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Improvement in Patient-Reported Outcomes With Intensity-Modulated Radiotherapy (RT) Compared With Standard RT: A Report From the NRG Oncology RTOG 1203 Study.

Yeung AR, Pugh SL, Klopp AH, Gil KM, Wenzel L, Westin SN, Gaffney DK, Small W Jr, Thompson S, Doncals DE, Cantuaria GHC, Yaremko BP, Chang A, Kundapur V, Mohan DS, Haas ML, Kim YB, Ferguson CL, Deshmukh S, Bruner DW, Kachnic LA.

J Clin Oncol. 2020 Feb 19:JCO1902381. doi: 10.1200/JCO.19.02381. [Epub ahead of print]


Hippocampal Avoidance During Whole-Brain Radiotherapy Plus Memantine for Patients With Brain Metastases: Phase III Trial NRG Oncology CC001.

Brown PD, Gondi V, Pugh S, Tome WA, Wefel JS, Armstrong TS, Bovi JA, Robinson C, Konski A, Khuntia D, Grosshans D, Benzinger TLS, Bruner D, Gilbert MR, Roberge D, Kundapur V, Devisetty K, Shah S, Usuki K, Anderson BM, Stea B, Yoon H, Li J, Laack NN, Kruser TJ, Chmura SJ, Shi W, Deshmukh S, Mehta MP, Kachnic LA; for NRG Oncology.

J Clin Oncol. 2020 Feb 14:JCO1902767. doi: 10.1200/JCO.19.02767. [Epub ahead of print]


Disease Sites.

Chandra RA, Kachnic LA, Thomas CR Jr.

Hematol Oncol Clin North Am. 2020 Feb;34(1):xv-xvi. doi: 10.1016/j.hoc.2019.09.011. Epub 2019 Oct 28. No abstract available.


Pretreatment Volume of MRI-Determined White Matter Injury Predicts Neurocognitive Decline After Hippocampal Avoidant Whole-Brain Radiation Therapy for Brain Metastases: Secondary Analysis of NRG Oncology Radiation Therapy Oncology Group 0933.

Bovi JA, Pugh SL, Sabsevitz D, Robinson CG, Paulson E, Mehta MP, Gondi V, Kundapur V, Shahin MS, Chao ST, Machtay M, DeNittis AS, Laack NN, Greenspoon JN, Moore KN, Huang J, Dominello MM, Kachnic LA.

Adv Radiat Oncol. 2019 Jul 16;4(4):579-586. doi: 10.1016/j.adro.2019.07.006. eCollection 2019 Oct-Dec.


Current Issues and Techniques.

Chandra RA, Kachnic LA, Thomas CR Jr.

Hematol Oncol Clin North Am. 2019 Dec;33(6):xiii-xiv. doi: 10.1016/j.hoc.2019.09.001. Epub 2019 Oct 1. No abstract available.


Immortal Time Bias in National Cancer Database Studies.

Newman NB, Brett CL, Kluwe CA, Patel CG, Attia A, Osmundson EC, Kachnic LA.

Int J Radiat Oncol Biol Phys. 2020 Jan 1;106(1):5-12. doi: 10.1016/j.ijrobp.2019.07.056. Epub 2019 Aug 9.


Expanded validation of the EPIC bowel and urinary domains for use in women with gynecologic cancer undergoing postoperative radiotherapy.

Gil KM, Pugh SL, Klopp AH, Yeung AR, Wenzel L, Westin SN, Gaffney DK, Small W Jr, Thompson S, Doncals DE, Cantuaria GHC, Yaremko BP, Chang A, Kundapur V, Mohan DS, Haas ML, Kim YB, Ferguson CL, Deshmukh S, Kachnic LA, Bruner DW.

Gynecol Oncol. 2019 Jul;154(1):183-188. doi: 10.1016/j.ygyno.2019.04.682. Epub 2019 May 16.


The American Board of Radiology Initial Certification in Radiation Oncology: Moving Forward Through Collaboration.

Wallner PE, Kachnic LA, Alektiar KM, Davis BJ, Hardenbergh PH, Ng AK.

Int J Radiat Oncol Biol Phys. 2019 May 1;104(1):21-23. doi: 10.1016/j.ijrobp.2019.01.090. No abstract available.


An in-silico quality assurance study of contouring target volumes in thoracic tumors within a cooperative group setting.

Elhalawani H, Elgohari B, Lin TA, Mohamed ASR, Fitzgerald TJ, Laurie F, Ulin K, Kalpathy-Cramer J, Guerrero T, Holliday EB, Russo G, Patel A, Jones W, Walker GV, Awan M, Choi M, Dagan R, Mahmoud O, Shapiro A, Kong FS, Gomez D, Zeng J, Decker R, Spoelstra FOB, Gaspar LE, Kachnic LA, Thomas CR Jr, Okunieff P, Fuller CD.

Clin Transl Radiat Oncol. 2019 Jan 6;15:83-92. doi: 10.1016/j.ctro.2019.01.001. eCollection 2019 Feb.


Snapshot of a Specialty: Results of the ABR 2016 Radiation Oncology Clinical Practice Analysis.

Wallner PE, McGeagh AM, Gerdeman AM, Wilson LD, Shrieve DC, Alektiar KM, Hahn SM, Kachnic LA, Jackson VP.

J Am Coll Radiol. 2019 Apr;16(4 Pt A):513-517. doi: 10.1016/j.jacr.2018.11.002. Epub 2018 Dec 22.


Intensity-modulated radiotherapy improves survival and reduces treatment time in squamous cell carcinoma of the anus: A National Cancer Data Base study.

Elson JK, Kachnic LA, Kharofa JR.

Cancer. 2018 Nov 15;124(22):4383-4392. doi: 10.1002/cncr.31721. Epub 2018 Oct 17.


Randomized phase III trial to evaluate radiopharmaceuticals and zoledronic acid in the palliation of osteoblastic metastases from lung, breast, and prostate cancer: report of the NRG Oncology RTOG 0517 trial.

Seider MJ, Pugh SL, Langer C, Wyatt G, Demas W, Rashtian A, Clausen CL, Derdel JD, Cleary SF, Peters CA, Ramalingam A, Clarkson JE, Tomblyn M, Rabinovitch RA, Kachnic LA, Berk LB; NRG Oncology.

Ann Nucl Med. 2018 Oct;32(8):553-560. doi: 10.1007/s12149-018-1278-4. Epub 2018 Aug 9.


Neoadjuvant radiation for clinical T4 colon cancer: A potential improvement to overall survival.

Hawkins AT, Ford MM, Geiger TM, Hopkins MB, Kachnic LA, Muldoon RL, Glasgow SC.

Surgery. 2019 Feb;165(2):469-475. doi: 10.1016/j.surg.2018.06.015. Epub 2018 Jul 14.


Evolving Treatment Paradigm in the Treatment of Locally Advanced Rectal Cancer.

Smith CA, Kachnic LA.

J Natl Compr Canc Netw. 2018 Jul;16(7):909-915. doi: 10.6004/jnccn.2018.7032. Review.


Patient-Reported Toxicity During Pelvic Intensity-Modulated Radiation Therapy: NRG Oncology-RTOG 1203.

Klopp AH, Yeung AR, Deshmukh S, Gil KM, Wenzel L, Westin SN, Gifford K, Gaffney DK, Small W Jr, Thompson S, Doncals DE, Cantuaria GHC, Yaremko BP, Chang A, Kundapur V, Mohan DS, Haas ML, Kim YB, Ferguson CL, Pugh SL, Kachnic LA, Bruner DW.

J Clin Oncol. 2018 Aug 20;36(24):2538-2544. doi: 10.1200/JCO.2017.77.4273. Epub 2018 Jul 10. Erratum in: J Clin Oncol. 2019 Mar 20;37(9):761.


Patient Reported Outcomes in NRG Oncology RTOG 0938, Evaluating Two Ultrahypofractionated Regimens for Prostate Cancer.

Lukka HR, Pugh SL, Bruner DW, Bahary JP, Lawton CAF, Efstathiou JA, Kudchadker RJ, Ponsky LE, Seaward SA, Dayes IS, Gopaul DD, Michalski JM, Delouya G, Kaplan ID, Horwitz EM, Roach M 3rd, Pinover WH, Beyer DC, Amanie JO, Sandler HM, Kachnic LA.

Int J Radiat Oncol Biol Phys. 2018 Oct 1;102(2):287-295. doi: 10.1016/j.ijrobp.2018.06.008. Epub 2018 Jun 18.


Commentary on: Thoughts on the American Board of Radiology Examinations and the Resident Experience in Radiation Oncology.

Wallner PE, Kachnic LA, Gerdeman AM.

Pract Radiat Oncol. 2018 Sep - Oct;8(5):302-303. doi: 10.1016/j.prro.2018.04.005. Epub 2018 Apr 10. No abstract available.


Report from the SWOG Radiation Oncology Committee: Research Objectives Workshop 2017.

Okunieff P, Casey-Sawicki K, Lockney NA, Hoppe BS, Enderling H, Pinnix C, Welsh J, Krishnan S, Yothers G, Brown M, Knox S, Bristow R, Spellman P, Mitin T, Nabavizadeh N, Jaboin J, Manning HC, Feng F, Galbraith S, Solanki AA, Harkenrider MM, Tuli R, Decker RH, Finkelstein SE, Hsu CC, Ha CS, Jagsi R, Shumway D, Daly M, Wang TJC, Fitzgerald TJ, Laurie F, Marshall DT, Raben D, Constine L, Thomas CR Jr, Kachnic LA.

Clin Cancer Res. 2018 Aug 1;24(15):3500-3509. doi: 10.1158/1078-0432.CCR-17-3202. Epub 2018 Apr 16.


Randomized Clinical Trials in Localized Anal Cancer.

Smith CA, Kachnic LA.

Surg Oncol Clin N Am. 2017 Oct;26(4):705-718. doi: 10.1016/j.soc.2017.05.009. Epub 2017 Aug 18. Review.


Evolving Role of Radiotherapy in the Management of Rectal Carcinoma.

Smith CA, Kachnic LA.

Surg Oncol Clin N Am. 2017 Jul;26(3):455-466. doi: 10.1016/j.soc.2017.01.011. Review.


Perceptions and practices regarding women's vaginal health following radiation therapy: A survey of radiation oncologists practicing in the United States.

Kachnic LA, Bruner DW, Qureshi MM, Russo GA.

Pract Radiat Oncol. 2017 Sep - Oct;7(5):356-363. doi: 10.1016/j.prro.2017.02.003. Epub 2017 Feb 14.


Neoadjuvant Treatment for Locally Advanced Rectal Cancer: New Concepts in Clinical Trial Design.

Rana N, Chakravarthy AB, Kachnic LA.

Curr Treat Options Oncol. 2017 Feb;18(2):13. doi: 10.1007/s11864-017-0454-4. Review.


Building a palliative radiation oncology program: From bedside to B.E.D.

Stavas MJ, Pagan JD, Varma S, Li B, Kachnic LA.

Pract Radiat Oncol. 2017 May - Jun;7(3):203-208. doi: 10.1016/j.prro.2016.09.006. Epub 2016 Sep 13.


Significance of Co-expression of Epidermal Growth Factor Receptor and Ki67 on Clinical Outcome in Patients With Anal Cancer Treated With Chemoradiotherapy: An Analysis of NRG Oncology RTOG 9811.

Doll CM, Moughan J, Klimowicz A, Ho CK, Kornaga EN, Lees-Miller SP, Ajani JA, Crane CH, Kachnic LA, Okawara GS, Berk LB, Roof KS, Becker MJ, Grisell DL, Ellis RJ, Sperduto PW, Marsa GW, Guha C, Magliocco AM.

Int J Radiat Oncol Biol Phys. 2017 Mar 1;97(3):554-562. doi: 10.1016/j.ijrobp.2016.11.021. Epub 2016 Nov 23.


Evolution and Management of Treatment-Related Toxicity in Anal Cancer.

Ludmir EB, Kachnic LA, Czito BG.

Surg Oncol Clin N Am. 2017 Jan;26(1):91-113. doi: 10.1016/j.soc.2016.07.004. Review.


American Board of Radiology Maintenance of Certification Program: Evolution to Better Serve Stakeholders.

Wallner PE, Shrieve DC, Kachnic LA, Wilson LD, Hahn S, Alektiar KM, Laszakovits D, Guiberteau MJ.

Int J Radiat Oncol Biol Phys. 2016 Jan 1;94(1):16-18. doi: 10.1016/j.ijrobp.2015.09.003. No abstract available.


Raising the Next Generation of Physician-Scientists: The Chairs' Perspective. In Regard to Formenti et al.

Wallner PE, Shrieve DC, Kachnic LA, Wilson LD.

Int J Radiat Oncol Biol Phys. 2015 Nov 1;93(3):727-8. doi: 10.1016/j.ijrobp.2015.06.032. No abstract available.


Beliefs About Anal Cancer among HIV-Infected Women: Barriers and Motivators to Participation in Research.

Battaglia TA, Gunn CM, McCoy ME, Mu HH, Baranoski AS, Chiao EY, Kachnic LA, Stier EA.

Womens Health Issues. 2015 Nov-Dec;25(6):720-6. doi: 10.1016/j.whi.2015.06.008. Epub 2015 Aug 4.


Optimizing efficiency and safety in a radiation oncology department through the use of ARIA 11 Visual Care Path.

Kovalchuk N, Russo GA, Shin JY, Kachnic LA.

Pract Radiat Oncol. 2015 Sep-Oct;5(5):295-303. doi: 10.1016/j.prro.2015.05.001. Epub 2015 Jun 27. Erratum in: Pract Radiat Oncol. 2016 Mar-Apr:6(2):e47.


Efficacy endpoints of radiation therapy group protocol 0247: a randomized, phase 2 study of neoadjuvant radiation therapy plus concurrent capecitabine and irinotecan or capecitabine and oxaliplatin for patients with locally advanced rectal cancer.

Wong SJ, Moughan J, Meropol NJ, Anne PR, Kachnic LA, Rashid A, Watson JC, Mitchell EP, Pollock J, Lee RJ, Haddock M, Erickson BA, Willett CG.

Int J Radiat Oncol Biol Phys. 2015 Jan 1;91(1):116-23. doi: 10.1016/j.ijrobp.2014.09.031. Epub 2014 Nov 5.


Clinical and treatment factors associated with vaginal stenosis after definitive chemoradiation for anal canal cancer.

Mirabeau-Beale K, Hong TS, Niemierko A, Ancukiewicz M, Blaszkowsky LS, Crowley EM, Cusack JC, Drapek LC, Kovalchuk N, Markowski M, Napolitano B, Nyamwanda J, Ryan DP, Wolfgang J, Kachnic LA, Wo JY.

Pract Radiat Oncol. 2015 May-Jun;5(3):e113-8. doi: 10.1016/j.prro.2014.09.003. Epub 2014 Oct 30.


Medical student mentorship in radiation oncology at a single academic institution: A 10-year analysis.

Hirsch AE, Agarwal A, Rand AE, DeNunzio NJ, Patel KR, Truong MT, Russo GA, Kachnic LA.

Pract Radiat Oncol. 2015 May-Jun;5(3):e163-8. doi: 10.1016/j.prro.2014.08.005. Epub 2014 Sep 12.


The impact of race in male breast cancer treatment and outcome in the United States: a population-based analysis of 4,279 patients.

Shin JY, Kachnic LA, Hirsch AE.

Int J Breast Cancer. 2014;2014:685842. doi: 10.1155/2014/685842. Epub 2014 Oct 2.


FDG PET/CT in the management of colorectal and anal cancers.

Agarwal A, Marcus C, Xiao J, Nene P, Kachnic LA, Subramaniam RM.

AJR Am J Roentgenol. 2014 Nov;203(5):1109-19. doi: 10.2214/AJR.13.12256. Review.


Bending the cost curve: a unique collaboration between radiation oncologists and Blue Cross Blue Shield of Massachusetts to optimize the use of advanced technology.

Steingisser L, Acker B, Berman S, Brenner MJ, Bornstein BA, Busse P, FitzGerald TJ, Jacobson JO, Jekowsky E, Kachnic LA, Mamon H, McKee A, Shulman LN, Stevenson MA, Wazer D, Fallon JA.

J Oncol Pract. 2014 Sep;10(5):e321-7. doi: 10.1200/JOP.2014.001473.


Race disparities attributed to volumetric tumor burden in patients with head and neck cancer treated with radiotherapy.

Qureshi MM, Romesser PB, Ajani A, Kachnic LA, Jalisi S, Truong MT.

Head Neck. 2016 Jan;38(1):126-34. doi: 10.1002/hed.23863. Epub 2015 Jun 16.


The influence of limited English proficiency on outcome in patients treated with radiotherapy for head and neck cancer.

Qureshi MM, Romesser PB, Jalisi S, Zaner KS, Cooley TP, Grillone G, Kachnic LA, Truong MT.

Patient Educ Couns. 2014 Nov;97(2):276-82. doi: 10.1016/j.pec.2014.07.031. Epub 2014 Aug 11.


Consequences of anorectal cancer atlas implementation in the cooperative group setting: radiobiologic analysis of a prospective randomized in silico target delineation study.

Mavroidis P, Giantsoudis D, Awan MJ, Nijkamp J, Rasch CR, Duppen JC, Thomas CR Jr, Okunieff P, Jones WE 3rd, Kachnic LA, Papanikolaou N, Fuller CD; Southwest Oncology Group Radiation Oncology Committee.

Radiother Oncol. 2014 Sep;112(3):418-24. doi: 10.1016/j.radonc.2014.05.011. Epub 2014 Jul 1.


Upper abdominal normal organ contouring guidelines and atlas: a Radiation Therapy Oncology Group consensus.

Jabbour SK, Hashem SA, Bosch W, Kim TK, Finkelstein SE, Anderson BM, Ben-Josef E, Crane CH, Goodman KA, Haddock MG, Herman JM, Hong TS, Kachnic LA, Mamon HJ, Pantarotto JR, Dawson LA.

Pract Radiat Oncol. 2014 Mar-Apr;4(2):82-89. doi: 10.1016/j.prro.2013.06.004. Epub 2013 Aug 7.


RTOG 0631 phase 2/3 study of image guided stereotactic radiosurgery for localized (1-3) spine metastases: phase 2 results.

Ryu S, Pugh SL, Gerszten PC, Yin FF, Timmerman RD, Hitchcock YJ, Movsas B, Kanner AA, Berk LB, Followill DS, Kachnic LA.

Pract Radiat Oncol. 2014 Mar-Apr;4(2):76-81. doi: 10.1016/j.prro.2013.05.001. Epub 2013 Jun 4.


Long-term cosmetic outcomes and toxicities of proton beam therapy compared with photon-based 3-dimensional conformal accelerated partial-breast irradiation: a phase 1 trial.

Galland-Girodet S, Pashtan I, MacDonald SM, Ancukiewicz M, Hirsch AE, Kachnic LA, Specht M, Gadd M, Smith BL, Powell SN, Recht A, Taghian AG.

Int J Radiat Oncol Biol Phys. 2014 Nov 1;90(3):493-500. doi: 10.1016/j.ijrobp.2014.04.008. Epub 2014 May 29.


ASCO GI: 2014 symposium highlights.

Kachnic LA.

Oncology (Williston Park). 2014 Feb;28(2):150, 152. No abstract available.


Tadalafil for prevention of erectile dysfunction after radiotherapy for prostate cancer: the Radiation Therapy Oncology Group [0831] randomized clinical trial.

Pisansky TM, Pugh SL, Greenberg RE, Pervez N, Reed DR, Rosenthal SA, Mowat RB, Raben A, Buyyounouski MK, Kachnic LA, Bruner DW.

JAMA. 2014 Apr 2;311(13):1300-7. doi: 10.1001/jama.2014.2626.


Can patient comorbidities be included in clinical performance measures for radiation oncology?

Owen JB, Khalid N, Ho A, Kachnic LA, Komaki R, Tao ML, Currey A, Wilson JF.

J Oncol Pract. 2014 May;10(3):e175-81. doi: 10.1200/JOP.2013.001143. Epub 2014 Mar 18.


The impact of concurrent granulocyte-macrophage colony-stimulating factor on quality of life in head and neck cancer patients: results of the randomized, placebo-controlled Radiation Therapy Oncology Group 9901 trial.

Hoffman KE, Pugh SL, James JL, Scarantino C, Movsas B, Valicenti RK, Fortin A, Pollock J, Kim H, Brachman DG, Berk LB, Bruner DW, Kachnic LA.

Qual Life Res. 2014 Aug;23(6):1841-58. doi: 10.1007/s11136-014-0628-5. Epub 2014 Feb 4.


Challenges in the delivery of quality breast cancer care: initiation of adjuvant hormone therapy at an urban safety net hospital.

Crowley MM, McCoy ME, Bak SM, Caron SE, Ko NY, Kachnic LA, Alvis F, Battaglia TA.

J Oncol Pract. 2014 Mar;10(2):e107-12. doi: 10.1200/JOP.2013.001164. Epub 2013 Dec 17.


Acute gastrointestinal toxicity and tumor response with preoperative intensity modulated radiation therapy for rectal cancer.

Parekh A, Truong MT, Pashtan I, Qureshi MM, Martin NE, Nawaz O, Cerda S, Willins J, Hartshorn KL, Kachnic LA.

Gastrointest Cancer Res. 2013 Sep;6(5-6):137-43.


RTOG 0518: randomized phase III trial to evaluate zoledronic acid for prevention of osteoporosis and associated fractures in prostate cancer patients.

Kachnic LA, Pugh SL, Tai P, Smith M, Gore E, Shah AB, Martin AG, Kim HE, Nabid A, Lawton CA.

Prostate Cancer Prostatic Dis. 2013 Dec;16(4):382-6. doi: 10.1038/pcan.2013.35. Epub 2013 Oct 1.


Localized therapy for male breast cancer: functional advantages with comparable outcomes using breast conservation.

Fogh S, Kachnic LA, Goldberg SI, Taghian AG, Powell SN, Hirsch AE.

Clin Breast Cancer. 2013 Oct;13(5):344-9. doi: 10.1016/j.clbc.2013.05.004. Epub 2013 Jul 26.


Chemoradiation therapy: localized esophageal, gastric, and pancreatic cancer.

Pretz JL, Wo JY, Mamon HJ, Kachnic LA, Hong TS.

Surg Oncol Clin N Am. 2013 Jul;22(3):511-24. doi: 10.1016/j.soc.2013.02.005. Epub 2013 Mar 21. Review.


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