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Items: 1 to 50 of 60

1.

The Macromolecular Machines that Duplicate the Escherichia coli Chromosome as Targets for Drug Discovery.

Kaguni JM.

Antibiotics (Basel). 2018 Mar 14;7(1). pii: E23. doi: 10.3390/antibiotics7010023. Review.

2.

DnaC, the indispensable companion of DnaB helicase, controls the accessibility of DnaB helicase by primase.

Felczak MM, Chodavarapu S, Kaguni JM.

J Biol Chem. 2017 Dec 22;292(51):20871-20882. doi: 10.1074/jbc.M117.807644. Epub 2017 Oct 25.

3.

Dynamic assembly of Hda and the sliding clamp in the regulation of replication licensing.

Kim JS, Nanfara MT, Chodavarapu S, Jin KS, Babu VMP, Ghazy MA, Chung S, Kaguni JM, Sutton MD, Cho Y.

Nucleic Acids Res. 2017 Apr 20;45(7):3888-3905. doi: 10.1093/nar/gkx081.

4.

Replication Initiation in Bacteria.

Chodavarapu S, Kaguni JM.

Enzymes. 2016;39:1-30. doi: 10.1016/bs.enz.2016.03.001. Epub 2016 Apr 20. Review.

5.

Substitutions of Conserved Residues in the C-terminal Region of DnaC Cause Thermolability in Helicase Loading.

Felczak MM, Sage JM, Hupert-Kocurek K, Aykul S, Kaguni JM.

J Biol Chem. 2016 Feb 26;291(9):4803-12. doi: 10.1074/jbc.M115.708586. Epub 2016 Jan 4.

6.

DnaC traps DnaB as an open ring and remodels the domain that binds primase.

Chodavarapu S, Jones AD, Feig M, Kaguni JM.

Nucleic Acids Res. 2016 Jan 8;44(1):210-20. doi: 10.1093/nar/gkv961. Epub 2015 Sep 29.

7.

Mutant DnaAs of Escherichia coli that are refractory to negative control.

Chodavarapu S, Felczak MM, Simmons LA, Murillo A, Kaguni JM.

Nucleic Acids Res. 2013 Dec;41(22):10254-67. doi: 10.1093/nar/gkt774. Epub 2013 Aug 29.

8.

Helicase loading at chromosomal origins of replication.

Bell SP, Kaguni JM.

Cold Spring Harb Perspect Biol. 2013 Jun 1;5(6). pii: a010124. doi: 10.1101/cshperspect.a010124. Review.

9.

The rcbA gene product reduces spontaneous and induced chromosome breaks in Escherichia coli.

Felczak MM, Kaguni JM.

J Bacteriol. 2012 May;194(9):2152-64. doi: 10.1128/JB.06390-11. Epub 2012 Feb 17.

10.

Replication initiation at the Escherichia coli chromosomal origin.

Kaguni JM.

Curr Opin Chem Biol. 2011 Oct;15(5):606-13. doi: 10.1016/j.cbpa.2011.07.016. Epub 2011 Aug 18.

11.

Two forms of ribosomal protein L2 of Escherichia coli that inhibit DnaA in DNA replication.

Chodavarapu S, Felczak MM, Kaguni JM.

Nucleic Acids Res. 2011 May;39(10):4180-91. doi: 10.1093/nar/gkq1203. Epub 2011 Feb 2.

12.

Primase directs the release of DnaC from DnaB.

Makowska-Grzyska M, Kaguni JM.

Mol Cell. 2010 Jan 15;37(1):90-101. doi: 10.1016/j.molcel.2009.12.031.

13.

DnaAcos hyperinitiates by circumventing regulatory pathways that control the frequency of initiation in Escherichia coli.

Felczak MM, Kaguni JM.

Mol Microbiol. 2009 Jun;72(6):1348-63. doi: 10.1111/j.1365-2958.2009.06724.x. Epub 2009 Apr 30.

14.

Escherichia coli Dps interacts with DnaA protein to impede initiation: a model of adaptive mutation.

Chodavarapu S, Gomez R, Vicente M, Kaguni JM.

Mol Microbiol. 2008 Mar;67(6):1331-46. doi: 10.1111/j.1365-2958.2008.06127.x. Epub 2008 Feb 15.

15.

Escherichia coli DnaA interacts with HU in initiation at the E. coli replication origin.

Chodavarapu S, Felczak MM, Yaniv JR, Kaguni JM.

Mol Microbiol. 2008 Feb;67(4):781-92. doi: 10.1111/j.1365-2958.2007.06094.x. Epub 2007 Dec 19.

16.

Genetic method to analyze essential genes of Escherichia coli.

Hupert-Kocurek K, Sage JM, Makowska-Grzyska M, Kaguni JM.

Appl Environ Microbiol. 2007 Nov;73(21):7075-82. Epub 2007 Sep 14.

17.

DnaA: controlling the initiation of bacterial DNA replication and more.

Kaguni JM.

Annu Rev Microbiol. 2006;60:351-75. Review.

PMID:
16753031
18.

Escherichia coli DnaA protein: specific biochemical defects of mutant DnaAs reduce initiation frequency to suppress a temperature-sensitive dnaX mutation.

Walker JR, Severson KA, Hermandson MJ, Blinkova A, Carr KM, Kaguni JM.

Biochimie. 2006 Jan;88(1):1-10. Epub 2005 Sep 21.

PMID:
16225979
19.

An essential tryptophan of Escherichia coli DnaA protein functions in oligomerization at the E. coli replication origin.

Felczak MM, Simmons LA, Kaguni JM.

J Biol Chem. 2005 Jul 1;280(26):24627-33. Epub 2005 May 5.

20.
21.

Hyperinitiation of DNA replication in Escherichia coli leads to replication fork collapse and inviability.

Simmons LA, Breier AM, Cozzarelli NR, Kaguni JM.

Mol Microbiol. 2004 Jan;51(2):349-58.

24.

Escherichia coli DnaA protein loads a single DnaB helicase at a DnaA box hairpin.

Carr KM, Kaguni JM.

J Biol Chem. 2002 Oct 18;277(42):39815-22. Epub 2002 Aug 2.

25.

Stoichiometry of DnaA and DnaB protein in initiation at the Escherichia coli chromosomal origin.

Carr KM, Kaguni JM.

J Biol Chem. 2001 Nov 30;276(48):44919-25. Epub 2001 Sep 10.

26.

Essential amino acids of Escherichia coli DnaC protein in an N-terminal domain interact with DnaB helicase.

Ludlam AV, McNatt MW, Carr KM, Kaguni JM.

J Biol Chem. 2001 Jul 20;276(29):27345-53. Epub 2001 May 1.

27.

Escherichia coli DnaA protein. The N-terminal domain and loading of DnaB helicase at the E. coli chromosomal origin.

Sutton MD, Carr KM, Vicente M, Kaguni JM.

J Biol Chem. 1998 Dec 18;273(51):34255-62.

28.
29.

Role of adenine nucleotides, molecular chaperones and chaperonins in stabilization of DnaA initiator protein of Escherichia coli.

Banecki B, Kaguni JM, Marszalek J.

Biochim Biophys Acta. 1998 Oct 23;1442(1):39-48.

PMID:
9767098
30.

The Escherichia coli dnaA gene: four functional domains.

Sutton MD, Kaguni JM.

J Mol Biol. 1997 Dec 12;274(4):546-61.

PMID:
9417934
31.

Novel alleles of the Escherichia coli dnaA gene.

Sutton MD, Kaguni JM.

J Mol Biol. 1997 Sep 5;271(5):693-703. Erratum in: J Mol Biol 1998 Feb 27;276(3):683-5.

PMID:
9299320
32.
33.

Escherichia coli DnaA protein: the replication initiator.

Kaguni JM.

Mol Cells. 1997 Apr 30;7(2):145-57. Review. No abstract available.

34.

Domains of DnaA protein involved in interaction with DnaB protein, and in unwinding the Escherichia coli chromosomal origin.

Marszalek J, Zhang W, Hupp TR, Margulies C, Carr KM, Cherry S, Kaguni JM.

J Biol Chem. 1996 Aug 2;271(31):18535-42.

35.
37.
38.
39.

Synthesis of DnaK protein during the division cycle of Escherichia coli.

Hupp TR, Keasling JD, Cooper S, Kaguni JM.

Res Microbiol. 1994 Feb;145(2):99-109.

PMID:
8090998
40.

Open-complex formation by the host initiator, DnaA, at the origin of P1 plasmid replication.

Mukhopadhyay G, Carr KM, Kaguni JM, Chattoraj DK.

EMBO J. 1993 Dec;12(12):4547-54.

42.
43.
44.

Defective replication activity of a dominant-lethal dnaB gene product from Escherichia coli.

Marszalek J, Kaguni JM.

J Biol Chem. 1992 Sep 25;267(27):19334-40.

45.

Enzyme-labeled probes for nucleic acid hybridization.

Kaguni JM, Kaguni LS.

Methods Biochem Anal. 1992;36:115-27. Review. No abstract available.

PMID:
1552865
46.
47.
48.

dnaA protein regulates transcriptions of the rpoH gene of Escherichia coli.

Wang QP, Kaguni JM.

J Biol Chem. 1989 May 5;264(13):7338-44.

49.
50.

Purification and characterization of the dnaA46 gene product.

Hwang DS, Kaguni JM.

J Biol Chem. 1988 Aug 5;263(22):10625-32.

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