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Items: 17

1.

A phase Ib multiple ascending dose study evaluating safety, pharmacokinetics, and early clinical response of brodalumab, a human anti-IL-17R antibody, in methotrexate-resistant rheumatoid arthritis.

Martin DA, Churchill M, Flores-Suarez L, Cardiel MH, Wallace D, Martin R, Phillips K, Kaine JL, Dong H, Salinger D, Stevens E, Russell CB, Chung JB.

Arthritis Res Ther. 2013 Oct 25;15(5):R164. doi: 10.1186/ar4347.

2.
3.

Ocrelizumab, a humanized anti-CD20 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: a phase I/II randomized, blinded, placebo-controlled, dose-ranging study.

Genovese MC, Kaine JL, Lowenstein MB, Del Giudice J, Baldassare A, Schechtman J, Fudman E, Kohen M, Gujrathi S, Trapp RG, Sweiss NJ, Spaniolo G, Dummer W; ACTION Study Group.

Arthritis Rheum. 2008 Sep;58(9):2652-61. doi: 10.1002/art.23732.

4.

Abatacept for the treatment of rheumatoid arthritis: A review.

Kaine JL.

Curr Ther Res Clin Exp. 2007 Nov;68(6):379-99. doi: 10.1016/j.curtheres.2007.12.001.

5.
6.

Efficacy and safety of tacrolimus in patients with rheumatoid arthritis: a double-blind trial.

Yocum DE, Furst DE, Kaine JL, Baldassare AR, Stevenson JT, Borton MA, Mengle-Gaw LJ, Schwartz BD, Wisemandle W, Mekki QA; Tcrolimus Rheumatoid Arthritis Study Group.

Arthritis Rheum. 2003 Dec;48(12):3328-37.

7.

Tacrolimus in rheumatoid arthritis patients receiving concomitant methotrexate: a six-month, open-label study.

Kremer JM, Habros JS, Kolba KS, Kaine JL, Borton MA, Mengle-Gaw LJ, Schwartz BD, Wisemandle W, Mekki QA; Tacrolimus-Methotrexate Rheumatoid Arthritis Study Group.

Arthritis Rheum. 2003 Oct;48(10):2763-8.

8.

Concomitant leflunomide therapy in patients with active rheumatoid arthritis despite stable doses of methotrexate. A randomized, double-blind, placebo-controlled trial.

Kremer JM, Genovese MC, Cannon GW, Caldwell JR, Cush JJ, Furst DE, Luggen ME, Keystone E, Weisman MH, Bensen WM, Kaine JL, Ruderman EM, Coleman P, Curtis DL, Kopp EJ, Kantor SM, Waltuck J, Lindsley HB, Markenson JA, Strand V, Crawford B, Fernando I, Simpson K, Bathon JM.

Ann Intern Med. 2002 Nov 5;137(9):726-33.

PMID:
12416946
9.
10.

Distribution and specificity of nucleotide-reactive autoantibodies in human SLE.

Munns TW, Freeman SK, Liszewski MK, Kaine JL.

J Immunol. 1987 Jul 15;139(2):393-9.

PMID:
3298428
11.

Polymyalgia rheumatica and temporal arteritis: managing older patients.

Pereira M, Kaine JL.

Geriatrics. 1986 Jun;41(6):54-5, 59-60, 63 passim.

PMID:
3710167
12.

Ro (SS-A) antibody and antigen in a patient with congenital complete heart block.

Harley JB, Kaine JL, Fox OF, Reichlin M, Gruber B.

Arthritis Rheum. 1985 Dec;28(12):1321-5.

PMID:
3878714
13.

Detection of human autoantibodies specific for 5'-m7GMP and m7G(5')ppp(5')N.

Munns TW, Liszewski MK, Freeman SK, Kaine JL.

Biochem Biophys Res Commun. 1985 Apr 30;128(2):1014-9.

PMID:
3873239
15.
16.

The kinetics of specific glucocorticoid binding in rat thymus cytosol: evidence for the existence of multiple binding states.

Kaine JL, Nielsen CJ, Pratt WB.

Mol Pharmacol. 1975 Sep;11(5):578-87. No abstract available.

PMID:
1177869
17.

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