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Items: 31


Quantitative Gadolinium-Free Cardiac Fibrosis Imaging in End Stage Renal Disease Patients Reveals A Longitudinal Correlation with Structural and Functional Decline.

Stromp TA, Spear TJ, Holtkamp RM, Andres KN, Kaine JC, Alghuraibawi WH, Leung SW, Fornwalt BK, Vandsburger MH.

Sci Rep. 2018 Nov 19;8(1):16972. doi: 10.1038/s41598-018-35394-4.


A pooled analysis of the safety of tofacitinib as monotherapy or in combination with background conventional synthetic disease-modifying antirheumatic drugs in a Phase 3 rheumatoid arthritis population.

Kivitz AJ, Cohen S, Keystone E, van Vollenhoven RF, Haraoui B, Kaine J, Fan H, Connell CA, Bananis E, Takiya L, Fleischmann R.

Semin Arthritis Rheum. 2018 Dec;48(3):406-415. doi: 10.1016/j.semarthrit.2018.07.006. Epub 2018 Jul 19.


Tofacitinib 5 mg Twice Daily in Patients with Rheumatoid Arthritis and Inadequate Response to Disease-Modifying Antirheumatic Drugs: A Comprehensive Review of Phase 3 Efficacy and Safety.

Bird P, Bensen W, El-Zorkany B, Kaine J, Manapat-Reyes BH, Pascual-Ramos V, Witcombe D, Soma K, Zhang R, Thirunavukkarasu K.

J Clin Rheumatol. 2019 Apr;25(3):115-126. doi: 10.1097/RHU.0000000000000786.


Higher Incidence Rates of Comorbidities in Patients with Psoriatic Arthritis Compared with the General Population Using U.S. Administrative Claims Data.

Kaine J, Song X, Kim G, Hur P, Palmer JB.

J Manag Care Spec Pharm. 2019 Jan;25(1):122-132. doi: 10.18553/jmcp.2018.17421. Epub 2018 Apr 25.


Paramagnetic Resonance of Cobalt(II) Trispyrazolylmethanes and Counterion Association.

Marts AR, Kaine JC, Baum RR, Clayton VL, Bennett JR, Cordonnier LJ, McCarrick R, Hasheminasab A, Crandall LA, Ziegler CJ, Tierney DL.

Inorg Chem. 2017 Jan 3;56(1):618-626. doi: 10.1021/acs.inorgchem.6b02520. Epub 2016 Dec 15.


Long-term safety of subcutaneous abatacept in rheumatoid arthritis: integrated analysis of clinical trial data representing more than four years of treatment.

Alten R, Kaine J, Keystone E, Nash P, Delaet I, Genovese MC.

Arthritis Rheumatol. 2014 Aug;66(8):1987-97. doi: 10.1002/art.38687.


The effects of tocilizumab on osteitis, synovitis and erosion progression in rheumatoid arthritis: results from the ACT-RAY MRI substudy.

Conaghan PG, Peterfy C, Olech E, Kaine J, Ridley D, Dicarlo J, Friedman J, Devenport J, Troum O.

Ann Rheum Dis. 2014 May;73(5):810-6. doi: 10.1136/annrheumdis-2013-204762. Epub 2014 Feb 13.


A phase Ib multiple ascending dose study evaluating safety, pharmacokinetics, and early clinical response of brodalumab, a human anti-IL-17R antibody, in methotrexate-resistant rheumatoid arthritis.

Martin DA, Churchill M, Flores-Suarez L, Cardiel MH, Wallace D, Martin R, Phillips K, Kaine JL, Dong H, Salinger D, Stevens E, Russell CB, Chung JB.

Arthritis Res Ther. 2013 Oct 25;15(5):R164. doi: 10.1186/ar4347.


Evaluation of abatacept administered subcutaneously in adults with active rheumatoid arthritis: impact of withdrawal and reintroduction on immunogenicity, efficacy and safety (phase Iiib ALLOW study).

Kaine J, Gladstein G, Strusberg I, Robles M, Louw I, Gujrathi S, Pappu R, Delaet I, Pans M, Ludivico C.

Ann Rheum Dis. 2012 Jan;71(1):38-44. doi: 10.1136/annrheumdis-2011-200344. Epub 2011 Sep 13.


Ocrelizumab, a humanized anti-CD20 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: a phase I/II randomized, blinded, placebo-controlled, dose-ranging study.

Genovese MC, Kaine JL, Lowenstein MB, Del Giudice J, Baldassare A, Schechtman J, Fudman E, Kohen M, Gujrathi S, Trapp RG, Sweiss NJ, Spaniolo G, Dummer W; ACTION Study Group.

Arthritis Rheum. 2008 Sep;58(9):2652-61. doi: 10.1002/art.23732.


Abatacept for the treatment of rheumatoid arthritis: A review.

Kaine JL.

Curr Ther Res Clin Exp. 2007 Nov;68(6):379-99. doi: 10.1016/j.curtheres.2007.12.001.


Efficacy and safety of tacrolimus in patients with rheumatoid arthritis: a double-blind trial.

Yocum DE, Furst DE, Kaine JL, Baldassare AR, Stevenson JT, Borton MA, Mengle-Gaw LJ, Schwartz BD, Wisemandle W, Mekki QA; Tcrolimus Rheumatoid Arthritis Study Group.

Arthritis Rheum. 2003 Dec;48(12):3328-37.


Tacrolimus in rheumatoid arthritis patients receiving concomitant methotrexate: a six-month, open-label study.

Kremer JM, Habros JS, Kolba KS, Kaine JL, Borton MA, Mengle-Gaw LJ, Schwartz BD, Wisemandle W, Mekki QA; Tacrolimus-Methotrexate Rheumatoid Arthritis Study Group.

Arthritis Rheum. 2003 Oct;48(10):2763-8.


Concomitant leflunomide therapy in patients with active rheumatoid arthritis despite stable doses of methotrexate. A randomized, double-blind, placebo-controlled trial.

Kremer JM, Genovese MC, Cannon GW, Caldwell JR, Cush JJ, Furst DE, Luggen ME, Keystone E, Weisman MH, Bensen WM, Kaine JL, Ruderman EM, Coleman P, Curtis DL, Kopp EJ, Kantor SM, Waltuck J, Lindsley HB, Markenson JA, Strand V, Crawford B, Fernando I, Simpson K, Bathon JM.

Ann Intern Med. 2002 Nov 5;137(9):726-33.


Efficacy of tacrolimus in rheumatoid arthritis patients who have been treated unsuccessfully with methotrexate: a six-month, double-blind, randomized, dose-ranging study.

Furst DE, Saag K, Fleischmann MR, Sherrer Y, Block JA, Schnitzer T, Rutstein J, Baldassare A, Kaine J, Calabrese L, Dietz F, Sack M, Senter RG, Wiesenhutter C, Schiff M, Stein CM, Satoi Y, Matsumoto A, Caldwell J, Harris RE, Moreland LW, Hurd E, Yocum D, Stamler DA.

Arthritis Rheum. 2002 Aug;46(8):2020-8.


Two-year, blinded, randomized, controlled trial of treatment of active rheumatoid arthritis with leflunomide compared with methotrexate. Utilization of Leflunomide in the Treatment of Rheumatoid Arthritis Trial Investigator Group.

Cohen S, Cannon GW, Schiff M, Weaver A, Fox R, Olsen N, Furst D, Sharp J, Moreland L, Caldwell J, Kaine J, Strand V.

Arthritis Rheum. 2001 Sep;44(9):1984-92.


Treatment of elderly patients with nabumetone or diclofenac: gastrointestinal safety profile.

Morgan GJ Jr, Kaine J, DeLapp R, Palmer R.

J Clin Gastroenterol. 2001 Apr;32(4):310-4.


Treatment of active rheumatoid arthritis with leflunomide compared with placebo and methotrexate. Leflunomide Rheumatoid Arthritis Investigators Group.

Strand V, Cohen S, Schiff M, Weaver A, Fleischmann R, Cannon G, Fox R, Moreland L, Olsen N, Furst D, Caldwell J, Kaine J, Sharp J, Hurley F, Loew-Friedrich I.

Arch Intern Med. 1999 Nov 22;159(21):2542-50.


Idiotypic characteristics of immunoglobulins associated with systemic lupus erythematosus. Studies of antibodies deposited in glomeruli of humans.

Kalunian KC, Panosian-Sahakian N, Ebling FM, Cohen AH, Louie JS, Kaine J, Hahn BH.

Arthritis Rheum. 1989 May;32(5):513-22.


Cerebroretinal vasculopathy. A new hereditary syndrome.

Grand MG, Kaine J, Fulling K, Atkinson J, Dowton SB, Farber M, Craver J, Rice K.

Ophthalmology. 1988 May;95(5):649-59.


Distribution and specificity of nucleotide-reactive autoantibodies in human SLE.

Munns TW, Freeman SK, Liszewski MK, Kaine JL.

J Immunol. 1987 Jul 15;139(2):393-9.


Polymyalgia rheumatica and temporal arteritis: managing older patients.

Pereira M, Kaine JL.

Geriatrics. 1986 Jun;41(6):54-5, 59-60, 63 passim.


Ro (SS-A) antibody and antigen in a patient with congenital complete heart block.

Harley JB, Kaine JL, Fox OF, Reichlin M, Gruber B.

Arthritis Rheum. 1985 Dec;28(12):1321-5.


Detection of human autoantibodies specific for 5'-m7GMP and m7G(5')ppp(5')N.

Munns TW, Liszewski MK, Freeman SK, Kaine JL.

Biochem Biophys Res Commun. 1985 Apr 30;128(2):1014-9.


The kinetics of specific glucocorticoid binding in rat thymus cytosol: evidence for the existence of multiple binding states.

Kaine JL, Nielsen CJ, Pratt WB.

Mol Pharmacol. 1975 Sep;11(5):578-87. No abstract available.


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