Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 206

1.

Moving Encounters: Actin Treadmilling in the Brush Border.

Kachar B.

Dev Cell. 2019 Sep 9;50(5):529-530. doi: 10.1016/j.devcel.2019.08.011.

PMID:
31505173
2.

Dynamic polyhedral actomyosin lattices remodel micron-scale curved membranes during exocytosis in live mice.

Ebrahim S, Chen D, Weiss M, Malec L, Ng Y, Rebustini I, Krystofiak E, Hu L, Liu J, Masedunskas A, Hardeman E, Gunning P, Kachar B, Weigert R.

Nat Cell Biol. 2019 Aug;21(8):933-939. doi: 10.1038/s41556-019-0365-7. Epub 2019 Jul 29.

PMID:
31358965
3.

Carbon replicas reveal double stranded structure of tight junctions in phase-contrast electron microscopy.

Krystofiak ES, Heymann JB, Kachar B.

Commun Biol. 2019 Mar 12;2:98. doi: 10.1038/s42003-019-0319-4. eCollection 2019.

4.

LMO7 deficiency reveals the significance of the cuticular plate for hearing function.

Du TT, Dewey JB, Wagner EL, Cui R, Heo J, Park JJ, Francis SP, Perez-Reyes E, Guillot SJ, Sherman NE, Xu W, Oghalai JS, Kachar B, Shin JB.

Nat Commun. 2019 Mar 8;10(1):1117. doi: 10.1038/s41467-019-09074-4.

5.

Multiple claudin-claudin cis interfaces are required for tight junction strand formation and inherent flexibility.

Zhao J, Krystofiak ES, Ballesteros A, Cui R, Van Itallie CM, Anderson JM, Fenollar-Ferrer C, Kachar B.

Commun Biol. 2018 May 17;1:50. doi: 10.1038/s42003-018-0051-5. eCollection 2018.

6.

Prestin Contributes to Membrane Compartmentalization and Is Required for Normal Innervation of Outer Hair Cells.

Takahashi S, Sun W, Zhou Y, Homma K, Kachar B, Cheatham MA, Zheng J.

Front Cell Neurosci. 2018 Jul 20;12:211. doi: 10.3389/fncel.2018.00211. eCollection 2018.

7.

Characterization of a novel MYO3A missense mutation associated with a dominant form of late onset hearing loss.

Dantas VGL, Raval MH, Ballesteros A, Cui R, Gunther LK, Yamamoto GL, Alves LU, Bueno AS, Lezirovitz K, Pirana S, Mendes BCA, Yengo CM, Kachar B, Mingroni-Netto RC.

Sci Rep. 2018 Jun 7;8(1):8706. doi: 10.1038/s41598-018-26818-2.

8.

Variable number of TMC1-dependent mechanotransducer channels underlie tonotopic conductance gradients in the cochlea.

Beurg M, Cui R, Goldring AC, Ebrahim S, Fettiplace R, Kachar B.

Nat Commun. 2018 Jun 5;9(1):2185. doi: 10.1038/s41467-018-04589-8.

9.

The presynaptic ribbon maintains vesicle populations at the hair cell afferent fiber synapse.

Becker L, Schnee ME, Niwa M, Sun W, Maxeiner S, Talaei S, Kachar B, Rutherford MA, Ricci AJ.

Elife. 2018 Jan 12;7. pii: e30241. doi: 10.7554/eLife.30241.

10.

Corrigendum: Stereocilia-staircase spacing is influenced by myosin III motors and their cargos espin-1 and espin-like.

Ebrahim S, Avenarius MR, Grati M, Krey JF, Windsor AM, Sousa AD, Ballesteros A, Cui R, Millis BA, Salles FT, Baird MA, Davidson MW, Jones SM, Choi D, Dong L, Raval MH, Yengo CM, Barr-Gillespie PG, Kachar B.

Nat Commun. 2017 Aug 14;8:16133. doi: 10.1038/ncomms16133.

11.

Maturation arrest in early postnatal sensory receptors by deletion of the miR-183/96/182 cluster in mouse.

Fan J, Jia L, Li Y, Ebrahim S, May-Simera H, Wood A, Morell RJ, Liu P, Lei J, Kachar B, Belluscio L, Qian H, Li T, Li W, Wistow G, Dong L.

Proc Natl Acad Sci U S A. 2017 May 23;114(21):E4271-E4280. doi: 10.1073/pnas.1619442114. Epub 2017 May 8.

12.

Plastin 1 widens stereocilia by transforming actin filament packing from hexagonal to liquid.

Krey JF, Krystofiak ES, Dumont RA, Vijayakumar S, Choi D, Rivero F, Kachar B, Jones SM, Barr-Gillespie PG.

J Cell Biol. 2016 Nov 21;215(4):467-482. Epub 2016 Nov 3.

13.

Impact of the Motor and Tail Domains of Class III Myosins on Regulating the Formation and Elongation of Actin Protrusions.

Raval MH, Quintero OA, Weck ML, Unrath WC, Gallagher JW, Cui R, Kachar B, Tyska MJ, Yengo CM.

J Biol Chem. 2016 Oct 21;291(43):22781-22792. Epub 2016 Aug 31.

14.

Hemi-fused structure mediates and controls fusion and fission in live cells.

Zhao WD, Hamid E, Shin W, Wen PJ, Krystofiak ES, Villarreal SA, Chiang HC, Kachar B, Wu LG.

Nature. 2016 Jun 23;534(7608):548-52. doi: 10.1038/nature18598. Epub 2016 Jun 15.

15.

Characterization of ATPase Activity of P2RX2 Cation Channel.

Mittal R, Grati M, Sedlacek M, Yuan F, Chang Q, Yan D, Lin X, Kachar B, Farooq A, Chapagain P, Zhang Y, Liu XZ.

Front Physiol. 2016 May 24;7:186. doi: 10.3389/fphys.2016.00186. eCollection 2016.

16.

Alternative Splice Forms Influence Functions of Whirlin in Mechanosensory Hair Cell Stereocilia.

Ebrahim S, Ingham NJ, Lewis MA, Rogers MJC, Cui R, Kachar B, Pass JC, Steel KP.

Cell Rep. 2016 May 3;15(5):935-943. doi: 10.1016/j.celrep.2016.03.081. Epub 2016 Apr 21.

17.

Stereocilia-staircase spacing is influenced by myosin III motors and their cargos espin-1 and espin-like.

Ebrahim S, Avenarius MR, Grati M, Krey JF, Windsor AM, Sousa AD, Ballesteros A, Cui R, Millis BA, Salles FT, Baird MA, Davidson MW, Jones SM, Choi D, Dong L, Raval MH, Yengo CM, Barr-Gillespie PG, Kachar B.

Nat Commun. 2016 Mar 1;7:10833. doi: 10.1038/ncomms10833. Erratum in: Nat Commun. 2017 Aug 14;8:16133.

18.

Tectorins crosslink type II collagen fibrils and connect the tectorial membrane to the spiral limbus.

Andrade LR, Salles FT, Grati M, Manor U, Kachar B.

J Struct Biol. 2016 May;194(2):139-46. doi: 10.1016/j.jsb.2016.01.006. Epub 2016 Jan 13.

19.

Self-organization of waves and pulse trains by molecular motors in cellular protrusions.

Yochelis A, Ebrahim S, Millis B, Cui R, Kachar B, Naoz M, Gov NS.

Sci Rep. 2015 Sep 3;5:13521. doi: 10.1038/srep13521.

20.

TMC1 and TMC2 Localize at the Site of Mechanotransduction in Mammalian Inner Ear Hair Cell Stereocilia.

Kurima K, Ebrahim S, Pan B, Sedlacek M, Sengupta P, Millis BA, Cui R, Nakanishi H, Fujikawa T, Kawashima Y, Choi BY, Monahan K, Holt JR, Griffith AJ, Kachar B.

Cell Rep. 2015 Sep 8;12(10):1606-17. doi: 10.1016/j.celrep.2015.07.058. Epub 2015 Aug 28.

21.

A complex of ZO-1 and the BAR-domain protein TOCA-1 regulates actin assembly at the tight junction.

Van Itallie CM, Tietgens AJ, Krystofiak E, Kachar B, Anderson JM.

Mol Biol Cell. 2015 Aug 1;26(15):2769-87. doi: 10.1091/mbc.E15-04-0232. Epub 2015 Jun 10.

22.

A short splice form of Xin-actin binding repeat containing 2 (XIRP2) lacking the Xin repeats is required for maintenance of stereocilia morphology and hearing function.

Francis SP, Krey JF, Krystofiak ES, Cui R, Nanda S, Xu W, Kachar B, Barr-Gillespie PG, Shin JB.

J Neurosci. 2015 Feb 4;35(5):1999-2014. doi: 10.1523/JNEUROSCI.3449-14.2015.

23.

Inner ear tissue preservation by rapid freezing: improving fixation by high-pressure freezing and hybrid methods.

Bullen A, Taylor RR, Kachar B, Moores C, Fleck RA, Forge A.

Hear Res. 2014 Sep;315:49-60. doi: 10.1016/j.heares.2014.06.006. Epub 2014 Jul 10.

24.

Specialized postsynaptic morphology enhances neurotransmitter dilution and high-frequency signaling at an auditory synapse.

Graydon CW, Cho S, Diamond JS, Kachar B, von Gersdorff H, Grimes WN.

J Neurosci. 2014 Jun 11;34(24):8358-72. doi: 10.1523/JNEUROSCI.4493-13.2014.

25.

Localization of kainate receptors in inner and outer hair cell synapses.

Fujikawa T, Petralia RS, Fitzgerald TS, Wang YX, Millis B, Morgado-Díaz JA, Kitamura K, Kachar B.

Hear Res. 2014 Aug;314:20-32. doi: 10.1016/j.heares.2014.05.001. Epub 2014 May 21.

26.

Intestinal brush border assembly driven by protocadherin-based intermicrovillar adhesion.

Crawley SW, Shifrin DA Jr, Grega-Larson NE, McConnell RE, Benesh AE, Mao S, Zheng Y, Zheng QY, Nam KT, Millis BA, Kachar B, Tyska MJ.

Cell. 2014 Apr 10;157(2):433-446. doi: 10.1016/j.cell.2014.01.067.

27.

Superresolution imaging with standard fluorescent probes.

Millis BA, Burnette DT, Lippincott-Schwartz J, Kachar B.

Curr Protoc Cell Biol. 2013 Sep 24;60:Unit 21.8.. doi: 10.1002/0471143030.cb2108s60.

28.

Correlation of actin crosslinker and capper expression levels with stereocilia growth phases.

Avenarius MR, Saylor KW, Lundeberg MR, Wilmarth PA, Shin JB, Spinelli KJ, Pagana JM, Andrade L, Kachar B, Choi D, David LL, Barr-Gillespie PG.

Mol Cell Proteomics. 2014 Feb;13(2):606-20. doi: 10.1074/mcp.M113.033704. Epub 2013 Dec 7.

29.

Inhibitory and multisynaptic spines, and hemispherical synaptic specialization in the posterodorsal medial amygdala of male and female rats.

Brusco J, Merlo S, Ikeda ÉT, Petralia RS, Kachar B, Rasia-Filho AA, Moreira JE.

J Comp Neurol. 2014 Jun 15;522(9):2075-88. doi: 10.1002/cne.23518.

30.

CLIC5 stabilizes membrane-actin filament linkages at the base of hair cell stereocilia in a molecular complex with radixin, taperin, and myosin VI.

Salles FT, Andrade LR, Tanda S, Grati M, Plona KL, Gagnon LH, Johnson KR, Kachar B, Berryman MA.

Cytoskeleton (Hoboken). 2014 Jan;71(1):61-78. doi: 10.1002/cm.21159. Epub 2013 Dec 10.

31.

Myosin 3A kinase activity is regulated by phosphorylation of the kinase domain activation loop.

Quintero OA, Unrath WC, Stevens SM Jr, Manor U, Kachar B, Yengo CM.

J Biol Chem. 2013 Dec 27;288(52):37126-37. doi: 10.1074/jbc.M113.511014. Epub 2013 Nov 10.

32.

Linking actin networks and cell membrane via a reaction-diffusion-elastic description of nonlinear filopodia initiation.

Ben Isaac E, Manor U, Kachar B, Yochelis A, Gov NS.

Phys Rev E Stat Nonlin Soft Matter Phys. 2013 Aug;88(2):022718. Epub 2013 Aug 29.

PMID:
24032875
33.

Whirlin, a cytoskeletal scaffolding protein, stabilizes the paranodal region and axonal cytoskeleton in myelinated axons.

Green JA, Yang J, Grati M, Kachar B, Bhat MA.

BMC Neurosci. 2013 Sep 6;14:96. doi: 10.1186/1471-2202-14-96.

34.

Myosin transcellular networks regulate epithelial apical geometry.

Ebrahim S, Kachar B.

Cell Cycle. 2013 Sep 15;12(18):2931-2. doi: 10.4161/cc.26229. Epub 2013 Aug 23. No abstract available.

35.

Progressive hearing loss and gradual deterioration of sensory hair bundles in the ears of mice lacking the actin-binding protein Eps8L2.

Furness DN, Johnson SL, Manor U, Rüttiger L, Tocchetti A, Offenhauser N, Olt J, Goodyear RJ, Vijayakumar S, Dai Y, Hackney CM, Franz C, Di Fiore PP, Masetto S, Jones SM, Knipper M, Holley MC, Richardson GP, Kachar B, Marcotti W.

Proc Natl Acad Sci U S A. 2013 Aug 20;110(34):13898-903. doi: 10.1073/pnas.1304644110. Epub 2013 Aug 5.

36.

NMII forms a contractile transcellular sarcomeric network to regulate apical cell junctions and tissue geometry.

Ebrahim S, Fujita T, Millis BA, Kozin E, Ma X, Kawamoto S, Baird MA, Davidson M, Yonemura S, Hisa Y, Conti MA, Adelstein RS, Sakaguchi H, Kachar B.

Curr Biol. 2013 Apr 22;23(8):731-6. doi: 10.1016/j.cub.2013.03.039. Epub 2013 Apr 4.

37.

Mutation of the ATP-gated P2X(2) receptor leads to progressive hearing loss and increased susceptibility to noise.

Yan D, Zhu Y, Walsh T, Xie D, Yuan H, Sirmaci A, Fujikawa T, Wong AC, Loh TL, Du L, Grati M, Vlajkovic SM, Blanton S, Ryan AF, Chen ZY, Thorne PR, Kachar B, Tekin M, Zhao HB, Housley GD, King MC, Liu XZ.

Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):2228-33. doi: 10.1073/pnas.1222285110. Epub 2013 Jan 23.

38.

Cryo-electron tomography of the magnetotactic vibrio Magnetovibrio blakemorei: insights into the biomineralization of prismatic magnetosomes.

Abreu F, Sousa AA, Aronova MA, Kim Y, Cox D, Leapman RD, Andrade LR, Kachar B, Bazylinski DA, Lins U.

J Struct Biol. 2013 Feb;181(2):162-8. doi: 10.1016/j.jsb.2012.12.002. Epub 2012 Dec 12.

39.

Localization of PDZD7 to the stereocilia ankle-link associates this scaffolding protein with the Usher syndrome protein network.

Grati M, Shin JB, Weston MD, Green J, Bhat MA, Gillespie PG, Kachar B.

J Neurosci. 2012 Oct 10;32(41):14288-93. doi: 10.1523/JNEUROSCI.3071-12.2012.

40.

Competition and compensation: dissecting the biophysical and functional differences between the class 3 myosin paralogs, myosins 3a and 3b.

Manor U, Grati M, Yengo CM, Kachar B, Gov NS.

Bioarchitecture. 2012 Sep-Oct;2(5):171-4. doi: 10.4161/bioa.21733. Epub 2012 Sep 1.

41.

Immunogold TEM of otoconin 90 and otolin - relevance to mineralization of otoconia, and pathogenesis of benign positional vertigo.

Andrade LR, Lins U, Farina M, Kachar B, Thalmann R.

Hear Res. 2012 Oct;292(1-2):14-25. doi: 10.1016/j.heares.2012.07.003. Epub 2012 Jul 25.

42.

Myosin IIIB uses an actin-binding motif in its espin-1 cargo to reach the tips of actin protrusions.

Merritt RC, Manor U, Salles FT, Grati M, Dose AC, Unrath WC, Quintero OA, Yengo CM, Kachar B.

Curr Biol. 2012 Feb 21;22(4):320-5. doi: 10.1016/j.cub.2011.12.053. Epub 2012 Jan 19.

43.

Bleaching/blinking assisted localization microscopy for superresolution imaging using standard fluorescent molecules.

Burnette DT, Sengupta P, Dai Y, Lippincott-Schwartz J, Kachar B.

Proc Natl Acad Sci U S A. 2011 Dec 27;108(52):21081-6. doi: 10.1073/pnas.1117430109. Epub 2011 Dec 13.

44.

Sharp Ca²⁺ nanodomains beneath the ribbon promote highly synchronous multivesicular release at hair cell synapses.

Graydon CW, Cho S, Li GL, Kachar B, von Gersdorff H.

J Neurosci. 2011 Nov 16;31(46):16637-50. doi: 10.1523/JNEUROSCI.1866-11.2011.

45.

Mouse models of MYH9-related disease: mutations in nonmuscle myosin II-A.

Zhang Y, Conti MA, Malide D, Dong F, Wang A, Shmist YA, Liu C, Zerfas P, Daniels MP, Chan CC, Kozin E, Kachar B, Kelley MJ, Kopp JB, Adelstein RS.

Blood. 2012 Jan 5;119(1):238-50. doi: 10.1182/blood-2011-06-358853. Epub 2011 Sep 8.

46.

Myosin VIIa and sans localization at stereocilia upper tip-link density implicates these Usher syndrome proteins in mechanotransduction.

Grati M, Kachar B.

Proc Natl Acad Sci U S A. 2011 Jul 12;108(28):11476-81. doi: 10.1073/pnas.1104161108. Epub 2011 Jun 27.

47.

Fluorescence recovery after photobleaching (FRAP) of fluorescence tagged proteins in dendritic spines of cultured hippocampal neurons.

Zheng CY, Petralia RS, Wang YX, Kachar B.

J Vis Exp. 2011 Apr 16;(50). pii: 2568. doi: 10.3791/2568.

48.

Differential localization of SAP102 and PSD-95 is revealed in hippocampal spines using super-resolution light microscopy.

Zheng CY, Wang YX, Kachar B, Petralia RS.

Commun Integr Biol. 2011 Jan;4(1):104-5. doi: 10.4161/cib.4.1.14172.

49.

Regulation of PCDH15 function in mechanosensory hair cells by alternative splicing of the cytoplasmic domain.

Webb SW, Grillet N, Andrade LR, Xiong W, Swarthout L, Della Santina CC, Kachar B, Müller U.

Development. 2011 Apr;138(8):1607-17. doi: 10.1242/dev.060061.

50.

A role for actin arcs in the leading-edge advance of migrating cells.

Burnette DT, Manley S, Sengupta P, Sougrat R, Davidson MW, Kachar B, Lippincott-Schwartz J.

Nat Cell Biol. 2011 Apr;13(4):371-81. doi: 10.1038/ncb2205. Epub 2011 Mar 20.

Supplemental Content

Loading ...
Support Center