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Items: 20

1.

Bacteremia in Childhood Life-Threatening Infections in Urban Gambia: EUCLIDS in West Africa.

Secka F, Herberg JA, Sarr I, Darboe S, Sey G, Saidykhan M, Wathuo M, Kaforou M, Antonio M, Roca A, Zaman SMA, Cebey-López M, Boeddha NP, Paulus S, Kohlfürst DS, Emonts M, Zenz W, Carrol ED, de Groot R, Schlapbach L, Martinon-Torres F, Bojang K, Levin M, van der Flier M, Anderson ST.

Open Forum Infect Dis. 2019 Jul 27;6(9):ofz332. doi: 10.1093/ofid/ofz332. eCollection 2019 Sep.

2.

Guidance for Studies Evaluating the Accuracy of Biomarker-Based Nonsputum Tests to Diagnose Tuberculosis.

Drain PK, Gardiner J, Hannah H, Broger T, Dheda K, Fielding K, Walzl G, Kaforou M, Kranzer K, Joosten SA, Gilpin C, Weyer K, Denkinger CM, Schumacher SG.

J Infect Dis. 2019 Oct 8;220(Supplement_3):S108-S115. doi: 10.1093/infdis/jiz356.

PMID:
31593598
3.

Cohort profile of the Biomarkers of Acute Serious Illness in Children (BASIC) study: a prospective multicentre cohort study in critically ill children.

Feinstein Y, Walker JC, Peters MJ, Nadel S, Pathan N, Edmonds N, Herberg J, Kaforou M, Wright V, Levin M, Ramnarayan P.

BMJ Open. 2018 Nov 8;8(11):e024729. doi: 10.1136/bmjopen-2018-024729.

4.

Whole Blood Gene Expression Reveals Specific Transcriptome Changes in Neonatal Encephalopathy.

Montaldo P, Kaforou M, Pollara G, Hervás-Marín D, Calabria I, Panadero J, Pedrola L, Lally PJ, Oliveira V, Kage A, Atreja G, Mendoza J, Soe A, Pattnayak S, Shankaran S, Vento M, Herberg J, Thayyil S.

Neonatology. 2019;115(1):68-76. doi: 10.1159/000492420. Epub 2018 Oct 10.

5.

Diagnosis of Kawasaki Disease Using a Minimal Whole-Blood Gene Expression Signature.

Wright VJ, Herberg JA, Kaforou M, Shimizu C, Eleftherohorinou H, Shailes H, Barendregt AM, Menikou S, Gormley S, Berk M, Hoang LT, Tremoulet AH, Kanegaye JT, Coin LJM, Glodé MP, Hibberd M, Kuijpers TW, Hoggart CJ, Burns JC, Levin M; Immunopathology of Respiratory, Inflammatory and Infectious Disease Study (IRIS) Consortium and the Pediatric Emergency Medicine Kawasaki Disease Research Group (PEMKDRG).

JAMA Pediatr. 2018 Oct 1;172(10):e182293. doi: 10.1001/jamapediatrics.2018.2293. Epub 2018 Oct 1.

6.

Childhood tuberculosis is associated with decreased abundance of T cell gene transcripts and impaired T cell function.

Hemingway C, Berk M, Anderson ST, Wright VJ, Hamilton S, Eleftherohorinou H, Kaforou M, Goldgof GM, Hickman K, Kampmann B, Schoeman J, Eley B, Beatty D, Pienaar S, Nicol MP, Griffiths MJ, Waddell SJ, Newton SM, Coin LJ, Relman DA, Montana G, Levin M.

PLoS One. 2017 Nov 15;12(11):e0185973. doi: 10.1371/journal.pone.0185973. eCollection 2017.

7.

Genome-wide host RNA signatures of infectious diseases: discovery and clinical translation.

Gliddon HD, Herberg JA, Levin M, Kaforou M.

Immunology. 2018 Feb;153(2):171-178. doi: 10.1111/imm.12841. Epub 2017 Oct 24. Review.

8.

Diagnosis of Bacterial Infection Using a 2-Transcript Host RNA Signature in Febrile Infants 60 Days or Younger.

Kaforou M, Herberg JA, Wright VJ, Coin LJM, Levin M.

JAMA. 2017 Apr 18;317(15):1577-1578. doi: 10.1001/jama.2017.1365. No abstract available.

9.

A Simple Screening Approach To Prioritize Genes for Functional Analysis Identifies a Role for Interferon Regulatory Factor 7 in the Control of Respiratory Syncytial Virus Disease.

McDonald JU, Kaforou M, Clare S, Hale C, Ivanova M, Huntley D, Dorner M, Wright VJ, Levin M, Martinon-Torres F, Herberg JA, Tregoning JS.

mSystems. 2016 Jun 28;1(3). pii: e00051-16. eCollection 2016 May-Jun.

10.

Diagnostic Test Accuracy of a 2-Transcript Host RNA Signature for Discriminating Bacterial vs Viral Infection in Febrile Children.

Herberg JA, Kaforou M, Wright VJ, Shailes H, Eleftherohorinou H, Hoggart CJ, Cebey-López M, Carter MJ, Janes VA, Gormley S, Shimizu C, Tremoulet AH, Barendregt AM, Salas A, Kanegaye J, Pollard AJ, Faust SN, Patel S, Kuijpers T, Martinón-Torres F, Burns JC, Coin LJ, Levin M; IRIS Consortium.

JAMA. 2016 Aug 23-30;316(8):835-45. doi: 10.1001/jama.2016.11236. Erratum in: JAMA. 2017 Feb 7;317(5):538.

11.

A nucleic acid strand displacement system for the multiplexed detection of tuberculosis-specific mRNA using quantum dots.

Gliddon HD, Howes PD, Kaforou M, Levin M, Stevens MM.

Nanoscale. 2016 May 21;8(19):10087-95. doi: 10.1039/c6nr00484a. Epub 2016 Apr 18.

12.

Predicting active tuberculosis progression by RNA analysis.

Levin M, Kaforou M.

Lancet. 2016 Jun 4;387(10035):2268-2270. doi: 10.1016/S0140-6736(16)00165-3. Epub 2016 Mar 24. No abstract available.

PMID:
27017311
13.

Understanding immune protection against tuberculosis using RNA expression profiling.

von Both U, Kaforou M, Levin M, Newton SM.

Vaccine. 2015 Sep 29;33(40):5289-93. doi: 10.1016/j.vaccine.2015.05.025. Epub 2015 May 23. Review.

14.

Host RNA signatures for diagnostics: an example from paediatric tuberculosis in Africa.

Kaforou M, Wright VJ, Levin M.

J Infect. 2014 Nov;69 Suppl 1:S28-31. doi: 10.1016/j.jinf.2014.08.006. Epub 2014 Sep 26. Review.

PMID:
25264160
15.

Diagnosis of childhood tuberculosis and host RNA expression in Africa.

Anderson ST, Kaforou M, Brent AJ, Wright VJ, Banwell CM, Chagaluka G, Crampin AC, Dockrell HM, French N, Hamilton MS, Hibberd ML, Kern F, Langford PR, Ling L, Mlotha R, Ottenhoff THM, Pienaar S, Pillay V, Scott JAG, Twahir H, Wilkinson RJ, Coin LJ, Heyderman RS, Levin M, Eley B.

N Engl J Med. 2014 May 1;370(18):1712-1723. doi: 10.1056/NEJMoa1303657.

16.

Brown and white adipose tissues: intrinsic differences in gene expression and response to cold exposure in mice.

Rosell M, Kaforou M, Frontini A, Okolo A, Chan YW, Nikolopoulou E, Millership S, Fenech ME, MacIntyre D, Turner JO, Moore JD, Blackburn E, Gullick WJ, Cinti S, Montana G, Parker MG, Christian M.

Am J Physiol Endocrinol Metab. 2014 Apr 15;306(8):E945-64. doi: 10.1152/ajpendo.00473.2013. Epub 2014 Feb 18.

17.

RIP140 represses the "brown-in-white" adipocyte program including a futile cycle of triacylglycerol breakdown and synthesis.

Kiskinis E, Chatzeli L, Curry E, Kaforou M, Frontini A, Cinti S, Montana G, Parker MG, Christian M.

Mol Endocrinol. 2014 Mar;28(3):344-56. doi: 10.1210/me.2013-1254. Epub 2014 Jan 30.

18.

Detection of tuberculosis in HIV-infected and -uninfected African adults using whole blood RNA expression signatures: a case-control study.

Kaforou M, Wright VJ, Oni T, French N, Anderson ST, Bangani N, Banwell CM, Brent AJ, Crampin AC, Dockrell HM, Eley B, Heyderman RS, Hibberd ML, Kern F, Langford PR, Ling L, Mendelson M, Ottenhoff TH, Zgambo F, Wilkinson RJ, Coin LJ, Levin M.

PLoS Med. 2013 Oct;10(10):e1001538. doi: 10.1371/journal.pmed.1001538. Epub 2013 Oct 22.

19.

Transcriptomic profiling in childhood H1N1/09 influenza reveals reduced expression of protein synthesis genes.

Herberg JA, Kaforou M, Gormley S, Sumner ER, Patel S, Jones KD, Paulus S, Fink C, Martinon-Torres F, Montana G, Wright VJ, Levin M.

J Infect Dis. 2013 Nov 15;208(10):1664-8. doi: 10.1093/infdis/jit348. Epub 2013 Jul 29.

20.

Bioinformatics: living on the edge.

Bellos E, Coin LJ, Kaforou M.

Genome Biol. 2012 Oct 26;13(10):321. doi: 10.1186/gb-2012-13-10-321.

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