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Items: 28


Isolation and In Vitro Culture of Human Gut Progenitor Cells.

Bruce J, Kaiko GE, Keely S.

Methods Mol Biol. 2019;2029:49-62. doi: 10.1007/978-1-4939-9631-5_5.


IL-22 and its receptors are increased in human and experimental COPD and contribute to pathogenesis.

Starkey MR, Plank MW, Casolari P, Papi A, Pavlidis S, Guo Y, Cameron GJM, Haw TJ, Tam A, Obiedat M, Donovan C, Hansbro NG, Nguyen DH, Nair PM, Kim RY, Horvat JC, Kaiko GE, Durum SK, Wark PA, Sin DD, Caramori G, Adcock IM, Foster PS, Hansbro PM.

Eur Respir J. 2019 Jul 18;54(1). pii: 1800174. doi: 10.1183/13993003.00174-2018. Print 2019 Jul.


PAI-1 augments mucosal damage in colitis.

Kaiko GE, Chen F, Lai CW, Chiang IL, Perrigoue J, Stojmirovi─ç A, Li K, Muegge BD, Jain U, VanDussen KL, Goggins BJ, Keely S, Weaver J, Foster PS, Lawrence DA, Liu TC, Stappenbeck TS.

Sci Transl Med. 2019 Mar 6;11(482). pii: eaat0852. doi: 10.1126/scitranslmed.aat0852.


Cellular differentiation: Potential insight into butyrate paradox?

Ryu SH, Kaiko GE, Stappenbeck TS.

Mol Cell Oncol. 2018 Feb 27;5(3):e1212685. doi: 10.1080/23723556.2016.1212685. eCollection 2018.


Interaction between smoking and ATG16L1T300A triggers Paneth cell defects in Crohn's disease.

Liu TC, Kern JT, VanDussen KL, Xiong S, Kaiko GE, Wilen CB, Rajala MW, Caruso R, Holtzman MJ, Gao F, McGovern DP, Nunez G, Head RD, Stappenbeck TS.

J Clin Invest. 2018 Nov 1;128(11):5110-5122. doi: 10.1172/JCI120453. Epub 2018 Oct 15.


Developments in cystic fibrosis personalised epithelial assays: Science and patient perspectives.

Kaiko GE, Wark PAB.

J Cyst Fibros. 2018 May;17(3):289-291. doi: 10.1016/j.jcf.2018.03.012. Epub 2018 Apr 13. No abstract available.


The microbial metabolite desaminotyrosine protects from influenza through type I interferon.

Steed AL, Christophi GP, Kaiko GE, Sun L, Goodwin VM, Jain U, Esaulova E, Artyomov MN, Morales DJ, Holtzman MJ, Boon ACM, Lenschow DJ, Stappenbeck TS.

Science. 2017 Aug 4;357(6350):498-502. doi: 10.1126/science.aam5336.


Modeling TH 2 responses and airway inflammation to understand fundamental mechanisms regulating the pathogenesis of asthma.

Foster PS, Maltby S, Rosenberg HF, Tay HL, Hogan SP, Collison AM, Yang M, Kaiko GE, Hansbro PM, Kumar RK, Mattes J.

Immunol Rev. 2017 Jul;278(1):20-40. doi: 10.1111/imr.12549. Review.


Th22 Cells Form a Distinct Th Lineage from Th17 Cells In Vitro with Unique Transcriptional Properties and Tbet-Dependent Th1 Plasticity.

Plank MW, Kaiko GE, Maltby S, Weaver J, Tay HL, Shen W, Wilson MS, Durum SK, Foster PS.

J Immunol. 2017 Mar 1;198(5):2182-2190. doi: 10.4049/jimmunol.1601480. Epub 2017 Jan 18.


Harnessing TGF-╬▓ and BMP signaling for expansion of p63-positive epithelial stem cells.

Brody SL, Kaiko GE.

Stem Cell Investig. 2016 Nov 15;3:82. doi: 10.21037/sci.2016.10.13. eCollection 2016. No abstract available.


The Colonic Crypt Protects Stem Cells from Microbiota-Derived Metabolites.

Kaiko GE, Ryu SH, Koues OI, Collins PL, Solnica-Krezel L, Pearce EJ, Pearce EL, Oltz EM, Stappenbeck TS.

Cell. 2016 Nov 3;167(4):1137. doi: 10.1016/j.cell.2016.10.034. No abstract available.


The Colonic Crypt Protects Stem Cells from Microbiota-Derived Metabolites.

Kaiko GE, Ryu SH, Koues OI, Collins PL, Solnica-Krezel L, Pearce EJ, Pearce EL, Oltz EM, Stappenbeck TS.

Cell. 2016 Jun 16;165(7):1708-1720. doi: 10.1016/j.cell.2016.05.018. Epub 2016 Jun 2. Erratum in: Cell. 2016 Nov 3;167(4):1137.


Correction: Antagonism of miR-328 Increases the Antimicrobial Function of Macrophages and Neutrophils and Rapid Clearance of Non-typeable Haemophilus Influenzae (NTHi) from Infected Lung.

Tay HL, Kaiko GE, Plank M, Li J, Maltby S, Essilfie AT, Jarnicki A, Yang M, Mattes J, Hansbro PM, Foster PS.

PLoS Pathog. 2015 Jun 24;11(6):e1004956. doi: 10.1371/journal.ppat.1004956. eCollection 2015 Jun.


Colitogenic Bacteroides thetaiotaomicron Antigens Access Host Immune Cells in a Sulfatase-Dependent Manner via Outer Membrane Vesicles.

Hickey CA, Kuhn KA, Donermeyer DL, Porter NT, Jin C, Cameron EA, Jung H, Kaiko GE, Wegorzewska M, Malvin NP, Glowacki RW, Hansson GC, Allen PM, Martens EC, Stappenbeck TS.

Cell Host Microbe. 2015 May 13;17(5):672-80. doi: 10.1016/j.chom.2015.04.002.


Antagonism of miR-328 increases the antimicrobial function of macrophages and neutrophils and rapid clearance of non-typeable Haemophilus influenzae (NTHi) from infected lung.

Tay HL, Kaiko GE, Plank M, Li J, Maltby S, Essilfie AT, Jarnicki A, Yang M, Mattes J, Hansbro PM, Foster PS.

PLoS Pathog. 2015 Apr 20;11(4):e1004549. doi: 10.1371/journal.ppat.1004549. eCollection 2015 Apr. Erratum in: PLoS Pathog. 2015 Jun;11(6):e1004956.


Host-microbe interactions shaping the gastrointestinal environment.

Kaiko GE, Stappenbeck TS.

Trends Immunol. 2014 Nov;35(11):538-48. doi: 10.1016/ Epub 2014 Sep 11. Review.


Toll-like receptor 7 gene deficiency and early-life Pneumovirus infection interact to predispose toward the development of asthma-like pathology in mice.

Kaiko GE, Loh Z, Spann K, Lynch JP, Lalwani A, Zheng Z, Davidson S, Uematsu S, Akira S, Hayball J, Diener KR, Baines KJ, Simpson JL, Foster PS, Phipps S.

J Allergy Clin Immunol. 2013 May;131(5):1331-9.e10. doi: 10.1016/j.jaci.2013.02.041. Epub 2013 Apr 2.


The emerging role of microRNAs in regulating immune and inflammatory responses in the lung.

Foster PS, Plank M, Collison A, Tay HL, Kaiko GE, Li J, Johnston SL, Hansbro PM, Kumar RK, Yang M, Mattes J.

Immunol Rev. 2013 May;253(1):198-215. doi: 10.1111/imr.12058. Review.


Th2 cytokine antagonists: potential treatments for severe asthma.

Hansbro PM, Scott GV, Essilfie AT, Kim RY, Starkey MR, Nguyen DH, Allen PD, Kaiko GE, Yang M, Horvat JC, Foster PS.

Expert Opin Investig Drugs. 2013 Jan;22(1):49-69. doi: 10.1517/13543784.2013.732997. Epub 2012 Nov 5. Review.


Interleukin-13 promotes susceptibility to chlamydial infection of the respiratory and genital tracts.

Asquith KL, Horvat JC, Kaiko GE, Carey AJ, Beagley KW, Hansbro PM, Foster PS.

PLoS Pathog. 2011 May;7(5):e1001339. doi: 10.1371/journal.ppat.1001339. Epub 2011 May 5.


Cytokine/anti-cytokine therapy - novel treatments for asthma?

Hansbro PM, Kaiko GE, Foster PS.

Br J Pharmacol. 2011 May;163(1):81-95. doi: 10.1111/j.1476-5381.2011.01219.x. Review.


Responses of airway epithelium to environmental injury: role in the induction phase of childhood asthma.

Kumar RK, Siegle JS, Kaiko GE, Herbert C, Mattes JE, Foster PS.

J Allergy (Cairo). 2011;2011:257017. doi: 10.1155/2011/257017. Epub 2011 Nov 1.


New insights into the generation of Th2 immunity and potential therapeutic targets for the treatment of asthma.

Kaiko GE, Foster PS.

Curr Opin Allergy Clin Immunol. 2011 Feb;11(1):39-45. doi: 10.1097/ACI.0b013e328342322f. Review.


NK cell deficiency predisposes to viral-induced Th2-type allergic inflammation via epithelial-derived IL-25.

Kaiko GE, Phipps S, Angkasekwinai P, Dong C, Foster PS.

J Immunol. 2010 Oct 15;185(8):4681-90. doi: 10.4049/jimmunol.1001758. Epub 2010 Sep 20.


Toll/IL-1 signaling is critical for house dust mite-specific helper T cell type 2 and type 17 [corrected] responses.

Phipps S, Lam CE, Kaiko GE, Foo SY, Collison A, Mattes J, Barry J, Davidson S, Oreo K, Smith L, Mansell A, Matthaei KI, Foster PS.

Am J Respir Crit Care Med. 2009 May 15;179(10):883-93. doi: 10.1164/rccm.200806-974OC. Epub 2009 Feb 26. Erratum in: Am J Respir Crit Care Med. 2009 Nov 15;180(10):1032.


Chlamydia muridarum infection subverts dendritic cell function to promote Th2 immunity and airways hyperreactivity.

Kaiko GE, Phipps S, Hickey DK, Lam CE, Hansbro PM, Foster PS, Beagley KW.

J Immunol. 2008 Feb 15;180(4):2225-32.


Immunological decision-making: how does the immune system decide to mount a helper T-cell response?

Kaiko GE, Horvat JC, Beagley KW, Hansbro PM.

Immunology. 2008 Mar;123(3):326-38. Epub 2007 Nov 5. Review.


Neonatal chlamydial infection induces mixed T-cell responses that drive allergic airway disease.

Horvat JC, Beagley KW, Wade MA, Preston JA, Hansbro NG, Hickey DK, Kaiko GE, Gibson PG, Foster PS, Hansbro PM.

Am J Respir Crit Care Med. 2007 Sep 15;176(6):556-64. Epub 2007 Jun 28.


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