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Items: 1 to 50 of 550

1.

Blowhole tangential cecostomy and transanal tube insertion for neonatal cecal perforation in a patient with Hirschsprung's disease in the earlier definitive operation era.

Shirai T, Hirose R, Kai H, Inatomi K, Yanagi Y, Iwanaka T, Iwasaki A.

Surg Case Rep. 2019 Jul 10;5(1):111. doi: 10.1186/s40792-019-0667-9.

PMID:
31292778
2.

Auto-measure emphysematous parameters and pathophysiological gene expression profiles in experimental mouse models of acute and chronic obstructive pulmonary diseases.

Nakashima R, Kamei S, Nohara H, Fujikawa H, Maruta K, Kawakami T, Eto Y, Takahashi N, Suico MA, Takeo T, Nakagata N, Kai H, Shuto T.

J Pharmacol Sci. 2019 Mar 26. pii: S1347-8613(19)30016-7. doi: 10.1016/j.jphs.2019.01.011. [Epub ahead of print]

3.

A cell-based high-throughput screening method to directly examine transthyretin amyloid fibril formation at neutral pH.

Ueda M, Okada M, Mizuguchi M, Kluve-Beckerman B, Kanenawa K, Isoguchi A, Misumi Y, Tasaki M, Ueda A, Kanai A, Sasaki R, Masuda T, Inoue Y, Nomura T, Shinriki S, Shuto T, Kai H, Yamashita T, Matsui H, Benson MD, Ando Y.

J Biol Chem. 2019 Jun 5. pii: jbc.RA119.007851. doi: 10.1074/jbc.RA119.007851. [Epub ahead of print]

4.

Total Syntheses of (+)-Aquatolide and Related Humulanolides.

Takao KI, Kai H, Yamada A, Fukushima Y, Komatsu D, Ogura A, Yoshida K.

Angew Chem Int Ed Engl. 2019 May 22. doi: 10.1002/anie.201904404. [Epub ahead of print]

PMID:
31115973
5.

Japan Aerospace Exploration Agency's public-health monitoring and analysis platform: A satellite-derived environmental information system supporting epidemiological study.

Oyoshi K, Mizukami Y, Kakuda R, Kobayashi Y, Kai H, Tadono T.

Geospat Health. 2019 May 14;14(1). doi: 10.4081/gh.2019.717.

6.

Plasma Exchange Is Highly Effective for Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis Patients With Rapidly Progressive Glomerulonephritis Who Have Advanced to Dialysis Dependence: A Single-Center Case Series.

Nishida R, Kaneko S, Usui J, Kawamura T, Tsunoda R, Tawara T, Fujita A, Nagai K, Kai H, Morito N, Saito C, Yamagata K.

Ther Apher Dial. 2019 Jun;23(3):253-260. doi: 10.1111/1744-9987.12830.

PMID:
31033151
7.

JSH Statement: Asahikawa declaration in promotion of diversity by the Japanese society of hypertension-the JSH Asahikawa declaration.

Nakamura S, Hasebe N, Yatabe M, Kishi T, Ishida M, Ichihara A, Node K, Ishimitsu T, Itoh H, Ito M, Ohishi M, Ohkubo T, Kai H, Kashihara N, Kario K, Saitoh S, Tsuchihashi T, Nishiyama A, Higaki J, Miura K, Rakugi H, Kawano Y, Tamura K, Yatabe T, Ohya Y, Ito S.

Hypertens Res. 2019 Apr 8. doi: 10.1038/s41440-019-0261-3. [Epub ahead of print] No abstract available.

PMID:
30962519
8.

The characterization of AD/PART co-pathology in CJD suggests independent pathogenic mechanisms and no cross-seeding between misfolded Aβ and prion proteins.

Rossi M, Kai H, Baiardi S, Bartoletti-Stella A, Carlà B, Zenesini C, Capellari S, Kitamoto T, Parchi P.

Acta Neuropathol Commun. 2019 Apr 8;7(1):53. doi: 10.1186/s40478-019-0706-6.

9.

Angiotensin-converting enzyme inhibitors versus angiotensin receptor blockers in hypertensive patients with myocardial infarction or heart failure: a systematic review and meta-analysis.

Ohtsubo T, Shibata R, Kai H, Okamoto R, Kumagai E, Kawano H, Fujiwara A, Kitazono T, Murohara T, Arima H.

Hypertens Res. 2019 May;42(5):641-649. doi: 10.1038/s41440-018-0167-5. Epub 2019 Apr 5.

PMID:
30948834
10.

Effects of lowering diastolic blood pressure to <80 mmHg on cardiovascular mortality and events in patients with coronary artery disease: a systematic review and meta-analysis.

Okamoto R, Kumagai E, Kai H, Shibata R, Ohtsubo T, Kawano H, Fujiwara A, Ito M, Fukumoto Y, Arima H.

Hypertens Res. 2019 May;42(5):650-659. doi: 10.1038/s41440-018-0189-z. Epub 2019 Apr 5.

PMID:
30948833
11.

Effects of blood pressure lowering in patients with heart failure with preserved ejection fraction: a systematic review and meta-analysis.

Kawano H, Fujiwara A, Kai H, Kumagai E, Okamoto R, Shibata R, Ohtsubo T, Tamura K, Maemura K, Arima H.

Hypertens Res. 2019 Apr;42(4):504-513. doi: 10.1038/s41440-019-0216-8. Epub 2019 Apr 5.

PMID:
30948821
12.

A PCR-lateral flow assay system based on gold magnetic nanoparticles for CYP2C19 genotyping and its clinical applications.

Xuhong Y, Sinong Z, Jianping L, Yu C, Juanli Z, Chao Z, Desheng L, Kai H, Yali C, Wenli H.

Artif Cells Nanomed Biotechnol. 2019 Dec;47(1):636-643. doi: 10.1080/21691401.2019.1575841.

PMID:
30873882
13.

Supporting elder persons in rural Japanese communities through preventive home visits by nursing students: A qualitative descriptive analysis of students' reports.

Iwasaki R, Hirai K, Kageyama T, Satoh T, Fukuda H, Kai H, Makino K, Magilvy K, Murashima S.

Public Health Nurs. 2019 Jul;36(4):557-563. doi: 10.1111/phn.12596. Epub 2019 Mar 7.

PMID:
30847988
14.

Skeletal Rearrangement of Twisted Thia-Norhexaphyrin: Multiply Annulated Polypyrrolic Aromatic Macrocycles.

Li Q, Ishida M, Kai H, Gu T, Li C, Li X, Baryshnikov G, Liang X, Zhu W, Ågren H, Furuta H, Xie Y.

Angew Chem Int Ed Engl. 2019 Apr 23;58(18):5925-5929. doi: 10.1002/anie.201900010. Epub 2019 Mar 28.

PMID:
30843636
15.

Discovery of NR2B-selective antagonists via scaffold hopping and pharmacokinetic profile optimization.

Anan K, Masui M, Tazawa A, Tomida M, Haga Y, Kume M, Yamamoto S, Shinohara S, Tsuji H, Shimada S, Yagi S, Hasebe N, Kai H.

Bioorg Med Chem Lett. 2019 May 1;29(9):1143-1147. doi: 10.1016/j.bmcl.2019.02.017. Epub 2019 Feb 15.

PMID:
30833109
16.

Pyrrolinone derivatives as a new class of P2X3 receptor antagonists Part 2: Discovery of orally bioavailable compounds.

Tobinaga H, Kameyama T, Asahi K, Horiguchi T, Oohara M, Tada Y, Fuchino K, Jikihara S, Endoh T, Kurihara N, Kanda Y, Ogawa M, Tamura N, Yagi S, Taniguchi E, Takahara Y, Shimada S, Takeyama C, Yamamoto S, Shinohara S, Kai H.

Bioorg Med Chem Lett. 2019 Mar 1;29(5):688-693. doi: 10.1016/j.bmcl.2019.01.039. Epub 2019 Feb 1.

PMID:
30728111
17.

Transthyretin Amyloid Fibril Disrupting Activities of Extracts and Fractions from Juglans mandshurica Maxim. var. cordiformis (Makino) Kitam.

Chaudhary N, Sasaki R, Shuto T, Watanabe M, Kawahara T, Suico MA, Yokoyama T, Mizuguchi M, Kai H, Devkota HP.

Molecules. 2019 Jan 30;24(3). pii: E500. doi: 10.3390/molecules24030500.

18.

Curcumin Down-Regulates Toll-Like Receptor-2 Gene Expression and Function in Human Cystic Fibrosis Bronchial Epithelial Cells.

Chaudhary N, Ueno-Shuto K, Ono T, Ohira Y, Watanabe K, Nasu A, Fujikawa H, Nakashima R, Takahashi N, Suico MA, Kai H, Shuto T.

Biol Pharm Bull. 2019 Mar 1;42(3):489-495. doi: 10.1248/bpb.b18-00928. Epub 2019 Jan 10.

19.

JSH Statement: Kyoto declaration on hypertension research in Asia.

Ito M, Ishimitsu T, Ichihara A, Itoh H, Ohishi M, Ohkubo T, Kai H, Kashihara N, Kario K, Saitoh S, Tsuchihashi T, Nakamura S, Nishiyama A, Node K, Hasebe N, Higaki J, Miura K, Rakugi H, Tamura K, Kawano Y, Yatabe T, Ohya Y, Ito S.

Hypertens Res. 2019 Jun;42(6):759-760. doi: 10.1038/s41440-018-0172-8. Epub 2019 Jan 7. No abstract available.

PMID:
30617311
20.

Integrative expression analysis identifies a novel interplay between CFTR and linc-SUMF1-2 that involves CF-associated gene dysregulation.

Kamei S, Maruta K, Fujikawa H, Nohara H, Ueno-Shuto K, Tasaki Y, Nakashima R, Kawakami T, Eto Y, Suico MA, Suzuki S, Gruenert DC, Li JD, Kai H, Shuto T.

Biochem Biophys Res Commun. 2019 Feb 5;509(2):521-528. doi: 10.1016/j.bbrc.2018.12.152. Epub 2018 Dec 28.

21.

Impact of hepatic HSP72 on insulin signaling.

Kitano S, Kondo T, Matsuyama R, Ono K, Goto R, Takaki Y, Hanatani S, Sakaguchi M, Igata M, Kawashima J, Motoshima H, Matsumura T, Kai H, Araki E.

Am J Physiol Endocrinol Metab. 2019 Feb 1;316(2):E305-E318. doi: 10.1152/ajpendo.00215.2018. Epub 2018 Dec 11.

PMID:
30532989
22.

Quantification of three triterpenic acids in dried rosemary using HPLC-fluorescence detection and 4-(4,5-diphenyl-1H-imidazole-2-yl)benzoyl chloride derivatization.

Wada M, Tojoh Y, Nakamura S, Mutoh J, Kai H, Matsuno K, Nakashima K.

Luminescence. 2019 Feb;34(1):130-132. doi: 10.1002/bio.3581. Epub 2018 Dec 5.

PMID:
30520219
23.

Discovery of naldemedine: A potent and orally available opioid receptor antagonist for treatment of opioid-induced adverse effects.

Inagaki M, Kume M, Tamura Y, Hara S, Goto Y, Haga N, Hasegawa T, Nakamura T, Koike K, Oonishi S, Kanemasa T, Kai H.

Bioorg Med Chem Lett. 2019 Jan 1;29(1):73-77. doi: 10.1016/j.bmcl.2018.11.007. Epub 2018 Nov 7.

PMID:
30446313
24.

Taurine Inhibits TRPV-Dependent Activity to Overcome Oxidative Stress in Caenorhabditis elegans.

Moriuchi M, Nakano Y, Tsurekawa Y, Piruzyan M, Matsuyama S, Nohara H, Suico MA, Shuto T, Kai H.

Biol Pharm Bull. 2018;41(11):1672-1677. doi: 10.1248/bpb.b18-00370.

25.

Free radical scavenging, α-glucosidase inhibitory and lipase inhibitory activities of eighteen Sudanese medicinal plants.

Elbashir SMI, Devkota HP, Wada M, Kishimoto N, Moriuchi M, Shuto T, Misumi S, Kai H, Watanabe T.

BMC Complement Altern Med. 2018 Oct 19;18(1):282. doi: 10.1186/s12906-018-2346-y.

26.

The Japanese Society of Hypertension-Digest of plan for the future.

Node K, Kishi T, Tanaka A, Itoh H, Rakugi H, Ohya Y, Miura K, Okamura T, Ishimitsu T, Ichihara A, Ito M, Ohishi M, Ohkubo T, Kai H, Kashihara N, Kario K, Saitoh S, Tsuchihashi T, Nakamura S, Nishiyama A, Hasebe N, Higaki J, Tamura K, Kawano Y, Yatabe T, Ito S; JSH Future Plan Working Group and Executive Board Members.

Hypertens Res. 2018 Dec;41(12):989-990. doi: 10.1038/s41440-018-0111-8. Epub 2018 Oct 11. No abstract available.

PMID:
30310169
27.

Fluid-permeable enzymatic lactate sensors for micro-volume specimen.

Kai H, Kato Y, Toyosato R, Nishizawa M.

Analyst. 2018 Nov 5;143(22):5545-5551. doi: 10.1039/c8an00979a.

PMID:
30302486
28.

Direct-Injection Electron Ionization-Mass Spectrometry Metabolomics Method for Analyzing Blueberry Leaf Metabolites That Inhibit Adult T-cell Leukemia Proliferation.

Kai H, Uesawa Y, Kunitake H, Morishita K, Okada Y, Matsuno K.

Planta Med. 2019 Jan;85(1):81-87. doi: 10.1055/a-0725-8295. Epub 2018 Sep 13.

PMID:
30212923
29.

Organic electrochromic timer for enzymatic skin patches.

Kai H, Suda W, Yoshida S, Nishizawa M.

Biosens Bioelectron. 2019 Jan 1;123:108-113. doi: 10.1016/j.bios.2018.07.013. Epub 2018 Jul 10.

PMID:
30029842
30.

Neuroimaging-pathological correlations of [18F]THK5351 PET in progressive supranuclear palsy.

Ishiki A, Harada R, Kai H, Sato N, Totsune T, Tomita N, Watanuki S, Hiraoka K, Ishikawa Y, Funaki Y, Iwata R, Furumoto S, Tashiro M, Sasano H, Kitamoto T, Kudo Y, Yanai K, Furukawa K, Okamura N, Arai H.

Acta Neuropathol Commun. 2018 Jun 29;6(1):53. doi: 10.1186/s40478-018-0556-7.

31.

Mild electrical stimulation with heat shock reduces inflammatory symptoms in the imiquimod-induced psoriasis mouse model.

Tsurekawa Y, Morita M, Suico MA, Moriuchi M, Nakano Y, Piruzyan M, Takada M, Fukami S, Shuto T, Kai H.

Exp Dermatol. 2018 Oct;27(10):1092-1097. doi: 10.1111/exd.13720. Epub 2018 Jul 30.

PMID:
29928760
32.

Pyrrolinone derivatives as a new class of P2X3 receptor antagonists. Part 1: Initial structure-activity relationship studies of a hit from a high throughput screening.

Tobinaga H, Kameyama T, Oohara M, Kobayashi N, Ohdan M, Ishizuka N, Kume M, Tomari M, Tanaka Y, Takahashi F, Kinoshita H, Shimada S, Shinohara S, Kai H.

Bioorg Med Chem Lett. 2018 Jul 15;28(13):2338-2342. doi: 10.1016/j.bmcl.2017.04.060. Epub 2017 Apr 19.

PMID:
29805055
33.

Characterization of Non-amyloidogenic G101S Transthyretin.

Wakita Y, Sato T, Chosa K, Suico MA, Sasaki R, Kawano S, Hashimoto N, Teranishi Y, Imai Y, Morioka H, Shuto T, Kai H.

Biol Pharm Bull. 2018;41(4):628-636. doi: 10.1248/bpb.b17-01021.

34.

A Split-Luciferase-Based Trimer Formation Assay as a High-throughput Screening Platform for Therapeutics in Alport Syndrome.

Omachi K, Kamura M, Teramoto K, Kojima H, Yokota T, Kaseda S, Kuwazuru J, Fukuda R, Koyama K, Matsuyama S, Motomura K, Shuto T, Suico MA, Kai H.

Cell Chem Biol. 2018 May 17;25(5):634-643.e4. doi: 10.1016/j.chembiol.2018.02.003. Epub 2018 Mar 8.

35.

Contractile Skeletal Muscle Cells Cultured with a Conducting Soft Wire for Effective, Selective Stimulation.

Nagamine K, Sato H, Kai H, Kaji H, Kanzaki M, Nishizawa M.

Sci Rep. 2018 Feb 2;8(1):2253. doi: 10.1038/s41598-018-20729-y.

36.

Transcriptional regulation of HIV-1 host factor COMMD1 by the Sp family.

Kudo E, Taura M, Suico MA, Goto H, Kai H, Okada S.

Int J Mol Med. 2018 Apr;41(4):2366-2374. doi: 10.3892/ijmm.2018.3386. Epub 2018 Jan 15.

PMID:
29336469
37.

Design and Experimental Verification of a 0.19 V 53 μW 65 nm CMOS Integrated Supply-Sensing Sensor With a Supply-Insensitive Temperature Sensor and an Inductive-Coupling Transmitter for a Self-Powered Bio-sensing System Using a Biofuel Cell.

Kobayashi A, Ikeda K, Ogawa Y, Kai H, Nishizawa M, Nakazato K, Niitsu K.

IEEE Trans Biomed Circuits Syst. 2017 Dec;11(6):1313-1323. doi: 10.1109/TBCAS.2017.2735447.

PMID:
29293424
38.

Zinc Deficiency via a Splice Switch in Zinc Importer ZIP2/SLC39A2 Causes Cystic Fibrosis-Associated MUC5AC Hypersecretion in Airway Epithelial Cells.

Kamei S, Fujikawa H, Nohara H, Ueno-Shuto K, Maruta K, Nakashima R, Kawakami T, Matsumoto C, Sakaguchi Y, Ono T, Suico MA, Boucher RC, Gruenert DC, Takeo T, Nakagata N, Li JD, Kai H, Shuto T.

EBioMedicine. 2018 Jan;27:304-316. doi: 10.1016/j.ebiom.2017.12.025. Epub 2017 Dec 20.

39.

Anaemia is an essential complication of ANCA-associated renal vasculitis: a single center cohort study.

Kawamura T, Usui J, Kaneko S, Tsunoda R, Imai E, Kai H, Morito N, Saito C, Nagata M, Yamagata K.

BMC Nephrol. 2017 Nov 25;18(1):337. doi: 10.1186/s12882-017-0754-8.

40.

Oral Administration of Glucosamine Improves Vascular Endothelial Function by Modulating Intracellular Redox State.

Katoh A, Kai H, Harada H, Niiyama H, Ikeda H.

Int Heart J. 2017 Dec 12;58(6):926-932. doi: 10.1536/ihj.16-534. Epub 2017 Nov 17.

41.

Losartan/hydrochlorothiazide combination is safe and effective for morning hypertension in Very-Elderly patients.

Uchiwa H, Kai H, Iwamoto Y, Anegawa T, Kajimoto H, Fukuda K, Imaizumi T, Fukumoto Y; MAPPY Study Investigators.

Clin Exp Hypertens. 2018;40(3):267-273. doi: 10.1080/10641963.2017.1368536. Epub 2017 Oct 30.

PMID:
29083936
42.

STAT3 inhibition attenuates the progressive phenotypes of Alport syndrome mouse model.

Yokota T, Omachi K, Suico MA, Kamura M, Kojima H, Fukuda R, Motomura K, Teramoto K, Kaseda S, Kuwazuru J, Takeo T, Nakagata N, Shuto T, Kai H.

Nephrol Dial Transplant. 2018 Feb 1;33(2):214-223. doi: 10.1093/ndt/gfx246.

PMID:
28992339
43.

Accelerated Wound Healing on Skin by Electrical Stimulation with a Bioelectric Plaster.

Kai H, Yamauchi T, Ogawa Y, Tsubota A, Magome T, Miyake T, Yamasaki K, Nishizawa M.

Adv Healthc Mater. 2017 Nov;6(22). doi: 10.1002/adhm.201700465. Epub 2017 Sep 20.

PMID:
28929631
44.

Bromide supplementation exacerbated the renal dysfunction, injury and fibrosis in a mouse model of Alport syndrome.

Yokota T, Omachi K, Suico MA, Kojima H, Kamura M, Teramoto K, Kaseda S, Kuwazuru J, Shuto T, Kai H.

PLoS One. 2017 Sep 5;12(9):e0183959. doi: 10.1371/journal.pone.0183959. eCollection 2017.

45.

Correlations of 18F-THK5351 PET with Postmortem Burden of Tau and Astrogliosis in Alzheimer Disease.

Harada R, Ishiki A, Kai H, Sato N, Furukawa K, Furumoto S, Tago T, Tomita N, Watanuki S, Hiraoka K, Ishikawa Y, Funaki Y, Nakamura T, Yoshikawa T, Iwata R, Tashiro M, Sasano H, Kitamoto T, Yanai K, Arai H, Kudo Y, Okamura N.

J Nucl Med. 2018 Apr;59(4):671-674. doi: 10.2967/jnumed.117.197426. Epub 2017 Sep 1.

46.

Effectiveness of Plasmapheresis in a Patient with Anti-glomerular Basement Membrane Antibody Glomerulonephritis with Advanced Kidney Dysfunction.

Usui T, Kai H, Noguchi K, Morito N, Usui J, Saito C, Uesugi N, Nagata M, Yamagata K.

Intern Med. 2017 Sep 15;56(18):2475-2479. doi: 10.2169/internalmedicine.8571-16. Epub 2017 Aug 21.

47.

An array of porous microneedles for transdermal monitoring of intercellular swelling.

Nagamine K, Kubota J, Kai H, Ono Y, Nishizawa M.

Biomed Microdevices. 2017 Sep;19(3):68. doi: 10.1007/s10544-017-0207-y.

PMID:
28776235
48.

Discovery of orally bioavailable cyclohexanol-based NR2B-selective NMDA receptor antagonists with analgesic activity utilizing a scaffold hopping approach.

Anan K, Masui M, Hara S, Ohara M, Kume M, Yamamoto S, Shinohara S, Tsuji H, Shimada S, Yagi S, Hasebe N, Kai H.

Bioorg Med Chem Lett. 2017 Sep 1;27(17):4194-4198. doi: 10.1016/j.bmcl.2017.06.076. Epub 2017 Jul 5.

PMID:
28754363
49.

Intraoperative nerve monitoring reduces recurrent laryngeal nerve injury in geriatric patients undergoing thyroid surgery.

Kai H, Xixia L, Miaoyun L, Qinchang C, Xinzhi P, Dingyuan L, Honghao L.

Acta Otolaryngol. 2017 Dec;137(12):1275-1280. doi: 10.1080/00016489.2017.1354397. Epub 2017 Jul 25.

PMID:
28741396
50.

A nationwide prospective cohort study of patients with advanced chronic kidney disease in Japan: The Reach-J CKD cohort study.

Hoshino J, Nagai K, Kai H, Saito C, Ito Y, Asahi K, Kondo M, Iseki K, Iseki C, Okada H, Kashihara N, Narita I, Wada T, Combe C, Pisoni RL, Robinson BM, Yamagata K.

Clin Exp Nephrol. 2018 Apr;22(2):309-317. doi: 10.1007/s10157-017-1453-2. Epub 2017 Jul 24.

PMID:
28741051

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