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Items: 14

1.

Ontogeny, distribution and potential roles of 5-hydroxymethylcytosine in human liver function.

Ivanov M, Kals M, Kacevska M, Barragan I, Kasuga K, Rane A, Metspalu A, Milani L, Ingelman-Sundberg M.

Genome Biol. 2013 Aug 19;14(8):R83. doi: 10.1186/gb-2013-14-8-r83.

2.

Extra-hepatic cancer represses hepatic drug metabolism via interleukin (IL)-6 signalling.

Kacevska M, Mahns A, Sharma R, Clarke SJ, Robertson GR, Liddle C.

Pharm Res. 2013 Sep;30(9):2270-8. doi: 10.1007/s11095-013-1042-3. Epub 2013 Apr 20.

PMID:
23604979
3.

In-solution hybrid capture of bisulfite-converted DNA for targeted bisulfite sequencing of 174 ADME genes.

Ivanov M, Kals M, Kacevska M, Metspalu A, Ingelman-Sundberg M, Milani L.

Nucleic Acids Res. 2013 Apr 1;41(6):e72. doi: 10.1093/nar/gks1467. Epub 2013 Jan 15.

4.

Epigenomics and interindividual differences in drug response.

Ivanov M, Kacevska M, Ingelman-Sundberg M.

Clin Pharmacol Ther. 2012 Dec;92(6):727-36. doi: 10.1038/clpt.2012.152. Epub 2012 Oct 24. Review.

PMID:
23093317
5.

Pharmacogenomics of drug-metabolizing enzymes: a recent update on clinical implications and endogenous effects.

Sim SC, Kacevska M, Ingelman-Sundberg M.

Pharmacogenomics J. 2013 Feb;13(1):1-11. doi: 10.1038/tpj.2012.45. Epub 2012 Oct 23. Review.

PMID:
23089672
6.

Hepatic fat loss in advanced nonalcoholic steatohepatitis: are alterations in serum adiponectin the cause?

van der Poorten D, Samer CF, Ramezani-Moghadam M, Coulter S, Kacevska M, Schrijnders D, Wu LE, McLeod D, Bugianesi E, Komuta M, Roskams T, Liddle C, Hebbard L, George J.

Hepatology. 2013 Jun;57(6):2180-8. doi: 10.1002/hep.26072. Epub 2013 Jan 18.

7.

Epigenetic-dependent regulation of drug transport and metabolism: an update.

Kacevska M, Ivanov M, Ingelman-Sundberg M.

Pharmacogenomics. 2012 Sep;13(12):1373-85. doi: 10.2217/pgs.12.119. Review.

PMID:
22966887
8.

DNA methylation dynamics in the hepatic CYP3A4 gene promoter.

Kacevska M, Ivanov M, Wyss A, Kasela S, Milani L, Rane A, Ingelman-Sundberg M.

Biochimie. 2012 Nov;94(11):2338-44. doi: 10.1016/j.biochi.2012.07.013. Epub 2012 Jul 31.

PMID:
22906825
9.

Perspectives on epigenetics and its relevance to adverse drug reactions.

Kacevska M, Ivanov M, Ingelman-Sundberg M.

Clin Pharmacol Ther. 2011 Jun;89(6):902-7. doi: 10.1038/clpt.2011.21. Epub 2011 Apr 20. Review. No abstract available.

PMID:
21508940
10.

Extrahepatic cancer suppresses nuclear receptor-regulated drug metabolism.

Kacevska M, Downes MR, Sharma R, Evans RM, Clarke SJ, Liddle C, Robertson GR.

Clin Cancer Res. 2011 May 15;17(10):3170-80. doi: 10.1158/1078-0432.CCR-10-3289. Epub 2011 Apr 15.

11.

Systemic inflammatory response predicts prognosis in patients with advanced-stage colorectal cancer.

Sharma R, Zucknick M, London R, Kacevska M, Liddle C, Clarke SJ.

Clin Colorectal Cancer. 2008 Sep;7(5):331-7. doi: 10.3816/CCC.2008.n.044.

PMID:
18794066
12.

Inflammation and CYP3A4-mediated drug metabolism in advanced cancer: impact and implications for chemotherapeutic drug dosing.

Kacevska M, Robertson GR, Clarke SJ, Liddle C.

Expert Opin Drug Metab Toxicol. 2008 Feb;4(2):137-49. doi: 10.1517/17425255.4.2.137. Review.

PMID:
18248309
13.

Regulation of drug-metabolizing enzymes and transporters in infection, inflammation, and cancer.

Morgan ET, Goralski KB, Piquette-Miller M, Renton KW, Robertson GR, Chaluvadi MR, Charles KA, Clarke SJ, Kacevska M, Liddle C, Richardson TA, Sharma R, Sinal CJ.

Drug Metab Dispos. 2008 Feb;36(2):205-16. doi: 10.1124/dmd.107.018747.

PMID:
18218849
14.

Downregulation of drug transport and metabolism in mice bearing extra-hepatic malignancies.

Sharma R, Kacevska M, London R, Clarke SJ, Liddle C, Robertson G.

Br J Cancer. 2008 Jan 15;98(1):91-7. Epub 2007 Dec 4.

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