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Items: 1 to 50 of 85

1.

A Novel Role for GATA3 in Mesangial Cells in Glomerular Development and Injury.

Grigorieva IV, Oszwald A, Grigorieva EF, Schachner H, Neudert B, Ostendorf T, Floege J, Lindenmeyer MT, Cohen CD, Panzer U, Aigner C, Schmidt A, Grosveld F, Thakker RV, Rees AJ, Kain R.

J Am Soc Nephrol. 2019 Aug 12. pii: ASN.2018111143. doi: 10.1681/ASN.2018111143. [Epub ahead of print]

PMID:
31405951
2.

Human DEF6 deficiency underlies an immunodeficiency syndrome with systemic autoimmunity and aberrant CTLA-4 homeostasis.

Serwas NK, Hoeger B, Ardy RC, Stulz SV, Sui Z, Memaran N, Meeths M, Krolo A, Yüce Petronczki Ö, Pfajfer L, Hou TZ, Halliday N, Santos-Valente E, Kalinichenko A, Kennedy A, Mace EM, Mukherjee M, Tesi B, Schrempf A, Loizou JI, Kain R, Bidmon-Fliegenschnee B, Schickel JN, Glauzy S, Huemer J, Garncarz W, Salzer E, Pierides I, Bilic I, Thiel J, Priftakis P, Banerjee PP, Förster-Waldl E, Medgyesi D, Huber WD, Orange JS, Meffre E, Sansom DM, Bryceson YT, Altman A, Boztug K.

Nat Commun. 2019 Jul 15;10(1):3106. doi: 10.1038/s41467-019-10812-x.

3.

Tenascin-C increases lung metastasis by impacting blood vessel invasions.

Sun Z, Velázquez-Quesada I, Murdamoothoo D, Ahowesso C, Yilmaz A, Spenlé C, Averous G, Erne W, Oberndorfer F, Oszwald A, Kain R, Bourdon C, Mangin P, Deligne C, Midwood K, Abou-Faycal C, Lefebvre O, Klein A, van der Heyden M, Chenard MP, Christofori G, Mathelin C, Loustau T, Hussenet T, Orend G.

Matrix Biol. 2019 Jul 6. pii: S0945-053X(19)30128-3. doi: 10.1016/j.matbio.2019.07.001. [Epub ahead of print]

4.

Intrarenal Renin-Angiotensin-System Dysregulation after Kidney Transplantation.

Kovarik JJ, Kaltenecker CC, Kopecky C, Domenig O, Antlanger M, Werzowa J, Eskandary F, Kain R, Poglitsch M, Schmaldienst S, Böhmig GA, Säemann MD.

Sci Rep. 2019 Jul 5;9(1):9762. doi: 10.1038/s41598-019-46114-x.

5.

EXPRESS: Riociguat for the treatment of transthyretin cardiac amyloidosis - Data from a named patient use program in Austria.

Duca F, Aschauer S, Zotter-Tufaro C, Binder C, Kammerlander A, Börries B, Agis H, Kain R, Hengstenberg C, Mascherbauer J, Bonderman D.

Pulm Circ. 2019 Apr 22:2045894019849394. doi: 10.1177/2045894019849394. [Epub ahead of print] No abstract available.

PMID:
31007127
6.

Kidney Injury by Variants in the COL4A5 Gene Aggravated by Polymorphisms in Slit Diaphragm Genes Causes Focal Segmental Glomerulosclerosis.

Frese J, Kettwig M, Zappel H, Hofer J, Gröne HJ, Nagel M, Sunder-Plassmann G, Kain R, Neuweiler J, Gross O.

Int J Mol Sci. 2019 Jan 26;20(3). pii: E519. doi: 10.3390/ijms20030519.

7.

Mechanisms of heart failure in transthyretin vs. light chain amyloidosis.

Binder C, Duca F, Stelzer PD, Nitsche C, Rettl R, Aschauer S, Kammerlander AA, Binder T, Agis H, Kain R, Hengstenberg C, Mascherbauer J, Bonderman D.

Eur Heart J Cardiovasc Imaging. 2019 May 1;20(5):512-524. doi: 10.1093/ehjci/jey225.

PMID:
30649240
8.

Usage Data and Scientific Impact of the Prospectively Established Fluid Bioresources at the Hospital-Based MedUni Wien Biobank.

Haslacher H, Gerner M, Hofer P, Jurkowitsch A, Hainfellner J, Kain R, Wagner OF, Perkmann T.

Biopreserv Biobank. 2018 Oct 18. doi: 10.1089/bio.2018.0032. [Epub ahead of print]

9.

Cardiac Magnetic Resonance T1 Mapping in Cardiac Amyloidosis.

Duca F, Kammerlander AA, Panzenböck A, Binder C, Aschauer S, Loewe C, Agis H, Kain R, Hengstenberg C, Bonderman D, Mascherbauer J.

JACC Cardiovasc Imaging. 2018 Dec;11(12):1924-1926. doi: 10.1016/j.jcmg.2018.06.010. Epub 2018 Aug 15. No abstract available.

PMID:
30121265
10.

Dendritic cells and routing cargo into exosomes.

Leone DA, Rees AJ, Kain R.

Immunol Cell Biol. 2018 May 24. doi: 10.1111/imcb.12170. [Epub ahead of print] Review.

PMID:
29797348
11.

CEBPE-Mutant Specific Granule Deficiency Correlates With Aberrant Granule Organization and Substantial Proteome Alterations in Neutrophils.

Serwas NK, Huemer J, Dieckmann R, Mejstrikova E, Garncarz W, Litzman J, Hoeger B, Zapletal O, Janda A, Bennett KL, Kain R, Kerjaschky D, Boztug K.

Front Immunol. 2018 Mar 29;9:588. doi: 10.3389/fimmu.2018.00588. eCollection 2018.

12.

Lymphatic exosomes promote dendritic cell migration along guidance cues.

Brown M, Johnson LA, Leone DA, Majek P, Vaahtomeri K, Senfter D, Bukosza N, Schachner H, Asfour G, Langer B, Hauschild R, Parapatics K, Hong YK, Bennett KL, Kain R, Detmar M, Sixt M, Jackson DG, Kerjaschki D.

J Cell Biol. 2018 Jun 4;217(6):2205-2221. doi: 10.1083/jcb.201612051. Epub 2018 Apr 12.

13.
14.

Intestinal Failure and Aberrant Lipid Metabolism in Patients With DGAT1 Deficiency.

van Rijn JM, Ardy RC, Kuloğlu Z, Härter B, van Haaften-Visser DY, van der Doef HPJ, van Hoesel M, Kansu A, van Vugt AHM, Thian M, Kokke FTM, Krolo A, Başaran MK, Kaya NG, Aksu AÜ, Dalgıç B, Ozcay F, Baris Z, Kain R, Stigter ECA, Lichtenbelt KD, Massink MPG, Duran KJ, Verheij JBGM, Lugtenberg D, Nikkels PGJ, Brouwer HGF, Verkade HJ, Scheenstra R, Spee B, Nieuwenhuis EES, Coffer PJ, Janecke AR, van Haaften G, Houwen RHJ, Müller T, Middendorp S, Boztug K.

Gastroenterology. 2018 Jul;155(1):130-143.e15. doi: 10.1053/j.gastro.2018.03.040. Epub 2018 Mar 29.

15.

Maternal and Fetal Outcomes of Pregnancies in Women with Atypical Hemolytic Uremic Syndrome.

Gaggl M, Aigner C, Csuka D, Szilágyi Á, Prohászka Z, Kain R, Haninger N, Knechtelsdorfer M, Sunder-Plassmann R, Sunder-Plassmann G, Schmidt A.

J Am Soc Nephrol. 2018 Mar;29(3):1020-1029. doi: 10.1681/ASN.2016090995. Epub 2017 Dec 27.

16.

CD55 Deficiency, Early-Onset Protein-Losing Enteropathy, and Thrombosis.

Ozen A, Comrie WA, Ardy RC, Domínguez Conde C, Dalgic B, Beser ÖF, Morawski AR, Karakoc-Aydiner E, Tutar E, Baris S, Ozcay F, Serwas NK, Zhang Y, Matthews HF, Pittaluga S, Folio LR, Unlusoy Aksu A, McElwee JJ, Krolo A, Kiykim A, Baris Z, Gulsan M, Ogulur I, Snapper SB, Houwen RHJ, Leavis HL, Ertem D, Kain R, Sari S, Erkan T, Su HC, Boztug K, Lenardo MJ.

N Engl J Med. 2017 Jul 6;377(1):52-61. doi: 10.1056/NEJMoa1615887. Epub 2017 Jun 28.

17.

Surface LAMP-2 Is an Endocytic Receptor That Diverts Antigen Internalized by Human Dendritic Cells into Highly Immunogenic Exosomes.

Leone DA, Peschel A, Brown M, Schachner H, Ball MJ, Gyuraszova M, Salzer-Muhar U, Fukuda M, Vizzardelli C, Bohle B, Rees AJ, Kain R.

J Immunol. 2017 Jul 15;199(2):531-546. doi: 10.4049/jimmunol.1601263. Epub 2017 Jun 12.

18.

Digital pathology imaging as a novel platform for standardization and globalization of quantitative nephropathology.

Barisoni L, Gimpel C, Kain R, Laurinavicius A, Bueno G, Zeng C, Liu Z, Schaefer F, Kretzler M, Holzman LB, Hewitt SM.

Clin Kidney J. 2017 Apr;10(2):176-187. doi: 10.1093/ckj/sfw129. Epub 2017 Feb 18.

19.

Cardiac extracellular matrix is associated with adverse outcome in patients with chronic heart failure.

Duca F, Zotter-Tufaro C, Kammerlander AA, Panzenböck A, Aschauer S, Dalos D, Köll B, Börries B, Agis H, Kain R, Aumayr K, Klinglmüller F, Mascherbauer J, Bonderman D.

Eur J Heart Fail. 2017 Apr;19(4):502-511. doi: 10.1002/ejhf.680. Epub 2016 Nov 27.

20.

Histopathology.

Kain R.

Methods Mol Biol. 2017;1508:185-193.

PMID:
27837504
21.

Adhesion of Escherichia coli under flow conditions reveals potential novel effects of FimH mutations.

Feenstra T, Thøgersen MS, Wieser E, Peschel A, Ball MJ, Brandes R, Satchell SC, Stockner T, Aarestrup FM, Rees AJ, Kain R.

Eur J Clin Microbiol Infect Dis. 2017 Mar;36(3):467-478. doi: 10.1007/s10096-016-2820-8. Epub 2016 Nov 5.

22.

Effects of angiotensin-converting-enzyme inhibitor therapy on the regulation of the plasma and cardiac tissue renin-angiotensin system in heart transplant patients.

Kovarik JJ, Kopecky C, Antlanger M, Domenig O, Kaltenecker CC, Werzowa J, Hecking M, Mahr S, Grömmer M, Wallner C, Aumayr K, Kain R, Zuckermann A, Poglitsch M, Säemann MD.

J Heart Lung Transplant. 2017 Mar;36(3):355-365. doi: 10.1016/j.healun.2016.08.022. Epub 2016 Sep 13.

PMID:
27773450
23.

LAMP-2 is required for incorporating syntaxin-17 into autophagosomes and for their fusion with lysosomes.

Hubert V, Peschel A, Langer B, Gröger M, Rees A, Kain R.

Biol Open. 2016 Oct 15;5(10):1516-1529. doi: 10.1242/bio.018648.

24.

Camel bite: An uncommon mode of maxillofacial injury, its mechanism and fatality: Case series and review of literature.

Kain R, Arya S.

Natl J Maxillofac Surg. 2015 Jul-Dec;6(2):172-5. doi: 10.4103/0975-5950.183868.

25.

Amyloid in the heart: an under-recognized threat at the interface of cardiology, haematology, and pathology.

Bonderman D, Agis H, Kain R, Mascherbauer J.

Eur Heart J Cardiovasc Imaging. 2016 Sep;17(9):978-80. doi: 10.1093/ehjci/jew130. Epub 2016 Jul 4. No abstract available.

PMID:
27378771
26.

Parents' Perspective of Quality of Life of Retinoblastoma Survivors.

Batra A, Kain R, Kumari M, Paul R, Dhawan D, Bakhshi S.

Pediatr Blood Cancer. 2016 Jul;63(7):1287-9. doi: 10.1002/pbc.25982. Epub 2016 Apr 1.

PMID:
27038275
27.

The Phenotypic Characterization of the Human Renal Mononuclear Phagocytes Reveal a Co-Ordinated Response to Injury.

Leone DA, Kozakowski N, Kornauth C, Waidacher T, Neudert B, Loeffler AG, Haitel A, Rees AJ, Kain R.

PLoS One. 2016 Mar 21;11(3):e0151674. doi: 10.1371/journal.pone.0151674. eCollection 2016.

28.

Cooperation of ETV6/RUNX1 and BCL2 enhances immunoglobulin production and accelerates glomerulonephritis in transgenic mice.

Bauer E, Schlederer M, Scheicher R, Horvath J, Aigner P, Schiefer AI, Kain R, Regele H, Hoermann G, Steiner G, Kenner L, Sexl V, Villunger A, Moriggl R, Stoiber D.

Oncotarget. 2016 Mar 15;7(11):12191-205. doi: 10.18632/oncotarget.7687.

29.

The germacranolide sesquiterpene lactone neurolenin B of the medicinal plant Neurolaena lobata (L.) R.Br. ex Cass inhibits NPM/ALK-driven cell expansion and NF-κB-driven tumour intravasation.

Unger C, Kiss I, Vasas A, Lajter I, Kramer N, Atanasov AG, Nguyen CH, Chatuphonprasert W, Brenner S, Krieger S, McKinnon R, Peschel A, Kain R, Saiko P, Szekeres T, Kenner L, Hassler MR, Diaz R, Frisch R, Dirsch VM, Jäger W, de Martin R, Bochkov VN, Passreiter CM, Peter-Vörösmarty B, Mader RM, Grusch M, Dolznig H, Kopp B, Zupko I, Hohmann J, Krupitza G.

Phytomedicine. 2015 Aug 15;22(9):862-74. doi: 10.1016/j.phymed.2015.06.003. Epub 2015 Jun 26.

PMID:
26220634
30.

Coming of Age--CC Chemokine Ligand 18 in ANCA-Associated Vasculitis.

Kain R, Rees AJ.

J Am Soc Nephrol. 2015 Sep;26(9):2065-7. doi: 10.1681/ASN.2015020138. Epub 2015 Mar 11. No abstract available.

31.

Lobatin B inhibits NPM/ALK and NF-κB attenuating anaplastic-large-cell-lymphomagenesis and lymphendothelial tumour intravasation.

Kiss I, Unger C, Huu CN, Atanasov AG, Kramer N, Chatruphonprasert W, Brenner S, McKinnon R, Peschel A, Vasas A, Lajter I, Kain R, Saiko P, Szekeres T, Kenner L, Hassler MR, Diaz R, Frisch R, Dirsch VM, Jäger W, de Martin R, Bochkov VN, Passreiter CM, Peter-Vörösmarty B, Mader RM, Grusch M, Dolznig H, Kopp B, Zupko I, Hohmann J, Krupitza G.

Cancer Lett. 2015 Jan 28;356(2 Pt B):994-1006. doi: 10.1016/j.canlet.2014.11.019. Epub 2014 Nov 15.

PMID:
25444930
32.

Redefining genomic privacy: trust and empowerment.

Erlich Y, Williams JB, Glazer D, Yocum K, Farahany N, Olson M, Narayanan A, Stein LD, Witkowski JA, Kain RC.

PLoS Biol. 2014 Nov 4;12(11):e1001983. doi: 10.1371/journal.pbio.1001983. eCollection 2014 Nov.

33.

Long-term outcome of anti-glomerular basement membrane antibody disease treated with immunoadsorption.

Biesenbach P, Kain R, Derfler K, Perkmann T, Soleiman A, Benharkou A, Druml W, Rees A, Säemann MD.

PLoS One. 2014 Jul 31;9(7):e103568. doi: 10.1371/journal.pone.0103568. eCollection 2014.

34.

Widespread vascular inflammation in a patient with antineutrophil cytoplasmic antibody-associated vasculitis as detected by positron emission tomography.

Salomäki SP, Kemppainen J, Aho H, Hohenthal U, Kain R, Koivuviita N, Badeau RM, Seppänen M, Silvoniemi A, Roivainen A, Pirilä L.

Eur J Nucl Med Mol Imaging. 2014 Nov;41(11):2167-8. doi: 10.1007/s00259-014-2847-y. Epub 2014 Jul 18. No abstract available.

PMID:
25034437
35.

Maxillomandibular synostosis misdiagnosed and treated as ankylosis of the temporomandibular joint.

Kain R, Arya S, Sharma U.

Br J Oral Maxillofac Surg. 2014 Sep;52(7):674. doi: 10.1016/j.bjoms.2014.03.024. Epub 2014 May 1. No abstract available.

PMID:
24793414
36.

Autoantibodies to hLAMP-2 in ANCA-negative pauci-immune focal necrotizing GN.

Peschel A, Basu N, Benharkou A, Brandes R, Brown M, Rees AJ, Kain R.

J Am Soc Nephrol. 2014 Mar;25(3):455-63. doi: 10.1681/ASN.2013030320. Epub 2013 Nov 7. Erratum in: J Am Soc Nephrol. 2018 Feb;29(2):704.

37.

A rare case: childhood-onset C3 glomerulonephritis due to homozygous factor H deficiency.

Rusai K, Zaller V, Szilagyi A, Kain R, Prohaszka Z, Cook HT, Aufricht C, Arbeiter K.

CEN Case Rep. 2013 Nov;2(2):234-238. doi: 10.1007/s13730-013-0070-5. Epub 2013 Mar 16.

38.

A single lung transplant in a patient with fabry disease: causality or far-fetched? A case report.

Gaggl M, Kain R, Jaksch P, Haider D, Mundigler G, Voigtländer T, Sunder-Plassmann R, Rommer P, Klepetko W, Sunder-Plassmann G.

Case Rep Transplant. 2013;2013:905743. doi: 10.1155/2013/905743. Epub 2013 Apr 7.

39.

Hereditary amyloidosis caused by R554L fibrinogen Aα-chain mutation in a Spanish family and review of the literature.

Haidinger M, Werzowa J, Kain R, Antlanger M, Hecking M, Pfaffenberger S, Mascherbauer J, Gremmel T, Gilbertson JA, Rowczenio D, Weichhart T, Kopecky C, Hörl WH, Hawkins PN, Säemann MD.

Amyloid. 2013 Jun;20(2):72-9. doi: 10.3109/13506129.2013.781998. Epub 2013 Apr 3.

PMID:
23551149
40.

Focal segmental glomerulosclerosis is induced by microRNA-193a and its downregulation of WT1.

Gebeshuber CA, Kornauth C, Dong L, Sierig R, Seibler J, Reiss M, Tauber S, Bilban M, Wang S, Kain R, Böhmig GA, Moeller MJ, Gröne HJ, Englert C, Martinez J, Kerjaschki D.

Nat Med. 2013 Apr;19(4):481-7. doi: 10.1038/nm.3142. Epub 2013 Mar 17.

PMID:
23502960
41.

L29. Relevance of anti-LAMP-2 in vasculitis: why the controversy.

Kain R.

Presse Med. 2013 Apr;42(4 Pt 2):584-8. doi: 10.1016/j.lpm.2013.01.029. Epub 2013 Feb 28. Review. No abstract available.

PMID:
23453500
42.

B-cell deficiency and severe autoimmunity caused by deficiency of protein kinase C δ.

Salzer E, Santos-Valente E, Klaver S, Ban SA, Emminger W, Prengemann NK, Garncarz W, Müllauer L, Kain R, Boztug H, Heitger A, Arbeiter K, Eitelberger F, Seidel MG, Holter W, Pollak A, Pickl WF, Förster-Waldl E, Boztug K.

Blood. 2013 Apr 18;121(16):3112-6. doi: 10.1182/blood-2012-10-460741. Epub 2013 Jan 14.

43.

What is the evidence for antibodies to LAMP-2 in the pathogenesis of ANCA associated small vessel vasculitis?

Kain R, Rees AJ.

Curr Opin Rheumatol. 2013 Jan;25(1):26-34. doi: 10.1097/BOR.0b013e32835b4f8f. Review.

PMID:
23169102
44.

High prevalence of autoantibodies to hLAMP-2 in anti-neutrophil cytoplasmic antibody-associated vasculitis.

Kain R, Tadema H, McKinney EF, Benharkou A, Brandes R, Peschel A, Hubert V, Feenstra T, Sengölge G, Stegeman C, Heeringa P, Lyons PA, Smith KG, Kallenberg C, Rees AJ.

J Am Soc Nephrol. 2012 Mar;23(3):556-66. doi: 10.1681/ASN.2011090920. Epub 2012 Feb 9.

45.

Anti-hLAMP2-antibodies and dual positivity for anti-GBM and MPO-ANCA in a patient with relapsing pulmonary-renal syndrome.

Etter C, Gaspert A, Regenass S, Wüthrich RP, Kistler T, Kain R, Cohen CD.

BMC Nephrol. 2011 Jun 8;12:26. doi: 10.1186/1471-2369-12-26.

46.

Gross proteinuria and subacute renal failure after coronary angiography - a case report of cholesterol crystal embolization.

Biesenbach P, Gremmel T, Hörl WH, Kain R, Säemann MD.

Wien Klin Wochenschr. 2010 Apr;122(7-8):251-4. doi: 10.1007/s00508-010-1367-4.

PMID:
20503025
47.

Nephrotic syndrome: a watershed in the understanding of membranous nephropathy.

Rees A, Kain R.

Nat Rev Nephrol. 2009 Nov;5(11):617-8. doi: 10.1038/nrneph.2009.167.

PMID:
19855424
48.

Pathogenesis of small vessel vasculitis associated with autoantibodies to neutrophil cytoplasmic antigens: new insights from animal models.

Kain R, Firmin DA, Rees AJ.

Curr Opin Rheumatol. 2010 Jan;22(1):15-20. doi: 10.1097/BOR.0b013e328332c9e4. Review.

PMID:
19823088
49.

Molecular mimicry in pauci-immune focal necrotizing glomerulonephritis.

Kain R, Exner M, Brandes R, Ziebermayr R, Cunningham D, Alderson CA, Davidovits A, Raab I, Jahn R, Ashour O, Spitzauer S, Sunder-Plassmann G, Fukuda M, Klemm P, Rees AJ, Kerjaschki D.

Nat Med. 2008 Oct;14(10):1088-96. doi: 10.1038/nm.1874. Epub 2008 Oct 5.

50.

Kim-1/Tim-1: from biomarker to therapeutic target?

Rees AJ, Kain R.

Nephrol Dial Transplant. 2008 Nov;23(11):3394-6. doi: 10.1093/ndt/gfn480. Epub 2008 Sep 3. No abstract available.

PMID:
18769021

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