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Items: 35

1.

Intestinal secretion of indoxyl sulfate as a possible compensatory excretion pathway in chronic kidney disease.

Morimoto K, Tominaga Y, Agatsuma Y, Miyamoto M, Kashiwagura S, Takahashi A, Sano Y, Yano K, Kakinuma C, Ogihara T, Tomita M.

Biopharm Drug Dispos. 2018 Jul;39(7):328-334. doi: 10.1002/bdd.2149. Epub 2018 Aug 13.

PMID:
29975986
2.

Dedifferentiated retroperitoneal liposarcoma spontaneously occurring in an aged SD rat.

Naito T, Saito T, Higuchi T, Inomata A, Hayashi T, Shimada Y, Yamauchi-Ohguchi A, Kenmochi S, Kakinuma C, Yao T.

J Toxicol Pathol. 2018 Apr;31(2):141-146. doi: 10.1293/tox.2017-0055. Epub 2018 Jan 6.

3.

FF-10502, an Antimetabolite with Novel Activity on Dormant Cells, Is Superior to Gemcitabine for Targeting Pancreatic Cancer Cells.

Mima S, Kakinuma C, Higuchi T, Saeki K, Yamada T, Uematsu R, Ishino M, Kito N, Nishikawa H, Kuniyoshi H, Matsumoto T, Fujiwara H, Paradiso LJ, Shimada Y, Iwamura H.

J Pharmacol Exp Ther. 2018 Jul;366(1):125-135. doi: 10.1124/jpet.118.248740. Epub 2018 Apr 13.

PMID:
29653962
4.

Investigation into metastatic processes and the therapeutic effects of gemcitabine on human pancreatic cancer using an orthotopic SUIT-2 pancreatic cancer mouse model.

Higuchi T, Yokobori T, Naito T, Kakinuma C, Hagiwara S, Nishiyama M, Asao T.

Oncol Lett. 2018 Mar;15(3):3091-3099. doi: 10.3892/ol.2017.7722. Epub 2017 Dec 29.

5.

Cholesterol-Lowering Effect of Calcium Alginate in Rats.

Idota Y, Kogure Y, Kato T, Ogawa M, Kobayashi S, Kakinuma C, Yano K, Arakawa H, Miyajima C, Kasahara F, Ogihara T.

Biol Pharm Bull. 2016;39(1):62-7. doi: 10.1248/bpb.b15-00503.

6.

Improvement in Human Immune Function with Changes in Intestinal Microbiota by Salacia reticulata Extract Ingestion: A Randomized Placebo-Controlled Trial.

Oda Y, Ueda F, Utsuyama M, Kamei A, Kakinuma C, Abe K, Hirokawa K.

PLoS One. 2015 Dec 2;10(12):e0142909. doi: 10.1371/journal.pone.0142909. eCollection 2015.

7.

A subchronic oral toxicity study of Salacia reticulata extract powder in rats.

Oda Y, Yuasa A, Ueda F, Kakinuma C.

Toxicol Rep. 2015 Jul 26;2:1136-1144. doi: 10.1016/j.toxrep.2015.07.001. eCollection 2015.

8.

Alginate enhances excretion and reduces absorption of strontium and cesium in rats.

Idota Y, Harada H, Tomono T, Morimoto K, Kobayashi S, Kakinuma C, Miyajima C, Kasahara F, Ogihara T.

Biol Pharm Bull. 2013;36(3):485-91. Epub 2013 Jan 15.

9.

Developmental changes of brain distribution and localization of oseltamivir and its active metabolite Ro 64-0802 in rats.

Morimoto K, Nagami T, Matsumoto N, Wada S, Kano T, Kakinuma C, Ogihara T.

J Toxicol Sci. 2012;37(6):1217-23.

10.

Identification of IAA transport inhibitors including compounds affecting cellular PIN trafficking by two chemical screening approaches using maize coleoptile systems.

Nishimura T, Matano N, Morishima T, Kakinuma C, Hayashi K, Komano T, Kubo M, Hasebe M, Kasahara H, Kamiya Y, Koshiba T.

Plant Cell Physiol. 2012 Oct;53(10):1671-82. doi: 10.1093/pcp/pcs112. Epub 2012 Aug 7.

PMID:
22875609
11.

Evaluation of high-throughput screening for in vitro micronucleus test using fluorescence-based cell imaging.

Shibai-Ogata A, Kakinuma C, Hioki T, Kasahara T.

Mutagenesis. 2011 Nov;26(6):709-19. doi: 10.1093/mutage/ger037. Epub 2011 Jul 10.

PMID:
21745803
12.

Biochemical investigation and gene expression analysis of the immunostimulatory functions of an edible Salacia extract in rat small intestine.

Oda Y, Ueda F, Kamei A, Kakinuma C, Abe K.

Biofactors. 2011 Jan-Feb;37(1):31-9. doi: 10.1002/biof.132. Epub 2010 Nov 29.

PMID:
21328625
13.

Enhancement of drug solubility and absorption by copolymers of 2-methacryloyloxyethyl phosphorylcholine and n-butyl methacrylate.

Kano T, Kakinuma C, Wada S, Morimoto K, Ogihara T.

Drug Metab Pharmacokinet. 2011;26(1):79-86. Epub 2010 Nov 12.

14.

Evaluation of the inhibitory effect of dihydropyridines on N-type calcium channel by virtual three-dimensional pharmacophore modeling.

Ogihara T, Kano T, Kakinuma C.

Arzneimittelforschung. 2009;59(6):283-8. doi: 10.1055/s-0031-1296398.

PMID:
19634509
15.

Oseltamivir (Tamiflu) efflux transport at the blood-brain barrier via P-glycoprotein.

Morimoto K, Nakakariya M, Shirasaka Y, Kakinuma C, Fujita T, Tamai I, Ogihara T.

Drug Metab Dispos. 2008 Jan;36(1):6-9. Epub 2007 Oct 16.

16.

Role of fibrosis-related genes and pancreatic duct obstruction in rat pancreatitis models: implications for chronic pancreatitis.

Miyauchi M, Suda K, Kuwayama C, Abe H, Kakinuma C.

Histol Histopathol. 2007 Oct;22(10):1119-27. doi: 10.14670/HH-22.1119.

PMID:
17616939
17.

Improving effect of ethyl eicosapentanoate on statin-induced rhabdomyolysis in Eisai hyperbilirubinemic rats.

Naba H, Kakinuma C, Ohnishi S, Ogihara T.

Biochem Biophys Res Commun. 2006 Feb 3;340(1):215-20. Epub 2005 Dec 9.

PMID:
16364247
18.

Establishment of an in vitro high-throughput screening assay for detecting phospholipidosis-inducing potential.

Kasahara T, Tomita K, Murano H, Harada T, Tsubakimoto K, Ogihara T, Ohnishi S, Kakinuma C.

Toxicol Sci. 2006 Mar;90(1):133-41. Epub 2005 Dec 7.

PMID:
16338956
19.

Increased very low density lipoprotein secretion and gonadal fat mass in mice overexpressing liver DGAT1.

Yamazaki T, Sasaki E, Kakinuma C, Yano T, Miura S, Ezaki O.

J Biol Chem. 2005 Jun 3;280(22):21506-14. Epub 2005 Mar 29.

20.

Eisai hyperbilirubinemic rat (EHBR) as an animal model affording high drug-exposure in toxicity studies on organic anions.

Naba H, Kuwayama C, Kakinuma C, Ohnishi S, Ogihara T.

Drug Metab Pharmacokinet. 2004 Oct;19(5):339-51.

21.

Histopathologic difference between chronic pancreatitis animal models and human chronic pancreatitis.

Suda K, Takase M, Fukumura Y, Suzuki F, Jim A, Kakinuma C, Tanaka T, Matsugu Y, Miyasaka K, Funakoshi A.

Pancreas. 2004 Apr;28(3):e86-9.

PMID:
15084989
22.

The gene expression of hepatic proteins responsible for DNA repair and cell proliferation in tamoxifen-induced hepatocarcinogenesis.

Kasahara T, Kuwayama C, Hashiba M, Harada T, Kakinuma C, Miyauchi M, Degawa M.

Cancer Sci. 2003 Jul;94(7):582-8.

23.

Impaired fertility in female mice lacking urinary trypsin inhibitor.

Sato H, Kajikawa S, Kuroda S, Horisawa Y, Nakamura N, Kaga N, Kakinuma C, Kato K, Morishita H, Niwa H, Miyazaki J.

Biochem Biophys Res Commun. 2001 Mar;281(5):1154-60.

PMID:
11243855
24.

Growth-stimulating effect of dienogest, a synthetic steroid, on rodent, canine, and primate mammary glands.

Ishikawa T, Inoue S, Kakinuma C, Kuwayama C, Hamada Y, Shibutani Y.

Toxicology. 2000 Oct 26;151(1-3):91-101.

PMID:
11074304
25.

Acute toxicity of an anti-Fas antibody in mice.

Kakinuma C, Takagaki K, Yatomi T, Nakamura N, Nagata S, Uemura A, Shibutani Y.

Toxicol Pathol. 1999 Jul-Aug;27(4):412-20.

PMID:
10485821
26.

Human natural tumor necrosis factor alpha induces multiple endocrine and hematologic disorders in rats.

Kakinuma C, Hamada Y, Futamura Y, Kuwayama C, Shimoi A, Shibutani Y.

Toxicol Pathol. 1999 Jul-Aug;27(4):402-11.

PMID:
10485820
27.

Plasma cytokine concentrations and splenic changes in cynomolgus monkeys (Macaca fascicularis) with malaria.

Kakinuma C, Futamura Y, Kaga N, Shibutani Y.

Lab Anim Sci. 1999 Feb;49(1):101-4. No abstract available.

PMID:
10090104
28.

Histopathological and biochemical studies on pancreatic fibrosis in WBN/Kob rats.

Kakinuma C, Suda K, Shibutani Y.

Virchows Arch. 1999 Jan;434(1):83-9.

PMID:
10071240
29.

Lipoteichoic acid induces preterm delivery in mice.

Kajikawa S, Kaga N, Futamura Y, Kakinuma C, Shibutani Y.

J Pharmacol Toxicol Methods. 1998 Apr;39(3):147-54.

PMID:
9741389
30.

Trophoblastic apoptosis in mice with preterm delivery and its suppression by urinary trypsin inhibitor.

Kakinuma C, Kuwayama C, Kaga N, Futamura Y, Katsuki Y, Shibutani Y.

Obstet Gynecol. 1997 Jul;90(1):117-24.

PMID:
9207825
31.

Ability of intrauterine bacterial lipopolysaccharide to cause in situ uterine contractions in pregnant rabbits.

Katsuki Y, Kaga N, Kakinuma C, Takagaki K, Kajikawa S, Shibutani Y.

Acta Obstet Gynecol Scand. 1997 Jan;76(1):26-32.

PMID:
9033240
32.

Usefulness of a new tactile sensor for measurement of uterine cervical ripening in mice in a quantitative and noninvasive manner.

Kaga N, Katsuki Y, Kakinuma C, Obata M, Shibutani Y, Omata S.

Am J Obstet Gynecol. 1996 Sep;175(3 Pt 1):713-8.

PMID:
8828439
33.

Spontaneous adrenal and hepatic myelolipomas in the common marmoset.

Kakinuma C, Harada T, Watanabe M, Shibutani Y.

Toxicol Pathol. 1994 Jul-Aug;22(4):440-5.

PMID:
7817133
34.

Successful heterotransplantation of human endometrium in SCID mice.

Aoki D, Katsuki Y, Shimizu A, Kakinuma C, Nozawa S.

Obstet Gynecol. 1994 Feb;83(2):220-8.

PMID:
8290184
35.

[Health care activities in the past 4 years at a village in the outskirts of Matsue City].

Morihiro H, Tomita S, Fujita E, Kakinuma C.

Hokenfu Zasshi. 1980 Mar;36(3):232-40. Japanese. No abstract available.

PMID:
6900770

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