Kurabayashi, Atsushi].

PMID:
24811002
46.

Tributyltin induces cell cycle arrest at G1 phase in the yeast Saccharomyces cerevisiae.

Sekito T, Sugimoto N, Ishimoto M, Kawano-Kawada M, Akiyama K, Nishimoto S, Sugahara T, Kakinuma Y.

J Toxicol Sci. 2014 Apr;39(2):311-7.

47.

Mutant LV(476-7)AA of A-subunit of Enterococcus hirae V1-ATPase: High affinity of A3B3 complex to DF axis and low ATPase activity.

Alam J, Yamato I, Arai S, Saijo S, Mizutani K, Ishizuka-Katsura Y, Ohsawa N, Terada T, Shirouzu M, Yokoyama S, Iwata S, Kakinuma Y, Murata T.

Springerplus. 2013 Dec 27;2:689. doi: 10.1186/2193-1801-2-689. eCollection 2013.

48.

Loose binding of the DF axis with the A3B3 complex stimulates the initial activity of Enterococcus hirae V1-ATPase.

Alam MJ, Arai S, Saijo S, Suzuki K, Mizutani K, Ishizuka-Katsura Y, Ohsawa N, Terada T, Shirouzu M, Yokoyama S, Iwata S, Kakinuma Y, Yamato I, Murata T.

PLoS One. 2013 Sep 13;8(9):e74291. doi: 10.1371/journal.pone.0074291. eCollection 2013.

49.

Functional expression of Schizosaccharomyces pombe Vba2p in the vacuolar membrane of Saccharomyces cerevisiae.

Pongcharoen P, Kawano-Kawada M, Iwaki T, Sugimoto N, Sekito T, Akiyama K, Takegawa K, Kakinuma Y.

Biosci Biotechnol Biochem. 2013;77(9):1988-90. Epub 2013 Sep 7.

50.

Conditional VHL gene deletion causes hypoglycemic death associated with disproportionately increased glucose uptake by hepatocytes through an upregulated IGF-I receptor.

Kurabayashi A, Kakinuma Y, Morita T, Inoue K, Sato T, Furihata M.

PLoS One. 2013 Jul 9;8(7):e69139. doi: 10.1371/journal.pone.0069139. Print 2013.

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