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Items: 28

1.

Efficacy and safety of secukinumab administration by autoinjector in patients with psoriatic arthritis: results from a randomized, placebo-controlled trial (FUTURE 3).

Nash P, Mease PJ, McInnes IB, Rahman P, Ritchlin CT, Blanco R, Dokoupilova E, Andersson M, Kajekar R, Mpofu S, Pricop L; FUTURE 3 study group.

Arthritis Res Ther. 2018 Mar 15;20(1):47. doi: 10.1186/s13075-018-1551-x.

2.

Secukinumab sustains improvement in signs and symptoms of psoriatic arthritis: 2 year results from the phase 3 FUTURE 2 study.

McInnes IB, Mease PJ, Ritchlin CT, Rahman P, Gottlieb AB, Kirkham B, Kajekar R, Delicha EM, Pricop L, Mpofu S.

Rheumatology (Oxford). 2017 Nov 1;56(11):1993-2003. doi: 10.1093/rheumatology/kex301.

3.

Relationship between lung function and quantitative computed tomographic parameters of airway remodeling, air trapping, and emphysema in patients with asthma and chronic obstructive pulmonary disease: A single-center study.

Hartley RA, Barker BL, Newby C, Pakkal M, Baldi S, Kajekar R, Kay R, Laurencin M, Marshall RP, Sousa AR, Parmar H, Siddiqui S, Gupta S, Brightling CE.

J Allergy Clin Immunol. 2016 May;137(5):1413-1422.e12. doi: 10.1016/j.jaci.2016.02.001. Epub 2016 Mar 19.

4.

Identification of inflammatory mediators in patients with Crohn's disease unresponsive to anti-TNFα therapy.

Leal RF, Planell N, Kajekar R, Lozano JJ, Ordás I, Dotti I, Esteller M, Masamunt MC, Parmar H, Ricart E, Panés J, Salas A.

Gut. 2015 Feb;64(2):233-42. doi: 10.1136/gutjnl-2013-306518. Epub 2014 Apr 3.

PMID:
24700437
5.

Clinical significance of small airway obstruction markers in patients with asthma.

Gonem S, Natarajan S, Desai D, Corkill S, Singapuri A, Bradding P, Gustafsson P, Costanza R, Kajekar R, Parmar H, Brightling CE, Siddiqui S.

Clin Exp Allergy. 2014 Apr;44(4):499-507. doi: 10.1111/cea.12257.

PMID:
24341600
6.

Sputum mediator profiling and relationship to airway wall geometry imaging in severe asthma.

Desai D, Gupta S, Siddiqui S, Singapuri A, Monteiro W, Entwisle J, Visvanathan S, Parmar H, Kajekar R, Brightling CE.

Respir Res. 2013 Feb 11;14:17. doi: 10.1186/1465-9921-14-17.

7.

TL1A/TNFSF15 directly induces proinflammatory cytokines, including TNFα, from CD3+CD161+ T cells to exacerbate gut inflammation.

Jin S, Chin J, Seeber S, Niewoehner J, Weiser B, Beaucamp N, Woods J, Murphy C, Fanning A, Shanahan F, Nally K, Kajekar R, Salas A, Planell N, Lozano J, Panes J, Parmar H, DeMartino J, Narula S, Thomas-Karyat DA.

Mucosal Immunol. 2013 Sep;6(5):886-99. doi: 10.1038/mi.2012.124. Epub 2012 Dec 19.

PMID:
23250276
8.

Electrical stimulation of the isolated rat intestine in the presence of nutrient stimulus enhances glucagon-like peptide-1 release.

Schwartz A, Ort T, Kajekar R, Wade PR, Hornby PJ.

Physiol Meas. 2010 Sep;31(9):1147-59. doi: 10.1088/0967-3334/31/9/006. Epub 2010 Jul 28.

PMID:
20664162
9.

TLR3 activation stimulates cytokine secretion without altering agonist-induced human small airway contraction or relaxation.

Cooper PR, Lamb R, Day ND, Branigan PJ, Kajekar R, San Mateo L, Hornby PJ, Panettieri RA Jr.

Am J Physiol Lung Cell Mol Physiol. 2009 Sep;297(3):L530-7. doi: 10.1152/ajplung.00133.2009. Epub 2009 Jun 19.

10.

Calcitonin gene-related peptide affects synaptic and membrane properties of bronchial parasympathetic neurons.

Kajekar R, Myers AC.

Respir Physiol Neurobiol. 2008 Jan 1;160(1):28-36. Epub 2007 Aug 10.

11.

Environmental factors and developmental outcomes in the lung.

Kajekar R.

Pharmacol Ther. 2007 May;114(2):129-45. Epub 2007 Feb 24. Review.

PMID:
17408750
12.

Asthma/allergic airways disease: does postnatal exposure to environmental toxicants promote airway pathobiology?

Plopper CG, Smiley-Jewell SM, Miller LA, Fanucchi MV, Evans MJ, Buckpitt AR, Avdalovic M, Gershwin LJ, Joad JP, Kajekar R, Larson S, Pinkerton KE, Van Winkle LS, Schelegle ES, Pieczarka EM, Wu R, Hyde DM.

Toxicol Pathol. 2007 Jan;35(1):97-110.

PMID:
17325978
13.

Early postnatal exposure to allergen and ozone leads to hyperinnervation of the pulmonary epithelium.

Kajekar R, Pieczarka EM, Smiley-Jewell SM, Schelegle ES, Fanucchi MV, Plopper CG.

Respir Physiol Neurobiol. 2007 Jan 15;155(1):55-63. Epub 2006 Apr 17.

PMID:
16616710
14.

L-arginine supplementation enhances exhaled NO, breath condensate VEGF, and headache at 4,342 m.

Mansoor JK, Morrissey BM, Walby WF, Yoneda KY, Juarez M, Kajekar R, Severinghaus JW, Eldridge MW, Schelegle ES.

High Alt Med Biol. 2005 Winter;6(4):289-300.

PMID:
16351563
15.

Role of cyclooxygenase activation and prostaglandins in antigen-induced excitability changes of bronchial parasympathetic ganglia neurons.

Kajekar R, Undem BJ, Myers AC.

Am J Physiol Lung Cell Mol Physiol. 2003 Apr;284(4):L581-7. Epub 2003 Jan 10.

16.

Endogenous neurokinins facilitate synaptic transmission in guinea pig airway parasympathetic ganglia.

Canning BJ, Reynolds SM, Anukwu LU, Kajekar R, Myers AC.

Am J Physiol Regul Integr Comp Physiol. 2002 Aug;283(2):R320-30.

17.

GABA(A) receptor activation at medullary sympathetic neurons contributes to postexercise hypotension.

Kajekar R, Chen CY, Mutoh T, Bonham AC.

Am J Physiol Heart Circ Physiol. 2002 May;282(5):H1615-24.

18.

Allergic inflammation-induced neuropeptide production in rapidly adapting afferent nerves in guinea pig airways.

Myers AC, Kajekar R, Undem BJ.

Am J Physiol Lung Cell Mol Physiol. 2002 Apr;282(4):L775-81.

19.

The integrative membrane properties of human bronchial parasympathetic Ganglia neurons.

Kajekar R, Rohde HK, Myers AC.

Am J Respir Crit Care Med. 2001 Nov 15;164(10 Pt 1):1927-32.

PMID:
11734448
20.

Neural integration and allergic disease.

Undem BJ, Kajekar R, Hunter DD, Myers AC.

J Allergy Clin Immunol. 2000 Nov;106(5 Suppl):S213-20. Review.

PMID:
11080734
21.

Effect of bradykinin on membrane properties of guinea pig bronchial parasympathetic ganglion neurons.

Kajekar R, Myers AC.

Am J Physiol Lung Cell Mol Physiol. 2000 Mar;278(3):L485-91.

22.

Characterization of vagal afferent subtypes stimulated by bradykinin in guinea pig trachea.

Kajekar R, Proud D, Myers AC, Meeker SN, Undem BJ.

J Pharmacol Exp Ther. 1999 May;289(2):682-7.

PMID:
10215640
23.

Modulation of the release and activity of neuropeptides in the microcirculation.

Brain SD, Newbold P, Kajekar R.

Can J Physiol Pharmacol. 1995 Jul;73(7):995-8.

PMID:
8846443
24.
26.

Pituitary adenylate cyclase activating polypeptide is a potent vasodilator in humans.

Warren JB, Cockcroft JR, Larkin SW, Kajekar R, Macrae A, Ghatei MA, Bloom SR.

J Cardiovasc Pharmacol. 1992 Jul;20(1):83-7.

PMID:
1383635
27.

Pituitary adenylate cyclase activating polypeptide is a potent vasodilator and oedema potentiator in rabbit skin in vivo.

Warren JB, Larkin SW, Coughlan M, Kajekar R, Williams TJ.

Br J Pharmacol. 1992 Jun;106(2):331-4.

28.

Arthropod transmission of AIDS?

Burgess NR, Kajekar RR.

J R Army Med Corps. 1989 Oct;135(3):152-8. No abstract available.

PMID:
2585383

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