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Items: 1 to 50 of 564

1.

Cardiolipin-dependent mitophagy guides outcome after traumatic brain injury.

Chao H, Lin C, Zuo Q, Liu Y, Xiao M, Xu X, Li Z, Bao Z, Chen H, You Y, Kochanek PM, Yin H, Liu N, Kagan VE, Bayır H, Ji J.

J Neurosci. 2019 Jan 9. pii: 3415-17. doi: 10.1523/JNEUROSCI.3415-17.2018. [Epub ahead of print]

PMID:
30626699
2.

Mitochondria modulate programmed neuritic retraction.

Baranov SV, Baranova OV, Yablonska S, Suofu Y, Vazquez AL, Kozai TDY, Cui XT, Ferrando LM, Larkin TM, Tyurina YY, Kagan VE, Carlisle DL, Kristal BS, Friedlander RM.

Proc Natl Acad Sci U S A. 2019 Jan 8;116(2):650-659. doi: 10.1073/pnas.1811021116. Epub 2018 Dec 24.

PMID:
30584104
3.

Ferroptosis Contributes to Neuronal Death and Functional Outcome After Traumatic Brain Injury.

Kenny EM, Fidan E, Yang Q, Anthonymuthu TS, New LA, Meyer EA, Wang H, Kochanek PM, Dixon CE, Kagan VE, Bayır H.

Crit Care Med. 2018 Dec 6. doi: 10.1097/CCM.0000000000003555. [Epub ahead of print]

PMID:
30531185
4.

Empowerment of 15-lipoxygenase catalytic competence in selective oxidation of membrane ETE-PE to ferroptotic death signals, HpETE-PE.

Anthonymuthu TS, Kenny EM, Shrivastava IH, Tyurina YY, Hier ZE, Ting HC, Dar H, Tyurin VA, Nesterova A, Amoscato AA, Mikulska-Ruminska K, Rosenbaum JC, Mao G, Jinming Z, Conrad M, Kellum JA, Wenzel SE, VanDemark AP, Bahar I, Kagan VE, Bayir H.

J Am Chem Soc. 2018 Dec 7. doi: 10.1021/jacs.8b09913. [Epub ahead of print]

PMID:
30525572
5.

Paths to successful translation of new therapies for severe TBI in the golden age of traumatic brain injury research: A Pittsburgh vision.

Kochanek PM, Jackson TC, Jha R, Clark RSB, Okonkwo DO, Bayir H, Poloyac SM, Wagner AK M.D, Empey PE, Conley YP, Bell MJ, Kline AE, Bondi CO, Simon DW, Carlson SW, Puccio AM, Horvat CM, Au A, Elmer J, Treble-Barna A, Ikonomovic M, Shutter L, Taylor DL, Stern AM, Graham SH, Kagan VE, Jackson EK, Wisniewski SR, Dixon CE.

J Neurotrauma. 2018 Dec 6. doi: 10.1089/neu.2018.6203. [Epub ahead of print]

PMID:
30520681
6.

Disentangling oxidation/hydrolysis reactions of brain mitochondrial cardiolipins in pathogenesis of traumatic injury.

Chao H, Anthonymuthu TS, Kenny EM, Amoscato AA, Cole LK, Hatch GM, Ji J, Kagan VE, Bayır H.

JCI Insight. 2018 Nov 2;3(21). pii: 97677. doi: 10.1172/jci.insight.97677. [Epub ahead of print]

7.

Targeting myeloid regulators by paclitaxel-loaded enzymatically degradable nanocups.

Burkert SC, Shurin GV, White DL, He X, Kapralov AA, Kagan VE, Shurin MR, Star A.

Nanoscale. 2018 Sep 27;10(37):17990-18000. doi: 10.1039/c8nr04437f.

PMID:
30226240
8.

Iron catalysis of lipid peroxidation in ferroptosis: Regulated enzymatic or random free radical reaction?

Stoyanovsky DA, Tyurina YY, Shrivastava I, Bahar I, Tyurin VA, Protchenko O, Jadhav S, Bolevich SB, Kozlov AV, Vladimirov YA, Shvedova AA, Philpott CC, Bayir H, Kagan VE.

Free Radic Biol Med. 2018 Sep 12. pii: S0891-5849(18)31563-6. doi: 10.1016/j.freeradbiomed.2018.09.008. [Epub ahead of print]

PMID:
30217775
9.

Pseudomonas aeruginosa utilizes host polyunsaturated phosphatidylethanolamines to trigger theft-ferroptosis in bronchial epithelium.

Dar HH, Tyurina YY, Mikulska-Ruminska K, Shrivastava I, Ting HC, Tyurin VA, Krieger J, St Croix CM, Watkins S, Bayir E, Mao G, Armbruster CR, Kapralov A, Wang H, Parsek MR, Anthonymuthu TS, Ogunsola AF, Flitter BA, Freedman CJ, Gaston JR, Holman TR, Pilewski JM, Greenberger JS, Mallampalli RK, Doi Y, Lee JS, Bahar I, Bomberger JM, Bayır H, Kagan VE.

J Clin Invest. 2018 Oct 1;128(10):4639-4653. doi: 10.1172/JCI99490. Epub 2018 Sep 10.

10.

Aberrant cardiolipin metabolism is associated with cognitive deficiency and hippocampal alteration in tafazzin knockdown mice.

Cole LK, Kim JH, Amoscato AA, Tyurina YY, Bay R H, Karimi B, Siddiqui TJ, Kagan VE, Hatch GM, Kauppinen TM.

Biochim Biophys Acta Mol Basis Dis. 2018 Oct;1864(10):3353-3367. doi: 10.1016/j.bbadis.2018.07.022. Epub 2018 Jul 25.

PMID:
30055293
11.

Aiming for the target: Mitochondrial drug delivery in traumatic brain injury.

Lamade AM, Kenny EM, Anthonymuthu TS, Soysal E, Clark RSB, Kagan VE, Bayır H.

Neuropharmacology. 2019 Feb;145(Pt B):209-219. doi: 10.1016/j.neuropharm.2018.07.014. Epub 2018 Jul 30. Review.

PMID:
30009835
12.

Oxidized phospholipid signaling in traumatic brain injury.

Anthonymuthu TS, Kenny EM, Lamade AM, Kagan VE, Bayır H.

Free Radic Biol Med. 2018 Aug 20;124:493-503. doi: 10.1016/j.freeradbiomed.2018.06.031. Epub 2018 Jun 30. Review.

PMID:
29964171
13.

Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma.

Hassannia B, Wiernicki B, Ingold I, Qu F, Van Herck S, Tyurina YY, Bayır H, Abhari BA, Angeli JPF, Choi SM, Meul E, Heyninck K, Declerck K, Chirumamilla CS, Lahtela-Kakkonen M, Van Camp G, Krysko DV, Ekert PG, Fulda S, De Geest BG, Conrad M, Kagan VE, Vanden Berghe W, Vandenabeele P, Vanden Berghe T.

J Clin Invest. 2018 Aug 1;128(8):3341-3355. doi: 10.1172/JCI99032. Epub 2018 Jun 25.

14.

Genetic re-engineering of polyunsaturated phospholipid profile of Saccharomyces cerevisiae identifies a novel role for Cld1 in mitigating the effects of cardiolipin peroxidation.

Lou W, Ting HC, Reynolds CA, Tyurina YY, Tyurin VA, Li Y, Ji J, Yu W, Liang Z, Stoyanovsky DA, Anthonymuthu TS, Frasso MA, Wipf P, Greenberger JS, Bayır H, Kagan VE, Greenberg ML.

Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Oct;1863(10):1354-1368. doi: 10.1016/j.bbalip.2018.06.016. Epub 2018 Jun 20.

PMID:
29935382
15.

Regulation of lipid peroxidation and ferroptosis in diverse species.

Conrad M, Kagan VE, Bayir H, Pagnussat GC, Head B, Traber MG, Stockwell BR.

Genes Dev. 2018 May 1;32(9-10):602-619. doi: 10.1101/gad.314674.118. Review.

16.

FINO2 initiates ferroptosis through GPX4 inactivation and iron oxidation.

Gaschler MM, Andia AA, Liu H, Csuka JM, Hurlocker B, Vaiana CA, Heindel DW, Zuckerman DS, Bos PH, Reznik E, Ye LF, Tyurina YY, Lin AJ, Shchepinov MS, Chan AY, Peguero-Pereira E, Fomich MA, Daniels JD, Bekish AV, Shmanai VV, Kagan VE, Mahal LK, Woerpel KA, Stockwell BR.

Nat Chem Biol. 2018 May;14(5):507-515. doi: 10.1038/s41589-018-0031-6. Epub 2018 Apr 2.

17.

Structural characterization of cardiolipin-driven activation of cytochrome c into a peroxidase and membrane perturbation.

Mohammadyani D, Yanamala N, Samhan-Arias AK, Kapralov AA, Stepanov G, Nuar N, Planas-Iglesias J, Sanghera N, Kagan VE, Klein-Seetharaman J.

Biochim Biophys Acta Biomembr. 2018 May;1860(5):1057-1068. doi: 10.1016/j.bbamem.2018.01.009. Epub 2018 Jan 6.

PMID:
29317202
18.

Lipid bodies containing oxidatively truncated lipids block antigen cross-presentation by dendritic cells in cancer.

Veglia F, Tyurin VA, Mohammadyani D, Blasi M, Duperret EK, Donthireddy L, Hashimoto A, Kapralov A, Amoscato A, Angelini R, Patel S, Alicea-Torres K, Weiner D, Murphy ME, Klein-Seetharaman J, Celis E, Kagan VE, Gabrilovich DI.

Nat Commun. 2017 Dec 14;8(1):2122. doi: 10.1038/s41467-017-02186-9.

19.

Mediation of the single-walled carbon nanotubes induced pulmonary fibrogenic response by osteopontin and TGF-β1.

Khaliullin TO, Kisin ER, Murray AR, Yanamala N, Shurin MR, Gutkin DW, Fatkhutdinova LM, Kagan VE, Shvedova AA.

Exp Lung Res. 2017 Oct;43(8):311-326. doi: 10.1080/01902148.2017.1377783.

PMID:
29140132
20.

PEBP1 Wardens Ferroptosis by Enabling Lipoxygenase Generation of Lipid Death Signals.

Wenzel SE, Tyurina YY, Zhao J, St Croix CM, Dar HH, Mao G, Tyurin VA, Anthonymuthu TS, Kapralov AA, Amoscato AA, Mikulska-Ruminska K, Shrivastava IH, Kenny EM, Yang Q, Rosenbaum JC, Sparvero LJ, Emlet DR, Wen X, Minami Y, Qu F, Watkins SC, Holman TR, VanDemark AP, Kellum JA, Bahar I, Bayır H, Kagan VE.

Cell. 2017 Oct 19;171(3):628-641.e26. doi: 10.1016/j.cell.2017.09.044.

21.

NME4/nucleoside diphosphate kinase D in cardiolipin signaling and mitophagy.

Schlattner U, Tokarska-Schlattner M, Epand RM, Boissan M, Lacombe ML, Kagan VE.

Lab Invest. 2018 Feb;98(2):228-232. doi: 10.1038/labinvest.2017.113. Epub 2017 Oct 16. Review.

PMID:
29035377
22.

Necroptotic cell death in anti-cancer therapy.

Krysko O, Aaes TL, Kagan VE, D'Herde K, Bachert C, Leybaert L, Vandenabeele P, Krysko DV.

Immunol Rev. 2017 Nov;280(1):207-219. doi: 10.1111/imr.12583. Review.

PMID:
29027225
23.

Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease.

Stockwell BR, Friedmann Angeli JP, Bayir H, Bush AI, Conrad M, Dixon SJ, Fulda S, Gascón S, Hatzios SK, Kagan VE, Noel K, Jiang X, Linkermann A, Murphy ME, Overholtzer M, Oyagi A, Pagnussat GC, Park J, Ran Q, Rosenfeld CS, Salnikow K, Tang D, Torti FM, Torti SV, Toyokuni S, Woerpel KA, Zhang DD.

Cell. 2017 Oct 5;171(2):273-285. doi: 10.1016/j.cell.2017.09.021. Review.

24.

Lipid homeostasis and inflammatory activation are disturbed in classically activated macrophages with peroxisomal β-oxidation deficiency.

Geric I, Tyurina YY, Krysko O, Krysko DV, De Schryver E, Kagan VE, Van Veldhoven PP, Baes M, Verheijden S.

Immunology. 2018 Mar;153(3):342-356. doi: 10.1111/imm.12844. Epub 2017 Oct 26.

PMID:
28940384
25.

"Only a Life Lived for Others Is Worth Living": Redox Signaling by Oxygenated Phospholipids in Cell Fate Decisions.

Tyurina YY, Shrivastava I, Tyurin VA, Mao G, Dar HH, Watkins S, Epperly M, Bahar I, Shvedova AA, Pitt B, Wenzel SE, Mallampalli RK, Sadovsky Y, Gabrilovich D, Greenberger JS, Bayır H, Kagan VE.

Antioxid Redox Signal. 2018 Nov 1;29(13):1333-1358. doi: 10.1089/ars.2017.7124. Epub 2017 Oct 16.

PMID:
28835115
26.

Ins and Outs in Environmental and Occupational Safety Studies of Asthma and Engineered Nanomaterials.

Dobrovolskaia MA, Shurin MR, Kagan VE, Shvedova AA.

ACS Nano. 2017 Aug 22;11(8):7565-7571. doi: 10.1021/acsnano.7b04916. Epub 2017 Jul 24.

PMID:
28737932
27.

Nanoemitters and innate immunity: the role of surfactants and bio-coronas in myeloperoxidase-catalyzed oxidation of pristine single-walled carbon nanotubes.

Chiu CF, Dar HH, Kapralov AA, Robinson RAS, Kagan VE, Star A.

Nanoscale. 2017 May 11;9(18):5948-5956. doi: 10.1039/c6nr07706d.

PMID:
28440832
28.

Global assessment of oxidized free fatty acids in brain reveals an enzymatic predominance to oxidative signaling after trauma.

Anthonymuthu TS, Kenny EM, Amoscato AA, Lewis J, Kochanek PM, Kagan VE, Bayır H.

Biochim Biophys Acta Mol Basis Dis. 2017 Oct;1863(10 Pt B):2601-2613. doi: 10.1016/j.bbadis.2017.03.015. Epub 2017 Mar 25.

29.

Gas Cluster Ion Beam Time-of-Flight Secondary Ion Mass Spectrometry High-Resolution Imaging of Cardiolipin Speciation in the Brain: Identification of Molecular Losses after Traumatic Injury.

Tian H, Sparvero LJ, Amoscato AA, Bloom A, Bayır H, Kagan VE, Winograd N.

Anal Chem. 2017 Apr 18;89(8):4611-4619. doi: 10.1021/acs.analchem.7b00164. Epub 2017 Mar 29.

30.

Defect-Induced Near-Infrared Photoluminescence of Single-Walled Carbon Nanotubes Treated with Polyunsaturated Fatty Acids.

Chiu CF, Saidi WA, Kagan VE, Star A.

J Am Chem Soc. 2017 Apr 5;139(13):4859-4865. doi: 10.1021/jacs.7b00390. Epub 2017 Mar 22.

PMID:
28288512
31.

Elimination of the unnecessary: Intra- and extracellular signaling by anionic phospholipids.

Kagan VE, Bayır H, Tyurina YY, Bolevich SB, Maguire JJ, Fadeel B, Balasubramanian K.

Biochem Biophys Res Commun. 2017 Jan 15;482(3):482-490. doi: 10.1016/j.bbrc.2016.11.005. Epub 2017 Feb 3. Review.

32.

The mito-DAMP cardiolipin blocks IL-10 production causing persistent inflammation during bacterial pneumonia.

Chakraborty K, Raundhal M, Chen BB, Morse C, Tyurina YY, Khare A, Oriss TB, Huff R, Lee JS, St Croix CM, Watkins S, Mallampalli RK, Kagan VE, Ray A, Ray P.

Nat Commun. 2017 Jan 11;8:13944. doi: 10.1038/ncomms13944.

33.

Magic angle spinning 31P NMR spectroscopy reveals two essentially identical ionization states for the cardiolipin phosphates in phospholipid liposomes.

Kooijman EE, Swim LA, Graber ZT, Tyurina YY, Bayır H, Kagan VE.

Biochim Biophys Acta Biomembr. 2017 Jan;1859(1):61-68. doi: 10.1016/j.bbamem.2016.10.013. Epub 2016 Oct 27.

34.

Lipidomics Characterization of Biosynthetic and Remodeling Pathways of Cardiolipins in Genetically and Nutritionally Manipulated Yeast Cells.

Tyurina YY, Lou W, Qu F, Tyurin VA, Mohammadyani D, Liu J, Hüttemann M, Frasso MA, Wipf P, Bayir H, Greenberg ML, Kagan VE.

ACS Chem Biol. 2017 Jan 20;12(1):265-281. doi: 10.1021/acschembio.6b00995. Epub 2016 Dec 16.

35.

ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition.

Doll S, Proneth B, Tyurina YY, Panzilius E, Kobayashi S, Ingold I, Irmler M, Beckers J, Aichler M, Walch A, Prokisch H, Trümbach D, Mao G, Qu F, Bayir H, Füllekrug J, Scheel CH, Wurst W, Schick JA, Kagan VE, Angeli JP, Conrad M.

Nat Chem Biol. 2017 Jan;13(1):91-98. doi: 10.1038/nchembio.2239. Epub 2016 Nov 14.

36.

Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis.

Kagan VE, Mao G, Qu F, Angeli JP, Doll S, Croix CS, Dar HH, Liu B, Tyurin VA, Ritov VB, Kapralov AA, Amoscato AA, Jiang J, Anthonymuthu T, Mohammadyani D, Yang Q, Proneth B, Klein-Seetharaman J, Watkins S, Bahar I, Greenberger J, Mallampalli RK, Stockwell BR, Tyurina YY, Conrad M, Bayır H.

Nat Chem Biol. 2017 Jan;13(1):81-90. doi: 10.1038/nchembio.2238. Epub 2016 Nov 14.

37.

A Topical Mitochondria-Targeted Redox-Cycling Nitroxide Mitigates Oxidative Stress-Induced Skin Damage.

Brand RM, Epperly MW, Stottlemyer JM, Skoda EM, Gao X, Li S, Huq S, Wipf P, Kagan VE, Greenberger JS, Falo LD Jr.

J Invest Dermatol. 2017 Mar;137(3):576-586. doi: 10.1016/j.jid.2016.09.033. Epub 2016 Oct 26.

38.

Isolation of human trophoblastic extracellular vesicles and characterization of their cargo and antiviral activity.

Ouyang Y, Bayer A, Chu T, Tyurin VA, Kagan VE, Morelli AE, Coyne CB, Sadovsky Y.

Placenta. 2016 Nov;47:86-95. doi: 10.1016/j.placenta.2016.09.008. Epub 2016 Sep 14.

39.

Phosphorylation of Cytochrome c Threonine 28 Regulates Electron Transport Chain Activity in Kidney: IMPLICATIONS FOR AMP KINASE.

Mahapatra G, Varughese A, Ji Q, Lee I, Liu J, Vaishnav A, Sinkler C, Kapralov AA, Moraes CT, Sanderson TH, Stemmler TL, Grossman LI, Kagan VE, Brunzelle JS, Salomon AR, Edwards BF, Hüttemann M.

J Biol Chem. 2017 Jan 6;292(1):64-79. doi: 10.1074/jbc.M116.744664. Epub 2016 Oct 7.

40.

CD36 Provides Host Protection Against Klebsiella pneumoniae Intrapulmonary Infection by Enhancing Lipopolysaccharide Responsiveness and Macrophage Phagocytosis.

Olonisakin TF, Li H, Xiong Z, Kochman EJ, Yu M, Qu Y, Hulver M, Kolls JK, St Croix C, Doi Y, Nguyen MH, Shanks RM, Mallampalli RK, Kagan VE, Ray A, Silverstein RL, Ray P, Lee JS.

J Infect Dis. 2016 Dec 15;214(12):1865-1875. Epub 2016 Sep 28.

41.

Imaging mass spectrometry reveals loss of polyunsaturated cardiolipins in the cortical contusion, hippocampus, and thalamus after traumatic brain injury.

Sparvero LJ, Amoscato AA, Fink AB, Anthonymuthu T, New LA, Kochanek PM, Watkins S, Kagan VE, Bayır H.

J Neurochem. 2016 Nov;139(4):659-675. doi: 10.1111/jnc.13840. Epub 2016 Sep 26.

42.

Known unknowns of cardiolipin signaling: The best is yet to come.

Maguire JJ, Tyurina YY, Mohammadyani D, Kapralov AA, Anthonymuthu TS, Qu F, Amoscato AA, Sparvero LJ, Tyurin VA, Planas-Iglesias J, He RR, Klein-Seetharaman J, Bayır H, Kagan VE.

Biochim Biophys Acta Mol Cell Biol Lipids. 2017 Jan;1862(1):8-24. doi: 10.1016/j.bbalip.2016.08.001. Epub 2016 Aug 4. Review.

43.

Gender differences in murine pulmonary responses elicited by cellulose nanocrystals.

Shvedova AA, Kisin ER, Yanamala N, Farcas MT, Menas AL, Williams A, Fournier PM, Reynolds JS, Gutkin DW, Star A, Reiner RS, Halappanavar S, Kagan VE.

Part Fibre Toxicol. 2016 Jun 8;13(1):28. doi: 10.1186/s12989-016-0140-x.

44.

Biosynthesis of oxidized lipid mediators via lipoprotein-associated phospholipase A2 hydrolysis of extracellular cardiolipin induces endothelial toxicity.

Buland JR, Wasserloos KJ, Tyurin VA, Tyurina YY, Amoscato AA, Mallampalli RK, Chen BB, Zhao J, Zhao Y, Ofori-Acquah S, Kagan VE, Pitt BR.

Am J Physiol Lung Cell Mol Physiol. 2016 Aug 1;311(2):L303-16. doi: 10.1152/ajplung.00038.2016. Epub 2016 May 27.

45.

Peroxidase activation of cytoglobin by anionic phospholipids: Mechanisms and consequences.

Tejero J, Kapralov AA, Baumgartner MP, Sparacino-Watkins CE, Anthonymutu TS, Vlasova II, Camacho CJ, Gladwin MT, Bayir H, Kagan VE.

Biochim Biophys Acta. 2016 May;1861(5):391-401. doi: 10.1016/j.bbalip.2016.02.022. Epub 2016 Feb 27.

46.

Mild mitochondrial metabolic deficits by α-ketoglutarate dehydrogenase inhibition cause prominent changes in intracellular autophagic signaling: Potential role in the pathobiology of Alzheimer's disease.

Banerjee K, Munshi S, Xu H, Frank DE, Chen HL, Chu CT, Yang J, Cho S, Kagan VE, Denton TT, Tyurina YY, Jiang JF, Gibson GE.

Neurochem Int. 2016 Jun;96:32-45. doi: 10.1016/j.neuint.2016.02.011. Epub 2016 Feb 23.

47.

Necrostatin-1 rescues mice from lethal irradiation.

Huang Z, Epperly M, Watkins SC, Greenberger JS, Kagan VE, Bayır H.

Biochim Biophys Acta. 2016 Apr;1862(4):850-856. doi: 10.1016/j.bbadis.2016.01.014. Epub 2016 Jan 20.

48.

Enzymatic oxidative biodegradation of nanoparticles: Mechanisms, significance and applications.

Vlasova II, Kapralov AA, Michael ZP, Burkert SC, Shurin MR, Star A, Shvedova AA, Kagan VE.

Toxicol Appl Pharmacol. 2016 May 15;299:58-69. doi: 10.1016/j.taap.2016.01.002. Epub 2016 Jan 6. Review.

49.

NDPK-D (NM23-H4)-mediated externalization of cardiolipin enables elimination of depolarized mitochondria by mitophagy.

Kagan VE, Jiang J, Huang Z, Tyurina YY, Desbourdes C, Cottet-Rousselle C, Dar HH, Verma M, Tyurin VA, Kapralov AA, Cheikhi A, Mao G, Stolz D, St Croix CM, Watkins S, Shen Z, Li Y, Greenberg ML, Tokarska-Schlattner M, Boissan M, Lacombe ML, Epand RM, Chu CT, Mallampalli RK, Bayır H, Schlattner U.

Cell Death Differ. 2016 Jul;23(7):1140-51. doi: 10.1038/cdd.2015.160. Epub 2016 Jan 8.

50.

Mitochondrial Redox Opto-Lipidomics Reveals Mono-Oxygenated Cardiolipins as Pro-Apoptotic Death Signals.

Mao G, Qu F, St Croix CM, Tyurina YY, Planas-Iglesias J, Jiang J, Huang Z, Amoscato AA, Tyurin VA, Kapralov AA, Cheikhi A, Maguire J, Klein-Seetharaman J, Bayır H, Kagan VE.

ACS Chem Biol. 2016 Feb 19;11(2):530-40. doi: 10.1021/acschembio.5b00737. Epub 2016 Jan 5.

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