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Items: 1 to 50 of 141

1.

Importance of the circadian clock in tendon development.

Yeung CC, Kadler KE.

Curr Top Dev Biol. 2019;133:309-342. doi: 10.1016/bs.ctdb.2018.11.004. Epub 2018 Dec 20.

PMID:
30902257
2.

Preservation of circadian rhythms by the protein folding chaperone, BiP.

Pickard A, Chang J, Alachkar N, Calverley B, Garva R, Arvan P, Meng QJ, Kadler KE.

FASEB J. 2019 Jun;33(6):7479-7489. doi: 10.1096/fj.201802366RR. Epub 2019 Mar 19.

3.

4-Sodium phenyl butyric acid has both efficacy and counter-indicative effects in the treatment of Col4a1 disease.

Jones FE, Murray LS, McNeilly S, Dean A, Aman A, Lu Y, Nikolova N, Malomgré R, Horsburgh K, Holmes WM, Kadler KE, Van Agtmael T.

Hum Mol Genet. 2019 Feb 15;28(4):628-638. doi: 10.1093/hmg/ddy369.

4.

Synchronized mechanical oscillations at the cell-matrix interface in the formation of tensile tissue.

Holmes DF, Yeung CC, Garva R, Zindy E, Taylor SH, Lu Y, Watson S, Kalson NS, Kadler KE.

Proc Natl Acad Sci U S A. 2018 Oct 2;115(40):E9288-E9297. doi: 10.1073/pnas.1801759115. Epub 2018 Sep 20.

5.

Cellular homeostatic tension and force transmission measured in human engineered tendon.

Giannopoulos A, Svensson RB, Heinemeier KM, Schjerling P, Kadler KE, Holmes DF, Kjaer M, Magnusson SP.

J Biomech. 2018 Sep 10;78:161-165. doi: 10.1016/j.jbiomech.2018.07.032. Epub 2018 Jul 30.

6.

Age-related dataset on the mechanical properties and collagen fibril structure of tendons from a murine model.

Goh KL, Holmes DF, Lu YH, Kadler KE, Purslow PP.

Sci Data. 2018 Jul 24;5:180140. doi: 10.1038/sdata.2018.140.

7.

Changes in S100 Proteins Identified in Healthy Skin following Electrical Stimulation: Relevance for Wound Healing.

Lallyett C, Yeung CC, Nielson RH, Zeef LAH, Chapman-Jones D, Kjaer M, Kadler KE.

Adv Skin Wound Care. 2018 Jul;31(7):322-327. doi: 10.1097/01.ASW.0000533722.06780.03.

PMID:
29923902
8.

Live imaging of collagen deposition during skin development and repair in a collagen I - GFP fusion transgenic zebrafish line.

Morris JL, Cross SJ, Lu Y, Kadler KE, Lu Y, Dallas SL, Martin P.

Dev Biol. 2018 Sep 1;441(1):4-11. doi: 10.1016/j.ydbio.2018.06.001. Epub 2018 Jun 6.

9.

Collagen Fibril Assembly and Function.

Holmes DF, Lu Y, Starborg T, Kadler KE.

Curr Top Dev Biol. 2018;130:107-142. doi: 10.1016/bs.ctdb.2018.02.004. Epub 2018 Mar 21. Review.

PMID:
29853175
10.

Non-muscle myosin IIB (Myh10) is required for epicardial function and coronary vessel formation during mammalian development.

Ridge LA, Mitchell K, Al-Anbaki A, Shaikh Qureshi WM, Stephen LA, Tenin G, Lu Y, Lupu IE, Clowes C, Robertson A, Barnes E, Wright JA, Keavney B, Ehler E, Lovell SC, Kadler KE, Hentges KE.

PLoS Genet. 2017 Oct 30;13(10):e1007068. doi: 10.1371/journal.pgen.1007068. eCollection 2017 Oct.

11.

Targeting lysyl oxidase reduces peritoneal fibrosis.

Harlow CR, Wu X, van Deemter M, Gardiner F, Poland C, Green R, Sarvi S, Brown P, Kadler KE, Lu Y, Mason JI, Critchley HOD, Hillier SG.

PLoS One. 2017 Aug 11;12(8):e0183013. doi: 10.1371/journal.pone.0183013. eCollection 2017.

12.

Fell Muir Lecture: Collagen fibril formation in vitro and in vivo.

Kadler KE.

Int J Exp Pathol. 2017 Feb;98(1):4-16. doi: 10.1111/iep.12224. Epub 2017 May 16. Review.

13.

Evidence of structurally continuous collagen fibrils in tendons.

Svensson RB, Herchenhan A, Starborg T, Larsen M, Kadler KE, Qvortrup K, Magnusson SP.

Acta Biomater. 2017 Mar 1;50:293-301. doi: 10.1016/j.actbio.2017.01.006. Epub 2017 Jan 5.

14.

Deposition of collagen type I onto skeletal endothelium reveals a new role for blood vessels in regulating bone morphology.

Ben Shoham A, Rot C, Stern T, Krief S, Akiva A, Dadosh T, Sabany H, Lu Y, Kadler KE, Zelzer E.

Development. 2016 Nov 1;143(21):3933-3943. Epub 2016 Sep 12.

15.

Three-dimensional electron microscopy reveals the evolution of glomerular barrier injury.

Randles MJ, Collinson S, Starborg T, Mironov A, Krendel M, Königshausen E, Sellin L, Roberts IS, Kadler KE, Miner JH, Lennon R.

Sci Rep. 2016 Oct 11;6:35068. doi: 10.1038/srep35068.

16.

Key Matrix Proteins Within the Pancreatic Islet Basement Membrane Are Differentially Digested During Human Islet Isolation.

Cross SE, Vaughan RH, Willcox AJ, McBride AJ, Abraham AA, Han B, Johnson JD, Maillard E, Bateman PA, Ramracheya RD, Rorsman P, Kadler KE, Dunne MJ, Hughes SJ, Johnson PR.

Am J Transplant. 2017 Feb;17(2):451-461. doi: 10.1111/ajt.13975. Epub 2016 Sep 6.

17.

Enhanced Islet Cell Nucleomegaly Defines Diffuse Congenital Hyperinsulinism in Infancy but Not Other Forms of the Disease.

Han B, Newbould M, Batra G, Cheesman E, Craigie RJ, Mohamed Z, Rigby L, Padidela R, Skae M, Mironov A, Starborg T, Kadler KE, Cosgrove KE, Banerjee I, Dunne MJ.

Am J Clin Pathol. 2016 Jun;145(6):757-68. doi: 10.1093/ajcp/aqw075.

18.

Fibroblast-Derived MMP-14 Regulates Collagen Homeostasis in Adult Skin.

Zigrino P, Brinckmann J, Niehoff A, Lu Y, Giebeler N, Eckes B, Kadler KE, Mauch C.

J Invest Dermatol. 2016 Aug;136(8):1575-1583. doi: 10.1016/j.jid.2016.03.036. Epub 2016 Apr 9.

19.

ER stress and basement membrane defects combine to cause glomerular and tubular renal disease resulting from Col4a1 mutations in mice.

Jones FE, Bailey MA, Murray LS, Lu Y, McNeilly S, Schlötzer-Schrehardt U, Lennon R, Sado Y, Brownstein DG, Mullins JJ, Kadler KE, Van Agtmael T.

Dis Model Mech. 2016 Feb;9(2):165-76. doi: 10.1242/dmm.021741.

20.

Matrix metalloproteinase 14 is required for fibrous tissue expansion.

Taylor SH, Yeung CY, Kalson NS, Lu Y, Zigrino P, Starborg T, Warwood S, Holmes DF, Canty-Laird EG, Mauch C, Kadler KE.

Elife. 2015 Sep 21;4:e09345. doi: 10.7554/eLife.09345.

21.

Chick tendon fibroblast transcriptome and shape depend on whether the cell has made its own collagen matrix.

Yeung CY, Zeef LA, Lallyett C, Lu Y, Canty-Laird EG, Kadler KE.

Sci Rep. 2015 Sep 4;5:13555. doi: 10.1038/srep13555.

22.

A structure-based extracellular matrix expansion mechanism of fibrous tissue growth.

Kalson NS, Lu Y, Taylor SH, Starborg T, Holmes DF, Kadler KE.

Elife. 2015 May 20;4. doi: 10.7554/eLife.05958.

23.

Lysyl Oxidase Activity Is Required for Ordered Collagen Fibrillogenesis by Tendon Cells.

Herchenhan A, Uhlenbrock F, Eliasson P, Weis M, Eyre D, Kadler KE, Magnusson SP, Kjaer M.

J Biol Chem. 2015 Jun 26;290(26):16440-50. doi: 10.1074/jbc.M115.641670. Epub 2015 May 15.

24.

Serial block face-scanning electron microscopy: a tool for studying embryonic development at the cell-matrix interface.

Starborg T, Kadler KE.

Birth Defects Res C Embryo Today. 2015 Mar;105(1):9-18. doi: 10.1002/bdrc.21087. Review.

PMID:
25820245
25.

Ablating hedgehog signaling in tenocytes during development impairs biomechanics and matrix organization of the adult murine patellar tendon enthesis.

Breidenbach AP, Aschbacher-Smith L, Lu Y, Dyment NA, Liu CF, Liu H, Wylie C, Rao M, Shearn JT, Rowe DW, Kadler KE, Jiang R, Butler DL.

J Orthop Res. 2015 Aug;33(8):1142-51. doi: 10.1002/jor.22899. Epub 2015 Apr 14.

26.

Tendon functional extracellular matrix.

Screen HR, Berk DE, Kadler KE, Ramirez F, Young MF.

J Orthop Res. 2015 Jun;33(6):793-9. doi: 10.1002/jor.22818. Review.

27.

The needle in the ECM haystack.

Kadler KE.

Nat Rev Mol Cell Biol. 2014 Dec;15(12):769. doi: 10.1038/nrm3899. Epub 2014 Oct 22. No abstract available.

PMID:
25355504
28.

Fibrin gels exhibit improved biological, structural, and mechanical properties compared with collagen gels in cell-based tendon tissue-engineered constructs.

Breidenbach AP, Dyment NA, Lu Y, Rao M, Shearn JT, Rowe DW, Kadler KE, Butler DL.

Tissue Eng Part A. 2015 Feb;21(3-4):438-50. doi: 10.1089/ten.TEA.2013.0768. Epub 2014 Nov 13.

29.

Arhgap28 is a RhoGAP that inactivates RhoA and downregulates stress fibers.

Yeung CY, Taylor SH, Garva R, Holmes DF, Zeef LA, Soininen R, Boot-Handford RP, Kadler KE.

PLoS One. 2014 Sep 11;9(9):e107036. doi: 10.1371/journal.pone.0107036. eCollection 2014.

30.

Gremlin-2 is a BMP antagonist that is regulated by the circadian clock.

Yeung CY, Gossan N, Lu Y, Hughes A, Hensman JJ, Bayer ML, Kjær M, Kadler KE, Meng QJ.

Sci Rep. 2014 Jun 5;4:5183. doi: 10.1038/srep05183.

31.

3-D ultrastructure and collagen composition of healthy and overloaded human tendon: evidence of tenocyte and matrix buckling.

Pingel J, Lu Y, Starborg T, Fredberg U, Langberg H, Nedergaard A, Weis M, Eyre D, Kjaer M, Kadler KE.

J Anat. 2014 May;224(5):548-55. doi: 10.1111/joa.12164. Epub 2014 Feb 9.

32.

Three-dimensional aspects of matrix assembly by cells in the developing cornea.

Young RD, Knupp C, Pinali C, Png KM, Ralphs JR, Bushby AJ, Starborg T, Kadler KE, Quantock AJ.

Proc Natl Acad Sci U S A. 2014 Jan 14;111(2):687-92. doi: 10.1073/pnas.1313561110. Epub 2014 Jan 2.

33.

Nonmuscle myosin II powered transport of newly formed collagen fibrils at the plasma membrane.

Kalson NS, Starborg T, Lu Y, Mironov A, Humphries SM, Holmes DF, Kadler KE.

Proc Natl Acad Sci U S A. 2013 Dec 3;110(49):E4743-52. doi: 10.1073/pnas.1314348110. Epub 2013 Nov 18.

34.

Chemical chaperone treatment reduces intracellular accumulation of mutant collagen IV and ameliorates the cellular phenotype of a COL4A2 mutation that causes haemorrhagic stroke.

Murray LS, Lu Y, Taggart A, Van Regemorter N, Vilain C, Abramowicz M, Kadler KE, Van Agtmael T.

Hum Mol Genet. 2014 Jan 15;23(2):283-92. doi: 10.1093/hmg/ddt418. Epub 2013 Sep 2.

35.

Transcription factor EGR1 directs tendon differentiation and promotes tendon repair.

Guerquin MJ, Charvet B, Nourissat G, Havis E, Ronsin O, Bonnin MA, Ruggiu M, Olivera-Martinez I, Robert N, Lu Y, Kadler KE, Baumberger T, Doursounian L, Berenbaum F, Duprez D.

J Clin Invest. 2013 Aug;123(8):3564-76. doi: 10.1172/JCI67521. Epub 2013 Jul 25.

36.

Using transmission electron microscopy and 3View to determine collagen fibril size and three-dimensional organization.

Starborg T, Kalson NS, Lu Y, Mironov A, Cootes TF, Holmes DF, Kadler KE.

Nat Protoc. 2013;8(7):1433-48. doi: 10.1038/nprot.2013.086. Epub 2013 Jun 27.

37.

Bimodal collagen fibril diameter distributions direct age-related variations in tendon resilience and resistance to rupture.

Goh KL, Holmes DF, Lu Y, Purslow PP, Kadler KE, Bechet D, Wess TJ.

J Appl Physiol (1985). 2012 Sep;113(6):878-88. doi: 10.1152/japplphysiol.00258.2012. Epub 2012 Jul 26.

38.

Collagen XXVII organises the pericellular matrix in the growth plate.

Plumb DA, Ferrara L, Torbica T, Knowles L, Mironov A Jr, Kadler KE, Briggs MD, Boot-Handford RP.

PLoS One. 2011;6(12):e29422. doi: 10.1371/journal.pone.0029422. Epub 2011 Dec 19.

39.

Slow stretching that mimics embryonic growth rate stimulates structural and mechanical development of tendon-like tissue in vitro.

Kalson NS, Holmes DF, Herchenhan A, Lu Y, Starborg T, Kadler KE.

Dev Dyn. 2011 Nov;240(11):2520-8. doi: 10.1002/dvdy.22760.

40.

Stepwise proteolytic activation of type I procollagen to collagen within the secretory pathway of tendon fibroblasts in situ.

Canty-Laird EG, Lu Y, Kadler KE.

Biochem J. 2012 Jan 15;441(2):707-17. doi: 10.1042/BJ20111379.

41.

Tenocyte contraction induces crimp formation in tendon-like tissue.

Herchenhan A, Kalson NS, Holmes DF, Hill P, Kadler KE, Margetts L.

Biomech Model Mechanobiol. 2012 Mar;11(3-4):449-59. doi: 10.1007/s10237-011-0324-0. Epub 2011 Jul 7.

42.

Tendon is covered by a basement membrane epithelium that is required for cell retention and the prevention of adhesion formation.

Taylor SH, Al-Youha S, Van Agtmael T, Lu Y, Wong J, McGrouther DA, Kadler KE.

PLoS One. 2011 Jan 26;6(1):e16337. doi: 10.1371/journal.pone.0016337.

43.

Synthesis of embryonic tendon-like tissue by human marrow stromal/mesenchymal stem cells requires a three-dimensional environment and transforming growth factor β3.

Kapacee Z, Yeung CY, Lu Y, Crabtree D, Holmes DF, Kadler KE.

Matrix Biol. 2010 Oct;29(8):668-77. doi: 10.1016/j.matbio.2010.08.005. Epub 2010 Aug 22.

44.

An experimental model for studying the biomechanics of embryonic tendon: Evidence that the development of mechanical properties depends on the actinomyosin machinery.

Kalson NS, Holmes DF, Kapacee Z, Otermin I, Lu Y, Ennos RA, Canty-Laird EG, Kadler KE.

Matrix Biol. 2010 Oct;29(8):678-89. doi: 10.1016/j.matbio.2010.08.009. Epub 2010 Aug 22.

45.

The cell biology of suturing tendons.

Wong JK, Alyouha S, Kadler KE, Ferguson MW, McGrouther DA.

Matrix Biol. 2010 Jul;29(6):525-36. doi: 10.1016/j.matbio.2010.06.002. Epub 2010 Jun 21.

46.

Growth of collagen fibril seeds from embryonic tendon: fractured fibril ends nucleate new tip growth.

Holmes DF, Tait A, Hodson NW, Sherratt MJ, Kadler KE.

J Mol Biol. 2010 May 28;399(1):9-16. doi: 10.1016/j.jmb.2010.04.008. Epub 2010 Apr 10.

47.

The angiogenic inhibitor long pentraxin PTX3 forms an asymmetric octamer with two binding sites for FGF2.

Inforzato A, Baldock C, Jowitt TA, Holmes DF, Lindstedt R, Marcellini M, Rivieccio V, Briggs DC, Kadler KE, Verdoliva A, Bottazzi B, Mantovani A, Salvatori G, Day AJ.

J Biol Chem. 2010 Jun 4;285(23):17681-92. doi: 10.1074/jbc.M109.085639. Epub 2010 Apr 2.

48.

First evidence of bone morphogenetic protein 1 expression and activity in sheep ovarian follicles.

Canty-Laird E, Carré GA, Mandon-Pépin B, Kadler KE, Fabre S.

Biol Reprod. 2010 Jul;83(1):138-46. doi: 10.1095/biolreprod.109.082115. Epub 2010 Mar 31.

49.

The initiation of embryonic-like collagen fibrillogenesis by adult human tendon fibroblasts when cultured under tension.

Bayer ML, Yeung CY, Kadler KE, Qvortrup K, Baar K, Svensson RB, Magnusson SP, Krogsgaard M, Koch M, Kjaer M.

Biomaterials. 2010 Jun;31(18):4889-97. doi: 10.1016/j.biomaterials.2010.02.062. Epub 2010 Mar 30.

50.

Structural and functional evidence for a substrate exclusion mechanism in mammalian tolloid like-1 (TLL-1) proteinase.

Berry R, Jowitt TA, Garrigue-Antar L, Kadler KE, Baldock C.

FEBS Lett. 2010 Feb 19;584(4):657-61. doi: 10.1016/j.febslet.2009.12.050. Epub 2009 Dec 30.

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