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Correction: Cross-sectional focusing of red blood cells in a constricted microfluidic channel.

Abay A, Recktenwald SM, John T, Kaestner L, Wagner C.

Soft Matter. 2020 Feb 19;16(7):1941. doi: 10.1039/d0sm90025g.


Intracellular Ca2+ Concentration and Phosphatidylserine Exposure in Healthy Human Erythrocytes in Dependence on in vivo Cell Age.

Bernhardt I, Nguyen DB, Wesseling MC, Kaestner L.

Front Physiol. 2020 Jan 10;10:1629. doi: 10.3389/fphys.2019.01629. eCollection 2019. Review.


Cross-sectional focusing of red blood cells in a constricted microfluidic channel.

Abay A, Recktenwald SM, John T, Kaestner L, Wagner C.

Soft Matter. 2020 Jan 2;16(2):534-543. doi: 10.1039/c9sm01740b. Erratum in: Soft Matter. 2020 Feb 10;:.


Calcium Channels and Calcium-Regulated Channels in Human Red Blood Cells.

Kaestner L, Bogdanova A, Egee S.

Adv Exp Med Biol. 2020;1131:625-648. doi: 10.1007/978-3-030-12457-1_25. Review.


Large scale, unbiased analysis of elementary calcium signaling events in cardiac myocytes.

Tian Q, Schröder L, Schwarz Y, Flockerzi A, Kaestner L, Zeug A, Bruns D, Lipp P.

J Mol Cell Cardiol. 2019 Oct;135:79-89. doi: 10.1016/j.yjmcc.2019.08.004. Epub 2019 Aug 13.


Red Blood Cells: Chasing Interactions.

Pretini V, Koenen MH, Kaestner L, Fens MHAM, Schiffelers RM, Bartels M, Van Wijk R.

Front Physiol. 2019 Jul 31;10:945. doi: 10.3389/fphys.2019.00945. eCollection 2019. Review.


The Evolution of Erythrocytes Becoming Red in Respect to Fluorescence.

Hertz L, Ruppenthal S, Simionato G, Quint S, Kihm A, Abay A, Petkova-Kirova P, Boehm U, Weissgerber P, Wagner C, Laschke MW, Kaestner L.

Front Physiol. 2019 Jun 19;10:753. doi: 10.3389/fphys.2019.00753. eCollection 2019.


Density, heterogeneity and deformability of red cells as markers of clinical severity in hereditary spherocytosis.

Huisjes R, Makhro A, Llaudet-Planas E, Hertz L, Petkova-Kirova P, Verhagen LP, Pignatelli S, Rab MAE, Schiffelers RM, Seiler E, van Solinge WW, Corrons JV, Kaestner L, Mañú-Pereira M, Bogdanov A, van Wijk R.

Haematologica. 2020 Jan 31;105(2):338-347. doi: 10.3324/haematol.2018.188151. Print 2020.


Glutaraldehyde - A Subtle Tool in the Investigation of Healthy and Pathologic Red Blood Cells.

Abay A, Simionato G, Chachanidze R, Bogdanova A, Hertz L, Bianchi P, van den Akker E, von Lindern M, Leonetti M, Minetti G, Wagner C, Kaestner L.

Front Physiol. 2019 May 14;10:514. doi: 10.3389/fphys.2019.00514. eCollection 2019.


Red Blood Cell Membrane Conductance in Hereditary Haemolytic Anaemias.

Petkova-Kirova P, Hertz L, Danielczok J, Huisjes R, Makhro A, Bogdanova A, Mañú-Pereira MDM, Vives Corrons JL, van Wijk R, Kaestner L.

Front Physiol. 2019 Apr 16;10:386. doi: 10.3389/fphys.2019.00386. eCollection 2019.


A Previously Unrecognized Ca2+-inhibited Nonselective Cation Channel in Red Blood Cells.

Petkova-Kirova P, Hertz L, Makhro A, Danielczok J, Huisjes R, Llaudet-Planas E, Mañú-Pereira MDM, Vives Corrons JL, van Wijk R, Bogdanova A, Kaestner L.

Hemasphere. 2018 Oct;2(5):e146. doi: 10.1097/HS9.0000000000000146. Epub 2018 Oct 2.


Commentary: Voltage Gating of Mechanosensitive PIEZO Channels.

Kaestner L, Egee S.

Front Physiol. 2018 Nov 20;9:1565. doi: 10.3389/fphys.2018.01565. eCollection 2018. No abstract available.


Editorial: The Red Cell Life-Cycle From Erythropoiesis to Clearance.

Kaestner L, Bogdanova A.

Front Physiol. 2018 Nov 8;9:1537. doi: 10.3389/fphys.2018.01537. eCollection 2018. No abstract available.


DREADD technology reveals major impact of Gq signalling on cardiac electrophysiology.

Kaiser E, Tian Q, Wagner M, Barth M, Xian W, Schröder L, Ruppenthal S, Kaestner L, Boehm U, Wartenberg P, Lu H, McMillin SM, Bone DBJ, Wess J, Lipp P.

Cardiovasc Res. 2019 May 1;115(6):1052-1066. doi: 10.1093/cvr/cvy251.


A novel gain-of-function mutation of Piezo1 is functionally affirmed in red blood cells by high-throughput patch clamp.

Rotordam MG, Fermo E, Becker N, Barcellini W, Brüggemann A, Fertig N, Egée S, Rapedius M, Bianchi P, Kaestner L.

Haematologica. 2019 May;104(5):e179-e183. doi: 10.3324/haematol.2018.201160. Epub 2018 Sep 20. No abstract available.


Management of urological injury at the time of urogynaecology surgery.

Kaestner L.

Best Pract Res Clin Obstet Gynaecol. 2019 Jan;54:2-11. doi: 10.1016/j.bpobgyn.2018.06.007. Epub 2018 Jun 28. Review.


Antimargination of Microparticles and Platelets in the Vicinity of Branching Vessels.

Bächer C, Kihm A, Schrack L, Kaestner L, Laschke MW, Wagner C, Gekle S.

Biophys J. 2018 Jul 17;115(2):411-425. doi: 10.1016/j.bpj.2018.06.013.


Investigating racial differences in clinical and pathological features of prostate cancer in South African men.

Dewar M, Kaestner L, Zikhali Q, Jehle K, Sinha S, Lazarus J.

S Afr J Surg. 2018 Jun;56(2):54-58.


Outcomes of outpatient ureteral stenting without fluoroscopy at Groote Schuur Hospital, Cape Town, South Africa.

Sinha S, Jaumdally SZ, Cassim F, Wicht J, Kaestner L, Panackal A, Jehle CH, Govender P, De Jager S, De Wet E, Dewar M, Kolia ME, Salukazana S, Moolman C, Van den Heever AP, Kowlessur B, Pinto G, Lazarus J.

S Afr Med J. 2018 May 25;108(6):506-510. doi: 10.7196/SAMJ.2018.v108i6.12983.


Squeezing for Life - Properties of Red Blood Cell Deformability.

Huisjes R, Bogdanova A, van Solinge WW, Schiffelers RM, Kaestner L, van Wijk R.

Front Physiol. 2018 Jun 1;9:656. doi: 10.3389/fphys.2018.00656. eCollection 2018. Review.


Classification of red blood cell shapes in flow using outlier tolerant machine learning.

Kihm A, Kaestner L, Wagner C, Quint S.

PLoS Comput Biol. 2018 Jun 15;14(6):e1006278. doi: 10.1371/journal.pcbi.1006278. eCollection 2018 Jun.


The Red Blood Cells on the Move!

Bogdanova A, Kaestner L.

Front Physiol. 2018 May 1;9:474. doi: 10.3389/fphys.2018.00474. eCollection 2018. No abstract available.


Voltage-Activated Ion Channels in Non-excitable Cells-A Viewpoint Regarding Their Physiological Justification.

Kaestner L, Wang X, Hertz L, Bernhardt I.

Front Physiol. 2018 Apr 27;9:450. doi: 10.3389/fphys.2018.00450. eCollection 2018. No abstract available.


Red Blood Cell Passage of Small Capillaries Is Associated with Transient Ca2+-mediated Adaptations.

Danielczok JG, Terriac E, Hertz L, Petkova-Kirova P, Lautenschläger F, Laschke MW, Kaestner L.

Front Physiol. 2017 Dec 5;8:979. doi: 10.3389/fphys.2017.00979. eCollection 2017.


NMDA Receptor Activity in Circulating Red Blood Cells: Methods of Detection.

Makhro A, Kaestner L, Bogdanova A.

Methods Mol Biol. 2017;1677:265-282. doi: 10.1007/978-1-4939-7321-7_15.


Is Increased Intracellular Calcium in Red Blood Cells a Common Component in the Molecular Mechanism Causing Anemia?

Hertz L, Huisjes R, Llaudet-Planas E, Petkova-Kirova P, Makhro A, Danielczok JG, Egee S, Del Mar Mañú-Pereira M, van Wijk R, Vives Corrons JL, Bogdanova A, Kaestner L.

Front Physiol. 2017 Sep 6;8:673. doi: 10.3389/fphys.2017.00673. eCollection 2017.


The buckling instability of aggregating red blood cells.

Flormann D, Aouane O, Kaestner L, Ruloff C, Misbah C, Podgorski T, Wagner C.

Sci Rep. 2017 Aug 11;7(1):7928. doi: 10.1038/s41598-017-07634-6.


Trifluoperazine-Induced Suicidal Erythrocyte Death and S-Nitrosylation Inhibition, Reversed by the Nitric Oxide Donor Sodium Nitroprusside.

Ghashghaeinia M, Wesseling MC, Ramos E, Petkova-Kirova P, Waibel S, Lang E, Bissinger R, Alzoubi K, Edelmann B, Hosseinzadeh Z, Dreischer P, Shahvaroughi-Farahani A, Mrowietz U, Köberle M, Kaestner L, Bernhardt I, Martínez-Ruiz A, Wieder T, Lang F.

Cell Physiol Biochem. 2017;42(5):1985-1998. doi: 10.1159/000479838. Epub 2017 Aug 9.


The potential of erythrocytes as cellular aging models.

Kaestner L, Minetti G.

Cell Death Differ. 2017 Sep;24(9):1475-1477. doi: 10.1038/cdd.2017.100. Epub 2017 Jun 16. No abstract available.


'Gardos Channelopathy': a variant of hereditary Stomatocytosis with complex molecular regulation.

Fermo E, Bogdanova A, Petkova-Kirova P, Zaninoni A, Marcello AP, Makhro A, Hänggi P, Hertz L, Danielczok J, Vercellati C, Mirra N, Zanella A, Cortelezzi A, Barcellini W, Kaestner L, Bianchi P.

Sci Rep. 2017 May 11;7(1):1744. doi: 10.1038/s41598-017-01591-w.


PKCα diffusion and translocation are independent of an intact cytoskeleton.

Hui X, Sauer B, Kaestner L, Kruse K, Lipp P.

Sci Rep. 2017 Mar 28;7(1):475. doi: 10.1038/s41598-017-00560-7.


Does Erythropoietin Regulate TRPC Channels in Red Blood Cells?

Danielczok J, Hertz L, Ruppenthal S, Kaiser E, Petkova-Kirova P, Bogdanova A, Krause E, Lipp P, Freichel M, Kaestner L, Birnbaumer L.

Cell Physiol Biochem. 2017;41(3):1219-1228. doi: 10.1159/000464384. Epub 2017 Mar 6.


The Molecular Structure of Human Red Blood Cell Membranes from Highly Oriented, Solid Supported Multi-Lamellar Membranes.

Himbert S, Alsop RJ, Rose M, Hertz L, Dhaliwal A, Moran-Mirabal JM, Verschoor CP, Bowdish DM, Kaestner L, Wagner C, Rheinstädter MC.

Sci Rep. 2017 Jan 3;7:39661. doi: 10.1038/srep39661.


C2-domain mediated nano-cluster formation increases calcium signaling efficiency.

Bonny M, Hui X, Schweizer J, Kaestner L, Zeug A, Kruse K, Lipp P.

Sci Rep. 2016 Nov 3;6:36028. doi: 10.1038/srep36028.


Inguinal Herniation Containing Bladder, Causing Contralateral Allograft Hydroureteronephrosis-A Case Report and Literature Review.

du Toit T, Kaestner L, Muller E, Kahn D.

Am J Transplant. 2017 Feb;17(2):565-568. doi: 10.1111/ajt.14052. Epub 2016 Oct 27. Review.


Novel Insights in the Regulation of Phosphatidylserine Exposure in Human Red Blood Cells.

Wesseling MC, Wagner-Britz L, Nguyen DB, Asanidze S, Mutua J, Mohamed N, Hanf B, Ghashghaeinia M, Kaestner L, Bernhardt I.

Cell Physiol Biochem. 2016;39(5):1941-1954. Epub 2016 Oct 24.


Hyperaldosteronism induces left atrial systolic and diastolic dysfunction.

Reil JC, Tauchnitz M, Tian Q, Hohl M, Linz D, Oberhofer M, Kaestner L, Reil GH, Thiele H, Steendijk P, Böhm M, Neuberger HR, Lipp P.

Am J Physiol Heart Circ Physiol. 2016 Oct 1;311(4):H1014-H1023. doi: 10.1152/ajpheart.00261.2016. Epub 2016 Sep 9.


Cardiac N-methyl D-aspartate Receptors as a Pharmacological Target.

Makhro A, Tian Q, Kaestner L, Kosenkov D, Faggian G, Gassmann M, Schwarzwald C, Bogdanova A.

J Cardiovasc Pharmacol. 2016 Nov;68(5):356-373.


Red Cell Properties after Different Modes of Blood Transportation.

Makhro A, Huisjes R, Verhagen LP, Mañú-Pereira Mdel M, Llaudet-Planas E, Petkova-Kirova P, Wang J, Eichler H, Bogdanova A, van Wijk R, Vives-Corrons JL, Kaestner L.

Front Physiol. 2016 Jul 15;7:288. doi: 10.3389/fphys.2016.00288. eCollection 2016.


Comparing the impact of an acute exercise bout on plasma amino acid composition, intraerythrocytic Ca(2+) handling, and red cell function in athletes and untrained subjects.

Makhro A, Haider T, Wang J, Bogdanov N, Steffen P, Wagner C, Meyer T, Gassmann M, Hecksteden A, Kaestner L, Bogdanova A.

Cell Calcium. 2016 Oct;60(4):235-44. doi: 10.1016/j.ceca.2016.05.005. Epub 2016 May 24.


Measurements of Intracellular Ca2+ Content and Phosphatidylserine Exposure in Human Red Blood Cells: Methodological Issues.

Wesseling MC, Wagner-Britz L, Boukhdoud F, Asanidze S, Nguyen DB, Kaestner L, Bernhardt I.

Cell Physiol Biochem. 2016;38(6):2414-25. doi: 10.1159/000445593. Epub 2016 Jun 13.


Novel potential serological prostate cancer biomarkers using CT100+ cancer antigen microarray platform in a multi-cultural South African cohort.

Adeola HA, Smith M, Kaestner L, Blackburn JM, Zerbini LF.

Oncotarget. 2016 Mar 22;7(12):13945-64. doi: 10.18632/oncotarget.7359.


Endothelin-1-induced remodelling of murine adult ventricular myocytes.

Viero C, Wegener S, Scholz A, Ruppenthal S, Tian Q, Tabellion W, Kreinest M, Laschke MW, Kaestner L, Lipp P.

Cell Calcium. 2016 Jan;59(1):41-53. doi: 10.1016/j.ceca.2015.12.005. Epub 2016 Jan 5.


In silico verification and parallel reaction monitoring prevalidation of potential prostate cancer biomarkers.

Adeola HA, Calder B, Soares NC, Kaestner L, Blackburn JM, Zerbini LF.

Future Oncol. 2016 Jan;12(1):43-57. doi: 10.2217/fon.15.296. Epub 2015 Nov 30.


Cardiac remodeling in Gαq and Gα11 knockout mice.

Wiesen K, Kaiser E, Schröder L, Scholz A, Ruppenthal S, Reil JC, Backes C, Meese E, Meier C, Bogdanova A, Lipp P, Kaestner L.

Int J Cardiol. 2016 Jan 1;202:836-45. doi: 10.1016/j.ijcard.2015.10.069. Epub 2015 Oct 9.


Genetically Encoded Voltage Indicators in Circulation Research.

Kaestner L, Tian Q, Kaiser E, Xian W, Müller A, Oberhofer M, Ruppenthal S, Sinnecker D, Tsutsui H, Miyawaki A, Moretti A, Lipp P.

Int J Mol Sci. 2015 Sep 8;16(9):21626-42. doi: 10.3390/ijms160921626. Review.


Channelizing the red blood cell: molecular biology competes with patch-clamp.

Kaestner L.

Front Mol Biosci. 2015 Aug 11;2:46. doi: 10.3389/fmolb.2015.00046. eCollection 2015. No abstract available.


A background Ca2+ entry pathway mediated by TRPC1/TRPC4 is critical for development of pathological cardiac remodelling.

Camacho Londoño JE, Tian Q, Hammer K, Schröder L, Camacho Londoño J, Reil JC, He T, Oberhofer M, Mannebach S, Mathar I, Philipp SE, Tabellion W, Schweda F, Dietrich A, Kaestner L, Laufs U, Birnbaumer L, Flockerzi V, Freichel M, Lipp P.

Eur Heart J. 2015 Sep 1;36(33):2257-66. doi: 10.1093/eurheartj/ehv250. Epub 2015 Jun 11.


Arrhythmia causes lipid accumulation and reduced glucose uptake.

Lenski M, Schleider G, Kohlhaas M, Adrian L, Adam O, Tian Q, Kaestner L, Lipp P, Lehrke M, Maack C, Böhm M, Laufs U.

Basic Res Cardiol. 2015;110(4):40. doi: 10.1007/s00395-015-0497-2. Epub 2015 May 28.


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