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Items: 19

1.

Tetrasubstituted pyridines as potent and selective AKT inhibitors: Reduced CYP450 and hERG inhibition of aminopyridines.

Lin H, Yamashita DS, Xie R, Zeng J, Wang W, Leber J, Safonov IG, Verma S, Li M, Lafrance L, Venslavsky J, Takata D, Luengo JI, Kahana JA, Zhang S, Robell KA, Levy D, Kumar R, Choudhry AE, Schaber M, Lai Z, Brown BS, Donovan BT, Minthorn EA, Brown KK, Heerding DA.

Bioorg Med Chem Lett. 2010 Jan 15;20(2):684-8. doi: 10.1016/j.bmcl.2009.11.061. Epub 2009 Dec 16.

PMID:
20006500
2.

Mechanism and management of AKT inhibitor-induced hyperglycemia.

Crouthamel MC, Kahana JA, Korenchuk S, Zhang SY, Sundaresan G, Eberwein DJ, Brown KK, Kumar R.

Clin Cancer Res. 2009 Jan 1;15(1):217-25. doi: 10.1158/1078-0432.CCR-08-1253.

3.

AKT inhibitor, GSK690693, induces growth inhibition and apoptosis in acute lymphoblastic leukemia cell lines.

Levy DS, Kahana JA, Kumar R.

Blood. 2009 Feb 19;113(8):1723-9. doi: 10.1182/blood-2008-02-137737. Epub 2008 Dec 8.

PMID:
19064730
4.

Use of the A. victoria green fluorescent protein to study protein dynamics in vivo.

Kahana JA, Silver PA.

Curr Protoc Neurosci. 2001 May;Chapter 5:Unit 5.15. doi: 10.1002/0471142301.ns0515s14.

PMID:
18428498
5.

Characterization of an Akt kinase inhibitor with potent pharmacodynamic and antitumor activity.

Rhodes N, Heerding DA, Duckett DR, Eberwein DJ, Knick VB, Lansing TJ, McConnell RT, Gilmer TM, Zhang SY, Robell K, Kahana JA, Geske RS, Kleymenova EV, Choudhry AE, Lai Z, Leber JD, Minthorn EA, Strum SL, Wood ER, Huang PS, Copeland RA, Kumar R.

Cancer Res. 2008 Apr 1;68(7):2366-74. doi: 10.1158/0008-5472.CAN-07-5783.

6.

Use of the A. victoria green fluorescent protein to study protein dynamics in vivo.

Kahana JA, Silver PA.

Curr Protoc Mol Biol. 2001 May;Chapter 9:Unit9.7C. doi: 10.1002/0471142727.mb0907cs34.

PMID:
18265287
7.

The uses of green fluorescent protein in yeasts.

Hitchcock AL, Kahana JA, Silver PA.

Methods Biochem Anal. 2006;47:179-201. Review. No abstract available.

PMID:
16335714
8.

Identification and characterization of pleckstrin-homology-domain-dependent and isoenzyme-specific Akt inhibitors.

Barnett SF, Defeo-Jones D, Fu S, Hancock PJ, Haskell KM, Jones RE, Kahana JA, Kral AM, Leander K, Lee LL, Malinowski J, McAvoy EM, Nahas DD, Robinson RG, Huber HE.

Biochem J. 2005 Jan 15;385(Pt 2):399-408.

9.

Mps1 is a kinetochore-associated kinase essential for the vertebrate mitotic checkpoint.

Abrieu A, Magnaghi-Jaulin L, Kahana JA, Peter M, Castro A, Vigneron S, Lorca T, Cleveland DW, Labbé JC.

Cell. 2001 Jul 13;106(1):83-93.

10.

Use of the A. victoria green fluorescent protein to study protein dynamics in vivo.

Kahana JA, Silver PA.

Curr Protoc Pharmacol. 2001 May;Chapter 6:Unit 6.6. doi: 10.1002/0471141755.ph0606s05.

PMID:
21965077
11.

Stay tuned for some importin news about spindle assembly.

Marshall WF, Kahana JA.

Trends Cell Biol. 2001 Apr;11(4):148. No abstract available.

PMID:
11306278
12.

Cell cycle. Some importin news about spindle assembly.

Kahana JA, Cleveland DW.

Science. 2001 Mar 2;291(5509):1718-9. No abstract available.

PMID:
11253198
13.

CENP-E as an essential component of the mitotic checkpoint in vitro.

Abrieu A, Kahana JA, Wood KW, Cleveland DW.

Cell. 2000 Sep 15;102(6):817-26.

14.

Mutants affecting the structure of the cortical endoplasmic reticulum in Saccharomyces cerevisiae.

Prinz WA, Grzyb L, Veenhuis M, Kahana JA, Silver PA, Rapoport TA.

J Cell Biol. 2000 Aug 7;150(3):461-74.

15.

Beyond nuclear transport. Ran-GTP as a determinant of spindle assembly.

Kahana JA, Cleveland DW.

J Cell Biol. 1999 Sep 20;146(6):1205-10. Review. No abstract available.

16.

Slk19p is a centromere protein that functions to stabilize mitotic spindles.

Zeng X, Kahana JA, Silver PA, Morphew MK, McIntosh JR, Fitch IT, Carbon J, Saunders WS.

J Cell Biol. 1999 Jul 26;146(2):415-25.

17.
18.

The yeast dynactin complex is involved in partitioning the mitotic spindle between mother and daughter cells during anaphase B.

Kahana JA, Schlenstedt G, Evanchuk DM, Geiser JR, Hoyt MA, Silver PA.

Mol Biol Cell. 1998 Jul;9(7):1741-56.

19.

Kinetics of spindle pole body separation in budding yeast.

Kahana JA, Schnapp BJ, Silver PA.

Proc Natl Acad Sci U S A. 1995 Oct 10;92(21):9707-11.

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