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Items: 5


Identifying host regulators and inhibitors of liver stage malaria infection using kinase activity profiles.

Arang N, Kain HS, Glennon EK, Bello T, Dudgeon DR, Walter ENF, Gujral TS, Kaushansky A.

Nat Commun. 2017 Nov 1;8(1):1232. doi: 10.1038/s41467-017-01345-2.


Complete attenuation of genetically engineered Plasmodium falciparum sporozoites in human subjects.

Kublin JG, Mikolajczak SA, Sack BK, Fishbaugher ME, Seilie A, Shelton L, VonGoedert T, Firat M, Magee S, Fritzen E, Betz W, Kain HS, Dankwa DA, Steel RW, Vaughan AM, Noah Sather D, Murphy SC, Kappe SH.

Sci Transl Med. 2017 Jan 4;9(371). pii: eaad9099. doi: 10.1126/scitranslmed.aad9099.


Malaria parasites target the hepatocyte receptor EphA2 for successful host infection.

Kaushansky A, Douglass AN, Arang N, Vigdorovich V, Dambrauskas N, Kain HS, Austin LS, Sather DN, Kappe SH.

Science. 2015 Nov 27;350(6264):1089-92. doi: 10.1126/science.aad3318.


Host-based Prophylaxis Successfully Targets Liver Stage Malaria Parasites.

Douglass AN, Kain HS, Abdullahi M, Arang N, Austin LS, Mikolajczak SA, Billman ZP, Hume JCC, Murphy SC, Kappe SHI, Kaushansky A.

Mol Ther. 2015 May;23(5):857-865. doi: 10.1038/mt.2015.18. Epub 2015 Feb 4.


Malaria parasite liver stages render host hepatocytes susceptible to mitochondria-initiated apoptosis.

Kaushansky A, Metzger PG, Douglass AN, Mikolajczak SA, Lakshmanan V, Kain HS, Kappe SH.

Cell Death Dis. 2013 Aug 8;4:e762. doi: 10.1038/cddis.2013.286.

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