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Items: 1 to 50 of 152

1.

A model for estimating the lifelong exposure to PM2.5 and NO2 and the application to population studies.

Li N, Maesano CN, Friedrich R, Medda E, Brandstetter S, Kabesch M, Apfelbacher C, Melter M, Seelbach-Göbel B, Annesi-Maesano I, Sarigiannis D; KUNO-Kids study group.

Environ Res. 2019 Nov;178:108629. doi: 10.1016/j.envres.2019.108629. Epub 2019 Aug 16.

PMID:
31476682
2.

Nocturnal asthma is affected by genetic interactions between RORA and NPSR1.

Gaertner VD, Michel S, Curtin JA, Pulkkinen V, Acevedo N, Söderhäll C, von Berg A, Bufe A, Laub O, Rietschel E, Heinzmann A, Simma B, Vogelberg C, Pershagen G, Melén E, Simpson A, Custovic A, Kere J, Kabesch M.

Pediatr Pulmonol. 2019 Jun;54(6):847-857. doi: 10.1002/ppul.24292. Epub 2019 Mar 29.

PMID:
30927345
3.

Genome-wide association study of inhaled corticosteroid response in admixed children with asthma.

Hernandez-Pacheco N, Farzan N, Francis B, Karimi L, Repnik K, Vijverberg SJ, Soares P, Schieck M, Gorenjak M, Forno E, Eng C, Oh SS, Pérez-Méndez L, Berce V, Tavendale R, Samedy LA, Hunstman S, Hu D, Meade K, Farber HJ, Avila PC, Serebrisky D, Thyne SM, Brigino-Buenaventura E, Rodriguez-Cintron W, Sen S, Kumar R, Lenoir M, Rodriguez-Santana JR, Celedón JC, Mukhopadhyay S, Potočnik U, Pirmohamed M, Verhamme KM, Kabesch M, Palmer CNA, Hawcutt DB, Flores C, Maitland-van der Zee AH, Burchard EG, Pino-Yanes M.

Clin Exp Allergy. 2019 Jun;49(6):789-798. doi: 10.1111/cea.13354. Epub 2019 Feb 15.

PMID:
30697902
4.

KUNO-Kids birth cohort study: rationale, design, and cohort description.

Brandstetter S, Toncheva AA, Niggel J, Wolff C, Gran S, Seelbach-Göbel B, Apfelbacher C, Melter M, Kabesch M; KUNO-Kids study group.

Mol Cell Pediatr. 2019 Jan 9;6(1):1. doi: 10.1186/s40348-018-0088-z.

5.

Author Correction: Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis.

Waage J, Standl M, Curtin JA, Jessen LE, Thorsen J, Tian C, Schoettler N; 23andMe Research Team; AAGC collaborators, Flores C, Abdellaoui A, Ahluwalia TS, Alves AC, Amaral AFS, Antó JM, Arnold A, Barreto-Luis A, Baurecht H, van Beijsterveldt CEM, Bleecker ER, Bonàs-Guarch S, Boomsma DI, Brix S, Bunyavanich S, Burchard EG, Chen Z, Curjuric I, Custovic A, den Dekker HT, Dharmage SC, Dmitrieva J, Duijts L, Ege MJ, Gauderman WJ, Georges M, Gieger C, Gilliland F, Granell R, Gui H, Hansen T, Heinrich J, Henderson J, Hernandez-Pacheco N, Holt P, Imboden M, Jaddoe VWV, Jarvelin MR, Jarvis DL, Jensen KK, Jónsdóttir I, Kabesch M, Kaprio J, Kumar A, Lee YA, Levin AM, Li X, Lorenzo-Diaz F, Melén E, Mercader JM, Meyers DA, Myers R, Nicolae DL, Nohr EA, Palviainen T, Paternoster L, Pennell CE, Pershagen G, Pino-Yanes M, Probst-Hensch NM, Rüschendorf F, Simpson A, Stefansson K, Sunyer J, Sveinbjornsson G, Thiering E, Thompson PJ, Torrent M, Torrents D, Tung JY, Wang CA, Weidinger S, Weiss S, Willemsen G, Williams LK, Ober C, Hinds DA, Ferreira MA, Bisgaard H, Strachan DP, Bønnelykke K.

Nat Genet. 2018 Sep;50(9):1343. doi: 10.1038/s41588-018-0197-6.

PMID:
30116036
6.

Protective effects of breastfeeding on respiratory symptoms in infants with 17q21 asthma risk variants.

Gorlanova O, Illi S, Toncheva AA, Usemann J, Latzin P, Kabesch M, Dalphin JC, Lauener R, Pekkanen JR, Von Mutius E, Riedler J, Kuehni CE, Röösli M, Frey U; BILD and PASTURE study groups.

Allergy. 2018 Dec;73(12):2388-2392. doi: 10.1111/all.13568. Epub 2018 Aug 9. No abstract available.

PMID:
30030842
7.

Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis.

Waage J, Standl M, Curtin JA, Jessen LE, Thorsen J, Tian C, Schoettler N; 23andMe Research Team; AAGC collaborators, Flores C, Abdellaoui A, Ahluwalia TS, Alves AC, Amaral AFS, Antó JM, Arnold A, Barreto-Luis A, Baurecht H, van Beijsterveldt CEM, Bleecker ER, Bonàs-Guarch S, Boomsma DI, Brix S, Bunyavanich S, Burchard EG, Chen Z, Curjuric I, Custovic A, den Dekker HT, Dharmage SC, Dmitrieva J, Duijts L, Ege MJ, Gauderman WJ, Georges M, Gieger C, Gilliland F, Granell R, Gui H, Hansen T, Heinrich J, Henderson J, Hernandez-Pacheco N, Holt P, Imboden M, Jaddoe VWV, Jarvelin MR, Jarvis DL, Jensen KK, Jónsdóttir I, Kabesch M, Kaprio J, Kumar A, Lee YA, Levin AM, Li X, Lorenzo-Diaz F, Melén E, Mercader JM, Meyers DA, Myers R, Nicolae DL, Nohr EA, Palviainen T, Paternoster L, Pennell CE, Pershagen G, Pino-Yanes M, Probst-Hensch NM, Rüschendorf F, Simpson A, Stefansson K, Sunyer J, Sveinbjornsson G, Thiering E, Thompson PJ, Torrent M, Torrents D, Tung JY, Wang CA, Weidinger S, Weiss S, Willemsen G, Williams LK, Ober C, Hinds DA, Ferreira MA, Bisgaard H, Strachan DP, Bønnelykke K.

Nat Genet. 2018 Aug;50(8):1072-1080. doi: 10.1038/s41588-018-0157-1. Epub 2018 Jul 16. Erratum in: Nat Genet. 2018 Sep;50(9):1343.

8.

17q21 variant increases the risk of exacerbations in asthmatic children despite inhaled corticosteroids use.

Farzan N, Vijverberg SJ, Hernandez-Pacheco N, Bel EHD, Berce V, Bønnelykke K, Bisgaard H, Burchard EG, Canino G, Celedón JC, Chew FT, Chiang WC, Cloutier MM, Forno E, Francis B, Hawcutt DB, Herrera-Luis E, Kabesch M, Karimi L, Melén E, Mukhopadhyay S, Merid SK, Palmer CN, Pino-Yanes M, Pirmohamed M, Potočnik U, Repnik K, Schieck M, Sevelsted A, Sio YY, Smyth RL, Soares P, Söderhäll C, Tantisira KG, Tavendale R, Tse SM, Turner S, Verhamme KM, Maitland-van der Zee AH.

Allergy. 2018 Oct;73(10):2083-2088. doi: 10.1111/all.13499. Epub 2018 Jul 9. No abstract available.

9.

The use of pharmacogenomics, epigenomics, and transcriptomics to improve childhood asthma management: Where do we stand?

Farzan N, Vijverberg SJ, Kabesch M, Sterk PJ, Maitland-van der Zee AH.

Pediatr Pulmonol. 2018 Jun;53(6):836-845. doi: 10.1002/ppul.23976. Epub 2018 Mar 1. Review.

PMID:
29493882
10.

Asthma- and IgE-associated polymorphisms affect expression of TH 17 genes.

Worth L, Michel S, Gaertner VD, Kabesch M, Schieck M.

Allergy. 2018 Jun;73(6):1342-1347. doi: 10.1111/all.13422. Epub 2018 Apr 10. No abstract available.

PMID:
29380867
11.

Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.

Demenais F, Margaritte-Jeannin P, Barnes KC, Cookson WOC, Altmüller J, Ang W, Barr RG, Beaty TH, Becker AB, Beilby J, Bisgaard H, Bjornsdottir US, Bleecker E, Bønnelykke K, Boomsma DI, Bouzigon E, Brightling CE, Brossard M, Brusselle GG, Burchard E, Burkart KM, Bush A, Chan-Yeung M, Chung KF, Couto Alves A, Curtin JA, Custovic A, Daley D, de Jongste JC, Del-Rio-Navarro BE, Donohue KM, Duijts L, Eng C, Eriksson JG, Farrall M, Fedorova Y, Feenstra B, Ferreira MA; Australian Asthma Genetics Consortium (AAGC) collaborators, Freidin MB, Gajdos Z, Gauderman J, Gehring U, Geller F, Genuneit J, Gharib SA, Gilliland F, Granell R, Graves PE, Gudbjartsson DF, Haahtela T, Heckbert SR, Heederik D, Heinrich J, Heliövaara M, Henderson J, Himes BE, Hirose H, Hirschhorn JN, Hofman A, Holt P, Hottenga J, Hudson TJ, Hui J, Imboden M, Ivanov V, Jaddoe VWV, James A, Janson C, Jarvelin MR, Jarvis D, Jones G, Jonsdottir I, Jousilahti P, Kabesch M, Kähönen M, Kantor DB, Karunas AS, Khusnutdinova E, Koppelman GH, Kozyrskyj AL, Kreiner E, Kubo M, Kumar R, Kumar A, Kuokkanen M, Lahousse L, Laitinen T, Laprise C, Lathrop M, Lau S, Lee YA, Lehtimäki T, Letort S, Levin AM, Li G, Liang L, Loehr LR, London SJ, Loth DW, Manichaikul A, Marenholz I, Martinez FJ, Matheson MC, Mathias RA, Matsumoto K, Mbarek H, McArdle WL, Melbye M, Melén E, Meyers D, Michel S, Mohamdi H, Musk AW, Myers RA, Nieuwenhuis MAE, Noguchi E, O'Connor GT, Ogorodova LM, Palmer CD, Palotie A, Park JE, Pennell CE, Pershagen G, Polonikov A, Postma DS, Probst-Hensch N, Puzyrev VP, Raby BA, Raitakari OT, Ramasamy A, Rich SS, Robertson CF, Romieu I, Salam MT, Salomaa V, Schlünssen V, Scott R, Selivanova PA, Sigsgaard T, Simpson A, Siroux V, Smith LJ, Solodilova M, Standl M, Stefansson K, Strachan DP, Stricker BH, Takahashi A, Thompson PJ, Thorleifsson G, Thorsteinsdottir U, Tiesler CMT, Torgerson DG, Tsunoda T, Uitterlinden AG, van der Valk RJP, Vaysse A, Vedantam S, von Berg A, von Mutius E, Vonk JM, Waage J, Wareham NJ, Weiss ST, White WB, Wickman M, Widén E, Willemsen G, Williams LK, Wouters IM, Yang JJ, Zhao JH, Moffatt MF, Ober C, Nicolae DL.

Nat Genet. 2018 Jan;50(1):42-53. doi: 10.1038/s41588-017-0014-7. Epub 2017 Dec 22.

12.

Asthmatic farm children show increased CD3+CD8low T-cells compared to non-asthmatic farm children.

Twardziok M, Schröder PC, Krusche J, Casaca VI, Illi S, Böck A, Loss GJ, Kabesch M, Toncheva AA, Roduit C, Depner M, Genuneit J, Renz H, Roponen M, Weber J, Braun-Fahrländer C, Riedler J, Lauener R, Vuitton DA, Dalphin JC, Pekkanen J, von Mutius E, Schaub B; PASTURE Study Group:, Hyvärinen A, Karvonen AM, Kirjavainen PV, Remes S, Kaulek V, Dalphin ML, Ege M, Pfefferle PI, Doekes G.

Clin Immunol. 2017 Oct;183:285-292. doi: 10.1016/j.clim.2017.09.009. Epub 2017 Sep 13. No abstract available.

PMID:
28917722
13.

Functional phenotypes determined by fluctuation-based clustering of lung function measurements in healthy and asthmatic cohort participants.

Delgado-Eckert E, Fuchs O, Kumar N, Pekkanen J, Dalphin JC, Riedler J, Lauener R, Kabesch M, Kupczyk M, Dahlen SE, Mutius EV, Frey U; PASTURE and BIOAIR Study groups.

Thorax. 2018 Feb;73(2):107-115. doi: 10.1136/thoraxjnl-2016-209919. Epub 2017 Sep 2.

PMID:
28866644
14.

Rationale and design of the multiethnic Pharmacogenomics in Childhood Asthma consortium.

Farzan N, Vijverberg SJ, Andiappan AK, Arianto L, Berce V, Blanca-López N, Bisgaard H, Bønnelykke K, Burchard EG, Campo P, Canino G, Carleton B, Celedón JC, Chew FT, Chiang WC, Cloutier MM, Daley D, Den Dekker HT, Dijk FN, Duijts L, Flores C, Forno E, Hawcutt DB, Hernandez-Pacheco N, de Jongste JC, Kabesch M, Koppelman GH, Manolopoulos VG, Melén E, Mukhopadhyay S, Nilsson S, Palmer CN, Pino-Yanes M, Pirmohamed M, Potočnik U, Raaijmakers JA, Repnik K, Schieck M, Sio YY, Smyth RL, Szalai C, Tantisira KG, Turner S, van der Schee MP, Verhamme KM, Maitland-van der Zee AH.

Pharmacogenomics. 2017 Jul;18(10):931-943. doi: 10.2217/pgs-2017-0035. Epub 2017 Jun 22.

15.

Phenotypes of Atopic Dermatitis Depending on the Timing of Onset and Progression in Childhood.

Roduit C, Frei R, Depner M, Karvonen AM, Renz H, Braun-Fahrländer C, Schmausser-Hechfellner E, Pekkanen J, Riedler J, Dalphin JC, von Mutius E, Lauener RP; the PASTURE study group, Hyvärinen A, Kirjavainen P, Remes S, Roponen M, Dalphin ML, Kaulek V, Ege M, Genuneit J, Illi S, Kabesch M, Schaub B, Pfefferle PI, Doekes G.

JAMA Pediatr. 2017 Jul 1;171(7):655-662. doi: 10.1001/jamapediatrics.2017.0556.

16.

Neuropeptide S (NPS) variants modify the signaling and risk effects of NPS Receptor 1 (NPSR1) variants in asthma.

Acevedo N, Ezer S, Kebede Merid S, Gaertner VD, Söderhäll C, D'Amato M, Kabesch M, Melén E, Kere J, Pulkkinen V.

PLoS One. 2017 May 2;12(5):e0176568. doi: 10.1371/journal.pone.0176568. eCollection 2017.

17.

6q12 and 11p14 variants are associated with postnatal exhaled nitric oxide levels and respiratory symptoms.

Fuchs O, Gorlanova O, Latzin P, Schmidt A, Schieck M, Toncheva AA, Michel S, Gaertner VD, Kabesch M, Frey U.

J Allergy Clin Immunol. 2017 Oct;140(4):1015-1023. doi: 10.1016/j.jaci.2016.11.048. Epub 2017 Jan 19.

PMID:
28109725
18.

IL-33 polymorphisms are associated with increased risk of hay fever and reduced regulatory T cells in a birth cohort.

Schröder PC, Casaca VI, Illi S, Schieck M, Michel S, Böck A, Roduit C, Frei R, Lluis A, Genuneit J, Pfefferle P, Roponen M, Weber J, Braun-Fahrländer C, Riedler J, Lauener R, Vuitton DA, Dalphin JC, Pekkanen J, von Mutius E, Kabesch M, Schaub B; PASTURE Study group.

Pediatr Allergy Immunol. 2016 Nov;27(7):687-695. doi: 10.1111/pai.12597. Epub 2016 Jul 12.

PMID:
27171815
19.

Early origins of asthma (and allergy).

Kabesch M.

Mol Cell Pediatr. 2016 Dec;3(1):31. doi: 10.1186/s40348-016-0056-4. Epub 2016 Aug 10. Review.

20.

Combining genomewide association study and lung eQTL analysis provides evidence for novel genes associated with asthma.

Nieuwenhuis MA, Siedlinski M, van den Berge M, Granell R, Li X, Niens M, van der Vlies P, Altmüller J, Nürnberg P, Kerkhof M, van Schayck OC, Riemersma RA, van der Molen T, de Monchy JG, Bossé Y, Sandford A, Bruijnzeel-Koomen CA, Gerth van Wijk R, Ten Hacken NH, Timens W, Boezen HM, Henderson J, Kabesch M, Vonk JM, Postma DS, Koppelman GH.

Allergy. 2016 Dec;71(12):1712-1720. doi: 10.1111/all.12990. Epub 2016 Aug 22.

21.

Unlike in Children with Allergic Asthma, IgE Transcripts from Preschool Children with Atopic Dermatitis Display Signs of Superantigen-Driven Activation.

Kerzel S, Rogosch T, Struecker B, Maier RF, Kabesch M, Zemlin M.

J Immunol. 2016 Jun 15;196(12):4885-92. doi: 10.4049/jimmunol.1402889. Epub 2016 May 9.

22.
23.

Neutrophilic superoxide production can assess pharmacological and pharmacogenetic β-adrenoreceptor effects.

Reinartz MT, Wetzke M, Happle C, Kälble S, Scherer R, Kabesch M, Seifert R.

Allergy. 2016 Aug;71(8):1223-7. doi: 10.1111/all.12918. Epub 2016 May 30.

PMID:
27091647
24.

Doublesex and mab-3 related transcription factor 1 (DMRT1) is a sex-specific genetic determinant of childhood-onset asthma and is expressed in testis and macrophages.

Schieck M, Schouten JP, Michel S, Suttner K, Toncheva AA, Gaertner VD, Illig T, Lipinski S, Franke A, Klintschar M, Kalayci O, Sahiner UM, Birben E, Melén E, Pershagen G, Freidin MB, Ogorodova LM, Granell R, Henderson J, Brunekreef B, Smit HA, Vogelberg C, von Berg A, Bufe A, Heinzmann A, Laub O, Rietschel E, Simma B, Genuneit J, Jonigk D, Postma DS, Koppelman GH, Vonk JM, Timens W, Boezen HM, Kabesch M.

J Allergy Clin Immunol. 2016 Aug;138(2):421-31. doi: 10.1016/j.jaci.2015.12.1305. Epub 2016 Feb 20.

PMID:
26906082
25.

1,25D3 prevents CD8(+)Tc2 skewing and asthma development through VDR binding changes to the Cyp11a1 promoter.

Schedel M, Jia Y, Michel S, Takeda K, Domenico J, Joetham A, Ning F, Strand M, Han J, Wang M, Lucas JJ, Vogelberg C, Kabesch M, O'Connor BP, Gelfand EW.

Nat Commun. 2016 Jan 11;7:10213. doi: 10.1038/ncomms10213.

26.

The Early Development of Wheeze. Environmental Determinants and Genetic Susceptibility at 17q21.

Loss GJ, Depner M, Hose AJ, Genuneit J, Karvonen AM, Hyvärinen A, Roduit C, Kabesch M, Lauener R, Pfefferle PI, Pekkanen J, Dalphin JC, Riedler J, Braun-Fahrländer C, von Mutius E, Ege MJ; PASTURE (Protection against Allergy Study in Rural Environments) Study Group.

Am J Respir Crit Care Med. 2016 Apr 15;193(8):889-97. doi: 10.1164/rccm.201507-1493OC. Erratum in: Am J Respir Crit Care Med. 2019 Oct 1;200(7):946.

27.

Meta-analysis identifies seven susceptibility loci involved in the atopic march.

Marenholz I, Esparza-Gordillo J, Rüschendorf F, Bauerfeind A, Strachan DP, Spycher BD, Baurecht H, Margaritte-Jeannin P, Sääf A, Kerkhof M, Ege M, Baltic S, Matheson MC, Li J, Michel S, Ang WQ, McArdle W, Arnold A, Homuth G, Demenais F, Bouzigon E, Söderhäll C, Pershagen G, de Jongste JC, Postma DS, Braun-Fahrländer C, Horak E, Ogorodova LM, Puzyrev VP, Bragina EY, Hudson TJ, Morin C, Duffy DL, Marks GB, Robertson CF, Montgomery GW, Musk B, Thompson PJ, Martin NG, James A, Sleiman P, Toskala E, Rodriguez E, Fölster-Holst R, Franke A, Lieb W, Gieger C, Heinzmann A, Rietschel E, Keil T, Cichon S, Nöthen MM, Pennell CE, Sly PD, Schmidt CO, Matanovic A, Schneider V, Heinig M, Hübner N, Holt PG, Lau S, Kabesch M, Weidinger S, Hakonarson H, Ferreira MAR, Laprise C, Freidin MB, Genuneit J, Koppelman GH, Melén E, Dizier MH, Henderson AJ, Lee YA.

Nat Commun. 2015 Nov 6;6:8804. doi: 10.1038/ncomms9804.

28.

The cAMP response element modulator (CREM) regulates TH2 mediated inflammation.

Verjans E, Ohl K, Reiss LK, van Wijk F, Toncheva AA, Wiener A, Yu Y, Rieg AD, Gaertner VD, Roth J, Knol E, Kabesch M, Wagner N, Uhlig S, Martin C, Tenbrock K.

Oncotarget. 2015 Nov 17;6(36):38538-51. doi: 10.18632/oncotarget.6041.

29.

Atopic dermatitis is associated with an increased risk for rheumatoid arthritis and inflammatory bowel disease, and a decreased risk for type 1 diabetes.

Schmitt J, Schwarz K, Baurecht H, Hotze M, Fölster-Holst R, Rodríguez E, Lee YAE, Franke A, Degenhardt F, Lieb W, Gieger C, Kabesch M, Nöthen MM, Irvine AD, McLean WHI, Deckert S, Stephan V, Schwarz P, Aringer M, Novak N, Weidinger S.

J Allergy Clin Immunol. 2016 Jan;137(1):130-136. doi: 10.1016/j.jaci.2015.06.029. Epub 2015 Aug 4.

PMID:
26253344
30.

Confirmation of Host Genetic Determinants in the CFH Region and Susceptibility to Meningococcal Disease in a Central European Study Sample.

Biebl A, Muendlein A, Kinz E, Drexel H, Kabesch M, Zenz W, Elling R, Müller C, Keil T, Lau S, Simma B.

Pediatr Infect Dis J. 2015 Oct;34(10):1115-7. doi: 10.1097/INF.0000000000000823.

PMID:
26135246
31.

Childhood asthma is associated with mutations and gene expression differences of ORMDL genes that can interact.

Toncheva AA, Potaczek DP, Schedel M, Gersting SW, Michel S, Krajnov N, Gaertner VD, Klingbeil JM, Illig T, Franke A, Winkler C, Hohlfeld JM, Vogelberg C, von Berg A, Bufe A, Heinzmann A, Laub O, Rietschel E, Simma B, Genuneit J, Muntau AC, Kabesch M.

Allergy. 2015 Oct;70(10):1288-99. doi: 10.1111/all.12652. Epub 2015 Jul 20.

PMID:
26011647
32.

ORMDL deregulation increases stress responses and modulates repair pathways in Drosophila airways.

Kallsen K, Zehethofer N, Abdelsadik A, Lindner B, Kabesch M, Heine H, Roeder T.

J Allergy Clin Immunol. 2015 Oct;136(4):1105-8. doi: 10.1016/j.jaci.2015.04.009. Epub 2015 Jun 5. No abstract available. Erratum in: J Allergy Clin Immunol. 2017 Sep;140(3):894.

PMID:
25979522
33.

Different IgE recognition of mite allergen components in asthmatic and nonasthmatic children.

Resch Y, Michel S, Kabesch M, Lupinek C, Valenta R, Vrtala S.

J Allergy Clin Immunol. 2015 Oct;136(4):1083-91. doi: 10.1016/j.jaci.2015.03.024. Epub 2015 May 5.

34.

Polymorphisms related to ORMDL3 are associated with asthma susceptibility, alterations in transcriptional regulation of ORMDL3, and changes in TH2 cytokine levels.

Schedel M, Michel S, Gaertner VD, Toncheva AA, Depner M, Binia A, Schieck M, Rieger MT, Klopp N, von Berg A, Bufe A, Laub O, Rietschel E, Heinzmann A, Simma B, Vogelberg C, Genuneit J, Illig T, Kabesch M.

J Allergy Clin Immunol. 2015 Oct;136(4):893-903.e14. doi: 10.1016/j.jaci.2015.03.014. Epub 2015 Apr 28.

PMID:
25930191
35.

A genome-wide association study reveals 2 new susceptibility loci for atopic dermatitis.

Schaarschmidt H, Ellinghaus D, Rodríguez E, Kretschmer A, Baurecht H, Lipinski S, Meyer-Hoffert U, Harder J, Lieb W, Novak N, Fölster-Holst R, Esparza-Gordillo J, Marenholz I, Ruschendorf F, Hubner N, Reischl E, Waldenberger M, Gieger C, Illig T, Kabesch M, Zhang XJ, Xiao FL, Lee YA, Franke A, Weidinger S.

J Allergy Clin Immunol. 2015 Sep;136(3):802-6. doi: 10.1016/j.jaci.2015.01.047. Epub 2015 Apr 10. No abstract available.

PMID:
25865352
36.

Genome-wide comparative analysis of atopic dermatitis and psoriasis gives insight into opposing genetic mechanisms.

Baurecht H, Hotze M, Brand S, Büning C, Cormican P, Corvin A, Ellinghaus D, Ellinghaus E, Esparza-Gordillo J, Fölster-Holst R, Franke A, Gieger C, Hubner N, Illig T, Irvine AD, Kabesch M, Lee YA, Lieb W, Marenholz I, McLean WH, Morris DW, Mrowietz U, Nair R, Nöthen MM, Novak N, O'Regan GM; Psoriasis Association Genetics Extension, Schreiber S, Smith C, Strauch K, Stuart PE, Trembath R, Tsoi LC, Weichenthal M, Barker J, Elder JT, Weidinger S, Cordell HJ, Brown SJ.

Am J Hum Genet. 2015 Jan 8;96(1):104-20. doi: 10.1016/j.ajhg.2014.12.004. Erratum in: Am J Hum Genet. 2015 Dec 3;97(6):933.

37.

Fine-mapping of IgE-associated loci 1q23, 5q31, and 12q13 using 1000 Genomes Project data.

Sharma V, Michel S, Gaertner V, Franke A, Vogelberg C, von Berg A, Bufe A, Heinzmann A, Laub O, Rietschel E, Simma B, Frischer T, Genuneit J, Zeilinger S, Illig T, Schedel M, Potaczek DP, Kabesch M.

Allergy. 2014 Aug;69(8):1077-84. doi: 10.1111/all.12431. Epub 2014 Jun 14.

PMID:
24930997
38.

A polymorphism in the TH 2 locus control region is associated with changes in DNA methylation and gene expression.

Schieck M, Sharma V, Michel S, Toncheva AA, Worth L, Potaczek DP, Genuneit J, Kretschmer A, Depner M, Dalphin JC, Riedler J, Frei R, Pekkanen J, Tost J, Kabesch M.

Allergy. 2014 Sep;69(9):1171-80. doi: 10.1111/all.12450. Epub 2014 Jul 14.

PMID:
24866380
39.

Urban-rural differences in the gene expression profiles of Ghanaian children.

Amoah AS, Obeng BB, May L, Kruize YC, Larbi IA, Kabesch M, Wilson MD, Hartgers FC, Boakye DA, Yazdanbakhsh M.

Genes Immun. 2014 Jul-Aug;15(5):313-9. doi: 10.1038/gene.2014.21. Epub 2014 May 22.

PMID:
24848931
40.

A role of FCER1A and FCER2 polymorphisms in IgE regulation.

Sharma V, Michel S, Gaertner V, Franke A, Vogelberg C, von Berg A, Bufe A, Heinzmann A, Laub O, Rietschel E, Simma B, Frischer T, Genuneit J, Potaczek DP, Kabesch M.

Allergy. 2014 Feb;69(2):231-6. doi: 10.1111/all.12336. Epub 2013 Dec 20.

PMID:
24354852
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Epigenetics in asthma and allergy.

Kabesch M.

Curr Opin Allergy Clin Immunol. 2014 Feb;14(1):62-8. doi: 10.1097/ACI.0000000000000025. Review.

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Novel childhood asthma genes interact with in utero and early-life tobacco smoke exposure.

Scholtens S, Postma DS, Moffatt MF, Panasevich S, Granell R, Henderson AJ, Melén E, Nyberg F, Pershagen G, Jarvis D, Ramasamy A, Wjst M, Svanes C, Bouzigon E, Demenais F, Kauffmann F, Siroux V, von Mutius E, Ege MJ, Braun-Fahrländer C, Genuneit J; GABRIELA study group, Brunekreef B, Smit HA, Wijga AH, Kerkhof M, Curjuric I, Imboden M, Thun GA, Probst-Hensch N, Freidin MB, Bragina EIu, Deev IA, Puzyrev VP, Daley D, Park J, Becker A, Chan-Yeung M, Kozyrskyj AL, Pare P, Marenholz I, Lau S, Keil T, Lee YA, Kabesch M, Wijmenga C, Franke L, Nolte IM, Vonk J, Kumar A, Farrall M, Cookson WO, Strachan DP, Koppelman GH, Boezen HM.

J Allergy Clin Immunol. 2014 Mar;133(3):885-8. doi: 10.1016/j.jaci.2013.08.049. Epub 2013 Dec 6. No abstract available.

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Clinical and epidemiologic phenotypes of childhood asthma.

Depner M, Fuchs O, Genuneit J, Karvonen AM, Hyvärinen A, Kaulek V, Roduit C, Weber J, Schaub B, Lauener R, Kabesch M, Pfefferle PI, Frey U, Pekkanen J, Dalphin JC, Riedler J, Braun-Fahrländer C, von Mutius E, Ege MJ; PASTURE Study Group.

Am J Respir Crit Care Med. 2014 Jan 15;189(2):129-38. doi: 10.1164/rccm.201307-1198OC.

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Regulation of TH17 markers early in life through maternal farm exposure.

Lluis A, Ballenberger N, Illi S, Schieck M, Kabesch M, Illig T, Schleich I, von Mutius E, Schaub B.

J Allergy Clin Immunol. 2014 Mar;133(3):864-71. doi: 10.1016/j.jaci.2013.09.030. Epub 2013 Nov 23.

PMID:
24275363
45.

Rule-based models of the interplay between genetic and environmental factors in childhood allergy.

Bornelöv S, Sääf A, Melén E, Bergström A, Torabi Moghadam B, Pulkkinen V, Acevedo N, Orsmark Pietras C, Ege M, Braun-Fahrländer C, Riedler J, Doekes G, Kabesch M, van Hage M, Kere J, Scheynius A, Söderhäll C, Pershagen G, Komorowski J.

PLoS One. 2013 Nov 19;8(11):e80080. doi: 10.1371/journal.pone.0080080. eCollection 2013.

46.

Genetic variation in TH17 pathway genes, childhood asthma, and total serum IgE levels.

Schieck M, Michel S, Suttner K, Illig T, Zeilinger S, Franke A, Vogelberg C, von Berg A, Bufe A, Heinzmann A, Laub O, Rietschel E, Simma B, Frischer T, Genuneit J, Kerzel S, Kabesch M.

J Allergy Clin Immunol. 2014 Mar;133(3):888-91. doi: 10.1016/j.jaci.2013.08.048. Epub 2013 Nov 1. No abstract available.

PMID:
24184148
47.

The crystal structure of lipopolysaccharide binding protein reveals the location of a frequent mutation that impairs innate immunity.

Eckert JK, Kim YJ, Kim JI, Gürtler K, Oh DY, Sur S, Lundvall L, Hamann L, van der Ploeg A, Pickkers P, Giamarellos-Bourboulis E, Kubarenko AV, Weber AN, Kabesch M, Kumpf O, An HJ, Lee JO, Schumann RR.

Immunity. 2013 Oct 17;39(4):647-60. doi: 10.1016/j.immuni.2013.09.005. Epub 2013 Oct 10.

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Tmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjects.

Saunders SP, Goh CS, Brown SJ, Palmer CN, Porter RM, Cole C, Campbell LE, Gierlinski M, Barton GJ, Schneider G, Balmain A, Prescott AR, Weidinger S, Baurecht H, Kabesch M, Gieger C, Lee YA, Tavendale R, Mukhopadhyay S, Turner SW, Madhok VB, Sullivan FM, Relton C, Burn J, Meggitt S, Smith CH, Allen MA, Barker JN, Reynolds NJ, Cordell HJ, Irvine AD, McLean WH, Sandilands A, Fallon PG.

J Allergy Clin Immunol. 2013 Nov;132(5):1121-9. doi: 10.1016/j.jaci.2013.08.046. Epub 2013 Sep 29. Erratum in: J Allergy Clin Immunol. 2015 Dec;136(6):1710.

49.

Polymorphisms in the IRF-4 gene, asthma and recurrent bronchitis in children.

Pinto LA, Michel S, Klopp N, Vogelberg C, von Berg A, Bufe A, Heinzmann A, Laub O, Simma B, Frischer T, Genuneit J, Gorski M, Illig T, Kabesch M.

Clin Exp Allergy. 2013 Oct;43(10):1152-9. doi: 10.1111/cea.12175.

PMID:
24074333
50.

STAT6 polymorphisms are associated with neonatal regulatory T cells and cytokines and atopic diseases at 3 years.

Casaca VI, Illi S, Klucker E, Ballenberger N, Schedel M, von Mutius E, Kabesch M, Schaub B.

Allergy. 2013 Oct;68(10):1249-58. doi: 10.1111/all.12220. Epub 2013 Sep 21.

PMID:
24053457

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