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Items: 1 to 50 of 483

1.

Protein Kinase N Promotes Stress-Induced Cardiac Dysfunction Through Phosphorylation of Myocardin-Related Transcription Factor A and Disruption of its Interaction with Actin.

Sakaguchi T, Takefuji M, Wettschureck N, Hamaguchi T, Amano M, Kato K, Tsuda T, Eguchi S, Ishihama S, Mori Y, Yura Y, Yoshida T, Unno K, Okumura T, Ishii H, Shimizu Y, Bando YK, Ohashi K, Ouchi N, Enomoto A, Offermanns S, Kaibuchi K, Murohara T.

Circulation. 2019 Sep 30. doi: 10.1161/CIRCULATIONAHA.119.041019. [Epub ahead of print]

PMID:
31564129
2.

Phosphorylation of gephyrin in zebrafish Mauthner cells governs glycine receptor clustering and behavioral desensitization to sound.

Ogino K, Yamada K, Nishioka T, Oda Y, Kaibuchi K, Hirata H.

J Neurosci. 2019 Sep 26. pii: 1315-19. doi: 10.1523/JNEUROSCI.1315-19.2019. [Epub ahead of print]

PMID:
31558619
3.

Pathological Progression Induced by the Frontotemporal Dementia-Associated R406W Tau Mutation in Patient-Derived iPSCs.

Nakamura M, Shiozawa S, Tsuboi D, Amano M, Watanabe H, Maeda S, Kimura T, Yoshimatsu S, Kisa F, Karch CM, Miyasaka T, Takashima A, Sahara N, Hisanaga SI, Ikeuchi T, Kaibuchi K, Okano H.

Stem Cell Reports. 2019 Oct 8;13(4):684-699. doi: 10.1016/j.stemcr.2019.08.011. Epub 2019 Sep 19.

4.

GDP-Bound Rab27a Dissociates from the Endocytic Machinery in a Phosphorylation-Dependent Manner after Insulin Secretion.

Kimura T, Yamaoka M, Terabayashi T, Kaibuchi K, Ishikawa T, Ishizaki T.

Biol Pharm Bull. 2019;42(9):1532-1537. doi: 10.1248/bpb.b19-00242.

5.

IRR is involved in glucose-induced endocytosis after insulin secretion.

Yamaoka M, Terabayashi T, Nishioka T, Kaibuchi K, Ishikawa T, Ishizaki T, Kimura T.

J Pharmacol Sci. 2019 Jul;140(3):300-304. doi: 10.1016/j.jphs.2019.07.002. Epub 2019 Jul 5.

6.

Hyaluronan synthesis supports glutamate transporter activity.

Hayashi MK, Nishioka T, Shimizu H, Takahashi K, Kakegawa W, Mikami T, Hirayama Y, Koizumi S, Yoshida S, Yuzaki M, Tammi M, Sekino Y, Kaibuchi K, Shigemoto-Mogami Y, Yasui M, Sato K.

J Neurochem. 2019 Aug;150(3):249-263. doi: 10.1111/jnc.14791. Epub 2019 Jul 9.

PMID:
31188471
7.

LRRK1 phosphorylation of Rab7 at S72 links trafficking of EGFR-containing endosomes to its effector RILP.

Hanafusa H, Yagi T, Ikeda H, Hisamoto N, Nishioka T, Kaibuchi K, Shirakabe K, Matsumoto K.

J Cell Sci. 2019 Jun 3;132(11). pii: jcs228809. doi: 10.1242/jcs.228809.

PMID:
31085713
8.

Neuronal Polarity: Positive and Negative Feedback Signals.

Takano T, Funahashi Y, Kaibuchi K.

Front Cell Dev Biol. 2019 Apr 24;7:69. doi: 10.3389/fcell.2019.00069. eCollection 2019.

9.

In Vivo Identification of Protein Kinase Substrates by Kinase-Oriented Substrate Screening (KIOSS).

Nishioka T, Amano M, Funahashi Y, Tsuboi D, Yamahashi Y, Kaibuchi K.

Curr Protoc Chem Biol. 2019 Mar;11(1):e60. doi: 10.1002/cpch.60. Epub 2019 Jan 7.

PMID:
30615307
10.

Comprehensive analysis of kinase-oriented phospho-signalling pathways.

Amano M, Nishioka T, Tsuboi D, Kuroda K, Funahashi Y, Yamahashi Y, Kaibuchi K.

J Biochem. 2019 Apr 1;165(4):301-307. doi: 10.1093/jb/mvy115. Review.

PMID:
30590682
11.

Balance between dopamine and adenosine signals regulates the PKA/Rap1 pathway in striatal medium spiny neurons.

Zhang X, Nagai T, Ahammad RU, Kuroda K, Nakamuta S, Nakano T, Yukinawa N, Funahashi Y, Yamahashi Y, Amano M, Yoshimoto J, Yamada K, Kaibuchi K.

Neurochem Int. 2019 Jan;122:8-18. doi: 10.1016/j.neuint.2018.10.008. Epub 2018 Oct 15.

12.

Cell type-specific activation of mitogen-activated protein kinase in D1 receptor-expressing neurons of the nucleus accumbens potentiates stimulus-reward learning in mice.

Bin Saifullah MA, Nagai T, Kuroda K, Wulaer B, Nabeshima T, Kaibuchi K, Yamada K.

Sci Rep. 2018 Sep 26;8(1):14413. doi: 10.1038/s41598-018-32840-1.

13.

Repetitive and compulsive-like behaviors lead to cognitive dysfunction in Disc1Δ2-3/Δ2-3 mice.

Wulaer B, Nagai T, Sobue A, Itoh N, Kuroda K, Kaibuchi K, Nabeshima T, Yamada K.

Genes Brain Behav. 2018 Nov;17(8):e12478. doi: 10.1111/gbb.12478. Epub 2018 Apr 30.

PMID:
29635888
14.

Targeting Tyro3 ameliorates a model of PGRN-mutant FTLD-TDP via tau-mediated synaptic pathology.

Fujita K, Chen X, Homma H, Tagawa K, Amano M, Saito A, Imoto S, Akatsu H, Hashizume Y, Kaibuchi K, Miyano S, Okazawa H.

Nat Commun. 2018 Jan 30;9(1):433. doi: 10.1038/s41467-018-02821-z.

15.

Meis1 Coordinates Cerebellar Granule Cell Development by Regulating Pax6 Transcription, BMP Signaling and Atoh1 Degradation.

Owa T, Taya S, Miyashita S, Yamashita M, Adachi T, Yamada K, Yokoyama M, Aida S, Nishioka T, Inoue YU, Goitsuka R, Nakamura T, Inoue T, Kaibuchi K, Hoshino M.

J Neurosci. 2018 Jan 31;38(5):1277-1294. doi: 10.1523/JNEUROSCI.1545-17.2017. Epub 2018 Jan 9.

16.

Valosin-containing protein (VCP) is a novel IQ motif-containing GTPase activating protein 1 (IQGAP1)-interacting protein.

Itoh N, Nagai T, Watanabe T, Taki K, Nabeshima T, Kaibuchi K, Yamada K.

Biochem Biophys Res Commun. 2017 Dec 2;493(4):1384-1389. doi: 10.1016/j.bbrc.2017.09.159. Epub 2017 Sep 29.

PMID:
28970065
17.

Daple Coordinates Planar Polarized Microtubule Dynamics in Ependymal Cells and Contributes to Hydrocephalus.

Takagishi M, Sawada M, Ohata S, Asai N, Enomoto A, Takahashi K, Weng L, Ushida K, Ara H, Matsui S, Kaibuchi K, Sawamoto K, Takahashi M.

Cell Rep. 2017 Jul 25;20(4):960-972. doi: 10.1016/j.celrep.2017.06.089.

18.

Discovery of long-range inhibitory signaling to ensure single axon formation.

Takano T, Wu M, Nakamuta S, Naoki H, Ishizawa N, Namba T, Watanabe T, Xu C, Hamaguchi T, Yura Y, Amano M, Hahn KM, Kaibuchi K.

Nat Commun. 2017 Jun 26;8(1):33. doi: 10.1038/s41467-017-00044-2.

19.

Phospholipid localization implies microglial morphology and function via Cdc42 in vitro.

Tokizane K, Konishi H, Makide K, Kawana H, Nakamuta S, Kaibuchi K, Ohwada T, Aoki J, Kiyama H.

Glia. 2017 May;65(5):740-755. doi: 10.1002/glia.23123. Epub 2017 Feb 9.

PMID:
28181299
20.

Neuropeptide Y neuronal network dysfunction in the frontal lobe of a genetic mouse model of schizophrenia.

Morosawa S, Iritani S, Fujishiro H, Sekiguchi H, Torii Y, Habuchi C, Kuroda K, Kaibuchi K, Ozaki N.

Neuropeptides. 2017 Apr;62:27-35. doi: 10.1016/j.npep.2016.12.010. Epub 2017 Jan 5.

PMID:
28073591
21.

Reward signals downstream of dopamine D1 receptors.

Nagai T, Yamada K, Kaibuchi K.

Nihon Arukoru Yakubutsu Igakkai Zasshi. 2016 Dec;51(6):371-381. Review. English, Japanese.

PMID:
30461245
22.

A FRET Biosensor for ROCK Based on a Consensus Substrate Sequence Identified by KISS Technology.

Li C, Imanishi A, Komatsu N, Terai K, Amano M, Kaibuchi K, Matsuda M.

Cell Struct Funct. 2017 Jan 11;42(1):1-13. doi: 10.1247/csf.16016. Epub 2016 Nov 23.

23.

Immunohistochemical evaluation of the GABAergic neuronal system in the prefrontal cortex of a DISC1 knockout mouse model of schizophrenia.

Umeda K, Iritani S, Fujishiro H, Sekiguchi H, Torii Y, Habuchi C, Kuroda K, Kaibuchi K, Ozaki N.

Synapse. 2016 Dec;70(12):508-518. doi: 10.1002/syn.21924. Epub 2016 Aug 1.

PMID:
27421906
24.

Tomosyn Negatively Regulates Arginine Vasopressin Secretion in Embryonic Stem Cell-Derived Neurons.

Takeuchi S, Iwama S, Takagi H, Kiyota A, Nakashima K, Izumida H, Fujisawa H, Iwata N, Suga H, Watanabe T, Kaibuchi K, Oiso Y, Arima H, Sugimura Y.

PLoS One. 2016 Oct 12;11(10):e0164544. doi: 10.1371/journal.pone.0164544. eCollection 2016.

25.

A new approach for the direct visualization of the membrane cytoskeleton in cryo-electron microscopy: a comparative study with freeze-etching electron microscopy.

Makihara M, Watanabe T, Usukura E, Kaibuchi K, Narita A, Tanaka N, Usukura J.

Microscopy (Oxf). 2016 Dec;65(6):488-498. Epub 2016 Sep 1.

PMID:
27587510
26.

Identification of Protein Kinase Substrates by the Kinase-Interacting Substrate Screening (KISS) Approach.

Amano M, Nishioka T, Yura Y, Kaibuchi K.

Curr Protoc Cell Biol. 2016 Sep 1;72:14.16.1-14.16.12. doi: 10.1002/cpcb.8.

PMID:
27580705
27.

Phosphorylation Signals in Striatal Medium Spiny Neurons.

Nagai T, Yoshimoto J, Kannon T, Kuroda K, Kaibuchi K.

Trends Pharmacol Sci. 2016 Oct;37(10):858-871. doi: 10.1016/j.tips.2016.07.003. Epub 2016 Aug 18. Review.

PMID:
27546785
28.

NMDA receptor antagonist prevents cell death in the hippocampal dentate gyrus induced by hyponatremia accompanying adrenal insufficiency in rats.

Izumida H, Takagi H, Fujisawa H, Iwata N, Nakashima K, Takeuchi S, Iwama S, Namba T, Komatu Y, Kaibuchi K, Oiso Y, Arima H, Sugimura Y.

Exp Neurol. 2017 Jan;287(Pt 1):65-74. doi: 10.1016/j.expneurol.2016.08.007. Epub 2016 Aug 12.

PMID:
27527984
29.

Survival of corticostriatal neurons by Rho/Rho-kinase signaling pathway.

Kobayashi K, Sano H, Kato S, Kuroda K, Nakamuta S, Isa T, Nambu A, Kaibuchi K, Kobayashi K.

Neurosci Lett. 2016 Sep 6;630:45-52. doi: 10.1016/j.neulet.2016.07.020. Epub 2016 Jul 15.

PMID:
27424794
30.

Stimulation of Synaptic Vesicle Exocytosis by the Mental Disease Gene DISC1 is Mediated by N-Type Voltage-Gated Calcium Channels.

Tang W, Thevathasan JV, Lin Q, Lim KB, Kuroda K, Kaibuchi K, Bilger M, Soong TW, Fivaz M.

Front Synaptic Neurosci. 2016 Jun 14;8:15. doi: 10.3389/fnsyn.2016.00015. eCollection 2016.

31.

Focused Proteomics Revealed a Novel Rho-kinase Signaling Pathway in the Heart.

Yura Y, Amano M, Takefuji M, Bando T, Suzuki K, Kato K, Hamaguchi T, Hasanuzzaman Shohag M, Takano T, Funahashi Y, Nakamuta S, Kuroda K, Nishioka T, Murohara T, Kaibuchi K.

Cell Struct Funct. 2016 Aug 23;41(2):105-20. doi: 10.1247/csf.16011. Epub 2016 Jun 23.

32.

PAR3-aPKC regulates Tiam1 by modulating suppressive internal interactions.

Matsuzawa K, Akita H, Watanabe T, Kakeno M, Matsui T, Wang S, Kaibuchi K.

Mol Biol Cell. 2016 May 1;27(9):1511-23. doi: 10.1091/mbc.E15-09-0670. Epub 2016 Mar 3.

33.

Phosphoproteomics of the Dopamine Pathway Enables Discovery of Rap1 Activation as a Reward Signal In Vivo.

Nagai T, Nakamuta S, Kuroda K, Nakauchi S, Nishioka T, Takano T, Zhang X, Tsuboi D, Funahashi Y, Nakano T, Yoshimoto J, Kobayashi K, Uchigashima M, Watanabe M, Miura M, Nishi A, Kobayashi K, Yamada K, Amano M, Kaibuchi K.

Neuron. 2016 Feb 3;89(3):550-65. doi: 10.1016/j.neuron.2015.12.019. Epub 2016 Jan 21.

34.

Single-Cell Memory Regulates a Neural Circuit for Sensory Behavior.

Kobayashi K, Nakano S, Amano M, Tsuboi D, Nishioka T, Ikeda S, Yokoyama G, Kaibuchi K, Mori I.

Cell Rep. 2016 Jan 5;14(1):11-21. doi: 10.1016/j.celrep.2015.11.064. Epub 2015 Dec 24.

35.

PI3K regulates endocytosis after insulin secretion by mediating signaling crosstalk between Arf6 and Rab27a.

Yamaoka M, Ando T, Terabayashi T, Okamoto M, Takei M, Nishioka T, Kaibuchi K, Matsunaga K, Ishizaki R, Izumi T, Niki I, Ishizaki T, Kimura T.

J Cell Sci. 2016 Feb 1;129(3):637-49. doi: 10.1242/jcs.180141. Epub 2015 Dec 18.

36.

A CDC42EP4/septin-based perisynaptic glial scaffold facilitates glutamate clearance.

Ageta-Ishihara N, Yamazaki M, Konno K, Nakayama H, Abe M, Hashimoto K, Nishioka T, Kaibuchi K, Hattori S, Miyakawa T, Tanaka K, Huda F, Hirai H, Hashimoto K, Watanabe M, Sakimura K, Kinoshita M.

Nat Commun. 2015 Dec 10;6:10090. doi: 10.1038/ncomms10090.

37.

Role for Daple in non-canonical Wnt signaling during gastric cancer invasion and metastasis.

Ara H, Takagishi M, Enomoto A, Asai M, Ushida K, Asai N, Shimoyama Y, Kaibuchi K, Kodera Y, Takahashi M.

Cancer Sci. 2016 Feb;107(2):133-9. doi: 10.1111/cas.12848. Epub 2015 Dec 23.

38.

Radial Glial Cell-Neuron Interaction Directs Axon Formation at the Opposite Side of the Neuron from the Contact Site.

Xu C, Funahashi Y, Watanabe T, Takano T, Nakamuta S, Namba T, Kaibuchi K.

J Neurosci. 2015 Oct 28;35(43):14517-32. doi: 10.1523/JNEUROSCI.1266-15.2015.

39.

Regulation of neuronal migration, an emerging topic in autism spectrum disorders.

Reiner O, Karzbrun E, Kshirsagar A, Kaibuchi K.

J Neurochem. 2016 Feb;136(3):440-56. doi: 10.1111/jnc.13403. Epub 2015 Nov 13. Review.

40.

Catecholaminergic neuronal network dysfunction in the frontal lobe of a genetic mouse model of schizophrenia.

Iritani S, Sekiguchi H, Habuchi C, Torii Y, Kuroda K, Kaibuchi K, Ozaki N.

Acta Neuropsychiatr. 2016 Apr;28(2):117-23. doi: 10.1017/neu.2015.51. Epub 2015 Sep 3.

PMID:
26333915
41.

TTBK2 with EB1/3 regulates microtubule dynamics in migrating cells through KIF2A phosphorylation.

Watanabe T, Kakeno M, Matsui T, Sugiyama I, Arimura N, Matsuzawa K, Shirahige A, Ishidate F, Nishioka T, Taya S, Hoshino M, Kaibuchi K.

J Cell Biol. 2015 Aug 31;210(5):737-51. doi: 10.1083/jcb.201412075.

42.

Extracellular and Intracellular Signaling for Neuronal Polarity.

Namba T, Funahashi Y, Nakamuta S, Xu C, Takano T, Kaibuchi K.

Physiol Rev. 2015 Jul;95(3):995-1024. doi: 10.1152/physrev.00025.2014. Review.

43.

Phosphoproteomic Analysis Using the WW and FHA Domains as Biological Filters.

Shohag MH, Nishioka T, Ahammad RU, Nakamuta S, Yura Y, Hamaguchi T, Kaibuchi K, Amano M.

Cell Struct Funct. 2015;40(2):95-104. doi: 10.1247/csf.15004. Epub 2015 Jun 27.

44.

Kinase-interacting substrate screening is a novel method to identify kinase substrates.

Amano M, Hamaguchi T, Shohag MH, Kozawa K, Kato K, Zhang X, Yura Y, Matsuura Y, Kataoka C, Nishioka T, Kaibuchi K.

J Cell Biol. 2015 Jun 22;209(6):895-912. doi: 10.1083/jcb.201412008.

45.

Neuronal polarization.

Takano T, Xu C, Funahashi Y, Namba T, Kaibuchi K.

Development. 2015 Jun 15;142(12):2088-93. doi: 10.1242/dev.114454. Review.

46.

Regulation of vascular endothelial growth factor receptor function in angiogenesis by numb and numb-like.

van Lessen M, Nakayama M, Kato K, Kim JM, Kaibuchi K, Adams RH.

Arterioscler Thromb Vasc Biol. 2015 Aug;35(8):1815-25. doi: 10.1161/ATVBAHA.115.305473. Epub 2015 Jun 11.

PMID:
26069237
47.

IQGAPs as Key Regulators of Actin-cytoskeleton Dynamics.

Watanabe T, Wang S, Kaibuchi K.

Cell Struct Funct. 2015;40(2):69-77. doi: 10.1247/csf.15003. Epub 2015 Jun 6. Review.

48.

Deubiquitinating enzymes regulate Hes1 stability and neuronal differentiation.

Kobayashi T, Iwamoto Y, Takashima K, Isomura A, Kosodo Y, Kawakami K, Nishioka T, Kaibuchi K, Kageyama R.

FEBS J. 2015 Jul;282(13):2411-23. doi: 10.1111/febs.13290. Epub 2015 Apr 23.

49.

Disrupted-in-schizophrenia 1 regulates transport of ITPR1 mRNA for synaptic plasticity.

Tsuboi D, Kuroda K, Tanaka M, Namba T, Iizuka Y, Taya S, Shinoda T, Hikita T, Muraoka S, Iizuka M, Nimura A, Mizoguchi A, Shiina N, Sokabe M, Okano H, Mikoshiba K, Kaibuchi K.

Nat Neurosci. 2015 May;18(5):698-707. doi: 10.1038/nn.3984. Epub 2015 Mar 30.

PMID:
25821909
50.

Developing novel methods to search for substrates of protein kinases such as Rho-kinase.

Nishioka T, Shohag MH, Amano M, Kaibuchi K.

Biochim Biophys Acta. 2015 Oct;1854(10 Pt B):1663-6. doi: 10.1016/j.bbapap.2015.03.001. Epub 2015 Mar 12. Review.

PMID:
25770685

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