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Items: 1 to 50 of 147

1.

Ciliated muconodular papillary tumors of the lung: Cytologic features and diagnostic pitfalls in intraoperative examinations.

Mikubo M, Maruyama R, Kakinuma H, Yoshida T, Satoh Y.

Diagn Cytopathol. 2019 Jul;47(7):716-719. doi: 10.1002/dc.24169. Epub 2019 Mar 8.

PMID:
30848550
2.

Discovery of potent, low-absorbable sodium-dependent glucose cotransporter 1 (SGLT1) inhibitor SGL5213 for type 2 diabetes treatment.

Kuroda S, Kobashi Y, Oi T, Kawabe K, Shiozawa F, Okumura-Kitajima L, Sugisaki-Kitano M, Io F, Yamamoto K, Kakinuma H.

Bioorg Med Chem. 2019 Jan 15;27(2):394-409. doi: 10.1016/j.bmc.2018.12.015. Epub 2018 Dec 11.

PMID:
30579799
3.

Discovery of a potent, low-absorbable sodium-dependent glucose cotransporter 1 (SGLT1) inhibitor (TP0438836) for the treatment of type 2 diabetes.

Kuroda S, Kobashi Y, Oi T, Amada H, Okumura-Kitajima L, Io F, Yamamto K, Kakinuma H.

Bioorg Med Chem Lett. 2018 Dec 1;28(22):3534-3539. doi: 10.1016/j.bmcl.2018.09.035. Epub 2018 Sep 29.

PMID:
30297284
4.

Optical measurement of neuronal activity in the developing cerebellum of zebrafish using voltage-sensitive dye imaging.

Okumura K, Kakinuma H, Amo R, Okamoto H, Yamasu K, Tsuda S.

Neuroreport. 2018 Nov 7;29(16):1349-1354. doi: 10.1097/WNR.0000000000001113.

PMID:
30192301
5.

Discovery of novel 2-[(4-hydroxy-6-oxo-2,3-dihydro-1H-pyridine-5-carbonyl)amino]acetic acid derivatives as HIF prolyl hydroxylase inhibitors for treatment of renal anemia.

Hamada M, Takayama T, Shibata T, Hiratate A, Takahashi M, Yashiro M, Takayama N, Okumura-Kitajima L, Koretsune H, Kajiyama H, Naruse T, Kato S, Takano H, Kakinuma H.

Bioorg Med Chem Lett. 2018 Jun 1;28(10):1725-1730. doi: 10.1016/j.bmcl.2018.04.039. Epub 2018 Apr 16.

PMID:
29681433
6.

Optical interrogation of neuronal circuitry in zebrafish using genetically encoded voltage indicators.

Miyazawa H, Okumura K, Hiyoshi K, Maruyama K, Kakinuma H, Amo R, Okamoto H, Yamasu K, Tsuda S.

Sci Rep. 2018 Apr 16;8(1):6048. doi: 10.1038/s41598-018-23906-1.

7.

Design, synthesis and biological evaluation of novel 7-azaspiro[3.5]nonane derivatives as GPR119 agonists.

Matsuda D, Kawamura M, Kobashi Y, Shiozawa F, Suga Y, Fusegi K, Nishimoto S, Kimura K, Miyoshi M, Takayama N, Kakinuma H, Ohtake N.

Bioorg Med Chem. 2018 May 1;26(8):1832-1847. doi: 10.1016/j.bmc.2018.02.032. Epub 2018 Feb 20.

PMID:
29486951
8.

Novel 3H-[1,2,3]triazolo[4,5-c]pyridine derivatives as GPR119 agonists: Synthesis and structure-activity/solubility relationships.

Matsuda D, Kobashi Y, Mikami A, Kawamura M, Shiozawa F, Kawabe K, Hamada M, Nishimoto S, Kimura K, Miyoshi M, Takayama N, Kakinuma H, Ohtake N.

Bioorg Med Chem. 2017 Aug 15;25(16):4339-4354. doi: 10.1016/j.bmc.2017.06.014. Epub 2017 Jun 13.

PMID:
28662959
9.

Immature Core protein of hepatitis C virus induces an unfolded protein response through inhibition of ERAD-L in a yeast model system.

Takahashi S, Sato N, Kikuchi J, Kakinuma H, Okawa J, Masuyama Y, Iwasa S, Irokawa H, Hwang GW, Naganuma A, Kohara M, Kuge S.

Genes Cells. 2017 Feb;22(2):160-173. doi: 10.1111/gtc.12464. Epub 2017 Jan 18.

10.

Delayed Propionibacterium acnes surgical site infections occur only in the presence of an implant.

Shiono Y, Ishii K, Nagai S, Kakinuma H, Sasaki A, Funao H, Kuramoto T, Yoshioka K, Ishihama H, Isogai N, Takeshima K, Tsuji T, Okada Y, Koyasu S, Nakamura M, Toyama Y, Aizawa M, Matsumoto M.

Sci Rep. 2016 Sep 12;6:32758. doi: 10.1038/srep32758.

11.

Design and synthesis of 1H-pyrazolo[3,4-c]pyridine derivatives as a novel structural class of potent GPR119 agonists.

Matsuda D, Kobashi Y, Mikami A, Kawamura M, Shiozawa F, Kawabe K, Hamada M, Oda K, Nishimoto S, Kimura K, Miyoshi M, Takayama N, Kakinuma H, Ohtake N.

Bioorg Med Chem Lett. 2016 Aug 1;26(15):3441-6. doi: 10.1016/j.bmcl.2016.06.050. Epub 2016 Jun 20.

PMID:
27390068
12.

The habenulo-raphe serotonergic circuit encodes an aversive expectation value essential for adaptive active avoidance of danger.

Amo R, Fredes F, Kinoshita M, Aoki R, Aizawa H, Agetsuma M, Aoki T, Shiraki T, Kakinuma H, Matsuda M, Yamazaki M, Takahoko M, Tsuboi T, Higashijima S, Miyasaka N, Koide T, Yabuki Y, Yoshihara Y, Fukai T, Okamoto H.

Neuron. 2014 Dec 3;84(5):1034-48. doi: 10.1016/j.neuron.2014.10.035. Epub 2014 Nov 20.

13.

Antibacterial polyetheretherketone implants immobilized with silver ions based on chelate-bonding ability of inositol phosphate: processing, material characterization, cytotoxicity, and antibacterial properties.

Kakinuma H, Ishii K, Ishihama H, Honda M, Toyama Y, Matsumoto M, Aizawa M.

J Biomed Mater Res A. 2015 Jan;103(1):57-64. doi: 10.1002/jbm.a.35157. Epub 2014 Mar 19.

PMID:
24616120
14.

Discriminant analysis between malignant mesothelioma and reactive mesothelium using nuclear three-dimensional analysis is useful for morphologically suspicious cases.

Washiya K, Mizuki Y, Nakamura M, Kakinuma H, Saegusa M, Satoh Y, Yoshioka H, Watanabe J.

Acta Cytol. 2013;57(5):509-15. doi: 10.1159/000351614. Epub 2013 Sep 7.

PMID:
24021244
15.

Differential diagnosis of reactive mesothelial cells and malignant mesothelioma cells using the cell proliferation markers minichromosome maintenance protein 7, geminin, topoisomerase II alpha and Ki-67.

Kimura F, Okayasu I, Kakinuma H, Satoh Y, Kuwao S, Saegusa M, Watanabe J.

Acta Cytol. 2013;57(4):384-90. doi: 10.1159/000350262. Epub 2013 Jul 12.

PMID:
23860238
16.

Steroid sulphatase and oestrogen sulphotransferase in human non-small-cell lung carcinoma.

Iida S, Kakinuma H, Miki Y, Abe K, Sakurai M, Suzuki S, Niikawa H, Akahira J, Suzuki T, Sasano H.

Br J Cancer. 2013 Apr 16;108(7):1415-24. doi: 10.1038/bjc.2013.84. Epub 2013 Mar 26.

17.

Immunohistochemical, molecular, and clinicopathological analyses of urothelial carcinoma, micropapillary variant.

Ishii S, Ohbu M, Toomine Y, Nishimura Y, Hattori M, Yokoyama M, Toyonaga M, Kakinuma H, Matsumoto K.

Pathol Int. 2011 Dec;61(12):723-30. doi: 10.1111/j.1440-1827.2011.02731.x. Epub 2011 Oct 3.

PMID:
22126379
18.

Canopy1, a positive feedback regulator of FGF signaling, controls progenitor cell clustering during Kupffer's vesicle organogenesis.

Matsui T, Thitamadee S, Murata T, Kakinuma H, Nabetani T, Hirabayashi Y, Hirate Y, Okamoto H, Bessho Y.

Proc Natl Acad Sci U S A. 2011 Jun 14;108(24):9881-6. doi: 10.1073/pnas.1017248108. Epub 2011 May 31.

19.

Cytological significance of abnormal squamous cells in urinary cytology.

Hattori M, Nishimura Y, Toyonaga M, Kakinuma H, Matsumoto K, Ohbu M.

Diagn Cytopathol. 2012 Sep;40(9):798-803. doi: 10.1002/dc.21645. Epub 2011 Feb 9.

PMID:
21309015
20.

(1S)-1,5-anhydro-1-[5-(4-ethoxybenzyl)-2-methoxy-4-methylphenyl]-1-thio-D-glucitol (TS-071) is a potent, selective sodium-dependent glucose cotransporter 2 (SGLT2) inhibitor for type 2 diabetes treatment.

Kakinuma H, Oi T, Hashimoto-Tsuchiya Y, Arai M, Kawakita Y, Fukasawa Y, Iida I, Hagima N, Takeuchi H, Chino Y, Asami J, Okumura-Kitajima L, Io F, Yamamoto D, Miyata N, Takahashi T, Uchida S, Yamamoto K.

J Med Chem. 2010 Apr 22;53(8):3247-61. doi: 10.1021/jm901893x.

PMID:
20302302
21.

An anatomical basis for blocking of the deep cervical plexus and cervical sympathetic tract using an ultrasound-guided technique.

Usui Y, Kobayashi T, Kakinuma H, Watanabe K, Kitajima T, Matsuno K.

Anesth Analg. 2010 Mar 1;110(3):964-8. doi: 10.1213/ANE.0b013e3181c91ea0. Epub 2009 Dec 15.

PMID:
20008914
22.

Highly concordant coexpression of aromatase and estrogen receptor beta in non-small cell lung cancer.

Abe K, Miki Y, Ono K, Mori M, Kakinuma H, Kou Y, Kudo N, Koguchi M, Niikawa H, Suzuki S, Evans DB, Sugawara S, Suzuki T, Sasano H.

Hum Pathol. 2010 Feb;41(2):190-8. doi: 10.1016/j.humpath.2009.07.010. Epub 2009 Oct 1.

PMID:
19800101
23.

CW transillumination imaging by extracting weakly scattered light from strongly diffused light.

Takagi K, Kakinuma H, Kato Y, Shimizu K.

Opt Express. 2009 May 11;17(10):8332-42.

PMID:
19434166
24.

Analysis of children with Chlamydophila (Chlamydia) pneumoniae and Mycoplasma pneumoniae respiratoryinfections by real-time PCR assay and serological tests.

Otomo S, Yamamura J, Hayashi E, Nakamura T, Kakinuma H, Nakamoto Y, Takahashi H, Karasawa T.

APMIS. 2008 Jun;116(6):477-83.

PMID:
18754321
25.

Copy-number variations associated with autism spectrum disorder.

Kakinuma H, Sato H.

Pharmacogenomics. 2008 Aug;9(8):1143-54. doi: 10.2217/14622416.9.8.1143. Review.

PMID:
18681787
26.

Variation in GABA-A subunit gene copy number in an autistic patient with mosaic 4 p duplication (p12p16).

Kakinuma H, Ozaki M, Sato H, Takahashi H.

Am J Med Genet B Neuropsychiatr Genet. 2008 Sep 5;147B(6):973-5. doi: 10.1002/ajmg.b.30663.

PMID:
18163449
27.

Basement membrane-like substance in cytologic diagnosis in clear cell adenocarcinoma of the minor salivary gland of the palate. A case report.

Kobayashi M, Hattori M, Miyamoto T, Kakinuma H, Watanabe J, Iwabuchi K, Nishimura Y, Jobo T, Kuramoto H.

Acta Cytol. 2007 Nov-Dec;51(6):916-20.

PMID:
18077986
28.

Recovery from lethal arrhythmia after weight gain in a patient with an eating disorder and epilepsy.

Akita C, Nakamura T, Sato H, Kakinuma H.

Pediatr Cardiol. 2008 May;29(3):673-5. Epub 2007 Nov 13.

PMID:
17999104
29.

Mechanistic analysis of the phosphonate transition-state analogue-derived catalytic and non-catalytic antibody.

Nishi Y, Yamamoto N, Shimazaki K, Takahashi-Ando N, Kakinuma H, Jialin S, Ruzheinikov SN, Muranova TA, Rice DW, Kajihara Y.

J Biochem. 2007 Oct;142(4):421-33.

PMID:
17981825
30.

An inherited disorder characterized by repeated episodes of bilateral ballism: a case report.

Kakinuma H, Hori A, Itoh M, Nakamura T, Takahashi H.

Mov Disord. 2007 Oct 31;22(14):2110-2.

PMID:
17894338
31.

Cell cannibalism and nucleus-fragmented cells in voided urine: useful parameters for cytologic diagnosis of low-grade urothelial carcinoma.

Hattori M, Nishino Y, Kakinuma H, Matsumoto K, Ohbu M, Okayasu I.

Acta Cytol. 2007 Jul-Aug;51(4):547-51.

PMID:
17718119
32.

Novel mutation of methylmalonyl-CoA mutase gene causing the mut0 form of methylmalonic acidemia in a Japanese girl.

Oyama C, Takahashi T, Matsumori M, Shoji Y, Tajima G, Sakura N, Hasegawa Y, Yamaguchi S, Kakinuma H, Takada G.

Pediatr Int. 2007 Apr;49(2):232-4. No abstract available.

PMID:
17445044
33.

Low concentrations of the histone deacetylase inhibitor, depsipeptide, enhance the effects of gemcitabine and docetaxel in hormone refractory prostate cancer cells.

Kanzaki M, Kakinuma H, Kumazawa T, Inoue T, Saito M, Narita S, Yuasa T, Tsuchiya N, Habuchi T.

Oncol Rep. 2007 Apr;17(4):761-7.

PMID:
17342312
34.

Vasculitis induced by immunization with Bacillus Calmette-Guérin followed by atypical mycobacterium antigen: a new mouse model for Kawasaki disease.

Nakamura T, Yamamura J, Sato H, Kakinuma H, Takahashi H.

FEMS Immunol Med Microbiol. 2007 Apr;49(3):391-7. Epub 2007 Feb 12.

35.

Structure-activity relationships of novel piperazines as antagonists for the melanocortin-4 receptor.

Nozawa D, Okubo T, Ishii T, Kakinuma H, Chaki S, Okuyama S, Nakazato A.

Bioorg Med Chem. 2007 Mar 1;15(5):1989-2005. Epub 2006 Dec 30.

PMID:
17234422
36.

[Adaptation of English-written health-related quality of life measure for children].

Kakinuma H, Nakai A, Honma K, Yagi N, Niida Y, Matsushima A, Tsuda H, Takizawa N.

No To Hattatsu. 2007 Jan;39(1):66-7. Japanese. No abstract available.

PMID:
17228823
37.

Valproate hepatotoxicity in a 5-year-old boy with cerebral palsy due to neonatal asphyxia.

Kakinuma H, Fujiki T, Nakamura T, Takahashi H.

Pediatr Int. 2006 Dec;48(6):631-3. No abstract available.

PMID:
17168987
38.

Molecular mechanisms of improvement of hydrolytic antibody 6D9 by site-directed mutagenesis.

Takahashi-Ando N, Shimazaki K, Kakinuma H, Fujii I, Nishi Y.

J Biochem. 2006 Oct;140(4):509-15. Epub 2006 Aug 18.

PMID:
16921165
39.

Association of XRCC1 gene polymorphisms with the susceptibility and chromosomal aberration of testicular germ cell tumors.

Tsuchiya N, Mishina M, Narita S, Kumazawa T, Inoue T, Horikawa Y, Kakinuma H, Yuasa T, Matsuura S, Satoh S, Ogawa O, Habuchi T.

Int J Oncol. 2006 May;28(5):1217-23.

PMID:
16596238
40.

Erosive velvety lesion on the vulva--vulvar basal cell carcinoma.

Suda T, Kakinuma H.

Arch Dermatol. 2006 Mar;142(3):385-90. No abstract available.

PMID:
16549720
41.

Outcome of right hand-assisted retroperitoneoscopic living donor nephrectomy.

Narita S, Inoue T, Matsuura S, Horikawa Y, Kakinuma H, Saito M, Kumazawa T, Tsuchiya N, Satoh S, Habuchi T.

Urology. 2006 Mar;67(3):496-500; discussion 500-1.

PMID:
16527565
42.

Three novel and six common mutations in 11 patients with methylmalonic acidemia.

Kobayashi A, Kakinuma H, Takahashi H.

Pediatr Int. 2006 Feb;48(1):1-4. Erratum in: Pediatr Int. 2007 Feb;49(1):122.

PMID:
16490061
43.

Syndromic craniosynostosis with elbow joint contracture.

Akai T, Yamamoto K, Iizuka H, Kawakami S, Yoshida J, Kakinuma H, Yaguchi Y, Ozawa T.

Pediatr Neurosurg. 2006;42(2):108-12.

PMID:
16465081
44.

Clinical and genetic risk factors for posttransplant diabetes mellitus in adult renal transplant recipients treated with tacrolimus.

Numakura K, Satoh S, Tsuchiya N, Horikawa Y, Inoue T, Kakinuma H, Matsuura S, Saito M, Tada H, Suzuki T, Habuchi T.

Transplantation. 2005 Nov 27;80(10):1419-24.

PMID:
16340785
45.

Association of BCL10 germ line polymorphisms on chromosome 1p with advanced stage testicular germ cell tumor patients.

Inoue T, Ito T, Narita S, Horikawa Y, Tsuchiya N, Kakinuma H, Mishina M, Nakamura E, Kato T, Ogawa O, Habuchi T.

Cancer Lett. 2006 Aug 18;240(1):41-7. Epub 2005 Oct 17.

PMID:
16229939
46.
47.

Incidence and risk factors of clinical characteristics, tacrolimus pharmacokinetics, and related genomic polymorphisms for posttransplant diabetes mellitus in the early stage of renal transplant recipients.

Numakura K, Satoh S, Tsuchiya N, Horikawa Y, Inoue T, Kakinuma H, Togashi H, Matsuura S, Tada H, Suzuki T, Habuchi T.

Transplant Proc. 2005 May;37(4):1865-7.

PMID:
15919487
48.

Enhanced JNK activation by NESK without kinase activity upon caspase-mediated cleavage during apoptosis.

Kakinuma H, Inomata H, Kitamura N.

Cell Signal. 2005 Nov;17(11):1439-48.

PMID:
15913957
49.

[A case of fibroepithelial polyp of the ureter resected ureteroscopically].

Numakura K, Tsuchiya N, Inoue T, Horikawa Y, Kakinuma H, Togashi H, Matsuura S, Ohyama C, Satoh S, Sato K, Habuchi T, Noto H.

Hinyokika Kiyo. 2005 Apr;51(4):277-81. Review. Japanese.

50.

CYP3A5 gene polymorphism and risk of prostate cancer in a Japanese population.

Zhenhua L, Tsuchiya N, Narita S, Inoue T, Horikawa Y, Kakinuma H, Kato T, Ogawa O, Habuchi T.

Cancer Lett. 2005 Jul 28;225(2):237-43.

PMID:
15876487

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