Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 177

1.

Coumarin Reduces Virulence and Biofilm Formation in Pseudomonas aeruginosa by Affecting Quorum Sensing, Type III Secretion and C-di-GMP Levels.

Zhang Y, Sass A, Van Acker H, Wille J, Verhasselt B, Van Nieuwerburgh F, Kaever V, Crabbé A, Coenye T.

Front Microbiol. 2018 Aug 21;9:1952. doi: 10.3389/fmicb.2018.01952. eCollection 2018.

2.

Seven-transmembrane receptor protein RgsP and cell wall-binding protein RgsM promote unipolar growth in Rhizobiales.

Schäper S, Yau HCL, Krol E, Skotnicka D, Heimerl T, Gray J, Kaever V, Søgaard-Andersen L, Vollmer W, Becker A.

PLoS Genet. 2018 Aug 13;14(8):e1007594. doi: 10.1371/journal.pgen.1007594. eCollection 2018 Aug.

3.

cUMP hydrolysis by PDE3B.

Ostermeyer J, Golly F, Kaever V, Dove S, Seifert R, Schneider EH.

Naunyn Schmiedebergs Arch Pharmacol. 2018 Sep;391(9):891-905. doi: 10.1007/s00210-018-1512-6. Epub 2018 May 28.

PMID:
29808231
4.

The Pseudomonas aeruginosa ExoY phenotype of high-copy-number recombinants is not detectable in natural isolates.

Munder A, Rothschuh J, Schirmer B, Klockgether J, Kaever V, Tümmler B, Seifert R, Kloth C.

Open Biol. 2018 Jan;8(1). pii: 170250. doi: 10.1098/rsob.170250.

5.

Mass-spectrometric profiling of cerebrospinal fluid reveals metabolite biomarkers for CNS involvement in varicella zoster virus reactivation.

Kuhn M, Sühs KW, Akmatov MK, Klawonn F, Wang J, Skripuletz T, Kaever V, Stangel M, Pessler F.

J Neuroinflammation. 2018 Jan 17;15(1):20. doi: 10.1186/s12974-017-1041-0.

6.

More than Enzymes That Make or Break Cyclic Di-GMP-Local Signaling in the Interactome of GGDEF/EAL Domain Proteins of Escherichia coli.

Sarenko O, Klauck G, Wilke FM, Pfiffer V, Richter AM, Herbst S, Kaever V, Hengge R.

MBio. 2017 Oct 10;8(5). pii: e01639-17. doi: 10.1128/mBio.01639-17.

7.

BolA Is Required for the Accurate Regulation of c-di-GMP, a Central Player in Biofilm Formation.

Moreira RN, Dressaire C, Barahona S, Galego L, Kaever V, Jenal U, Arraiano CM.

MBio. 2017 Sep 19;8(5). pii: e00443-17. doi: 10.1128/mBio.00443-17.

8.

Identification and Quantification of Cyclic Di-Guanosine Monophosphate and Its Linear Metabolites by Reversed-Phase LC-MS/MS.

Bähre H, Kaever V.

Methods Mol Biol. 2017;1657:45-58. doi: 10.1007/978-1-4939-7240-1_5.

PMID:
28889285
9.

cGAMP Quantification in Virus-Infected Human Monocyte-Derived Cells by HPLC-Coupled Tandem Mass Spectrometry.

Paijo J, Kaever V, Kalinke U.

Methods Mol Biol. 2017;1656:153-166. doi: 10.1007/978-1-4939-7237-1_9.

PMID:
28808968
10.

Identification of the Components Involved in Cyclic Di-AMP Signaling in Mycoplasma pneumoniae.

Blötz C, Treffon K, Kaever V, Schwede F, Hammer E, Stülke J.

Front Microbiol. 2017 Jul 13;8:1328. doi: 10.3389/fmicb.2017.01328. eCollection 2017.

11.

The protein Slr1143 is an active diguanylate cyclase in Synechocystis sp. PCC 6803 and interacts with the photoreceptor Cph2.

Angerer V, Schwenk P, Wallner T, Kaever V, Hiltbrunner A, Wilde A.

Microbiology. 2017 Jun;163(6):920-930. doi: 10.1099/mic.0.000475. Epub 2017 Jun 21.

PMID:
28635593
12.

High intracellular c-di-GMP levels antagonize quorum sensing and virulence gene expression in Burkholderia cenocepacia H111.

Schmid N, Suppiger A, Steiner E, Pessi G, Kaever V, Fazli M, Tolker-Nielsen T, Jenal U, Eberl L.

Microbiology. 2017 May;163(5):754-764. doi: 10.1099/mic.0.000452. Epub 2017 May 3.

PMID:
28463102
13.

Control of potassium homeostasis is an essential function of the second messenger cyclic di-AMP in Bacillus subtilis.

Gundlach J, Herzberg C, Kaever V, Gunka K, Hoffmann T, Weiß M, Gibhardt J, Thürmer A, Hertel D, Daniel R, Bremer E, Commichau FM, Stülke J.

Sci Signal. 2017 Apr 18;10(475). pii: eaal3011. doi: 10.1126/scisignal.aal3011.

PMID:
28420751
14.

Regulation of Burkholderia cenocepacia biofilm formation by RpoN and the c-di-GMP effector BerB.

Fazli M, Rybtke M, Steiner E, Weidel E, Berthelsen J, Groizeleau J, Bin W, Zhi BZ, Yaming Z, Kaever V, Givskov M, Hartmann RW, Eberl L, Tolker-Nielsen T.

Microbiologyopen. 2017 Aug;6(4). doi: 10.1002/mbo3.480. Epub 2017 Apr 16.

15.

Sialylation Is Dispensable for Early Murine Embryonic Development in Vitro.

Abeln M, Borst KM, Cajic S, Thiesler H, Kats E, Albers I, Kuhn M, Kaever V, Rapp E, Münster-Kühnel A, Weinhold B.

Chembiochem. 2017 Jul 4;18(13):1305-1316. doi: 10.1002/cbic.201700083. Epub 2017 May 11.

16.

Cohesive Properties of the Caulobacter crescentus Holdfast Adhesin Are Regulated by a Novel c-di-GMP Effector Protein.

Sprecher KS, Hug I, Nesper J, Potthoff E, Mahi MA, Sangermani M, Kaever V, Schwede T, Vorholt J, Jenal U.

MBio. 2017 Mar 21;8(2). pii: e00294-17. doi: 10.1128/mBio.00294-17.

17.

Analytical Methods for the Quantification of Histamine and Histamine Metabolites.

Bähre H, Kaever V.

Handb Exp Pharmacol. 2017;241:3-19. doi: 10.1007/164_2017_22. Review.

PMID:
28321587
18.

Identification of a Pseudomonas aeruginosa PAO1 DNA Methyltransferase, Its Targets, and Physiological Roles.

Doberenz S, Eckweiler D, Reichert O, Jensen V, Bunk B, Spröer C, Kordes A, Frangipani E, Luong K, Korlach J, Heeb S, Overmann J, Kaever V, Häussler S.

MBio. 2017 Feb 21;8(1). pii: e02312-16. doi: 10.1128/mBio.02312-16.

19.

Mass Spectrometric Analysis of Non-canonical Cyclic Nucleotides.

Bähre H, Kaever V.

Handb Exp Pharmacol. 2017;238:293-306. doi: 10.1007/164_2016_5001. Review.

PMID:
28181004
20.

cUMP hydrolysis by PDE3A.

Berrisch S, Ostermeyer J, Kaever V, Kälble S, Hilfiker-Kleiner D, Seifert R, Schneider EH.

Naunyn Schmiedebergs Arch Pharmacol. 2017 Mar;390(3):269-280. doi: 10.1007/s00210-016-1328-1. Epub 2016 Dec 14.

PMID:
27975297
21.

Evolutionary Adaptation of the Essential tRNA Methyltransferase TrmD to the Signaling Molecule 3',5'-cAMP in Bacteria.

Zhang Y, Agrebi R, Bellows LE, Collet JF, Kaever V, Gründling A.

J Biol Chem. 2017 Jan 6;292(1):313-327. doi: 10.1074/jbc.M116.758896. Epub 2016 Nov 23.

22.

New Insights into the Cyclic Di-adenosine Monophosphate (c-di-AMP) Degradation Pathway and the Requirement of the Cyclic Dinucleotide for Acid Stress Resistance in Staphylococcus aureus.

Bowman L, Zeden MS, Schuster CF, Kaever V, Gründling A.

J Biol Chem. 2016 Dec 30;291(53):26970-26986. doi: 10.1074/jbc.M116.747709. Epub 2016 Nov 10.

23.

Cyclic mononucleotide- and Clr-dependent gene regulation in Sinorhizobium meliloti.

Krol E, Klaner C, Gnau P, Kaever V, Essen LO, Becker A.

Microbiology. 2016 Oct;162(10):1840-1856. doi: 10.1099/mic.0.000356. Epub 2016 Aug 16.

PMID:
27535558
24.

The anti-cancerous drug doxorubicin decreases the c-di-GMP content in Pseudomonas aeruginosa but promotes biofilm formation.

Groizeleau J, Rybtke M, Andersen JB, Berthelsen J, Liu Y, Yang L, Nielsen TE, Kaever V, Givskov M, Tolker-Nielsen T.

Microbiology. 2016 Oct;162(10):1797-1807. doi: 10.1099/mic.0.000354. Epub 2016 Aug 15.

PMID:
27526691
25.

The Cell Wall Polymer Lipoteichoic Acid Becomes Nonessential in Staphylococcus aureus Cells Lacking the ClpX Chaperone.

Bæk KT, Bowman L, Millership C, Dupont Søgaard M, Kaever V, Siljamäki P, Savijoki K, Varmanen P, Nyman TA, Gründling A, Frees D.

MBio. 2016 Aug 9;7(4). pii: e01228-16. doi: 10.1128/mBio.01228-16.

26.

Evidence for Escherichia coli Diguanylate Cyclase DgcZ Interlinking Surface Sensing and Adhesion via Multiple Regulatory Routes.

Lacanna E, Bigosch C, Kaever V, Boehm A, Becker A.

J Bacteriol. 2016 Aug 25;198(18):2524-35. doi: 10.1128/JB.00320-16. Print 2016 Sep 15.

27.

Impaired glyoxalase activity is associated with reduced expression of neurotrophic factors and pro-inflammatory processes in diabetic skin cells.

Reichert O, Fleming T, Neufang G, Schmelz M, Genth H, Kaever V, Wenck H, Stäb F, Terstegen L, Kolbe L, Roggenkamp D.

Exp Dermatol. 2017 Jan;26(1):44-50. doi: 10.1111/exd.13118.

PMID:
27306297
28.

Non-targeted metabolomics by high resolution mass spectrometry in HPRT knockout mice.

Tschirner SK, Bähre H, Kaever A, Schneider EH, Seifert R, Kaever V.

Life Sci. 2016 Jul 1;156:68-73. doi: 10.1016/j.lfs.2016.05.031. Epub 2016 May 21.

PMID:
27221022
29.

A Minimal Threshold of c-di-GMP Is Essential for Fruiting Body Formation and Sporulation in Myxococcus xanthus.

Skotnicka D, Smaldone GT, Petters T, Trampari E, Liang J, Kaever V, Malone JG, Singer M, Søgaard-Andersen L.

PLoS Genet. 2016 May 23;12(5):e1006080. doi: 10.1371/journal.pgen.1006080. eCollection 2016 May.

30.

Neurotransmitter and their metabolite concentrations in different areas of the HPRT knockout mouse brain.

Tschirner SK, Gutzki F, Schneider EH, Seifert R, Kaever V.

J Neurol Sci. 2016 Jun 15;365:169-74. doi: 10.1016/j.jns.2016.04.025. Epub 2016 Apr 16.

PMID:
27206901
31.

cGAS Senses Human Cytomegalovirus and Induces Type I Interferon Responses in Human Monocyte-Derived Cells.

Paijo J, Döring M, Spanier J, Grabski E, Nooruzzaman M, Schmidt T, Witte G, Messerle M, Hornung V, Kaever V, Kalinke U.

PLoS Pathog. 2016 Apr 8;12(4):e1005546. doi: 10.1371/journal.ppat.1005546. eCollection 2016 Apr.

32.

Corrigendum: Systemic Induction of NO-, Redox-, and cGMP Signaling in the Pumpkin Extrafascicular Phloem upon Local Leaf Wounding.

Gaupels F, Furch AC, Zimmermann MR, Chen F, Kaever V, Buhtz A, Kehr J, Sarioglu H, Kogel KH, Durner J.

Front Plant Sci. 2016 Mar 7;7:281. doi: 10.3389/fpls.2016.00281. eCollection 2016.

33.

Systemic Induction of NO-, Redox-, and cGMP Signaling in the Pumpkin Extrafascicular Phloem upon Local Leaf Wounding.

Gaupels F, Furch AC, Zimmermann MR, Chen F, Kaever V, Buhtz A, Kehr J, Sarioglu H, Kogel KH, Durner J.

Front Plant Sci. 2016 Feb 12;7:154. doi: 10.3389/fpls.2016.00154. eCollection 2016. Erratum in: Front Plant Sci. 2016;7:281.

34.

GTPase domain driven dimerization of SEPT7 is dispensable for the critical role of septins in fibroblast cytokinesis.

Abbey M, Hakim C, Anand R, Lafera J, Schambach A, Kispert A, Taft MH, Kaever V, Kotlyarov A, Gaestel M, Menon MB.

Sci Rep. 2016 Jan 28;6:20007. doi: 10.1038/srep20007.

35.

Oxygen-dependent regulation of c-di-GMP synthesis by SadC controls alginate production in Pseudomonas aeruginosa.

Schmidt A, Hammerbacher AS, Bastian M, Nieken KJ, Klockgether J, Merighi M, Lapouge K, Poschgan C, Kölle J, Acharya KR, Ulrich M, Tümmler B, Unden G, Kaever V, Lory S, Haas D, Schwarz S, Döring G.

Environ Microbiol. 2016 Oct;18(10):3390-3402. doi: 10.1111/1462-2920.13208. Epub 2016 Feb 4.

PMID:
26743546
36.

The DSF type quorum sensing signalling system RpfF/R regulates diverse phenotypes in the opportunistic pathogen Cronobacter.

Suppiger A, Eshwar AK, Stephan R, Kaever V, Eberl L, Lehner A.

Sci Rep. 2016 Jan 4;6:18753. doi: 10.1038/srep18753.

37.

Augmentation of Transient Donor Cell Chimerism and Alloantigen-Specific Regulation of Lung Transplants in Miniature Swine.

Avsar M, Jansson K, Sommer W, Kruse B, Thissen S, Dreckmann K, Knoefel AK, Salman J, Hafer C, Hecker J, Buechler G, Karstens JH, Jonigk D, Länger F, Kaever V, Falk CS, Hewicker-Trautwein M, Ungefroren H, Haverich A, Strüber M, Warnecke G.

Am J Transplant. 2016 May;16(5):1371-82. doi: 10.1111/ajt.13629. Epub 2016 Feb 22.

38.

Cyclic Di-GMP Regulates Multiple Cellular Functions in the Symbiotic Alphaproteobacterium Sinorhizobium meliloti.

Schäper S, Krol E, Skotnicka D, Kaever V, Hilker R, Søgaard-Andersen L, Becker A.

J Bacteriol. 2015 Nov 16;198(3):521-35. doi: 10.1128/JB.00795-15. Print 2016 Feb 1.

39.

Temporal and organ-specific detection of cNMPs including cUMP in the zebrafish.

Dittmar F, Abdelilah-Seyfried S, Tschirner SK, Kaever V, Seifert R.

Biochem Biophys Res Commun. 2015 Dec 25;468(4):708-12. doi: 10.1016/j.bbrc.2015.11.020. Epub 2015 Nov 6.

PMID:
26551461
40.

Phenotypes Associated with the Essential Diadenylate Cyclase CdaA and Its Potential Regulator CdaR in the Human Pathogen Listeria monocytogenes.

Rismondo J, Gibhardt J, Rosenberg J, Kaever V, Halbedel S, Commichau FM.

J Bacteriol. 2015 Nov 2;198(3):416-26. doi: 10.1128/JB.00845-15. Print 2016 Feb 1.

41.

Novel genetic tools to tackle c-di-GMP-dependent signalling in Pseudomonas aeruginosa.

Pawar SV, Messina M, Rinaldo S, Cutruzzolà F, Kaever V, Rampioni G, Leoni L.

J Appl Microbiol. 2016 Jan;120(1):205-17. doi: 10.1111/jam.12984.

PMID:
26497534
42.

Altered histamine neurotransmission in HPRT-deficient mice.

Tschirner SK, Gutzki F, Kaever V, Seifert R, Schneider EH.

Neurosci Lett. 2015 Nov 16;609:74-80. doi: 10.1016/j.neulet.2015.10.011. Epub 2015 Oct 19.

PMID:
26453761
43.

Heterogeneity of pulmonary endothelial cyclic nucleotide response to Pseudomonas aeruginosa ExoY infection.

Morrow KA, Seifert R, Kaever V, Britain AL, Sayner SL, Ochoa CD, Cioffi EA, Frank DW, Rich TC, Stevens T.

Am J Physiol Lung Cell Mol Physiol. 2015 Nov 15;309(10):L1199-207. doi: 10.1152/ajplung.00165.2015. Epub 2015 Sep 18.

44.

Cell aggregation promotes pyoverdine-dependent iron uptake and virulence in Pseudomonas aeruginosa.

Visaggio D, Pasqua M, Bonchi C, Kaever V, Visca P, Imperi F.

Front Microbiol. 2015 Aug 28;6:902. doi: 10.3389/fmicb.2015.00902. eCollection 2015.

45.

Oligoribonuclease is a central feature of cyclic diguanylate signaling in Pseudomonas aeruginosa.

Cohen D, Mechold U, Nevenzal H, Yarmiyhu Y, Randall TE, Bay DC, Rich JD, Parsek MR, Kaever V, Harrison JJ, Banin E.

Proc Natl Acad Sci U S A. 2015 Sep 8;112(36):11359-64. doi: 10.1073/pnas.1421450112. Epub 2015 Aug 24.

46.

Cyclic diGMP regulates production of sortase substrates of Clostridium difficile and their surface exposure through ZmpI protease-mediated cleavage.

Peltier J, Shaw HA, Couchman EC, Dawson LF, Yu L, Choudhary JS, Kaever V, Wren BW, Fairweather NF.

J Biol Chem. 2015 Oct 2;290(40):24453-69. doi: 10.1074/jbc.M115.665091. Epub 2015 Aug 17.

47.

An Essential Poison: Synthesis and Degradation of Cyclic Di-AMP in Bacillus subtilis.

Gundlach J, Mehne FM, Herzberg C, Kampf J, Valerius O, Kaever V, Stülke J.

J Bacteriol. 2015 Oct;197(20):3265-74. doi: 10.1128/JB.00564-15. Epub 2015 Aug 3.

48.

Viruses transfer the antiviral second messenger cGAMP between cells.

Bridgeman A, Maelfait J, Davenne T, Partridge T, Peng Y, Mayer A, Dong T, Kaever V, Borrow P, Rehwinkel J.

Science. 2015 Sep 11;349(6253):1228-32. doi: 10.1126/science.aab3632. Epub 2015 Jul 30.

49.

Cyclic Di-GMP Regulates Type IV Pilus-Dependent Motility in Myxococcus xanthus.

Skotnicka D, Petters T, Heering J, Hoppert M, Kaever V, Søgaard-Andersen L.

J Bacteriol. 2015 Jun 29;198(1):77-90. doi: 10.1128/JB.00281-15. Print 2016 Jan 1.

50.

Deoxycytidine-kinase knockdown as a novel myeloprotective strategy in the context of fludarabine, cytarabine or cladribine therapy.

Lachmann N, Czarnecki K, Brennig S, Phaltane R, Heise M, Heinz N, Kempf H, Dilloo D, Kaever V, Schambach A, Heuser M, Moritz T.

Leukemia. 2015 Nov;29(11):2266-9. doi: 10.1038/leu.2015.108. Epub 2015 Apr 29. No abstract available.

PMID:
25921248

Supplemental Content

Loading ...
Support Center