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Items: 34

1.

A phase I study of enfortumab vedotin in Japanese patients with locally advanced or metastatic urothelial carcinoma.

Takahashi S, Uemura M, Kimura T, Kawasaki Y, Takamoto A, Yamaguchi A, Melhem-Bertrandt A, Gartner EM, Inoue T, Akazawa R, Kadokura T, Tanikawa T.

Invest New Drugs. 2019 Aug 14. doi: 10.1007/s10637-019-00844-x. [Epub ahead of print]

PMID:
31444589
2.
3.

The maximum chemiluminescence intensity predicts severe neutropenia in gemcitabine-treated patients with pancreatic or biliary tract cancer.

Goto K, Matsuyama R, Suwa Y, Arisaka S, Kadokura T, Sato M, Mori R, Kumamoto T, Taguri M, Endo I.

Cancer Chemother Pharmacol. 2018 Dec;82(6):953-960. doi: 10.1007/s00280-018-3685-6. Epub 2018 Sep 14.

4.

Adenine Addition Restores Cell Viability and Butanol Production in Clostridium saccharoperbutylacetonicum N1-4 (ATCC 13564) Cultivated at 37°C.

Kiyoshi K, Kawashima S, Nobuki K, Kadokura T, Nakazato A, Suzuki KI, Nakayama S.

Appl Environ Microbiol. 2017 Mar 17;83(7). pii: e02960-16. doi: 10.1128/AEM.02960-16. Print 2017 Apr 1.

5.

IL-7 and procalcitonin are useful biomarkers in the comprehensive evaluation of the severity of acute cholangitis.

Suwa Y, Matsuyama R, Goto K, Kadokura T, Sato M, Mori R, Kumamoto T, Taguri M, Miyasho T, Endo I.

J Hepatobiliary Pancreat Sci. 2017 Feb;24(2):81-88. doi: 10.1002/jhbp.420.

PMID:
28002647
6.

Hinesol, a compound isolated from the essential oils of Atractylodes lancea rhizome, inhibits cell growth and induces apoptosis in human leukemia HL-60 cells.

Masuda Y, Kadokura T, Ishii M, Takada K, Kitajima J.

J Nat Med. 2015 Jul;69(3):332-9. doi: 10.1007/s11418-015-0897-5. Epub 2015 Apr 2.

PMID:
25833731
7.

Butanol production from alkali-pretreated rice straw by co-culture of Clostridium thermocellum and Clostridium saccharoperbutylacetonicum.

Kiyoshi K, Furukawa M, Seyama T, Kadokura T, Nakazato A, Nakayama S.

Bioresour Technol. 2015 Jun;186:325-328. doi: 10.1016/j.biortech.2015.03.061. Epub 2015 Mar 19.

PMID:
25818258
8.

Clinical pharmacokinetics and pharmacodynamics of the novel SGLT2 inhibitor ipragliflozin.

Kadokura T, Zhang W, Krauwinkel W, Leeflang S, Keirns J, Taniuchi Y, Nakajo I, Smulders R.

Clin Pharmacokinet. 2014 Nov;53(11):975-88. doi: 10.1007/s40262-014-0180-z. Review.

PMID:
25316572
9.

Pharmacokinetic and pharmacodynamic study of ipragliflozin in Japanese patients with type 2 diabetes mellitus: a randomized, double-blind, placebo-controlled study.

Kadokura T, Akiyama N, Kashiwagi A, Utsuno A, Kazuta K, Yoshida S, Nagase I, Smulders R, Kageyama S.

Diabetes Res Clin Pract. 2014 Oct;106(1):50-6. doi: 10.1016/j.diabres.2014.07.020. Epub 2014 Jul 26.

PMID:
25149596
10.

The pharmacokinetics of darexaban (YM150), an oral direct factor Xa inhibitor, are not affected by ketoconazole, a strong inhibitor of CYP3A and P-glycoprotein.

Groenendaal D, Strabach G, Garcia-Hernandez A, Kadokura T, Heeringa M, Mol R, Eltink C, Onkels H.

Clin Pharmacol Drug Dev. 2014 May;3(3):194-201. doi: 10.1002/cpdd.93. Epub 2014 Mar 3.

PMID:
27128609
11.

Clinical Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Darexaban, an Oral Direct Factor Xa Inhibitor, in Healthy Elderly Japanese Subjects.

Kadokura T, Oikawa K, Miyata K, Murase T, Nakamura M.

Clin Pharmacol Drug Dev. 2013 Oct;2(4):328-35. doi: 10.1002/cpdd.50. Epub 2013 Aug 16.

PMID:
27121937
12.

Clinical pharmacokinetics, pharmacodynamics, safety and tolerability of darexaban, an oral direct factor Xa inhibitor, in healthy Caucasian and Japanese subjects.

Kadokura T, Kashiwa M, Groenendaal D, Heeringa M, Mol R, Verheggen F, Garcia-Hernandez A, Onkels H.

Biopharm Drug Dispos. 2013 Nov;34(8):431-41. doi: 10.1002/bdd.1858. Epub 2013 Sep 20.

PMID:
23929659
13.

Ipragliflozin does not prolong QTc interval in healthy male and female subjects: a phase I study.

Zhang W, Smulders R, Abeyratne A, Dietz A, Krauwinkel W, Kadokura T, Keirns J.

Clin Ther. 2013 Aug;35(8):1150-1161.e3. doi: 10.1016/j.clinthera.2013.06.009. Epub 2013 Aug 2.

PMID:
23910665
14.

Isolation of a high malic and low acetic acid-producing sake yeast Saccharomyces cerevisiae strain screened from respiratory inhibitor 2,4-dinitrophenol (DNP)-resistant strains.

Kosugi S, Kiyoshi K, Oba T, Kusumoto K, Kadokura T, Nakazato A, Nakayama S.

J Biosci Bioeng. 2014 Jan;117(1):39-44. doi: 10.1016/j.jbiosc.2013.06.016. Epub 2013 Jul 16.

PMID:
23867095
15.

Severity and prognostic assessment of the endotoxin activity assay in biliary tract infection.

Sato M, Matsuyama R, Kadokura T, Mori R, Kumamoto T, Nojiri K, Taniguchi K, Takeda K, Kubota K, Tanaka K, Endo I.

J Hepatobiliary Pancreat Sci. 2014 Feb;21(2):120-7. doi: 10.1002/jhbp.10. Epub 2013 Jun 20.

PMID:
23798326
16.

Darexaban (YM150), an oral direct factor Xa inhibitor, has no effect on the pharmacokinetics of digoxin.

Kadokura T, Groenendaal D, Heeringa M, Mol R, Verheggen F, Garcia-Hernandez A, Onkels H.

Eur J Drug Metab Pharmacokinet. 2014 Mar;39(1):1-9. doi: 10.1007/s13318-013-0141-1. Epub 2013 Jun 11.

PMID:
23754514
17.

The effect of moderate hepatic impairment on the pharmacokinetics of ipragliflozin, a novel sodium glucose co-transporter 2 (SGLT2) inhibitor.

Zhang W, Krauwinkel WJ, Keirns J, Townsend RW, Lasseter KC, Plumb L, Kadokura T, Ushigome F, Smulders R.

Clin Drug Investig. 2013 Jul;33(7):489-96. doi: 10.1007/s40261-013-0089-6.

PMID:
23733389
18.

Order-disorder oscillations in exciton-polariton superfluids.

Saito H, Aioi T, Kadokura T.

Phys Rev Lett. 2013 Jan 11;110(2):026401. Epub 2013 Jan 7.

PMID:
23383923
19.

Renal glucose handling: impact of chronic kidney disease and sodium-glucose cotransporter 2 inhibition in patients with type 2 diabetes.

Ferrannini E, Veltkamp SA, Smulders RA, Kadokura T.

Diabetes Care. 2013 May;36(5):1260-5. doi: 10.2337/dc12-1503. Epub 2013 Jan 28.

20.

Effect of food on the pharmacokinetics of darexaban, an oral direct factor Xa inhibitor, in healthy Japanese subjects.

Kadokura T, Taniuchi Y, Inoue H, Saito M, Iwahana M, Yamada S, Urae A, Nakamura M.

Int J Clin Pharmacol Ther. 2013 Mar;51(3):200-6. doi: 10.5414/CP201804.

PMID:
23211396
21.

Decreased hydrogen production leads to selective butanol production in co-cultures of Clostridium thermocellum and Clostridium saccharoperbutylacetonicum strain N1-4.

Nakayama S, Bando Y, Ohnishi A, Kadokura T, Nakazato A.

J Biosci Bioeng. 2013 Feb;115(2):173-5. doi: 10.1016/j.jbiosc.2012.08.020. Epub 2012 Sep 19.

PMID:
22999358
22.

Combination treatment with ipragliflozin and metformin: a randomized, double-blind, placebo-controlled study in patients with type 2 diabetes mellitus.

Veltkamp SA, van Dijk J, Collins C, van Bruijnsvoort M, Kadokura T, Smulders RA.

Clin Ther. 2012 Aug;34(8):1761-71. doi: 10.1016/j.clinthera.2012.06.027. Epub 2012 Jul 15.

PMID:
22795925
23.

The pharmacokinetics of darexaban are not affected to a clinically relevant degree by rifampicin, a strong inducer of P-glycoprotein and CYP3A4.

Groenendaal D, Strabach G, Garcia-Hernandez A, Kadokura T, Heeringa M, Mol R, Eltink C, Onkels H.

Br J Clin Pharmacol. 2013 Feb;75(2):440-9. doi: 10.1111/j.1365-2125.2012.04346.x.

24.

No pharmacokinetic interaction between ipragliflozin and sitagliptin, pioglitazone, or glimepiride in healthy subjects.

Smulders RA, Zhang W, Veltkamp SA, van Dijk J, Krauwinkel WJ, Keirns J, Kadokura T.

Diabetes Obes Metab. 2012 Oct;14(10):937-43. doi: 10.1111/j.1463-1326.2012.01624.x. Epub 2012 Jun 7.

PMID:
22587345
25.

Characteristics of the high malic acid production mechanism in Saccharomyces cerevisiae sake yeast strain No. 28.

Nakayama S, Tabata K, Oba T, Kusumoto K, Mitsuiki S, Kadokura T, Nakazato A.

J Biosci Bioeng. 2012 Sep;114(3):281-5. doi: 10.1016/j.jbiosc.2012.04.003. Epub 2012 May 8.

PMID:
22575438
26.

Discovery of N-[2-hydroxy-6-(4-methoxybenzamido)phenyl]-4- (4-methyl-1,4-diazepan-1-yl)benzamide (darexaban, YM150) as a potent and orally available factor Xa inhibitor.

Hirayama F, Koshio H, Ishihara T, Hachiya S, Sugasawa K, Koga Y, Seki N, Shiraki R, Shigenaga T, Iwatsuki Y, Moritani Y, Mori K, Kadokura T, Kawasaki T, Matsumoto Y, Sakamoto S, Tsukamoto S.

J Med Chem. 2011 Dec 8;54(23):8051-65. doi: 10.1021/jm200868m. Epub 2011 Nov 11.

PMID:
21995444
27.

Effect of Ipragliflozin (ASP1941), a novel selective sodium-dependent glucose co-transporter 2 inhibitor, on urinary glucose excretion in healthy subjects.

Veltkamp SA, Kadokura T, Krauwinkel WJ, Smulders RA.

Clin Drug Investig. 2011 Dec 1;31(12):839-51. doi: 10.2165/11594330-000000000-00000.

PMID:
21877761
28.

Butanol production from crystalline cellulose by cocultured Clostridium thermocellum and Clostridium saccharoperbutylacetonicum N1-4.

Nakayama S, Kiyoshi K, Kadokura T, Nakazato A.

Appl Environ Microbiol. 2011 Sep;77(18):6470-5. doi: 10.1128/AEM.00706-11. Epub 2011 Jul 15.

29.

The effect of fluvoxamine on the pharmacokinetics, safety, and tolerability of ramosetron in healthy subjects.

Kadokura T, den Adel M, Krauwinkel WJ, Takeshige T, Nishida A.

Eur J Clin Pharmacol. 2008 Jul;64(7):691-5. doi: 10.1007/s00228-008-0466-x. Epub 2008 Apr 26.

PMID:
18438654
30.

The effect of paroxetine on the pharmacokinetics, safety, and tolerability of ramosetron in healthy subjects.

Kadokura T, den Adel M, Krauwinkel WJ, Takeshige T, Nishida A.

Eur J Clin Pharmacol. 2008 Jun;64(6):605-9. doi: 10.1007/s00228-008-0472-z.

PMID:
18401578
31.

Divergence of glyceraldehyde-3-phosphate dehydrogenase isozymes in Saccharomyces cerevisiae complex.

Kadokura T, Ito T, Takano S, Nakazato A, Hara H, Watanabe S, Kudo T, Takeda M, Kaneko T.

Syst Appl Microbiol. 2000 Jun;23(2):198-205.

PMID:
10930071
32.

1,5-Anhydroglucitol promotes glycogenolysis in Escherichia coli.

Shiga Y, Kametani S, Kadokura T, Akanuma H.

J Biochem. 1999 Jan;125(1):166-72.

33.

Comparison of the structural characteristics of chromosome VI in Saccharomyces sensu stricto: the divergence, species-dependent features and uniqueness of saké yeasts.

Nakazato A, Kadokura T, Amano M, Harayama T, Murakami Y, Takeda M, Ohkuma M, Kudo T, Kaneko T.

Yeast. 1998 Jun 15;14(8):723-31.

34.

[Basilar insufficiency; with special reference to the vertebroangiography and cerebral hemodynamics in young and aged patients].

Kadokura T.

Nihon Ika Daigaku Zasshi. 1970 Apr;37(2):100-7. Japanese. No abstract available.

PMID:
5457087

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